Clinical trials: Covid-19 Patients
COVID
Ivermectin in Treatment of COVID-19
confirmed cases with COVID-19 will receive ivermectin as a therapeutic option as well as standard of care treatment and will be compared to those that will receive only standard of care ttt
- Trial name
- NCT04445311
- Testing
- Ivermectin
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Zagazig University
Covid19
Oral Camostat Compared With Standard Supportive Care in Mild-Moderate COVID-19 Patients
This study will evaluate the efficacy of oral Foipan® (camostat mesilate) compared with the current standard of care in reducing the duration of viral shedding of SARS-CoV-2 virus in patients with mild-moderate COVID-19 disease.
- Trial name
- COPS-2003 (NCT04524663)
- Testing
- Camostat Mesilate, Standard of Care Treatment
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Stanford University
Acute Respiratory Distress Syndrome
Safety and Efficacy of Intravenous Wharton's Jelly Derived Mesenchymal Stem Cells in Acute Respiratory Distress Syndrome Due to COVID 19
Recent COVID 19 pandemic has overwhelmed health services all around the world, and humanity has yet to find a cure or a vaccine for the treatment of patients, mainly the severe ones, who pose a therapeutic challenge to healthcare…
- Trial name
- NCT04390152
- Testing
- Wharton's jelly derived Mesenchymal stem cells.
- Where
- 2 sites in Colombia
- Volunteers
- 6 people
- Sponsor
- BioXcellerator
Acute Respiratory Distress Syndrome, Coronavirus Infection
Vadadustat for the Prevention and Treatment of Acute Respiratory Distress Syndrome (ARDS) in Hospitalized Patients With Coronavirus Disease 2019 (COVID-19)
The purpose of this study is to evaluate the efficacy of vadadustat for the prevention and treatment of acute respiratory distress syndrome (ARDS) in hospitalized patients with Coronavirus Disease 2019 (COVID-19).
- Trial name
- NCT04478071
- Testing
- vadadustat
- Where
- United States
- Volunteers
- 448 people
- Sponsor
- The University of Texas Health Science Center, Houston
Treatment of Covid-19 Virus Infection
Effect of a Combination of Treatment of Reginmune Capsule and Immunofree Tablets in the Treatment of Mild to Moderate COVID-19 Patients
While novel drug discovery and vaccine studies are time taking process, re-purposing old drugs against the COVID-2019 epidemic can help identify treatments, with known pre-clinical, pharmacokinetic, pharmacodynamic, and toxicity…
- Trial name
- NCT04494204
- Testing
- Immunofree tablets and Reginmune capsule
- Where
- 3 sites in India
- Volunteers
- 100 people
- Sponsor
- PUNEET MITTAL
Cognition, Covid-19
Neurocognitive Functions of Recovered COVID-19 Patients
This study is carried on in Wuchang Hospital in Wuhan, China. The investigators plan to recruit 80 patients with COVID-19 and 80 matched healthy control.
- Trial name
- NCT04622748
- Testing
- Trier Social Stress Test
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Dependence, China
COVID, Terminal Renal Insufficiency
Antibody Response Against SARS-CoV-2 in Dialysis Patients During COVID-19
Determination of IgM and IgG antibodies against SARS-CoV-2 in dialysis patients by continous monitoring in the period from March 2020 to december 2020
- Trial name
- COVCKD (NCT04367714)
- Where
- Denmark
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Region MidtJylland Denmark
Covid19, Infective Pneumonia
The Effect of Inspiratory Muscle Training in Post COVID-19 Patients
The COVID-19 infection, which is considered as a pandemic by the World Health Organization, affects the whole world. COVID-19 is an infectious respiratory disease caused by SARS-CoV-2.
- Trial name
- NCT04811859
- Testing
- Inspiratory Muscle Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istinye University
COVID-19
Nasal Epithelial Genetic and Single Cell RNA COVID-19 Study
Rationale: The investigators hypothesize that genetics and the nasal epithelial response to SARS-CoV2 are critical determinants of the immune response to viral infection, and predict clinical outcome in COVID-19 patients.
- Trial name
- CIPOLLINI (NCT04359459)
- Sponsor
- University Medical Center Groningen
COVID-19
Part Two of Novel Adoptive Cellular Therapy With SARS-CoV-2 Specific T Cells in Patients With Severe COVID-19
The overall objective of this project is to develop an emergent treatment protocol using adoptive T-cell therapy for the treatment of severe COVID-19.
- Trial name
- NCT04457726
- Testing
- SARS-CoV-2 Specific T Cells
- Where
- 5 sites in Singapore
- Volunteers
- 18 people
- Sponsor
- KK Women's and Children's Hospital
Laboratory Assessment SARS-CoV-2 Antibody Levels Before and After Surgery for Patients Requiring Cardiopulmonary Bypass
Quantitative COVID-19 SARS-CoV-2 Antibody Pre and Post Cardiopulmonary Bypass
This study is designed to compare the levels of SARS-CoV-2 antibody prior to cardiopulmonary bypass and after cardiopulmonary bypass (CPB).
