Clinical trials: Covid-19 Patients
COVID 19 Disease
Tafenoquine in Patients With Mild to Moderate COVID-19
A clinical study to assess the efficacy and safety of oral tafenoquine compared to placebo in patients with mild to moderate COVID 19 disease.
- Trial name
- NCT04533347
- Testing
- Tafenoquine Oral Tablet
- Where
- 10 sites in United States
- Volunteers
- 86 people
- Sponsor
- 60 Degrees Pharmaceuticals LLC
COVID-19
Thorax Computed Tomography Severity Score and Outcome in COVID-19 Patients
The most common thorax Computed tomography (CT) findings are multifocal ground-glass opacities and peripheral consolidation in patients with COVID-19.
- Trial name
- NCT04424849
- Testing
- CT-Scan
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Tepecik Training and Research Hospital
Obesity
Pharmacokinetics of Dexamethasone in COVID-19 Obese Patients
In this regard, the present research project aims to compare dexamethasone PK in normal-weight versus obese patients treated for COVID-19.
- Trial name
- CoDEX (NCT04996784)
- Testing
- Capillary blood sampling
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Jules Desmeules
Severe Acute Respiratory Syndrome Coronavirus 2, SARS-CoV2
Ruxolitinib for Acute Respiratory Disorder Syndrome Due to COVID-19
The COVID-19 pandemic has had a dramatic effect in public health worldwide. In Brazil, there have been more than 2 million confirmed cases and over 75,000 deaths since February 26, 2020.
- Trial name
- RUXO-COVID (NCT04477993)
- Testing
- Janus Kinase Inhibitor (ruxolitinib)
- Where
- Brazil
- Volunteers
- 5 people
- Sponsor
- Vanderson Geraldo Rocha
COVID-19, Pulmonary Fibrosis
Comparison of Pulmonary Telerehabilitation and Physical Activity Recommendations in Patients With Post Covid Fibrosis
Rehabilitation plays a very important role in the management of patients with COVID-19, focusing on respiratory and motor functions, and therefore the importance of establishing treatment strategies to ensure optimal recovery of…
- Trial name
- NCT05299333
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul University - Cerrahpasa
SARS-CoV Infection, SARS (Severe Acute Respiratory Syndrome)
High Flow Nasal Cannula HFNC In Covid-19 Patients
Many non-invasive ventilatory choices are available for COVID-19 patient who are having mild to moderate respiratory distress and their use will decrease the chance of ICU admission, intubation and mechanical ventilation in…
- Trial name
- HFNC19LGH (NCT04560257)
- Testing
- High flow nasal cannula HFNC
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Lahore General Hospital
Covid19
Essential Amino Acid Supplementation in Older Adult COVID-19 Patients
A 4-week treatment of essential amino acids or placebo to participants with: 1) negative COVID-19 test with exposure, or 2) positive COVID-19 test and no or mild symptoms. The study team will measure change in symptoms.
- Trial name
- NCT04816071
- Testing
- Essential amino acids, Maltodextrin
- Where
- United States
- Sponsor
- University of Arkansas
Long COVID, Post-Acute COVID-19 Syndrome
A Study of Amantadine for Cognitive Dysfunction in Patients With Long-Covid
Purpose: To decrease symptom burden, improve cognitive function, improve endurance, and decrease fatigue in subjects with post-acute sequelae of COVID-19 (PASC) or "long-hauler" COVID using amantadine.
- Trial name
- NCT06234462
- Testing
- Amantadine, Physical, Occupational, Speech Therapy, Provider Counseling
- Where
- United States
- Sponsor
- University of Texas Southwestern Medical Center
Post-Acute COVID-19 Syndrome, Post-Acute COVID-19
Safety and Efficacy of Anakinra Treatment for Patients With Post Acute Covid Syndrome
The PRECISION is a proof-of-concept, phase II randomized clinical trial aiming to evaluate the efficacy and safety of anakinra in patients with Post-Acute COVID Syndrome (PACS) of the pro-inflammatory respiratory phenotype.
- Conditions
- Post-Acute COVID-19 Syndrome, Post-Acute COVID-19, Long COVID
- Trial name
- PRECISION (NCT05926505)
- Testing
- Anakinra 149 MG/ML Prefilled Syringe [Kineret]
- Where
- 24 sites in Germany, Greece and 2 more
- Volunteers
- 182 people
- Sponsor
- Hellenic Institute for the Study of Sepsis
Covid19
Efficacy of a Nasal Spray Containing Iota-Carrageenan in the Prophylaxis of COVID-19 Disease in Health Personnel Dedicated to Patients Care With COVID-19 Disease
Coronaviruses are enveloped viruses with an RNA genome. Carrageenans are sulfate polysaccharides synthesized by red algae. Studies conducted in adults and children with the common cold showed the effectiveness of the use of…
- Trial name
- CARR-COV-02 (NCT04521322)
- Testing
- Iota-Carrageenan
- Where
- Argentina
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Ariel Dogliotti
Aerobic Exercise, Strength Training
Home-Based Circuit Training in Overweight/Obese Older Adult Patients With Knee Osteoarthritis and Type 2 Diabetes
Background: Obesity and type 2 diabetes mellitus (T2DM) are considered two of the most prevalent metabolic diseases linked to the onset of knee pain caused by osteoarthritis.
