Clinical trials: Covid-19 Pneumonia
COVID-19, Hypertension
Hypertension in Patients Hospitalized With COVID-19
Some studies have shown that the main pathogenesis of patients with covid19 is related to ACE2 receptor. Lung is one of the main organs, and there are many ACE2 receptors in cardiovascular system.
- Trial name
- HT-COVID19 (NCT04318301)
- Where
- China
- Volunteers
- 275 people
- Sponsor
- Zhenhua Zen
Covid19, Vertical Transmission of Infectious Disease
Clinical Outcomes of Newborns Born to Pregnant Women With and Without COVID-19
A case-control trial was conducted to test the early postpartum period clinical outcomes of newborns born to pregnant women with and without COVID-19.
- Conditions
- Covid19, Vertical Transmission of Infectious Disease, Neonatal Infection, Pregnancy Related
- Trial name
- NCT04883801
- Testing
- Reviewed clinical records and laboratory results
- Where
- Turkey (Türkiye)
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
COVID-19
Critically Ill Patients With COVID-19 in Hong Kong: a Multicentre Observational Cohort Study
The purpose of this case series is to describe the characteristics, organ dysfunction and support and 2 week outcomes of critically ill patients with nCov infection.
- Trial name
- NCT04285801
- Where
- 3 sites in Hong Kong
- Volunteers
- 8 people
- Sponsor
- Chinese University of Hong Kong
Covid19, COVID19 Infection
State of Oxygen Metabolism, Cardiovascular and Respiratory System Reserve Capacity in Patients Who Underwent COVID-19
This clinical study will create an evidence base for rehabilitation approach, which will be used for restoration of pulmonary ventilation and gas exchange, increase of tolerance to physical load reduced in patients who underwent…
- Trial name
- NCT05911100
- Testing
- Spirography and assessment of pulmonary diffusion capacity, Cardiopulmonary stress test, Computed tomography of the chest organs
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
COVID-19
Ivermectin for Severe COVID-19 Management
In this multicenter study; it was aimed to investigate the effectiveness and safety of ivermectin use in the treatment of patients with severe COVID-19 pneumonia that have no mutations which alter ivermectin metabolism and cause…
- Trial name
- NCT04646109
- Testing
- Ivermectin
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
COVID-19
COVID-19 Self-testing IMPROVE
The study aims to engage community partners to implement IMPROVE intervention and promote (COVID-19) rapid testing among vulnerable Asian Americans in the Greater Philadelphia Area and New York City
- Trial name
- NCT06576167
- Testing
- IMPROVE
- Where
- United States
- Volunteers
- 1,277 people, healthy volunteers welcome
- Sponsor
- Temple University
SARS-CoV-2 Infection (Asymptomatic), SARS-CoV-2 Infection (Symptomatic)
COVID-19 Progression in End-Stage Kidney Disease
The purpose of this study is to collect genomic and clinical data among a cohort of hemodialysis patients and analyze the association between genetic markers and the development and severity of illness in response to SARS-CoV-2.
- Trial name
- COPE (NCT04495907)
- Where
- 11 sites in United States
- Volunteers
- 412 people
- Sponsor
- Davita Clinical Research
COVID-19
Mortality, Gravity Predictive Factors and Clinical Evolution of Older COVID-19 Patients in Short Geriatric Services.
Since the beginning of the year 2020, clinical characteristics of a new disease as the global COVID-19 epidemic has spread in France.
- Trial name
- GERICOVID (NCT05455892)
- Testing
- Clinical data collection during hospitalization in short geriatric units.
- Where
- 5 sites in France
- Volunteers
- 450 people
- Sponsor
- Hospices Civils de Lyon
Heart Failure, Covid19
Impact of COVID-19 on the Benefit of Cardiac Rehabilitation
The COVID-19 attack is polymorphic with otorhinolaryngological, pneumological, cardiac, digestive, neurological, muscular attacks with a higher mortality in subjects with comorbidity [> 70 years old, cardiovascular history in…
- Trial name
- REACARDIOCOVID (NCT04513964)
- Sponsor
- Fondation Hôpital Saint-Joseph
COVID-19
Study of Professional and Individual Factors of Covi-19 and Impact on Return to Work
Started on January 9, 2020 with the announcement of the discovery of a new SARS-CoV-2 coronavirus, the Covid-19 pandemic is responsible as of June 21, 2020 for 160,377 confirmed cases in France, 29,640 deaths and 9,823…
- Trial name
- FP-COVID-19 (NCT05616663)
- Where
- France
- Volunteers
- 639 people
- Sponsor
- University Hospital, Strasbourg, France
COVID-19
Phase III Double-blind, Placebo-controlled Study of AZD7442 for Pre-exposure Prophylaxis of COVID-19 in Adult.