- Trial name
- NCT05357885
- Testing
- SARS-CoV-2 Antibody test
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Thomas Jefferson University
Kidney Transplant, Pancreas Tranplant
Observational Study Concerning COVID-19 Infection in Transplanted Kidney, Pancreas or Pancreatic Islet Patients
Collect informations on the health status of transplanted patients (kidney, kidney / pancreas, pancreas or pancreatic islet) during the COVID-19 pandemic. All informations will be collected by short questionnaire via phone.
- Conditions
- Kidney Transplant, Pancreas Tranplant, Pancreatic Islet Transplantation
- Trial name
- NCT04377776
- Testing
- Practice details
- Where
- Italy
- Volunteers
- 644 people
- Sponsor
- IRCCS San Raffaele
Tension-Type Headache, Orofacial Pain
Laser Therapy on Tension-type Cephalea and Orofacial Pain in Post-covid-19 Patients
Considering the auxiliary potential effect of photobiomodulation in controlling persistent CTT and TMD-related pain in patients who have been diagnosed with COVID-19, and are recovered from the viral infection, we intend to…
- Conditions
- Tension-Type Headache, Orofacial Pain, COVID-19
- Trial name
- NCT05430776
- Testing
- Photobimodulation
- Where
- 2 sites in Brazil
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Covid-19, Anosmia
Brain MRI Imaging in Patients With SARS-Cov2 (COVID-19) Infection With or Without Anosmia
To date there is no brain imaging and olfactory data available in COVID-19 positive patients with anosmia. By describing the pathophysiological characteristics underlying the olfactory symptoms and clinical characteristics of…
- Trial name
- ANOSIRM (NCT04408391)
- Testing
- Brain MRI scan
- Where
- France
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Coronavirus
Eculizumab (Soliris) in Covid-19 Infected Patients
Covid-19 has spread rapidly throughout the world causing widespread panic, death, and injury. While this virus is the provocateur, it is often the patient's own disproportionate immune response which deals the most devastating…
- Trial name
- SOLID-C19 (NCT04288713)
- Testing
- Eculizumab
- Sponsor
- Hudson Medical
COVID-19
Epidemiological Analysis of Ambulant Patients in a COVID-19 Outpatient Clinic
There is insufficient knowledge about transmission routes and the effectiveness of general protective measures to prevent infection, such as the closure of schools or the wearing of mouthguards.
- Trial name
- NCT04521088
- Where
- Germany
- Volunteers
- 1,316 people
- Sponsor
- Wissenschaftliches Institut Bethanien e.V
COVID 19
Sensor Based Vital Signs Monitoring of Covid 19 Patients During Home Isolation
Severe acute respiratory syndrome (SARS) SARS-Cov-2 disease (COVID-19) is an infectious disease caused by a coronavirus. The pandemic first described in Wuhan, China, has since spread across the whole world and caused dramatic…
- Trial name
- HSC19 (NCT04335097)
- Testing
- Biosensors
- Where
- Norway
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Lars Wik
Covid19, Angiotensin II Receptor Antagonist Adverse Reaction
Switch of Renin-Angiotensin System Inhibitors in Patients With Covid-19
The SWITCH-COVID trial will randomize patients with COVID-19 that are currently using renin-angiotensin system inhibitors for treating hypertension to maintain the therapy during in-hospital stay or switch the therapy to other…
- Trial name
- SWITCH-COVID (NCT04493359)
- Testing
- Renin-angiotensin system inhibitors
- Where
- Brazil
- Volunteers
- 18 people
- Sponsor
- University of Sao Paulo
Covid19
HSD3B1 Gene Polymorphisms With Outcomes in SARS-CoV-2 Infected Patients
The study includes 2 sub-projects. Sub-project 1: The aim is to evaluate the expression of receptors and activating proteases mediating SARS-CoV-2 entry and spreading in the local population of Ticino.
- Trial name
- NCT04516850
- Testing
- Expression of receptors and activating proteases, Polymorphism of the HSD3B1
- Where
- 2 sites in Switzerland
- Volunteers
- 400 people
- Sponsor
- Ricardo Pereira Mestre
Cardiovascular Diseases, Cardiovascular Risk Factor
Characterization of Cardiovascular Diseases and Risk Factors in Patients With Suspected SARS-CoV2/Covid-19 Infection
The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infects host-cells via ACE2-receptors, which leads to pneumonia (COVID-19) but also can lead to myocarditis (acute myocardial injury) and chronic damage to the…
- Conditions
- Cardiovascular Diseases, Cardiovascular Risk Factor, SARS
- Trial name
- NCT04327479
- Testing
- Assessment of cardiovascular diseases and cardiovascular risk factors
- Where
- Germany
- Volunteers
- 728 people
- Sponsor
- University Hospital, Essen
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