- Conditions
- Aerobic Exercise, Strength Training, Glycemic Control, Blood Pressure
- Trial name
- NCT06309654
- Testing
- 12-week home-based circuit training (HBCT), Standard of care (CONT)
- Where
- Saudi Arabia
- Volunteers
- 70 people
- Sponsor
- Princess Nourah Bint Abdulrahman University
Covid19
Electrocardiographic QRS Axis Shift ,Rotation and COVİD-19
In patients with coronavirus disease (COVID-19), severe dyspnea is the most dramatic complication.Severe respiratory difficulties may include electrocardiographic frontal QRS axis rightward shift (Rws) and clockwise rotation…
- Trial name
- NCT04698083
- Testing
- Electrocardiography ,Tomographic imaging
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Ankara Education and Research Hospital
Surgical Procedures, Operative, COVID-19
The Impact of the COVID-19 Pandemic on the Patient in Need of an Intervention
Mixed-method observational study: the impact of pandemic related changes in healthcare on quality of life and experiences with healthcare in Dutch patients undergoing surgery or another intervention during the covid pandemic…
- Conditions
- Surgical Procedures, Operative, COVID-19, SARS-CoV-2
- Trial name
- COVID Surg III (NCT05736822)
- Where
- Netherlands
- Volunteers
- 5,277 people
- Sponsor
- University Medical Center Groningen
COVID-19 Pneumonia, Impaired Respiratory Function
Study of Efficacy and Safety of MAS825 in Patients With COVID-19
This clinical study was designed to assess the efficacy and safety of MAS825 for the treatment of severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) infected patients with coronavirus disease 2019 (COVID-19) pneumonia…
- Trial name
- MAS-COVID (NCT04382651)
- Testing
- MAS825, Standard of Care (SoC)
- Where
- 21 sites in United States
- Volunteers
- 140 people
- Sponsor
- Novartis Pharmaceuticals
Myeloproliferative Disease, COVID - 19
Autoantibodies Against Type I Interferon in Patients Affected With Ph-negative Myeloproliferative Neoplasms (MPN-IFN Study)
The classic Ph-negative myeloproliferative neoplasms (MPN) are a group of clonal hematopoietic disorders caused by a dysregulated JAK/STAT signal transduction because of acquired somatic mutations of JAK2, CALR or MPL genes.
- Trial name
- NCT07204366
- Where
- Italy
- Volunteers
- 219 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Covid19, Cancer
Serologic Response to the SARS-CoV-2 (COVID-19) MRNA-1273 Vaccine in Select Subsets of Oncology Patients
To explore the immune response to the COVID-19 vaccine in cancer patients and compare to the general population.
- Trial name
- NCT04854980
- Testing
- Blood Sample
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Rochester
COVID-19 (Coronavirus Disease 2019)
Physiological Finding in Management of COVID 19 Patients
This study utilizes physiological indicators of COVID-19 patients as tools for assessing, tracking, worsening, and improving the clinical symptoms of COVID-19 patients.
- Trial name
- COVID-19 (NCT07504341)
- Testing
- physiological parameters
- Where
- 2 sites in Taiwan
- Volunteers
- 15,000 people
- Sponsor
- St. Martin De Porress Hospital
Economic Burden
Covid -19 Pandemic: Economic Burden on Patients Operated for Traumatic Close Fractures
Covid-19 has adversely impacted the health care organizations by over burdening with Covid patients and suspending the elective surgeries and clinics A single center retrospective study was conducted to quantify losses due to…
- Trial name
- NCT04482205
- Where
- Pakistan
- Volunteers
- 840 people
- Sponsor
- Aga Khan University
COVID-19, Pregnancy Related
Evaluation of Hand Grip Strength in Pregnant COVID-19 Patients
It was presented as a cross-sectional, single-center, retrospective case series. Pregnant women with a positive Polymerase Chain Reaction (PCR) diagnosis of Covid 19 were included in the study.
- Trial name
- NCT05970874
- Testing
- Hand grip strength measureme
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people
- Sponsor
- Karaman Training and Research Hospital
Coronavirus Disease 2019 )COVID-19)
Early transfusIon of Convalescent Plasma in Elderly COVID-19 Patients. to Prevent Disease Progression.
Older age is an independent poor outcome predictor among COVID-19 hospitalized patients . Among 72,314 COVID-19 cases, case fatality rate (CFR) was 2.3% in total population, 8% in people aged 70 to 79, and 14.8% in those aged 80…
- Trial name
- LIFESAVER (NCT04374526)
- Testing
- COVID-19 Convalescent Plasma
- Where
- 3 sites in Italy
- Volunteers
- 29 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
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