Clinical trials: Covid-19 Patients
COVID-19, SARS-CoV 2
CONVALESCENT PLASMA FOR ILL PATIENTS BY COVID-19
The present study will try to respond first in an initial phase, what is the minimum effective dose necessary of convalescent plasma for getting better in severly ill (not intubated) or very severely ill (intubated) patients.
- Conditions
- COVID-19, SARS-CoV 2, Convalescence, Plasma
- Trial name
- COPLASCOV19 (NCT04356482)
- Testing
- convalescent plasma
- Where
- 3 sites in Mexico
- Volunteers
- 90 people
- Sponsor
- Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado
Covid19
Genetic Predisposition to Severe Forms of COVID-19 (SARS-CoV2 Infection)
The main objective of this part of the project is to identify the germline genetic factors which discriminate the benign and severe forms of SARS-CoV2 (CoVID-19) infection in the context of the ongoing SARS-CoV2 (HCOVID-19)…
- Trial name
- COVIDGEN (NCT04644146)
- Testing
- GENETIC
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Covid19, Chronic Respiratory Disease
Clinical Characteristics And Outcome Of COVID-19 Infection In Patients With Chronic Respiratory Diseases.
1. To identify the pattern of presentation of COVID-19 in patients with chronic respiratory diseases 2. To asses the severity of COVID-19 in patients with chronic respiratory diseases 3.
- Trial name
- NCT05054127
- Testing
- foiiow up patients
- Volunteers
- 100 people
- Sponsor
- Assiut University
COVID-19 Vaccines, Autoimmune Diseases
Effectiveness and Safety of the Inactivated COVID-19 Vaccine in Thousands of Patients With Autoimmune Diseases in China
According to the comprehensive evaluation, the completion of vaccination and the prevention and treatment strategy of integrated traditional Chinese and western medicine have obvious advantages in improving the symptoms of…
- Trial name
- NCT05831826
- Testing
- the inactivated COVID-19 vaccines
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Zhejiang Chinese Medical University
COVID-19
Cyclosporine in Patients With Moderate COVID-19
Phase 1 safety study to determine the tolerability, clinical effects, and changes in laboratory parameters of short course oral or IV cyclosporine (CSA) administration in patients with COVID-19 disease requiring oxygen…
- Trial name
- NCT04412785
- Testing
- Cyclosporine
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Pennsylvania
COVID-19, Severe Acute Respiratory Syndrome Coronavirus 2
Monocytes and NK Cells Activity in Covid-19 Patients
SARS-CoV-2 belong to beta-coronavirus family and its transmission route and symptoms follow those of all community-acquired coronaviruses.
- Conditions
- COVID-19, Severe Acute Respiratory Syndrome Coronavirus 2, Immunomodulation
- Trial name
- NCT04375176
- Testing
- Study of immune-mediated mechanisms in patients tested positive for SARS-CoV-2
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Università degli Studi dell'Insubria
Long COVID
Exercise for Health in Patients With Post-acute Sequelae of COVID-19
Background: Many patients with COVID-19 present the so-called post-acute sequelae of COVID-19 such as fatigue, post-stress discomfort, dyspnea, headache, pain mental impairment, incapacity to perform daily physical tasks ant…
- Trial name
- EJerSA-COVID (NCT05848518)
- Testing
- Rehabilitation program
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Campus docent Sant Joan de Déu-Universitat de Barcelona
Covid19
Impact of Steroids on Inflammatory Response in Covid-19
we designed this study to observe the efficacy and safety of dexamethasone versus methylprednisolone in covid-19 diseased patients upon monitoring the inflammatory response and to compare the outcome when these steroids will be…
- Trial name
- NCT04909918
- Testing
- Dexamethasone, Methylprednisolone
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Covid-19
Neuroradiolological Analysis of COVID-19 Patients
To describe the radiological presentation of brain abnormalities in COVID-19 + patients
- Trial name
- NEURO-COVID-19 (NCT04368390)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Covid19
Study Project Comparing the Sequelae of COVID-19 Infection in Patients Who Have and Have Not Received Ventilatory Support in Critical Care
To assess the proportion of post-intensive care syndrome (PICS) of patients who received high flow humidified oxygen with FiO2 ≥50% for more than 48h and / or who received mechanical ventilation for more than 48h in a context of…
- Trial name
- COMEBAC (NCT04704388)
- Where
- France
- Volunteers
- 478 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
COVID-19
A Follow-up Study of Asymptomatic Infections and Diagnosed Patients With Covid-19 in Shanghai
This study is to clarify the distribution characteristics, host and clinical characteristics, disease outcome and risk factors, changes of multiple organs such as cardiopulmonary function and changes in social and psychological…
- Trial name
- NCT05387304
- Where
- China
- Volunteers
- 250,000 people
- Sponsor
- Ruijin Hospital
COVID-19, SARS-CoV 2
Convalescent Plasma for the Treatment of Patients With COVID-19
This expanded access program will provide access to COVID-19 convalescent plasma 150 or more individuals with moderate to severe or life-threatening manifestations of COVID-19, or documented to be at high risk of developing such…
- Trial name
- NCT04372368
- Testing
- COVID-19 Convalescent Plasma
- Where
- 6 sites in United States
- Sponsor
- University of Colorado, Denver
SARS-CoV2 Infection, COVID-19 Acute Respiratory Distress Syndrome
Impact of COVID-19 SARS-CoV-2 Variability in ICU Hospitalized Patients With Severe Disease
Background:The impact of the emergence of SARS-CoV-2 variants on the severity and clinical outcomes of COVID-19 is controversial.
