Clinical trials: Covid-19 Patients
Postoperative Complications, Appendicitis
Impact of SARS-Cov2 Pandemic on Severity of Perioperative Complications in Patients Undergoing Appendectomy
There are 2 types of surgical procedures to remove the appendix : open appendectomy or laparoscopic appendectomy. About 60000 appendectomies are performed every year in France.
- Conditions
- Postoperative Complications, Appendicitis, COVID-19 Pandemic, Appendicitis With Peritonitis
- Trial name
- SAP-19 (NCT05178251)
- Testing
- appendectomy
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Central Hospital, Nancy, France
Disease, Viral, Cytokine Release Syndrome
Th1/Th2/Th17/TREG and TLRs Activation/KIR for COVID 19 Prediction of Outcome
To ascertain globally the changes in the cytokines involved and TLRs/KIR activation in patients admitted to the hospital with a COVID-19 diagnosis, and the changes after initiation of the different therapies
- Conditions
- Disease, Viral, Cytokine Release Syndrome, TLRs
- Trial name
- Resistir (NCT04403061)
- Testing
- Cytokines measurement, Cellular response, TLRs activation measurement
- Where
- Spain
- Volunteers
- 106 people
- Sponsor
- Asociacion para el Estudio de las Enfermedades Infecciosas
Bariatric Surgery, Obesity
Home-based Exercise Training During Covid-19 Pandemic in Post-bariatric
The aim of this study is to assess the effect of a home-based exercise training during social isolation due to covid-19 pandemic in patients who undertook bariatric surgery.
- Trial name
- NCT04425005
- Testing
- Home-based exercise
- Where
- Brazil
- Volunteers
- 55 people
- Sponsor
- University of Sao Paulo
Chronic Kidney Diseases, COVID-19
COVID-19 Vaccine Boosters in Patients With CKD
This study is a 12-month, four-arm parallel-group randomized control trial of Pfizer-BioNTech versus MODERNA COVID-19 (Corona Virus disease 2019)vaccine boosters in chronic kidney disease and dialysis patients with poor humoral…
- Trial name
- BOOST KIDNEY (NCT05022329)
- Testing
- Pfizer-BioNTech COVID-19 Vaccine, MODERNA SARS-CoV-2 Vaccine
- Where
- 3 sites in Canada
- Volunteers
- 273 people
- Sponsor
- Sunnybrook Health Sciences Centre
Covid19
Role of the Microbiota in the Evolution of the SARS-CoV-2 Disease,COVID-19, in Hospitalized Patients
Patients hospitalized for COVID-19 may need intensive care (e.g. mechanical ventilation) during hospitalization. Some risk factors are already known but better targeting of such patients is still needed, at least because existing…
- Trial name
- MicrobioCOVID (NCT04669938)
- Testing
- oropharyngeal and intestinal microbiota, host genotype, host immune factors
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Motor Neuropathy, Sensory Neuropathy
Short-term Evaluation of Motor and Sensory Function in Post-COVID-19 Patients
SARS-COV-2 infection reframed medical knowledge in many aspects, yet there is still a lot to be discovered. our aim is to evaluate neurological impact of covid-19; if there is any.
- Trial name
- NCT05721040
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Corona Virus Infection
Effect of Aerobics and Balancing Exercises on Anxiety and Dizziness in Patients With COVID-19
The recently emerged coronavirus named Severe Acute Respiratory Syndrome Coronavirus 2 (SARSCoV-2) is the newest threat to human health.
- Trial name
- NCT04996225
- Testing
- Aerobics exercises, Balance exercises
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Merit University
Critical Illness, Sedation Complication
Sedation, ANalgesia and Delirium MANagement in Intensive Care Unit
Patients with acute severe health problems often need to be admitted to specialised hospital wards called Intensive Care Units (ICUs) where they can receive emergency treatment such as mechanical ventilation to support their…
- Conditions
- Critical Illness, Sedation Complication, Intensive Care Unit Delirium, Analgesia
- Trial name
- SAnDMAN (NCT05027217)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 3,421 people
- Sponsor
- University of Oxford
COVID-19
Emergency Ventilator Splitting Between Two or More Patients (COVID-19)
The purpose of this study is to develop a safe, easily scalable, and simple method to split a single ventilator for use amongst two or more patients, thus serving as a capacity bridge to save patient lives until manufacturers can…
- Trial name
- NCT04381013
- Testing
- Emergency Ventilator Splitter
- Where
- United States
- Sponsor
- Stanford University
Covid19, Pneumonia, Viral
Prone Position and Respiratory Outcomes in Non-Intubated COVID-19 PatiEnts The "PRONE" Study
The overall objective of this study is to determine whether a positional maneuver (e.g., prone positioning) decreases the need for escalation of respiratory-related care in patients with coronavirus (COVID-19) pneumonia.
