Clinical trials: Covid-19 Patients
COVID-19, Post-COVID-19 Syndrome
Retinal Neurovascular Coupling in Patients Previously Infected With COVID-19
The Study objective is to measure retinal neurovascular coupling and blood flow parameters in patients previously infected with COVID-19, long COVID-19 and healthy age- and sex- matched control subjects
- Trial name
- NCT05650905
- Testing
- Dynamic Vessel Analyzer (DVA), Fourier domain optical coherence tomography (FDOCT), Optical coherence tomography (OCT)
- Where
- Austria
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
COVID-19
A Phase 1/2 Study to Assess Safety and Efficacy of BAT2020 in Hospitalized COVID-19 Patients
This is a randomized study to assess safety, pharmacokinetics, immunogenicity, and efficacy of BAT2020 in hospitalized patients infected with COVID-19.
- Trial name
- NCT04432766
- Testing
- BAT2020
- Where
- United States
- Sponsor
- Bio-Thera Solutions
COVID-19
Clinical Study for the Efficacy and Safety of Ropeginterferon Alfa-2b in Moderate COVID19.
To evaluate the efficacy of subcutaneous ropeginterferon alfa 2b ( P1101combined with standard of care (SOC) compared with standard care alone in hospitalized adults with moderate COVID 19.
- Trial name
- NCT05770466
- Testing
- P1101 (Ropeginterferon alfa-2b), SOC
- Where
- Taiwan
- Volunteers
- 134 people
- Sponsor
- National Taiwan University Hospital
Long COVID-19 Syndrome, Long COVID Symptoms
Epigenetic Changes in Long COVID Patients
The goal of this observational study is to improve the understanding of the biological mechanisms underlying long COVID and to identify molecular biomarkers that may support its diagnosis, prognosis, and future precision medicine…
- Trial name
- ECLIPSE (NCT07757620)
- Where
- 3 sites in Italy
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
COVID-19, Stress Disorders, Post-Traumatic
Psychological Impact of Medical Evacuations on Families of Patients Admitted to Intensive Care Unit for Severe COVID-19
At the "Métropole Savoie" hospital, to deal with the daily influx of severe patients during the second wave of COVID-19, 23 patients had to be transferred away from their home city and far from their families as part of a medical…
- Trial name
- IPES-CoV (NCT05421182)
- Testing
- Revised Impact of Event Scale, Hospital Anxiety and Depression scale, 36-Item Short Form Survey
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Metropole Savoie
COVID-19, Pneumonia, Viral
Checkpoint Blockade in COVID-19 Pandemic
This is a prospective, multicenter, randomized, controlled, open-label, phase 2 clinical trial
- Trial name
- COPERNICO (NCT04335305)
- Testing
- Tocilizumab, Pembrolizumab (MK-3475)
- Where
- 7 sites in Spain
- Volunteers
- 12 people
- Sponsor
- MedSIR
COVID-19, Rheumatoid Arthritis
COVID-SErology in Rheumatoid Arthritis (COVID-19)
Due to the Covid-19 worldwide outbreak, fragile patients with immune diseases, notably rheumatoid arthritis (RA), have to be even more specifically and carefully followed-up.
- Trial name
- COVID-SERA (NCT04407559)
- Testing
- Serological analyses to be lead on a pre-existing biobank
- Where
- France
- Volunteers
- 216 people
- Sponsor
- University Hospital, Montpellier
Respiratory Disease
Screening Patients for a Strategic Shift to Pulmonary Telerehabilitation Because of COVID-19
This study applied the Pulmonary Rehabilitation Adapted Index of Self-Efficacy (PRAISE) on respiratory patients who had their on-going ambulatory Pulmonary Rehabilitation program interrupted due to the COVID-19 outbreak.
- Trial name
- PRAISE@COVID (NCT04388579)
- Testing
- Pulmonary Rehabilitation
- Where
- 3 sites in Portugal
- Volunteers
- 100 people
- Sponsor
- University of Lisbon
SARS-CoV-2 Infection
Microvascular Injury and Distal Thrombosis in COVID-19
Investigators aimed to better understand the pathophysiology of SARS-CoV-2 pneumonia in non-critically ill hospitalized patients secondarily presenting with clinical deterioration and increase in oxygen requirement
- Trial name
- MIND (NCT04990505)
- Testing
- lung ventilation/perfusion scintigraphy
- Where
- Monaco
- Volunteers
- 25 people
- Sponsor
- Centre Hospitalier Princesse Grace
Corona Virus Infection
Impact of Colchicine in Hospitalized Colombian Patients With COVID-19
This is a phase IIIa, prospective, open-label, randomized, parallel-group study designed to evaluate the efficacy and safety of oral colchicine plus standard therapy versus standard therapy in the clinical course of SARS-CoV-2…
- Trial name
- (COLCOVID19) (NCT04539873)
- Testing
- Colchicine 0.5 MG, CONTROL GROUP
- Where
- Colombia
- Volunteers
- 128 people
- Sponsor
- Fundación Universitaria de Ciencias de la Salud
Covid19
Role of the Microbiota in the Evolution of the SARS-CoV-2 Disease,COVID-19, in Hospitalized Patients
Patients hospitalized for COVID-19 may need intensive care (e.g. mechanical ventilation) during hospitalization. Some risk factors are already known but better targeting of such patients is still needed, at least because existing…
- Trial name
- MicrobioCOVID (NCT04669938)
- Testing
- oropharyngeal and intestinal microbiota, host genotype, host immune factors
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
COVID, Acute Respiratory Failure
AKI Biomarkers in Coronavirus(COVID)-19
This research aims to investigate the role of daily measurement of urinary cell cycle arrest markers and other serum and urinary biomarkers to predict the development of acute kidney injury in critically ill patients with…
- Conditions
- COVID, Acute Respiratory Failure, Acute Kidney Injury
- Trial name
- NCT04408248
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Covid19
The Use of Brazilian Green Propolis Extract (EPP-AF) in Patients Affected by COVID-19.
