Clinical trials: Covid-19 Patients
COVID, Sars-CoV2
Experimental Expanded Access Treatment With Convalescent Plasma for the Treatment of Patients With COVID-19
The purpose of this program is to see if giving convalescent plasma to individuals who test positive for COVID-19 may reduce their symptoms and help minimize complications from the illness.
- Conditions
- COVID, Sars-CoV2, Corona Virus Infection
- Trial name
- NCT04445207
- Testing
- Convalescent Plasma
- Where
- United States
- Sponsor
- Jonathan Gerber
COVID-19 Pandemic
RCT on the Efficacy of Dexamethasone Versus Methyl Prednisolone in Covid-19 Infected Patients With High Oxygen Flow
This study aims to evaluate the therapeutic activity and side effects of 16 mg/day dexamethasone in comparison to equivalent dose of MP (1mg/kg/day)for the management of COVID-19 infected patients.Moreover, and according to the…
- Trial name
- NCT05062681
- Testing
- Dexamethasone, Methylprednisolone
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Covid19, Diabetes Mellitus
Incidence and Predictors of Acute and Chronic Complications in Patients With Diabetes and Severe COVID-19
All surviving patients of the Michigan Medicine COVID-19 Cohort (M2C2, PI: Hayek) that were admitted to the University of Michigan for severe COVID-19 disease are eligible for this study.
- Trial name
- NCT05200819
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Michigan
Covid-19 Pneumonia
Reliability of a Pocket Sized Ultrasound Scanner in the Evaluation Covid-19 Pneumonia
Ultrasound imaging of the lung (LUS) and associated tissues has demonstrated clinical utility in COVID-19 patients. The aim of the present study was to evaluate the possibilities of a portable pocket-sized ultrasound scanner in…
- Trial name
- USCovid (NCT04433000)
- Testing
- Butterfly
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- University of Siena
Covid19
Estetrol (E4) for the Treatment of Patients With Confirmed SARS-COV-2 Infection
It has been reported in several research studies that men are almost twice as likely to progress to severe COVID 19 disease and die than women.
- Trial name
- NCT04801836
- Testing
- Estetrol monohydrate 15 mg
- Where
- 25 sites in Belgium, Hungary and 2 more
- Volunteers
- 162 people
- Sponsor
- NEURALIS s.a.
Diabetic Foot Ulcer
Use of Remote Thermovisual Monitoring in Patients With a Previous Diabetic Foot Ulcer
The goal of the clinical trial is to investigate adherence to, and effects of, the Bluedrop Monitoring System (BMS) in high-risk patients with at least one previous diabetic foot ulcer (DFU).
- Trial name
- NCT05039645
- Testing
- Patient specific, clinician determined Intervention
- Where
- 2 sites in Ireland, United Kingdom
- Volunteers
- 31 people
- Sponsor
- Bluedrop Medical Limited
COVID-19, Sars-CoV2
Effects of COVID-19 Convalescent Plasma (CCP) on Coronavirus-associated Complications in Hospitalized Patients
The purpose of this study assess the efficacy and safety of anti-SARS-CoV-2 convalescent plasma in hospitalized patients with acute respiratory symptoms up to 14 days after the onset of initial symptoms.
- Trial name
- CAPRI (NCT04421404)
- Testing
- COVID-19 Convalescent Plasma (CCP)
- Where
- 3 sites in United States
- Volunteers
- 34 people
- Sponsor
- Priscilla Hsue, MD
COPD, COVID-19
Impact of COVID-19 on Lung Function in COPD Patients.
Background: In 2019, a novel coronavirus (SARS-COV2) was detected in Wuhan, China as a cause of acute respiratory distress syndrome (COVID-19).
- Trial name
- EspirCOVID (NCT05770440)
- Where
- Spain
- Volunteers
- 250 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
COVID-19
Sleep Quality and Quality of Life in Coronavirus 19 Disease ( COVID 19) Patients
To study the impact of COVID 19 infection on sleep habit as regards quality of sleep, emergence of insomnia. To assess quality of life in patients after COVID 19 infection.
- Trial name
- NCT05148858
- Volunteers
- 100 people
- Sponsor
- Assiut University
COVID19
Trial to Study the Benefit of Colchicine in Patients With COVID-19
COVID-19 is associated with a cytokine storm that leads to respiratory distress, multiorgan failure and elevated mortality. Oral colchicine exhibits high anti-inflammatory capacity attributed to the inhibition of microtubules…
- Trial name
- COL-COVID (NCT04350320)
- Testing
- Colchicine Tablets, Standard therapy for COVID-19 according to the stablished hospital protocols.
