Clinical trials: Covid-19 Patients
COVID-19
Proof of Concept Study to Evaluate the Safety Profile of Plitidepsin in Patients With COVID-19
In December 2019, Wuhan, in Hubei province, China, became the center of an outbreak of pneumonia of unknown cause. In a short time, Chinese scientists had shared the genome information of a novel coronavirus (SARS-CoV-2) from…
- Trial name
- APLICOV-PC (NCT04382066)
- Testing
- Plitidepsin 1.5 mg/day, Plitidepsin 2.0 mg/day, Plitidepsin 2.5 mg/day
- Where
- 13 sites in Spain
- Volunteers
- 46 people
- Sponsor
- PharmaMar
Cancer, COVID
The GCO-002 CACOVID-19 Cohort: a French Nationwide Multicenter Study of COVID-19 Infected Cancer Patients
Since December 2019, China and then the rest of the world have been affected by the rapid development of a new coronavirus, SARS-CoV-2 (severe acute respiratory syndrome corona virus 2).
- Conditions
- Cancer, COVID, Solid Tumor, Social Inequality
- Trial name
- CACOVID-19 (NCT04397575)
- Where
- 148 sites in France
- Volunteers
- 1,523 people
- Sponsor
- Federation Francophone de Cancerologie Digestive
COVID-19
Study on the Recovery of Pulmonary Function, Chest CT, Airway Microbiota, Hematologic, and Immune & Inflammatory Conditions in COVID-19 Rehabilitation Patients
The intent of this study was to examine the health status of individuals who had been confirmed with COVID-19 in the year after their recovery.
- Trial name
- NCT04456101
- Where
- China
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
COVID-19
Intranasal Lavage With Hypochlorous Acid Safely Reduces the Symptoms in the Ambulatory Patient With COVID-19.
The goal of this observational study is to determine if intranasal lavage reduces symptoms in adults with COVID-19. The main question is can a hypochlorous acid solution reduce the symptoms of COVID-19.
- Trial name
- NCT05950295
- Testing
- Intranasal lavage with hypochlorous acid solution
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Monique Lisa Abner
COVID-19
Long-term Outcomes in Patients With COVID-19
Long-term outcomes from coronavirus disease 2019 (COVID-19) are currently unknown. This study will collect daily living status of survivors of COVID-19.
- Trial name
- NCT04508712
- Where
- China
- Volunteers
- 900 people
- Sponsor
- RenJi Hospital
Cardiovascular Diseases, Cardiovascular Risk Factor
Digital Cardiac Counseling Trial: DCC Trial
Most patients undergoing a cardiovascular procedure need an ICU-bed during the hospitalization and therefore it is possible that for the unforeseen future, because of the Covid-19 crisis, many patients will stay on the waiting…
- Trial name
- DCC (NCT04393636)
- Testing
- Digital cardiac Counseling
- Where
- Netherlands
- Volunteers
- 394 people
- Sponsor
- Academisch Ziekenhuis Maastricht
Patient Admitted to Intensive Care Unit for COVID-19
FOLLOW-UP OF PATIENTS WITH COVID-19.
Some patients admitted to intensive care for a severe form of COVID-19 could have respiratory, cardiac, renal and neurological sequelae in the medium or long term.
- Trial name
- TeleRea'nCo (NCT04609839)
- Testing
- Follow-up of patients with COVID-19
- Where
- France
- Sponsor
- University Hospital, Strasbourg, France
Prone Position, Severe Acute Respiratory Syndrome Coronavirus 2
Evaluation of Sedation in COVID-19 ARDS
This study focuses on the evaluation of various factors repeatedly discussed in relation to the impaired sedation of intubated ventilated COVID-19 patients.
- Conditions
- Prone Position, Severe Acute Respiratory Syndrome Coronavirus 2, Hypnotics and Sedatives, Pulmonary Ventilation
- Trial name
- NCT04667936
- Testing
- Treatment group
- Where
- Germany
- Volunteers
- 114 people
- Sponsor
- Goethe University
COVID-19
Investigation of the Muscle Oxygenation in Patients With Post COVID-19 Syndrome
More than 60% of patients infected with COVID-19 have long-term symptoms. These symptoms are associated with common ground-glass opacities on computed tomography scans and chest radiographs.
- Trial name
- NCT05957575
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Gazi University
Cardiac Surgery, COVID
Patient Recovery From Heart Surgery During the Covid-19 Pandemic
This study will describe and explore the recovery process of patients undergoing cardiac surgery during the covid-19 pandemic. This will include mortality, morbidity, health-related quality of life, event-specific distress and…
- Trial name
- CardiacCovid (NCT04366167)
- Testing
- Cardiac surgery
- Where
- United Kingdom
- Volunteers
- 253 people
- Sponsor
- Barts & The London NHS Trust
Covid19, Respiratory Function Loss
Effect of Respiratory Exerciser on Pulmonary Functions of COVID-19 Patients
COVID-19 infection is the cause of the current pandemic, responsible for loss of life and disability at a rate unseen before. Among survivors, the infection may cause lasting damage, such as permanent loss of lung function.
