Clinical trials: Covid-19 Patients
SARS Virus
Prevalence and Risk Factors for Venous Thromboembolic Events in Critically Ill Patients With COVID-19
The purpose of the study is to assess the frequency of the occurrence of a venous thrombosis in patients with the new Coronavirus disease, who are admitted to the Intensive Care Unit for impending respiratory failure requiring…
- Trial name
- NCT04567927
- Testing
- Ultrasonography
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- Chiesa Alessandro Felice
Covid19, Outcome, Fatal
International Study of Inflammation in COVID-19
This is a prospective multi-center observational study which purpose is to evaluate the ability of blood-based inflammatory markers to risk-stratify patients hospitalized for Covid-19.
- Conditions
- Covid19, Outcome, Fatal, Respiratory Failure, Acute Kidney Injury
- Trial name
- ISIC (NCT04818866)
- Testing
- SuPAR, C-reactive protein, Ferritin, D-Dimer, Procalcitonin, Interleukin-6, Lactate Dehydrogenase
- Where
- United States
- Volunteers
- 4,463 people
- Sponsor
- University of Michigan
IgG4 Related Disease, Covid19
Impact of COVID-19 on the Clinical Outcomes and Management of IgG4 Related Disease Patients
Since December 2019, coronavirus disease 2019 (COVID-19), caused by the severe respiratory syndrome coronavirus 2 (SARS-CoV-2), has affected more than 124 million people worldwide as of 23/3/2021.
- Trial name
- IgG4-COVID (NCT04817553)
- Testing
- exposure to COVID19
- Where
- Hong Kong
- Volunteers
- 124 people
- Sponsor
- Chinese University of Hong Kong
Clinical Trial
Weight Loss in Patients With COVID-19 and Influenza in Comorbidity With NCDs: a Pilot Prospective Clinical Trial
The goal of this study was to evaluate the effects of the fast weight loss on clinic and laboratory inflammation profile, metabolic profile, reactive oxygen species (ROS) and body composition in patients with COVID and Influenza…
- Trial name
- NCT05635539
- Testing
- "Analimentary detoxication" (ANADETO) weight loss based on very-low-calorie-diet
- Where
- Kazakhstan
- Volunteers
- 62 people
- Sponsor
- University Medical Center, Kazakhstan
COVID-19 Patients
Hydroxychloroquine in Combination With Sirolimus and Dexamethasone for Treating COVID-19 Patients
COVID-19 caused an unprecedented international crisis. There is an urgent need for an effective regimen to cure this illness. Anecdotal data and some prospective results suggested a role of antimalarial drugs (chloroquine and…
- Trial name
- COVID19-HOPE (NCT04374903)
- Testing
- HCQ & AZ vs HCQ+SIR
- Where
- Jordan
- Sponsor
- King Hussein Cancer Center
Acute Lung Injury, ALI
A Study of RLS-0071 in Patients With Acute Lung Injury Due to COVID-19 Pneumonia in Early Respiratory Failure
The aim of this study will test the safety, tolerability, and efficacy of RLS-0071 for approximately 28 days in comparison to a placebo control in patients with acute lung injury due to COVID-19 pneumonia in early respiratory…
- Conditions
- Acute Lung Injury, ALI, COVID-19
- Trial name
- NCT04574869
- Testing
- RLS-0071 10 mg/kg, RLS-0071 40 mg/kg
- Where
- United States
- Sponsor
- ReAlta Life Sciences, Inc.
COVID-19
Exchange Transfusion Versus Plasma From Convalescent Patients With Methylene Blue in Patients With COVID-19
The aim of this project is to introduce way for treatment of patients with severe COVID-19 disease with respiratory complications.
- Trial name
- COVID-19 (NCT04376788)
- Testing
- exchange blood transfusion from normal donor, plasma from convalescent patients with COVID-19, Methylene Blue 5 MG/ML
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Ain Shams University
Covid19
Add on to Azythromycine, Phytomedicine and/or Antimalarial Drug vs Hydroxychloroquine in Uncomplicated COVID-19 Patients
The phase II clinical trial, with three arms and at rate of 10 patients per arm, received the approval of the National Committee for Ethics and Health Research.
- Trial name
- CANCOVID-19 (NCT04502342)
- Testing
- Hydroxycloroquine and Azythromycine, Cospherunate/Azythromycine, Cospherunate/Phytomedicine/Azythromycien
- Where
- Guinea
- Volunteers
- 30 people
- Sponsor
- Institute for Research and Development of Medicinal and Food Plants of Guinea
COVID-19
The Effect of Deep Breathing Exercise on Dyspnea, Anxiety and Quality of Life in Patients Treated for COVID-19
The world is facing an extremely important global epidemic. Coronavirus disease 2019 (COVID-19) epidemic, which first appeared in Wuhan, China in late 2019 and rapidly affected all countries of the world, was declared as a…
- Trial name
- NCT04696562
- Testing
- Deep Breathing Exercise with Triflo
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Ankara University
Liver Diseases
The Second COVID-19 Wave: Collateral Impact on Patients of Liver Disease
Hospital record of the patients of liver disease admitted from April-May 2021 and April-May 2019 will be reviewed. Patients will be analyzed and compared for the demographic characteristics, severity of liver disease at time of…
- Trial name
- NCT05167305
- Testing
- This is an observational study
- Where
- India
- Volunteers
- 1,316 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Covid19, Corona Virus Infection
Clinical Outcomes of High Dose Vitamin D Versus Standard Dose in COVID-19 Egyptian Patients
Vitamin D is a secosteroid hormone which may have beneficial role in reducing COVID-19 adverse outcomes by first regulating the renin angiotensin system (RAS).
