Clinical trials: Covid-19 Pneumonia
Covid19
Study to Reinforce Immunity (STRI) Phase 2 Clinical Trial
Protocol STRI12 - Study to Reinforce Immunity (STRI) - A Phase 2 Double-Blind, Randomized, Placebo-Controlled Study to Investigate the Safety and Efficacy of STRI Formula in Non-Hospitalized Participants with COVID-19 (the Study)
- Trial name
- NCT05046561
- Testing
- STRI Formula
- Where
- 13 sites in United States
- Volunteers
- 598 people
- Sponsor
- Eyecheck, Inc.
Covid19
A Trial Using ANAKINRA, TOCILIZUMAB Alone or in Association With RUXOLITINIB in Severe Stage 2b and 3 of COVID19-associated Disease
COVID19-associated disease may have different clinical aspects classified in 3 stages. Some patients initially presenting with a non-hypoxemic viral pneumonia (stage 2a) may evolve toward a more severe stage 2b or 3 (acute…
- Trial name
- INFLAMMACOV (NCT04424056)
- Testing
- Anakinra +/- Ruxolitinib (stages 2b/3), Anakinra and Ruxolitinib (Advanced stage 3), Tocilizumab +/- ruxolitinib (stages 2b/3)
- Where
- France
- Volunteers
- 216 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
COVID-19 Pneumonia, Coronavirus Infections
Clinical Trial on Sequential Immunization of Recombinant COVID-19 Vaccine (CHO Cells,NVSI-06-08) and Inactivated COVID-19 Vaccine (Vero Cells) in Population Aged 18 Years and Above
This is randomized, blinded and controlled design. Among the randomly selected subjects who have been vaccinated with two doses of Inactivated COVID-19 vaccine (Vero cell), based on a step-wise approach, the subjects will receive…
- Trial name
- NCT05069129
- Testing
- Recombinant COVID-19 Vaccine (CHO cell,NVSI-06-08), Inactivated COVID-19 vaccine (Vero cells), 3 doses Recombinant COVID-19 Vaccine (CHO cell,NVSI-06-08)
- Where
- United Arab Emirates
- Volunteers
- 1,848 people, healthy volunteers welcome
- Sponsor
- National Vaccine and Serum Institute, China
Covid-19, Cognitive Impairment
Improving Thinking in Everyday Life After Covid-19
The purpose of this initial study is to evaluate a new form of cognitive rehabilitation therapy for improving your ability to think, particularly how rapidly you process information that you receive from your senses, e.g., sight…
- Trial name
- NCT04644172
- Testing
- Speed of Processing Training, Instrumental Activities of Daily Living Shaping, Transfer Package from CI Therapy
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Alabama at Birmingham
COVID-19, Coronavirus Infections
Safety, Tolerability, and Immunogenicity of Trivalent Coronavirus Vaccine Candidate VBI-2901a
VBI-2901a is an investigational vaccine candidate that uses enveloped virus-like particles (eVLPs) to express the spike proteins of three coronaviruses: SARS-CoV-2 (the virus that causes COVID-19 disease), SARS-CoV-1 and…
- Trial name
- NCT05548439
- Testing
- VBI-2901a
- Where
- 7 sites in Canada
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- VBI Vaccines Inc.
SARS-CoV 2, Traumatic Stress Disorder
Consequences of the QUARANTINE Relating to the COvid-19 Epidemic on the Mental Health of the Patients Followed in PSYchiatry
Quarantine related to the Covid-19 pandemic has begun on the 03/17/2020 in France. Quarantine has already be linked to pejorative effects on mental health.
- Trial name
- QUARCOPSY (NCT04405362)
- Sponsor
- University Hospital, Lille
Coronavirus Infection
Gerontological Telemonitoring of Older Adults Living in Nursing Homes With COVID-19 Disease
Since the last 3 months the world copes with the novel coronavirus disease : Covid-19 emerged in China in the end of 2019. WHO declared the pandemic situation as a Public Health Emergency around the world on January 2020.
- Trial name
- COVIDeHPAD (NCT04337788)
- Testing
- telehealth applications
- Where
- France
- Sponsor
- University Hospital, Limoges
COVID-19 Pulmonary Complications, COVID-19
Covid-19 Infection and Pulmonary Distress Treatment With Zanubrutinib in Hospitalized Participants
The primary objective of this study was to evaluate if the addition of zanubrutinib to supportive care increases the respiratory failure-free survival rate at Day 28 in participants hospitalized for Corona Virus Disease 2019…
- Trial name
- NCT04382586
- Testing
- Zanubrutinib, Supportive Care
- Where
- 10 sites in United States
- Volunteers
- 63 people
- Sponsor
- BeiGene
SARS-CoV-2 Infection, Influenza A
Usability and Clinical Validation of the Flu A/B/COVID-19 + RSV Multiplex Rapid Test
This will be a prospective study for the clinical validation of the CorDx Tyfast Flu A/B/COVID-19 + RSV Multiplex Rapid Test for the qualitative detection and differentiation of SARS-CoV-2, Influenza A, Influenza B and RSV in AN…
- Conditions
- SARS-CoV-2 Infection, Influenza A, Influenza B, RSV
- Trial name
- CorDx 4in1 (NCT07875270)
- Testing
- Flu A/B/COVID-19 + RSV Multiplex Rapid Test
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- CorDx, Inc.