- Conditions
- Covid19, Respiratory Function Loss, Coronavirus Infection, Pneumonia, Viral
- Trial name
- NCT04826731
- Testing
- Incentive Spirometer/Respiratory Exerciser
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Type 1 Diabetes
COVID-19 Pandemic Lockdown Effect in Adolescents and Young Adults With Type 1 Diabetes: Positive Results of an Unpreceded Challenge for Telemedicine and Patient Self-management
Lockdown resulting from the COVID-19 pandemic was an unpreceded model of the impact of lifestyle on chronic diseases, especially for adolescents and young adults with type 1 diabetes (T1D) whose lifestyle is known to strongly…
- Trial name
- COVIDIABADO (NCT04669912)
- Testing
- glucose control and sensor usage
- Where
- France
- Volunteers
- 77 people
- Sponsor
- Centre Hospitalier Sud Francilien
Corona Virus Infection
Glucocorticoid Therapy in Coronavirus Disease COVID-19 Patients
Treatment with glucocorticoids in COVID patients. Low-intervention, phase IV, open-label, randomised, low-intervention clinical trial comparing 2 active treatments.
- Trial name
- NCT04780581
- Testing
- Dexamethasone, Methylprednisolone
- Where
- 4 sites in Spain
- Volunteers
- 128 people
- Sponsor
- Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León
COVID-19
Efficacy and Safety of Hydroxychloroquine and Azithromycin for Patients With Moderate to Severe COVID-19
This is an exploratory study to evaluate the efficacy of hydroxychloroquine (400 mg BID on D1 and 400 mg/day on D2 to D5) and azithromycin (500 mg/ 5 days) to treat moderate to severe COVID-19 pneumonia.
- Trial name
- NCT04329572
- Testing
- Hydroxychloroquine Sulfate, Azithromycin Tablets
- Where
- Brazil
- Volunteers
- 400 people
- Sponsor
- Azidus Brasil
Covid-19, Pulmonary Embolism
Pulmonary Embolism and COVID-19
The charts of patients who developed pulmonary embolism in the course of COVID-19 will be evaluated, retrospectively. Clinical features and laboratory data will be analyzed.
- Trial name
- COVID-19-PE (NCT04590378)
- Testing
- intensive care unit admission ratio
- Where
- Turkey (Türkiye)
- Volunteers
- 600 people
- Sponsor
- Uşak University
COVID-19, ARDS
Losartan and Spironolactone Treatment for ICU Patients With COVID-19 Suffering From ARDS
Coronavirus disease (COVID-19) is a current pandemic infection caused by an RNA virus called Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2).
- Trial name
- COVIDANCE (NCT04643691)
- Testing
- Losartan 50 mg and Spironolactone 25 mg pillules oral use
- Where
- France
- Volunteers
- 78 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
COVID-19, Surgery
The Effect of COVID-19 Infection on Post-operative Complications
We did an multi-centre, observational cohort study in patients who had surgery in 2023. We included participants who underwent surgery after the COVID-19 to lift the lockdown in China.
- Conditions
- COVID-19, Surgery, Postoperative Complications
- Trial name
- NCT05677815
- Testing
- Underwent Surgery from 2019 to 2022
- Where
- China
- Volunteers
- 3,350 people
- Sponsor
- Xijing Hospital
Post-acute COVID-19 Syndrome
SENSING-AI Cohort for Long COVID Patients
The prospective study will focus on the collection of biometric and psychometric data from a limited population for 1 month with the aim of complementing the SENSING-AI retrospective cohort.
- Trial name
- SENSING-AI (NCT05204615)
- Testing
- Collection of clinical, psychometric and biometric data
- Where
- 2 sites in Spain
- Volunteers
- 10 people
- Sponsor
- Adhera Health, Inc.
COVID-19, Cytokine Storm
Intercellular Adhesion Molecule-1 and TNF-α in Patients With COVID-19
This study aimed to assess the cytokine profile in COVID 19 patients and its relation with disease progression \& severity using COVID reporting and data system (CORADS) score.
- Trial name
- NCT05408325
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Benha University
Hyponatremia, Covid19
HYPONATREMIA IN COVID-19 PATIENTS
SYSTEMIC INFLAMMATION HAS BEEN ASSOCIATED WITH SEVERE COVID-19. HYPONATREMIA CAN RESULT FROM INFLAMMATION DUE TO NON-OSMOTIC STIMULI FOR VASOPRESSIN PRODUCTION.
- Conditions
- Hyponatremia, Covid19, Corona Virus Infection
- Trial name
- NCT04493268
- Where
- Argentina
- Volunteers
- 250 people
- Sponsor
- Hospital Nacional Profesor Alejandro Posadas
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