Clinical trials: Covid-19 Patients
COVID-19
Efficacy of Breathox Device Inhalation Therapy in the Treatment of Acute Symptoms Associated With COVID-19 and in the Prevention of the Use of Health Resources
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), the new coronavirus, causes a disease called COVID-19 that can trigger aggressive inflammatory responses.
- Trial name
- BREATH (NCT05196581)
- Testing
- Dispersible NaCl powder 10 sessions, Dispersible NaCl powder 5 sessions
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Suzana Erico Tanni Minamoto
COVID-19
Relation Between COVID-19 Pts and Hyponatremia in Adreno Ortical Insufficient Patients.
Hyponatremia in COVID-19 patients with adrenal insufficiency
- Trial name
- NCT05408481
- Testing
- Serum cortisol level
- Volunteers
- 50 people
- Sponsor
- Assiut University
Covid19
Is Bio-adrenomedullin (Bio-ADM) a Prognostic Factor in Patients With COVID-19 Treated in the ICU?
This is prospective, observational study using point of care test to determine bio-ADM whole blood concentrations and its predictive value in patients with COVID-19 treated in the ICU.
- Trial name
- NCT04813939
- Testing
- IB10 sphingotest® bio-ADM® apparatus (Sphingotec GmbH, Hennigsdorf, Germany)
- Where
- Poland
- Volunteers
- 32 people
- Sponsor
- Medical University of Warsaw
Lung Cancer, Covid19
Anti-SARS-COV2 Vaccination Study in Lung Cancer Patients
Observational and multicenter retrospective study of data collection in hospital centers throughout the Spanish geography. This study aims to be nationwide in order to study general common variables of the patients, as well as…
- Trial name
- VAC-CaP (NCT05009030)
- Testing
- COVID-19 vaccine
- Where
- 51 sites in Spain
- Volunteers
- 794 people
- Sponsor
- Fundación GECP
Cancer, Immune Checkpoint Inhibitors
COVICI-SURV: COVID-19 Vaccination Around ICI Start and Survival
COVICI-SURV is a nationwide, retrospective observational cohort study using the French national health data system (SNDS) to evaluate whether COVID-19 vaccination, particularly mRNA vaccination, received within 100 days before or…
- Conditions
- Cancer, Immune Checkpoint Inhibitors, COVID-19 Vaccination, Survival
- Trial name
- COVICI-SURV (NCT07729241)
- Where
- France
- Volunteers
- 95,015 people
- Sponsor
- Groupe Hospitalier Pitie-Salpetriere
COVID-19
Phase IIa Randomized Placebo Controlled Clinical Study of Codivir in Hospitalized Patients with Moderate COVID-19
This is a double-blind, multicentre, multinational study to evaluate the safety and collect preliminary efficacy data of Codivir drug product in 130 hospitalized adults with moderate COVID-19 symptoms.
- Trial name
- NCT05218356
- Testing
- Covidir injections, Quantitative PCR SARS-CoV-2, IgM and IgG dosage
- Where
- 5 sites in Brazil
- Volunteers
- 130 people
- Sponsor
- Code Pharma
COVID-19, Emergency Surgery
Treatment and Outcomes in Patients With COVID-19 and Competing Acute Surgical Diseases in Moscow
The COVID-19 pandemic has posed a significant challenge to surgical practice. This study aims to investigate the structure of hospitalizations, treatment outcomes, and surgical tactics in patients with COVID-19 and competing…
- Conditions
- COVID-19, Emergency Surgery, Abdominal Surgery, Real-World Data
- Trial name
- SurgCOVID-Mos (NCT07719166)
- Testing
- Surgical and Interventional Management of Acute Surgical Conditions
- Where
- Russia
- Volunteers
- 58,000 people
- Sponsor
- Pirogov Russian National Research Medical University
Coronavirus, Pneumonia
Closed-Loop Oxygen to Verify That Healthcare Workers Interventions Decrease During SARS-CoV-2 Pneumonia (COVID-19)
There is a high risk of transmission of COVID-19 to healthcare workers. In a recent cohort, 29% of the patients hospitalized were healthcare workers.
- Conditions
- Coronavirus, Pneumonia, Oxygen Toxicity
- Trial name
- NCT04320056
- Testing
- Standard administration of oxygen flow, Automated oxygen administration - FreeO2
- Where
- Canada
- Volunteers
- 216 people
- Sponsor
- Laval University
Covid-19, Hypoxia
Hydrocortisone for COVID-19 and Severe Hypoxia
We aim to assess the benefits and harms of low-dose hydrocortisone in patients with COVID-19 and severe hypoxia.
