Clinical trials: Covid-19 Patients
COVID-19
Registry of COVID-19 Patients Treated With the Seraph 100 Microbind Affinity Blood Filter
The purpose of this registry study is to investigate the effectiveness and safety of the Seraph® 100 Microbind® Affinity Blood Filter (Seraph 100) in the treatment of COVID-19 patients.
- Trial name
- COSA (NCT04361500)
- Testing
- Seraph 100
- Where
- 2 sites in Germany
- Volunteers
- 100 people
- Sponsor
- Hannover Medical School
Covid19, Respiratory Disease
Efficacy and Safety of Viusid and Asbrip in Hospitalized Patients With Mild and Moderate COVID-19
This is a two-arm, randomized, open label, two-center, controlled study to evaluate the safety and efficacy of Viusid plus Asbrip in patients with mild and moderate symptoms of respiratory illness caused by Coronavirus 2019…
- Conditions
- Covid19, Respiratory Disease, Immune System, Immunomodulator
- Trial name
- NCT04701502
- Testing
- Viusid, Asbrip, Standard Care
- Where
- 2 sites in Bulgaria
- Volunteers
- 60 people
- Sponsor
- Catalysis SL
COVID 19, Immunomediated Inflammatory Disease in Treatment With Biological Agents and / or Jak Inhibitors
Randomized, Controlled, Double-blind Clinical Trial Comparing the Efficacy and Safety of Chemoprophylaxis With Hydroxychloroquine in Patients Under Biological Treatment and / or JAK Inhibitors in the Prevention of SARS-CoV-2 Infection
The investigators plan to evaluate a strategy of chemoprophylaxis with hydroxyloquine (HCQ) against COVID-19 infection in patients diagnosed with an immunomediated inflammatory disease who are following a treatment with…
- Trial name
- NCT04330495
- Testing
- Hidroxicloroquina, Control group
- Sponsor
- Instituto de Investigación Marqués de Valdecilla
COVID-19 Pneumonia
Prognostic Value Of Chest Ultrasound (Lung Ultrasound Score) In COVID-19 Pneumonia Patients
This study aims to 1. To study the prognostic value of LUS in COVID-19 patients. 2. To assess the relation between Lung Ultrasonography Score and disease severity in COVID-19 Patients. 3.
- Trial name
- NCT05080257
- Testing
- Lung Ultrasonography
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
COVID, Severe Acute Respiratory Syndrome
LSALT Peptide vs. Placebo to Prevent ARDS and Acute Kidney Injury in Patients Infected With SARS-CoV-2 (COVID-19)
To evaluate the proportion of subjects alive and free of respiratory failure (e.g. need for non-invasive or invasive mechanical ventilation, high flow oxygen, or ECMO) and free of the need for continued renal replacement therapy…
- Conditions
- COVID, Severe Acute Respiratory Syndrome, Sars-CoV2, Acute Kidney Injury
- Trial name
- NCT04402957
- Testing
- LSALT peptide
- Where
- 7 sites in United States, Canada and 1 more
- Volunteers
- 61 people
- Sponsor
- Arch Biopartners Inc.
COVID-19 Infection
Double Blind Randomized Clinical Trial of Use of Colchicine Added to Standard Treatment in Hospitalized With Covid-19
EC CORONACOLCHI is a multicenter, double-blind and randomized clinical trial with two branches. Patients who meet all the inclusion criteria and none of the exclusion criteria will be randomized 1: 1 to be included in one of the…
- Trial name
- NCT04997551
- Testing
- Colchcine
- Where
- Spain
- Volunteers
- 752 people
- Sponsor
- Biogipuzkoa Health Research Institute
Dialysis; Complications, COVID-19
Immune Response Following COVID-19 in Hemodialysis Patients
Patients with chronic kidney disease (CKD), particularly those undergoing hemodialysis (HD), are at high risk of a severe form of COVID-19.
- Conditions
- Dialysis; Complications, COVID-19, Cytokine Storm
- Trial name
- IMMUNOVIDIAL (NCT05307601)
- Where
- France
- Volunteers
- 21 people
- Sponsor
- AURA Paris
Chronic Heart Failure, Chronic Kidney Diseases
ODYSSEE-vCHAT Mental Health Program for Heart Failure and Kidney Disease Patients
INTRODUCTION Psychological distress and reduced quality of life are prevalent in patients with chronic heart failure (CHF) and advanced chronic kidney disease (CKD).
- Trial name
- ODYSSEEvCHAT (NCT05560737)
- Testing
- ODYSSEE-vCHAT
- Where
- 4 sites in Canada
- Volunteers
- 215 people
- Sponsor
- University Health Network, Toronto
COVID-19
Efficacy and Safety of Ambervin® and Standard Therapy in Hospitalized Patients With COVID-19
This is open-labe randomized multicenter comparative Phase III study conducted in 8 medical facilities. The objective of the study is to assess the efficacy, safety and tolerability of Ambervin for intramuscular and inhaled…
- Trial name
- NCT05656495
- Testing
- Tyrosyl-D-alanyl-glycyl-phenylalanyl-leucyl-arginine succinate intramuscularly, Tyrosyl-D-alanyl-glycyl-phenylalanyl-leucyl-arginine succinate inhaled, Standard of care
- Where
- 10 sites in Russia
- Volunteers
- 313 people
- Sponsor
- Promomed, LLC
COVID-19
Investigation of the Muscle Oxygenation in Patients With Post COVID-19 Syndrome
More than 60% of patients infected with COVID-19 have long-term symptoms. These symptoms are associated with common ground-glass opacities on computed tomography scans and chest radiographs.
