Clinical trials: Covid-19 Patients
Mechanical Ventilation Duration
Interleukine 6 as a Predictor of Outcome in Mechanically Ventilated Patients With Covid 19
Serum IL-6 levels will be determined by enzyme-linked immunosorbent assay according to the manufacturer's instructions and the normal range is <10 pg/mL , Patients' medical records will be carefully reviewed and analyzed.
- Trial name
- NCT05274503
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Liver Diseases, COVID19
COVID19-FOIE National Observatory
Background: The COVID19 and liver relationships are very rare. The preliminary Chinese data indicate that 2-11% of patients treated for COVID19 had an underlying chronic liver disease.
- Trial name
- NCT04375670
- Where
- France
- Volunteers
- 1,132 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Coronavirus, COVID
A Phase 2 Study to Evaluate Axatilimab for Hospitalized Participants With Respiratory Involvement Secondary to COVID-19
This was a randomized, double-blind, placebo-controlled, 29-day study to assess the efficacy and safety of axatilimab plus standard of care (SOC), compared with placebo plus SOC, in participants with respiratory signs and…
- Conditions
- Coronavirus, COVID, ARDS, Cytokine Storm
- Trial name
- NCT04415073
- Testing
- SNDX-6352
- Where
- 2 sites in United States
- Volunteers
- 1 people
- Sponsor
- Syndax Pharmaceuticals
Covid19
Comparing the Effects of Different Doses of Dexamethasone to Treat Inpatient COVID-19
This open label clinical trial is to evaluate two different doses of dexamethasone on the health outcome using World Health Organization ordinal scale at day 28 in hospitalized patients with COVID-19.
- Trial name
- NCT04707534
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of Oklahoma
COVID-19 (Coronavirus Disease 2019)
A US Study to Look at Loss of Work and Healthcare Costs for People Affected With Mild-to-moderate COVID 19 Who Have High Chances of the Disease Becoming Severe
The purpose of this study is to understand how COVID-19 affects people's ability to work and to calculate the costs associated with loss of work.
- Trial name
- NCT07072793
- Testing
- nirmatrelvir-ritonavir
- Where
- United States
- Volunteers
- 131,005 people
- Sponsor
- Pfizer
Acute Respiratory Distress Syndrome, COVID-19 Acute Respiratory Distress Syndrome
A Randomized Study to Investigate the Effect of Intravenous Imatinib on the Amount of Oxygen in the Lungs and Blood of Adults With COVID-19 Needing Mechanical Ventilation and Supportive Care.
The COVID-19 pandemic has led to an increase in the number of patients admitted to intensive care units (ICU) with acute respiratory distress syndrome (ARDS).
- Conditions
- Acute Respiratory Distress Syndrome, COVID-19 Acute Respiratory Distress Syndrome, Covid19, ARDS
- Trial name
- IMPRESS COVID (NCT04953052)
- Testing
- Imatinib Mesylate
- Where
- 8 sites in India
- Sponsor
- Exvastat Ltd.
Post-Acute COVID19 Syndrome, Long COVID
Exercise Intervention Using mHealth in Patients With Post-Acute COVID-19 Syndrome: a Randomized Clinical Trial
Post-Acute Syndrome COVID-19 is a disease resulting from infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
- Conditions
- Post-Acute COVID19 Syndrome, Long COVID, Post COVID-19 Condition
- Trial name
- COVIDReApp (NCT05725538)
- Testing
- COVIDReApp Group, Control Group
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- University of Cadiz
COVID-19
Non-comparative Trial of the Combination of HCQ and AZI in the Treatment of ICU Patients
This research is designed as an open-label,non-comparative prospective trial.
- Trial name
- NCT04458948
- Testing
- Hydroxychloroquine, Azithromycin
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of New Mexico
Coronavirus Infection
Clinical Evaluation of Cordio Application in Adult COVID-19 Virus Positive Patients
Study on adult patients positive to COVID-19 virus. After signing informed consent and undergoing screening assessments, eligible patients will record few times a day several pre-defined sentences to the Cordio App installed in a…
- Trial name
- NCT04325048
- Testing
- Cordio App
- Where
- Israel
- Volunteers
- 42 people
- Sponsor
- Cordio Medical
COVID-19
Correlation Between Thoracic Ultrasound and Thorax Computed Tomography Scores.
Coronavirus Disease 19 (COVID-19) pandemic has become a global health problem in a short time due to high infection rate and increasing mortality.
