Clinical trials: Covid-19 Pneumonia
COVID-19, Coronavirus Infections
Audio Data Collection for Identification and Classification of Coughing
An open access study that will define and collect digital measures of coughing in multiple populations and public spaces using various means of audio data collection.
- Conditions
- COVID-19, Coronavirus Infections, Hay Fever, Asthma
- Trial name
- NCT04326309
- Where
- United States
- Volunteers
- 336 people, healthy volunteers welcome
- Sponsor
- HealthMode Inc.
COVID-19
Detection of Anti-COVID-19 Antibody Levels in an Hospital Population
COVID-19 (SARS-CoV-2) infection in health professionals represent a significant criticality both for the risk of spreading the disease and for the organizational aspects that follow.
- Trial name
- NCT04387929
- Testing
- Detection of anti-COVID-19 antibody level
- Where
- Italy
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
COVID-19
Influence of Nutritional Indices on the Prognosis of Patients With SARS-CoV-2 Infection
With the decline of virulence after the mutation of the SARS-CoV-2 , based on the national life and health and national development needs, the domestic SARS-CoV-2 infection epidemic prevention policy has changed, and the number…
- Trial name
- NCT05835102
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Juan Kang
COVID-19, Coronavirus Infections
Safety, Tolerability, and Immunogenicity of Trivalent Coronavirus Vaccine Candidate VBI-2901e With E6020 Adjuvant
VBI-2901e is an investigational vaccine candidate that uses enveloped virus-like particles (eVLPs) to express the spike proteins of three coronaviruses: SARS-CoV-2 (the virus that causes COVID-19 disease), SARS-CoV-1 and…
- Trial name
- NCT05614245
- Testing
- VBI-2901e
- Where
- 4 sites in Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- VBI Vaccines Inc.
SARS-CoV-2 Infection
Nitric Oxide Nasal Spray (NONS) as Prevention for Treatment of Individuals at Risk of Exposure to COVID-19 Infection
A multicenter, randomized, double-blinded, placebo-controlled, phase 3 clinical efficacy study evaluating nitric oxide nasal spray (NONS) as prevention for treatment of individuals at risk of exposure to COVID-19 infection.
- Trial name
- NCT05109611
- Testing
- Nitric Oxide, Nasal spray with isotonic saline
- Where
- 6 sites in Canada, Sri Lanka
- Volunteers
- 1,389 people, healthy volunteers welcome
- Sponsor
- Sanotize Research and Development corp.
Coronavirus Disease 2019 (COVID-19)
Pharmacokinetics, Safety, and Tolerability of CSL760, an Intravenous Anti-SARS-CoV-2 Hyperimmune Globulin, in Healthy Adult Subjects
CSL760 is a human hyperimmune product of the purified gamma immunoglobulin (IgG) fraction of human plasma containing polyvalent neutralizing antibodies to SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2).
- Trial name
- NCT04638634
- Testing
- CSL760
- Where
- Australia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- CSL Behring
COVID-19 Pandemic, Stressor, Psychological
Stress and Coping, Resilience, and Compassion Fatigue of Front-line Nurses During COVID-19 Pandemic
This is a cross-sectional research. The investigators plan to recruit about 250 front-line nurses who provided direct care to COVID-19 confirmed cases in a medical center in Taiwan.
- Conditions
- COVID-19 Pandemic, Stressor, Psychological, Mental Health Issue
- Trial name
- NCT05205564
- Testing
- This is a cross-sectional research design.
- Where
- 3 sites in Taiwan
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- National Taiwan University
COVID-19
The Evaluation of Nitric Oxide Generating Lozenges on Outcome in Newly Diagnosed COVID-19 Patient of African American and Hispanic Origin
This study is a multi-center, randomized, double blinded, prospective, placebo controlled study. Patients upon diagnosis of COVID-19 (Corona Virus Disease-19) will be eligible to participate in the study.
- Trial name
- NCT04601077
- Testing
- Nitric Oxide lozenges, 30 mg
- Where
- United States
- Volunteers
- 524 people
- Sponsor
- Nitric Oxide Innovations LLC
Cardiovascular Diseases
Effects of COVID-19 Pandemic on a Health Care System: Case Study of the CirculatORy System in LiThuania
Coronavirus disease of 2019 (COVID-19) affected the health care systems all around the world. The collateral damage of the pandemic on the cardiovascular (CV) care and CV mortality has been noticed and reported early.
- Trial name
- COVID-COR-LT (NCT05021575)
- Testing
- Data collection on outpatient care, Data collection on hospitalisation, Data collection on cardiovascular mortality
- Where
- 3 sites in Lithuania
- Volunteers
- 839,678 people
- Sponsor
- Vilnius University
SARS-CoV Infection, Covid19
COVID-19: SARS-CoV-2 Detection in Saliva, Oropharyngeal and Nasopharyngeal Specimens
The aim of this study is to compare the SARS-CoV-2 detection rate using either a Saliva, oropharyngeal swabs or nasopharyngeal swab method for specimen collection.
- Conditions
- SARS-CoV Infection, Covid19, Coronavirus
- Trial name
- NCT04715607
- Testing
- Sequence of testing.