The COVID-19 pandemic is of grave concern due its impact on human health and on the economy. Propolis, a natural resin produced by bees from plant materials, has anti-inflammatory, immunomodulatory, anti-oxidant properties, and…
- Trial name
- Bee-Covid (NCT04480593)
- Testing
- Brazilian Green Propolis Extract (EPP-AF), Standard care
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- D'Or Institute for Research and Education
Covid19
Estimation of Dynamics of Humoral and Cellular Immunity in COVID-19 Patients
The goal of the project: to study the dynamics of the humoral and cellular immunity in patients after pneumonia caused by the SARS-CoV-2 virus at different time intervals, in order to predict the duration of immune protection
- Trial name
- NCT04649840
- Testing
- Humoral and cellular immunity
- Where
- Belarus
- Volunteers
- 274 people
- Sponsor
- Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus
Alzheimer Disease, Telerehabilitation
Comparison of the Effect of Online Physical Exercise and Computerized Cognitive Stimulation in Patients With Alzheimer's Disease
Our aim has been determined to investigate the effect of physical exercise alone and in combination with cognitive exercise, on cognitive, physical function and quality of life in individuals with Alzheimer's Disease during the…
- Conditions
- Alzheimer Disease, Telerehabilitation, Online Physical Exercise, Computerized Cognitive Stimulation
- Trial name
- NCT04842734
- Testing
- Physical exercise, Physical exercise and computerized cognitive training
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Yeditepe University
Covid19, Left Ventricular Dysfunction
Cardiac Dysfunction in Critically Ill Patients With COVID-19
Cardiac dysfunction has been reported to be common in patients infected with COVID-19. The aim of this study is to evaluate the clinical importance of cardiac dysfunction in critically ill patients infected with COVID-19.
- Conditions
- Covid19, Left Ventricular Dysfunction, Right Ventricular Dysfunction, Pulmonary Hypertension
- Trial name
- CARDYCOVID (NCT04524234)
- Testing
- Echocardiography
- Where
- 5 sites in Sweden
- Volunteers
- 132 people
- Sponsor
- Sahlgrenska University Hospital
COVID-19, SARS-CoV2 Infection
COVID Card Pilot Study to Detect Antibodies to SARS-CoV-2
This study aims to investigate the clinical performance characteristics of the novel point-of-care, semi-quantitative test for SARS-CoV-2 in the Emergency Department compared to the gold standard (ELISA).
- Trial name
- NCT05196932
- Testing
- Novel point-of-care, semi-quantitative test for SARS-CoV-2 antibodies
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
SARS-CoV-2 Infection
Real World Evaluation of the Effectiveness of AZD7442 for Prevention of SARS-CoV-2
If a treated cancer patient cannot make antibodies to a Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Emergency Use Authorization (EUA) or approved vaccine, their risk for infection and its sequelae are…
- Trial name
- NCT05438498
- Testing
- Evusheld (tixagevimab+cilgavimab) IM or IV
- Where
- 40 sites in United States
- Volunteers
- 550 people
- Sponsor
- MediMergent, LLC
COVID-19
Pilot Test of COVID-19 Related Clinical Outcome Assessment Methodology and Qualitative Evidence of Content Validity
COVID-19 is an acute respiratory disease caused by Severe Acute Respiratory Syndrome coronavirus (SARS-CoV). Synairgen is currently conducting a global Phase III clinical trial of SNG001 to determine efficacy and safety in…
- Trial name
- NCT05207293
- Where
- 5 sites in United States, United Kingdom
- Volunteers
- 29 people
- Sponsor
- Synairgen Research Ltd.
COVID-19 Pneumonia, Viral Pneumonia
Mesenchymal Stromal Cells for COVID-19 and Viral Pneumonias
This is an open-label phase 1 clinical trial of allogeneic umbilical cord derived mesenchymal stromal cells (MSCs) for hospitalized individuals with COVID-19 or other viral pneumonias.
- Trial name
- SAMPSON-1 (NCT05286255)
- Testing
- Allogeneic Mesenchymal Stromal Cells
- Where
- United States
- Sponsor
- Medical University of South Carolina
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