- Trial name
- COVID STEROID (NCT04348305)
- Testing
- Hydrocortisone, Sodium Chloride 9mg/mL
- Where
- 14 sites in Denmark
- Volunteers
- 30 people
- Sponsor
- Scandinavian Critical Care Trials Group
Olfactory and Taste Dysfunction in SARS-CoV2 Infection
EFFECT OF COVID-19 DISEASE IN SMELL AND TASTE OF PATIENTS WITH MILD, MODERATE OR SEVERE SYMPTOMATOLOGY
This is an observational data and recording study. The aim of our study is to investigate the effect of SARS-COV2 infection on patients' sense of smell and taste, through quality control measurements using optic analogue scale…
- Trial name
- NCT04657445
- Testing
- visual analogue scale
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ioannina
COVID-19, SARS-CoV 2
Efficacy and Safety Evaluation of Mesenchymal Stem Cells for the Treatment of Patients With Respiratory Distress Due to COVID-19
Randomized, double-blind, parallel, two-arms clinical trial to assess the efficacy and safety of 2 infusions of Wharton-Jelly mesenchymal stromal cells (day 1 and day 3, endovenously at 1E6cells/Kg per dose) in patients with…
- Conditions
- COVID-19, SARS-CoV 2, Adult Respiratory Distress Syndrome
- Trial name
- COVIDMES (NCT04390139)
- Testing
- XCEL-UMC-BETA
- Where
- 5 sites in Spain
- Volunteers
- 26 people
- Sponsor
- Banc de Sang i Teixits
COVID-19
Clinical Study for the Efficacy and Safety of Ropeginterferon Alfa-2b in Adult COVID-19 Patients With Comorbidities
To evaluate the efficacy of subcutaneous ropeginterferon alfa 2b ( P1101 combined with standard of care (SOC) compared with standard care alone in adult COVID-19 patients with comorbidities.
- Trial name
- NCT05808322
- Testing
- Ropeginterferon alfa-2b, SOC
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Anxiety
Intensive Care Anxiety in SARS-CoV-2 Patients
It should be known by the clinician that COVID-19 patients are prone to anxiety, and these disorders need to be properly diagnosed and addressed to improve prognosis, shorten hospital stay and avoid long-term mental health…
- Trial name
- NCT04715477
- Testing
- Hospital Anxiety Depression Measure
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Derince Training and Research Hospital
Cardiovascular Diseases, Cardiovascular Risk Factor
Characterization of Cardiovascular Diseases and Risk Factors in Patients With Suspected SARS-CoV2/Covid-19 Infection
The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infects host-cells via ACE2-receptors, which leads to pneumonia (COVID-19) but also can lead to myocarditis (acute myocardial injury) and chronic damage to the…
- Conditions
- Cardiovascular Diseases, Cardiovascular Risk Factor, SARS
- Trial name
- NCT04327479
- Testing
- Assessment of cardiovascular diseases and cardiovascular risk factors
- Where
- Germany
- Volunteers
- 728 people
- Sponsor
- University Hospital, Essen
COVID-19
Effect of Virtual Reality in Patients With Long Covid-19
SARS-CoV-2 was first detected in Wuhan, Hubei Province, China, in late 2019. It is a highly contagious virus that has been reported to occur in humans and is said to cause pneumonia.
- Trial name
- NCT06374446
- Testing
- Classical Treatment, Virtual Reality Combined with Classical Treatment, Virtual Reality
- Volunteers
- 56 people
- Sponsor
- Istinye University
COVID-19 Patients
Hydroxychloroquine in Combination With Sirolimus and Dexamethasone for Treating COVID-19 Patients
COVID-19 caused an unprecedented international crisis. There is an urgent need for an effective regimen to cure this illness. Anecdotal data and some prospective results suggested a role of antimalarial drugs (chloroquine and…
- Trial name
- COVID19-HOPE (NCT04374903)
- Testing
- HCQ & AZ vs HCQ+SIR
- Where
- Jordan
- Sponsor
- King Hussein Cancer Center
Covid19, AKI
Global Assessment of Acute and Chronic Kidney Disease Incidence and Outcomes in Patients With COVID-19 Infection
The coronavirus (COVID-19) pandemic has created a significant strain on health care resources across the world for managing critically ill patients.
- Conditions
- Covid19, AKI, CKD, ESRD
- Trial name
- NCT04491227
- Where
- 12 sites in United States, Bolivia and 4 more
- Volunteers
- 2,000 people
- Sponsor
- University of California, San Diego
Corona Virus Infection, SARS-CoV 2
Registry for Clinical Presentation and Management of Patients With COVID-19 in the Emergency Room
Patients with COVID-19 usually present in the ED and receive their initial medical check-up here. We will try to gather information of comorbidities and other conditions at the time of presentation of COVID-19 patients to the ED.
- Trial name
- ReCovER (NCT04351854)
- Testing
- Retrospective data collection
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- University of Cologne
Multiple Sclerosis, Healthy
COVID-19 Vaccine Response in Treated MS Patients
The primary goal of this study is to assess the impact of the two major disease modifying therapy (DMT) classes (B cell therapies and S1P modulators) on humoral and cell-mediated immunity to SARS- CoV-2 vaccination compared to…
- Trial name
- NCT05060354
- Testing
- Blood draw
- Where
- United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Thalassemia Major, Covid19
Frequency of COVID-19 Antibodies in Patients With Hereditary Hematological Diseases
In Italy there are about 5000 patients with dependent transfusion thalassemia (source Italian Thalassemia and Hemoglobinopathies - SITE) and a smaller number, currently not definable, of patients with sickle cell anemia in…
- Trial name
- ThalaCoV (NCT04526405)
- Testing
- SARS-CoV-2 S1/S2 IgG
- Where
- Italy
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Milano Bicocca
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