- Where
- Denmark
- Volunteers
- 27,947 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
COVID-19
Immunogenicity and Safety Study of the 3rd Booster Dose Using the High or Medium Dose of Inactivated Vaccine in Healthy Adults in in Hong Kong
This is a randomized, double-blinded, Phase IIb clinical trial of COVID-19 vaccine (CoronaVac®) manufactured by Sinovac Research \& Development Co., Ltd.The purpose of this study is to evaluate to evaluate the changes in…
- Trial name
- NCT05254236
- Testing
- COVID-19 Vaccine (Vero Cell), Inactivated (Medium-dose), COVID-19 Vaccine (Vero Cell), Inactivated (High-dose)
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sinovac Research and Development Co., Ltd.
SARS-CoV2 Infection
Use of Saliva for COVID-19 Diagnosis
Aim of the study is to evaluate the presence of SARS-CoV2 RNA in the saliva of patients with suspected or confirmed COVID-19 in order to validate the analysis of this type of sample for the diagnosis of SARS-CoV2 infections.
- Trial name
- SALIVA-01 (NCT04953039)
- Where
- Italy
- Volunteers
- 109 people
- Sponsor
- University of Milano Bicocca
COVID-19
Effect of Bronchipret on Antiviral Immune Response in Patients With Mild COVID-19
There is currently an urgent need for effective and safe treatments of Coronavirus Disease (COVID) - 19 and the cytokine storm that is responsible for the development of patient's Acute Respiratory Distress Syndrome (ARDS).
- Trial name
- BroVID (NCT05276375)
- Testing
- Bronchipret
- Where
- Germany
- Volunteers
- 21 people
- Sponsor
- Dr. Frank Behrens
COVID-19, Post COVID-19 Syndrome
Different Treatment Options Used for Post Covid-19 Syndrome
This study aimed to assess functioning during the recovery phase post-COVID-19 and to evaluate symptoms prolonging after COVID-19 infection and how to manage these symptoms.
- Conditions
- COVID-19, Post COVID-19 Syndrome, Ginkgo Biloba, Piracetam
- Trial name
- NCT07722000
- Testing
- Ginkgo biloba, Piracetam, Ginkgo biloba and Piracetam
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Beni-Suef University
COVID-19
SARS-CoV-2 Infection in COVID-19 Vaccinated Patients
Vaccination of the population is crucial in the fight against the COVID-19 pandemic. Although most available vaccines have an estimated efficacy against symptomatic infection of 65-95%, this can be significantly reduced if the…
- Trial name
- COVID-IVAC (NCT05060939)
- Testing
- COVID-19 vaccinated people
- Where
- France
- Volunteers
- 1,072 people
- Sponsor
- Hospices Civils de Lyon
COVID-19, Mental Health Disorder
COVID-19 and Mental Health
The overall objective of this study is to assess the enormity of mental health outcomes among healthcare providers (nurses and physicians) exposed to COVID-19 during the time of the pandemic in the United States, specifically…
- Trial name
- NCT04407195
- Testing
- Exposure to the SARS-CoV-2
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Northeastern University
Tracheal Intubation, Infection
Comparison of VieScope vs. Macintosh Laryngoscope for Intubation in Level Cpersonal Protective Equipment Conditions
The current COVID-19 pandemic, this is especially since the transmission of SARS-CoV-2 is thought to occur mainly through respiratory droplets generated by coughing and sneezing, by direct contact with contaminated surfaces and…
- Conditions
- Tracheal Intubation, Infection, Projection
- Trial name
- NCT04363775
- Testing
- The standard Macintosh laryngoscope, The Vie Scope laryngoscope
- Where
- Poland
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Lazarski University
SARS-CoV-2, Covid19
Pathological Findings of Fatal COVID-19
The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a new coronavirus discovered in December 2019 in Wuhan, China and currently responsible of a worldwide outbreak and the death of more than 55,000 patients in…
- Conditions
- SARS-CoV-2, Covid19, Pathology, Intensive Care Units
- Trial name
- HISTOCOVID (NCT04675281)
- Testing
- 2 post-mortem transcutaneous lung biopsies (1 anterior ; 1 posterior) using anatomical landmarks
- Where
- 44 sites in France
- Volunteers
- 170 people
- Sponsor
- Nantes University Hospital
SARS-CoV-2
Case Series Study to Detect SARS-CoV-2 in Semen of COVID-19 Patients
A descriptive, clinical series, single-centre, national, biomedical study to determine the presence of SARS-CoV-2 in sperm samples from positive PCR patients for COVID-19 and to evaluate the presence of the virus in the sperm…
- Trial name
- COVID-19CAST (NCT04717011)
- Testing
- PCR test
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Igenomix
COVID-19, Coronavirus
Outcomes of Surgery in COVID-19 Infection: International Cohort Study (CovidSurg)
CovidSurg will capture real-world international data, to determine 30-day mortality in patients with COVID-19 infection who undergo surgery.
- Conditions
- COVID-19, Coronavirus, Surgery
- Trial name
- CovidSurg (NCT04323644)
- Testing
- Surgery
- Where
- Spain
- Volunteers
- 1,000 people
- Sponsor
- University of Birmingham
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