This study will assess the safety and efficacy of a single dose of AZD7442(× 2 IM injections) compared to placebo for the prevention of COVID-19.
- Trial name
- PROVENT (NCT04625725)
- Testing
- AZD7442
- Where
- 89 sites in United States, Belgium and 3 more
- Volunteers
- 5,197 people
- Sponsor
- AstraZeneca
Mild Cognitive Impairment, Dementia
Cognitive Outcomes During COVID-19 confiNemeNt in Elderly and Their Caregivers Using Technologies for DEMentia
Coronavirus disease 2019 has forced worldwide the implementation of unprecedented restrictions to control its rapid spread and mitigate its impact.
- Trial name
- CONNECTDEM (NCT04385797)
- Testing
- Telephone interview
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Covid19, Cognitive Impairment
Assessment of Executive Functions After Covid-19
As it is evident that Covid-19 may have some impacts on cognition, the primary aim of this study is to investigate -if any- deficits of attention, working memory and executive functions after Covid-19.
- Trial name
- NCT04771624
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Acute Respiratory Infection
A Study of Acute Respiratory Infections in Global Outpatient Setting
The purpose of this study is to evaluate the positivity rate of respiratory syncytial virus (RSV), influenza virus and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in high-risk participants presenting with acute…
- Trial name
- ARGOS (NCT05148780)
- Testing
- Nasal Swab Sample
- Where
- 72 sites in United States, Canada and 8 more
- Volunteers
- 245 people
- Sponsor
- Janssen Research & Development, LLC
COVID-19
Booster Study of SpikoGen COVID-19 Vaccine
The purpose of the study is to assess the effectiveness of Spikogen vaccine when used as a 3rd or 4th dose booster in adults who have been previously vaccinated with any Covid-19 vaccine types, including mRNA vaccine, adenoviral…
- Trial name
- NCT05542862
- Testing
- SpikoGen vaccine
- Where
- Australia
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Vaxine Pty Ltd
Covid19
COVID-19 Citizen Science Expansion Project
COVID-19 Citizen Science (CCS), launched in March 2020, supports collaborative research on symptoms, risk factors, surveillance, biomarkers and testing for COVID-19 using the Eureka Research Platform.
- Trial name
- NCT05548803
- Where
- 9 sites in United States
- Volunteers
- 52,351 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
covid19
Evaluation of the Efficacy of Mouth Rinses With Commercial Mouthwashes to Decrease Viral Load in Saliva in COVID-19 Patients
As no curative treatment for SARS-CoV-2 is currently available, most public health measures to contain the pandemic are based on preventing the spread of the pathogen.
- Trial name
- NCT05543603
- Testing
- Lacer Clorhexidina Colutorio, Lacer Clorhexidine 0.20% Colutorio, Gingilacer Encías Delicadas Colutorio
- Where
- 4 sites in Spain
- Volunteers
- 48 people
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
COVID-19
Infliximab in the Treatment of Patients With Severe COVID-19 Disease
In this trial, patients that are severely affected by the disease COVID-19 will either receive infliximab, an anti-inflammatory drug, or standard therapy.
- Trial name
- INFLIXCOVID (NCT04922827)
- Testing
- Infliximab, Standard of Care
- Where
- 4 sites in Germany
- Volunteers
- 9 people
- Sponsor
- Jena University Hospital
SARS-CoV-2
A Study to Evaluate the Immunogenicity and Safety of Omicron Variant Vaccines in Comparison With mRNA-1273 Booster Vaccine for COVID-19
This is a 2-part study to evaluate the immunogenicity, safety, and reactogenicity of mRNA-1273.529 and mRNA-1273.214 administered as a booster dose.
- Trial name
- NCT05249829
- Testing
- mRNA-1273.529, mRNA-1273, mRNA-1273.214
- Where
- 29 sites in United Kingdom
- Volunteers
- 3,548 people, healthy volunteers welcome
- Sponsor
- ModernaTX, Inc.
Covid19
Cardiac Assessment After Covid-19 Disease in Elite Altheltic Population
COVID-19 infection coud induce cardiac injuries. Before returning to sport, cardiac evaluation is recommended by sports federations, based on the precautionary principle and the opinion of expert consensus.
- Trial name
- CADE (NCT04653857)
- Where
- France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Montpellier
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