- Conditions
- SARS-CoV2 Infection, COVID-19 Acute Respiratory Distress Syndrome, Mutation
- Trial name
- SEVARVIR (NCT05162508)
- Testing
- Nasopharyngeal swab
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Long Covid19
Chronic-disease Self-management Program in Patients Living With Long-COVID in Puerto Rico
This is a pilot non-randomized-controlled trial to evaluate the impact of "Tomando control de su salud", an evidenced-based intervention for chronic disease self-management in the quality of life of patients living with…
- Trial name
- NCT06208696
- Testing
- "Tomando control de su salud" (Spanish Chronic Disease Self-Management)
- Where
- Puerto Rico
- Volunteers
- 47 people
- Sponsor
- University of Puerto Rico
Covid19
RespiraConNosotros:a Mobile Application for COVID-19 Respiratory Rehabilitation.
Platform with a mobile application to encourage the performance of respiratory exercises, controlled and supervised by physiotherapists.
- Trial name
- NCT04703478
- Testing
- Breathing exercise
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- University of Salamanca
SARS CoV 2 Infection, Cancer
Mortality of Cancer Surgery During SARS CoV2 Pandemic
The impact of cancer surgery during covid epidemic is not clear. The published reports show contradictory findings that extend from no change in mortality to increased mortality, further no data on exposure and outcome of health…
- Trial name
- NCT05240378
- Testing
- Surgery
- Where
- India
- Volunteers
- 1,576 people
- Sponsor
- Banaras Hindu University
Simulation of Physical Illness, Satisfaction
High-Fidelity Simulation Training: A Mixed Method Study
The goal of this clinical trial is to compare in describe first-year nursing students' skills. The main questions it aims to answer are: Are nursing students who perform the simulation practice with the scenario-based…
- Trial name
- NCT05630391
- Testing
- High-Fidelity Simulation Manikin, Education
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Low Back Pain, Mechanical
Physical Deconditioning in COVID-19 Positive Patients and Non-Specific Low Back Pain
The purpose of this study is to take advantage of cohorts of patients followed for Coronavirus Disease 2019 (COVID19) expected to present poor physical fitness as the consequence of COVID19 to explore the relationship between…
- Trial name
- Phydel (NCT04990518)
- Where
- Switzerland
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
COVID-19 Patients, Hypoxemic Respiratory Failure
Awake Prone Positioning in COVID-19 Suspects With Hypoxemic Respiratory Failure
The investigator hypothesis is that early implementation of early, awake prone position for patients with COVID-19 pneumonia requiring oxygen therapy will reduce the need for escalation of respiratory support.
- Conditions
- COVID-19 Patients, Hypoxemic Respiratory Failure, Prone Position
- Trial name
- NCT04853979
- Testing
- PRONE POSITION
- Where
- Qatar
- Volunteers
- 61 people
- Sponsor
- Hamad Medical Corporation
Severe Acute Respiratory Syndrome Coronavirus 2, COVID-19
CORONA (COvid pRONe hypoxemiA): Prone Positioning for Hypoxemic COVID-19 Patients With Do-not-intubate Goals
The purpose of this trial is to determine whether Prone Positioning (PP) improves outcomes for non-intubated hospitalized patients with hypoxemic respiratory failure due to COVID-19, who are not candidates for mechanical…
- Conditions
- Severe Acute Respiratory Syndrome Coronavirus 2, COVID-19, Acute Respiratory Distress Syndrome, ARDS
- Trial name
- CORONA (NCT04402879)
- Testing
- Prone Positioning (PP)
- Where
- 4 sites in Canada
- Volunteers
- 596 people
- Sponsor
- University of Calgary
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