- Conditions
- Covid19, Corona Virus Infection, Cytokine Storm, Vitamin D Deficiency
- Trial name
- NCT04738760
- Where
- Egypt
- Volunteers
- 116 people
- Sponsor
- Ain Shams University
Respiratory Disease
Screening Patients for a Strategic Shift to Pulmonary Telerehabilitation Because of COVID-19
This study applied the Pulmonary Rehabilitation Adapted Index of Self-Efficacy (PRAISE) on respiratory patients who had their on-going ambulatory Pulmonary Rehabilitation program interrupted due to the COVID-19 outbreak.
- Trial name
- PRAISE@COVID (NCT04388579)
- Testing
- Pulmonary Rehabilitation
- Where
- 3 sites in Portugal
- Volunteers
- 100 people
- Sponsor
- University of Lisbon
COVID
Therapeutic Vaccine Trial of COVID-19 for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection
GC004 is a Phase I trial to evaluate the safety and the immune responses of a therapeutic vaccine in SARS-CoV-2 infected patients.
- Trial name
- NCT04428073
- Testing
- Covax-19™
- Volunteers
- 32 people
- Sponsor
- GeneCure Biotechnologies
COVID-19, Muscle Atrophy
Electrical Stimulation for Critically Ill Post-Covid-19 Patients
Unfortunately, hospital-acquired weakness is highly prevalent among COVID-19 hospitalized patients, who often require prolonged bed-rest or paralytics for an extended period of time in order to maintain oxygenation.
- Conditions
- COVID-19, Muscle Atrophy, Muscle Weakness
- Trial name
- Phase II (NCT05198466)
- Testing
- Electrical Stimulation
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Baylor College of Medicine
Acute Hypoxemic Respiratory Failure
Efficacy of DEXamethasone in Patients With Acute Hypoxemic REspiratory Failure Caused by INfEctions
Background: There are no proven therapies specific for pulmonary dysfunction in patients with acute hypoxemic respiratory failure (AHRF) caused by infections (including Covid-19).
- Trial name
- DEXA-REFINE (NCT04545242)
- Testing
- Dexamethasone
- Where
- 40 sites in Spain
- Volunteers
- 980 people
- Sponsor
- Hospital Universitario de Gran Canaria Doctor Negrín
Covid19
A Phase III Confirmatory Study of K-237
The efficacy and safety of K-237 0.3-0.4 mg/kg orally administered once daily for 3 days will be evaluated in patients with mild COVID-19 using a randomized, double-blind, parallel-group comparative method with placebo as a…
- Trial name
- NCT05056883
- Testing
- K-237 0.3-0.4mg/kg (once daily)
- Where
- 55 sites in Japan, Thailand
- Volunteers
- 1,030 people
- Sponsor
- Kowa Company, Ltd.
Covid19, Critical Illness
Early Occupational Therapy in Mechanical Ventilated Patients With Covid-19
This study evaluates the feasibility of an early occupational therapy (OT) protocol in critical adult patients requiring mechanical ventilation with Covid-19.
- Conditions
- Covid19, Critical Illness, Impairment, Cognitive, Impairment, Coordination
- Trial name
- NCT04904497
- Testing
- Early Occupational Therapy
- Where
- Chile
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Chile
Pneumonia Due to COVID-19
Education Impact on Rehabilitation of Hospitalized Patients With Pneumonia and COVID-19
The planned research will enable the assessment of rehabilitation's effects using two pulmonary rehabilitation models: conventional and supplemented with an education program for patients hospitalized due to pneumonia with…
- Trial name
- NCT06522724
- Testing
- Education program, Pulmonary rehabilitation
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- University of Rzeszow
COVID-19
Predicting the Need for Intubation in Hospitalised COVID-19 Patients (PRED ICU COVID19)
One of the main challenges of the health crisis caused by the COVID-19 epidemic is the availability of beds in intensive care units (ICUs) and, more importantly, the need for invasive mechanical ventilation (IVM) because the ICUs…
- Trial name
- NCT04376879
- Testing
- Data monitoring for 48h within the first 24 hours of admission for COVID-19
- Where
- 2 sites in France
- Volunteers
- 301 people
- Sponsor
- Central Hospital, Nancy, France
Myasthenia Gravis
Follow-up of a Cohort of Patients With Myasthenic Syndrome and COVID-19 Infection
Coronavirus disease 2019 (COVID-19), declared by the World Health Organization (WHO) as a "public health emergency of international concern" (January 31, 2020), has posed a significant threat to global health.
- Trial name
- CO-MY-COVID (NCT04695379)
- Where
- 10 sites in France
- Volunteers
- 34 people
- Sponsor
- University Hospital, Bordeaux