Long Covid19, Autonomic Dysfunction
Autonomic Nervous System Affection Due to Post Covid Syndrome
Post-Covid syndrome is defined as symptoms that develop in addition to respiratory symptoms in individuals who have had Covid-19 infection for more than 12 weeks.
- Trial name
- NCT05502094
- Testing
- Heart Rate Variability Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Long COVID, Post COVID-19 Condition
Taurine Supplementation in Adolescents With Post-COVID Condition
The COVID-19 pandemic has swept across the globe, affecting millions of individuals with varying degrees of severity. While many individuals recover from the acute phase of the infection, a significant proportion continue to…
- Conditions
- Long COVID, Post COVID-19 Condition, PASC Post Acute Sequelae of COVID 19
- Trial name
- TaurineLCPeds (NCT07682402)
- Testing
- Taurine
- Volunteers
- 30 people
- Sponsor
- University of Alberta
COVID-19
Study of Remdesivir in Participants Below 18 Years Old With COVID-19
The goals of this clinical study are to learn more about the study drug, remdesivir, and how safe it is in participants less than 18 years old with coronavirus disease 2019 (COVID-19).
- Trial name
- CARAVAN (NCT04431453)
- Testing
- Remdesivir
- Where
- 32 sites in United States, Italy and 2 more
- Volunteers
- 59 people
- Sponsor
- Gilead Sciences
Covid19, Patient Reported Outcome Measures, Quality of Life
Development of an International COVID-19 Specific Quality of Life Questionnaire, Phase III. The OSLO COVID-19 QLQ
Purpose: to develop an international validated patient-reported outcome measure for COVID-19 patients according to international guidelines.
- Trial name
- NCT04740372
- Testing
- No intervention. Method study. Psychometric testing
- Where
- Norway
- Volunteers
- 371 people
- Sponsor
- Oslo University Hospital
Covid19
Short Term Low Dose Corticosteroids for Management of Post covid19 Pulmonary Fibrosis
A randomized controlled trial to study the efficacy of low dose steroid for 14 days in the treatment of post-covid-19 lung infiltrates
- Trial name
- NCT04551781
- Testing
- 20 Mg Prednisone for 14 days, control
- Where
- Egypt
- Volunteers
- 450 people
- Sponsor
- South Valley University
Loneliness
Preliminary Efficacy of a One-Session Mindfulness Telehealth Intervention for Loneliness
The primary aim of this study is to examine the efficacy of a one-session, hour-long HIPAA-compliant video platform-based mindfulness + compassion telehealth intervention on reducing feelings of loneliness during COVID-19…
- Trial name
- NCT04414826
- Testing
- Mindfulness Alone (MO) Intervention, Mindfulness + Compassion Intervention (MC)
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
COVID-19
Evaluating the Safety and Efficacy of AD17002 Intranasal Spray in Treating Participants With Mild to Moderate COVID-19
AD17002 enhances nasal mucosal innate immunity and has met safety and efficacy endpoints in studies of nasal adjuvants or intranasal immunomodulators.
- Trial name
- NCT05541510
- Testing
- AD17002 + Formulation buffer
- Where
- 3 sites in Indonesia
- Volunteers
- 180 people
- Sponsor
- Advagene Biopharma Co. Ltd.
Covid19, ARDS
Noninvasive Ventilation in Moderate-to-severe COVID-19-associated Acute Respiratory Distress-syndrome
Non-invasive ventilation can allow to avoid intubation and improve outcomes in moderate-to-severe COVID-19-associated acute respiratory distress-syndrome (ARDS).
- Trial name
- COVID-NIV (NCT04667923)
- Testing
- Respiratory monitoring, Respiratory muscles ultrasound, Electro impedance tomography
- Where
- Russia
- Volunteers
- 80 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
COVID-19 Pneumonia, COVID-19 Respiratory Infection
Safety and Effectiveness of an Immunobiological Drug in CoViD-19
The aims of this study is to analyze the efficacy and safety of a passive immunotherapy strategy using hyperimmune equine serum known as Anti-SARS-CoV-2 elaborated by the National Institute for the Production of Biologicals…
- Conditions
- COVID-19 Pneumonia, COVID-19 Respiratory Infection, Covid19
- Trial name
- INPB001 (NCT04913779)
- Testing
- Anti-SARS-CoV-2
- Where
- Argentina
- Volunteers
- 200 people
- Sponsor
- Administracion Nacional de Laboratorios e Institutos de Salud Dr. Carlos G. Malbran
Covid19
Evaluation of the Efficacy of High Doses of Methylprednisolone in SARS-CoV2 ( COVID-19) Pneumonia Patients
This double blind, randomized study is aiming to evaluate the efficacy of three doses (1gr/day) of methylpredisolone added to standard therapy in patients, with documented COVID-19 pneumonia, requiring hospitalization but not…
- Trial name
- NCT04673162
- Where
- 20 sites in Italy
- Volunteers
- 260 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Covid19, Corona Virus Infection
SPI-1005 Treatment in Moderate COVID-19 Patients
The study is a randomized, double-blind, placebo-controlled, dose escalation, multi-center clinical trial (RCT) of SPI-1005 in adult subjects with positive PCR test for novel SARS-CoV-2 (nCoV2) and moderate symptoms of COVID-19…
- Conditions
- Covid19, Corona Virus Infection, Coronavirus, Coronavirus Infection
- Trial name
- NCT04484025
- Testing
- Ebselen
- Where
- 7 sites in United States
- Volunteers
- 60 people
- Sponsor
- Sound Pharmaceuticals, Incorporated
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