- Trial name
- PRONE (NCT04517123)
- Testing
- Prone Positioning
- Where
- 4 sites in United States
- Volunteers
- 35 people
- Sponsor
- Johns Hopkins University
T Cell Deficiency
Functional Exhaustion of T Cells in COVID19 Patients
The primary end-point of our prospective, observational study is to count T cells in patients with laboratory-confirmed COVID-19 and healthy controls.
- Trial name
- NCT04470323
- Testing
- Flow cytometry
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Covid19
Comparison of Two Doses of Enoxaparin for Thromboprophylaxis in Hospitalized COVID-19 Patients
The purpose of this study is to determine whether a higher dose of low molecular weight heparin (enoxaparin 40 mg b.i.d.) is superior than the standard prophylaxis dose (enoxaparin 40 mg o.d.) in reducing thromboembolic events in…
- Trial name
- X-Covid 19 (NCT04366960)
- Testing
- Enoxaparin
- Where
- Italy
- Volunteers
- 189 people
- Sponsor
- Niguarda Hospital
Long COVID
Rehabilitation and Return to Everyday Life for Patients With Long COVID
This non-randomised controlled trial will investigate if patients with long COVID receiving a structured and group-based rehabilitation intervention (The Long COVID Rehabilitation Intervention) will report a difference in mean…
- Trial name
- NCT06544382
- Testing
- The Long COVID Rehabilitation Intervention, Usual care
- Where
- Denmark
- Volunteers
- 914 people
- Sponsor
- Defactum, Central Denmark Region
Tracheostomy
Timing of Tracheostomy in COVID-19 - Impact on Mortality
How timing of tracheostomy in COVID-19 patients changed and its impact on mortality in patients with severe COVID-19 ARDS
- Trial name
- NCT05175859
- Where
- Germany
- Volunteers
- 117 people
- Sponsor
- Goethe University
COVID-19
Prognosis of Geriatric Patients 1 Year After Hospitalization for COVID-19
Old patients hospitalized in Acute Geriatric Units are characterize by advanced age, frailty, high number of comorbidities, cognitive impairment and loss of functional autonomy.
- Trial name
- PROVID-Ger (NCT05261061)
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Invasive Fungal Infections
Open-label Study of APX001 for Treatment of Patients With Invasive Mold Infections Caused by Aspergillus or Rare Molds
This is a Phase 2, multicenter study to evaluate APX001 for the treatment of invasive fungal infections caused by Aspergillus spp. or rare molds (eg, Scedosporium spp., Fusarium spp., and Mucorales fungi).
- Trial name
- AEGIS (NCT04240886)
- Testing
- fosmanogepix
- Where
- 15 sites in United States, Belgium and 2 more
- Volunteers
- 21 people
- Sponsor
- Basilea Pharmaceutica
COVID-19, Healthy Volunteers
Executive Functioning and Sleep Fragmentation in COVID-19 Patients
This project aims to investigate executive functioning abilities (primary outcome) and quality of sleep (secondary outcome) in patients with COVID-19 (while distinguishing between those with and without sleep fragmentation)…
- Trial name
- NCT05764096
- Testing
- No intervention
- Where
- Italy
- Volunteers
- 76 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
COVID
Prevalence of Critical Forms of CoVid-19 in Patients With Chronic Respiratory Disease
A new Coronavirus (SARS-CoV-2) emerged in Wuhan Province, China in December 2019 and rapidly spread around the world. To date, the data in the literature regarding the clinical and epidemiological characteristics of severe forms…
- Trial name
- CRITICoVid (NCT04407169)
- Testing
- no intervention
- Where
- France
- Volunteers
- 617 people
- Sponsor
- Central Hospital, Nancy, France
Angina (Stable), INOCA (Ischemia With Non Obstructive Coronary Artery Disease)
Diagnostic and Clinical Management of Non-Obstructive Myocardial Ischemia in Patients With Long Covid-19 Syndrome and New Onset Chest Pain
Long Covid-19 INOCA is an investigator-initiated, prospective, randomized, sham-controlled, single center study. Its objective is to investigate the benefits of tailored medical therapy according to the results of the coronary…
- Conditions
- Angina (Stable), INOCA (Ischemia With Non Obstructive Coronary Artery Disease), Long COVID-19 Syndrome
- Trial name
- NCT07559994
- Testing
- Coronary functional test
- Where
- Spain
- Volunteers
- 108 people
- Sponsor
- Fundacion Investigacion Interhospitalaria Cardiovascular
COVID-19
Effect of Natural Food on Gut Microbiome and Phospholipid Spectrum of Immune Cells in COVID-19 Patients
The efficacy of natural foods such as freeze-dried mare's milk (Saumal) in post-COVID syndrome therapy has not been studied. The literature review has shown that researchers have focused more on evidence-based medications and…
- Trial name
- NCT05970861
- Testing
- Freeze-dried Mare Milk (Saumal)
- Where
- Kazakhstan
- Volunteers
- 75 people
- Sponsor
- Asfendiyarov Kazakh National Medical University
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