- Where
- Spain
- Volunteers
- 102 people
- Sponsor
- Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia
COVID-19, Acute Respiratory Failure
High Flow Nasal Cannula Versus High Velocity Nasal Insufflation in Covid-19
To compare the outcomes of HFNC and HVNI in COVID-19 patients with acute respiratory failure as regard need for mechanical ventilation, changes of arterial blood gases (ABG) parameters, duration of ventilatory support and delay…
- Trial name
- NCT05216640
- Testing
- High Flow Oxygen Therapy
- Volunteers
- 50 people
- Sponsor
- Assiut University
COVID-19 Infections
Glucocorticoid Therapy for COVID-19 Critically Ill Patients With Severe Acute Respiratory Failure
In this multi-center, randomized, control study, the investigators will evaluate the efficacy and safety of glucocorticoid in combination with standard care for COVID-19 patents with Severe acute respiratory failure.
- Trial name
- NCT04244591
- Testing
- methylprednisolone therapy, Standard care
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Peking Union Medical College Hospital
Post-COVID-19
Sleep Characteristics in Post-COVID-19 Patients
After acute infection, patients with coronavirus disease 2019 (COVID-19) often suffer from persisting symptoms for more than 3 months (post COVID-19).
- Trial name
- NCT05124548
- Testing
- Sleep diagnostics
- Where
- Germany
- Volunteers
- 31 people
- Sponsor
- Schön Klinik Berchtesgadener Land
Lung Function, Exercise Capacity
Lung Function, Exercise Capacity, and Serology Responses in Patients With COVID-19
(a) Objectives 1. To assess the full lung function, exercise capacity, quality of life in patients with COVID-19 over 2 years. 2. To assess the longevity of the serology response to SARS-CoV2. 3.
- Conditions
- Lung Function, Exercise Capacity, Quality of Life, Covid19
- Trial name
- NCT04611243
- Testing
- third dose vaccination with CoronaVac vaccine, third dose vaccination with BionTech vaccine, Vaccination with Coronavac vaccine
- Where
- Hong Kong
- Volunteers
- 700 people
- Sponsor
- Chinese University of Hong Kong
COVID-19, SARS-CoV-2
PEP Flute-selfcare in COVID-19
Most research on the coronavirus SARS-CoV-2 and COVID-19 disease relate to screening measures, development of vaccines and optimising treatment of hospitalised patients.
- Trial name
- PEP-CoV (NCT04530435)
- Testing
- PEP flute
- Where
- Denmark
- Volunteers
- 378 people
- Sponsor
- Bispebjerg Hospital
Patient Engagement, COVID-19
Collaborative Open Research Initiative Study (CORIS-1)
The Collaborative Open Research Initiative Study (CORIS) is a groundbreaking international research endeavor aimed at exploring vital topics within the field of health professions education.
- Conditions
- Patient Engagement, COVID-19, Preventable Disease, Vaccine, Burnout, Professional
- Trial name
- CORIS-1 (NCT06357650)
- Testing
- No intervention. This is an observational study
- Volunteers
- 15,000 people
- Sponsor
- Chisquares Incorporated
ARDS, Covid19
Evaluating AVM0703 for Treatment of COVID-19 or Influenza-mediated ARDS
This is a randomized, double-blinded, placebo-controlled study of AVM0703 administered as a single intravenous (IV) infusion to patients with moderate or severe immediately life-threatening Acute Respiratory Distress Syndrome…
- Conditions
- ARDS, Covid19, Influenza, Human
- Trial name
- AVM0703 (NCT04366115)
- Testing
- AVM0703
- Volunteers
- 16 people
- Sponsor
- AVM Biotechnology Inc
COVID-19 Pandemic
Use of Artificial Intelligence (AI) to Predict Clinical Outcomes in Patients Hospitalized for COVID19 Pneumonia During the 4 Pandemic Waves
Predictive models can be applied in different areas, during the emergency of the COVID-19 pandemic, in fact, they have proven important in supporting health systems in planning strategic decisions and in formulating health…
- Trial name
- AI COVID-19 (NCT06424925)
- Testing
- Artificial intelligence for the prediction of clinical outcomes
- Where
- Italy
- Volunteers
- 5,000 people
- Sponsor
- Azienda Ospedaliera di Lecco
Covid-19, Critical Illness
Prospective Observational Cohort Study of Critically Ill Patients With Covid-19 in Sweden
The study will prospectively collect data from patients with Covid-19 admitted to the Västerås Intensive Care Unit, Västerås Hospital. Demographic, clinical, radiographic and laboratory characteristics will be recorded.
- Trial name
- NCT04382417
- Testing
- Observational study
- Where
- Sweden
- Volunteers
- 57 people
- Sponsor
- Region Västmanland
Covid19
Safety and Efficacy of Intranasal Application of GX-03 as a Treatment and Prevention for COVID-19.
Phase 2b clinical trial to evaluate the safety and efficacy of intranasal application of GX-03 as a treatment and prevention for COVID-19.
- Trial name
- NCT04951349
- Testing
- GX-03, Petrolatum ointment
- Where
- 3 sites in Panama
- Volunteers
- 85 people
- Sponsor
- Turn Therapeutics