- Trial name
- NCT04577235
- Testing
- severity of lung involvement with COVID-19.
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
SARS-CoV 2, COVID
Precision Immunology to Determine the Immune Response in Patients With COVID-19
To better understand the immune response to SARS-CoV-2 infection, we devised a precision immunology approach to systematically study the immune function of different patient cohorts
- Trial name
- NCT04360733
- Testing
- Blood draw
- Where
- Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Bonn
COVID-19
Observational Study, Use of Canakinumab Administered Subcutaneously in the Treatment COVID-19 Pneumonia
The study is configured as a retrospective and prospective observational study. The study will be multi-center and will involve all COVID-19 pneumonia patients treated with canakinumab administered subcutaneously.
- Trial name
- NCT04348448
- Testing
- Canakinumab 150 MG/ML [Ilaris]
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- AUSL Romagna Rimini
COVID-19, Viral Pneumonia
Low-doses Melphalan Inhalation in Patients With COVID-19 (CoronavIrus Disease 2019) Pneumonia
This single-center, prospective, open-label, comparator study, blind for central accessor evaluates the efficacy, safety of inhalations of low-doses of melphalan in patients with pneumonia with confirmed or suspected COVID-19.
- Trial name
- MICOV (NCT04380376)
- Testing
- Melphalan, Standard of care
- Where
- 2 sites in Russia
- Volunteers
- 60 people
- Sponsor
- Federal State Budgetary Institution, Pulmonology Scientific Research Institute
COVID-19 Patient
A Real-world Retrospective Study of Disease Outcomes in Non-severe COVID-19 Patient
Retrospective analysis of real-world disease outcomes in non-severe COVID-19 patients with high risk factors of progression to severe disease, including death, without definitive anti-SARS-CoV-2 treatment
- Trial name
- NCT05489874
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Shanghai Vinnerna Biosciences Co., Ltd.
Pleth Variability Index
Evaluation of the Fluid Response of SARS-CoV-2 (COVID-19) Patients in Intensive Care; Pleth Variability Index
In this study; We aimed to investigate the role of pleth variability index, which is a noninvasive method, in showing fluid response in SARS-CoV-2 (COVID-19) patients, which we know is appropriate fluid management.
- Trial name
- NCT04373213
- Testing
- Pleth variability index
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Erzincan University
Feeding and Eating Disorders
Impact of COVID-19 Lockdown on Obesity and Eating Behaviors
COVID-19 lockdown presents particular challenges for people living with obesity. Indeed during this period, the lifestyle was deeply modified: diet, activity, and sleep behaviours, home office, take care of child, social…
- Trial name
- CIO (NCT04431284)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Hospices Civils de Lyon
COVID-19 Pandemic, Diabetes
Study on the Effect of Incentive Spirometer-based Respiratory Training on the Long COVID-19
The COVID-19 pandemic has emerged as the most significant public health crisis of the 21st century. As of the end of January 2023, global confirmed cases have exceeded 670 million, with a domestic cumulative total of 10.24…
- Conditions
- COVID-19 Pandemic, Diabetes, Hypertension, Cardiac Disease
- Trial name
- NCT06231225
- Testing
- Incentive Spirometer respiratory training
- Volunteers
- 100 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
COPD, COVID-19
Impact of COVID-19 on Lung Function in COPD Patients.
Background: In 2019, a novel coronavirus (SARS-COV2) was detected in Wuhan, China as a cause of acute respiratory distress syndrome (COVID-19).
- Trial name
- EspirCOVID (NCT05770440)
- Where
- Spain
- Volunteers
- 250 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Covid19, Pediatric ALL
Pediatric Intensive Care and COVID-19
In this prospective longitudinal cohort the investigators reported the clinical, and biological characteristics of all critically ill patients admitted in the pediatric intensive care unit (PICU) of Bicêtre Hospital during the…
- Conditions
- Covid19, Pediatric ALL, Infection, Critical Illness
- Trial name
- CLOVIS (NCT04544878)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Bicetre Hospital
Post-acute COVID-19 Syndrome
SENSING-AI Cohort for Long COVID Patients
The prospective study will focus on the collection of biometric and psychometric data from a limited population for 1 month with the aim of complementing the SENSING-AI retrospective cohort.
- Trial name
- SENSING-AI (NCT05204615)
- Testing
- Collection of clinical, psychometric and biometric data
- Where
- 2 sites in Spain
- Volunteers
- 10 people
- Sponsor
- Adhera Health, Inc.
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