- Trial name
- NCT05957575
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Gazi University
COVID-19 Patients
Independent Predictors on Clinical Outcomes in SARS-CoV2 Patients
The clinical spectrum of COVID-19 can be very heterogeneous: from mild flu-like symptoms, to the form with severe pulmonary impairment (dyspnoea, tachypnoea, PaO2 / FiO2 ratio below 300 at arterial blood gas sampling, pulmonary…
- Trial name
- outcomes (NCT05162534)
- Testing
- effect of COVID-19 exposure
- Where
- Italy
- Volunteers
- 1,800 people
- Sponsor
- University Hospital of Ferrara
Respiratory Distress Syndrome, Adult
A Clinical Trial to Evaluate the Safety of agenT-797 in COVID-19 Participants With ARDS
A Phase 1 study of agenT-797 to treat moderate to severe acute respiratory syndrome in Coronavirus disease 2019 (COVID-19) participants.
- Trial name
- NCT04582201
- Testing
- agenT-797
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- MiNK Therapeutics
Long COVID, Experience, Life
Living With Long COVID: LONGCOVID-EXPERIENCE
Background: One in ten people infected with COVID-19 presents persistent COVID, which consists of the presence of symptoms three months after the acute manifestations of COVID-19 and their persistence for at least two months…
- Trial name
- NCT06118112
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Corporacion Parc Tauli
COVID-19 (Coronavirus Disease 2019)
Thrombohemorrhagic Complications of COVID-19
The nature of the planned study: The topic is of an applied nature and is aimed at improving the results of comprehensive treatment of patients with COVID-19, the course of whose disease was complicated by thrombotic or…
- Trial name
- NCT06223945
- Testing
- Prevention algorithm
- Where
- Russia
- Volunteers
- 1 people
- Sponsor
- Volgograd State Medical University
Corona Virus Infection, Acute Respiratory Distress Syndrome
Losartan for Patients With COVID-19 Not Requiring Hospitalization
This is a multi-center, double-blinded study of COVID-19 infected patients randomized 1:1 to daily losartan or placebo for 10 days or treatment failure (hospital admission).
- Conditions
- Corona Virus Infection, Acute Respiratory Distress Syndrome, SARS-CoV Infection
- Trial name
- NCT04311177
- Testing
- Losartan
- Where
- 4 sites in United States
- Volunteers
- 117 people
- Sponsor
- University of Minnesota
Malignancies Multiple
Coronavirus Disease 2019 (COVID-19) Vaccination in Cancer Patients
The current study primarily aims to determine the status of vaccination in enrolled cancer patients and identify barriers to coronavirus disease 2019 (COVID-19) vaccination in cancer patients who have not been vaccinated.
- Trial name
- NCT04953065
- Testing
- COVID-19 vaccine hesitancy and acceptance survey
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Monika Joshi
Colorectal Cancer, Nursing
The Effect of a Mobile Application on Patient Outcomes in Colorectal Cancer Patients
The aim of this study is to determine the effect of the interactive nurse support program developed as a mobile application on patient outcomes (symptom management, quality of life, perception of social support and anxiety) in…
- Trial name
- NCT05813028
- Testing
- a Mobile Application
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ankara University
Covid19
Is Bio-adrenomedullin (Bio-ADM) a Prognostic Factor in Patients With COVID-19 Treated in the ICU?
This is prospective, observational study using point of care test to determine bio-ADM whole blood concentrations and its predictive value in patients with COVID-19 treated in the ICU.
- Trial name
- NCT04813939
- Testing
- IB10 sphingotest® bio-ADM® apparatus (Sphingotec GmbH, Hennigsdorf, Germany)
- Where
- Poland
- Volunteers
- 32 people
- Sponsor
- Medical University of Warsaw
Covid19
The RAPID COVID Study - Application of Point-of-Care COVID-19 Testing
This study is being conducted to study the use and application of a point-of-care (POC) Covid-19 test developed by Spartan BioSciences and recently approved for clinical use by Health Canada.
- Trial name
- RAPID COVID (NCT04767958)
- Testing
- Spartan COVID-19 Platform
- Where
- Canada
- Volunteers
- 89 people
- Sponsor
- Ottawa Heart Institute Research Corporation
COVID-19, Severe Acute Respiratory Syndrome
Hydroxychloroquine Chemoprophylaxis in Healthcare Personnel in Contact With COVID-19 Patients (PHYDRA Trial)
Triple blinded, phase III randomized controlled trial with parallel groups (200mg of hydroxychloroquine per day vs. placebo) aiming to prove hydroxychloroquine's security and efficacy as prophylaxis treatment for healthcare…
- Trial name
- PHYDRA (NCT04318015)
- Testing
- Hydroxychloroquine
- Where
- Mexico
- Volunteers
- 289 people, healthy volunteers welcome
- Sponsor
- National Institute of Respiratory Diseases, Mexico
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