Clinical trials: Covid-19 Pneumonia
SARS-CoV-2 Infection
Study of Specific Viral Immune Responses Induced by SARS-CoV-2 (COVID-19)
SARS-CoV-2, has caused an international outbreak of respiratory illness termed Covid-19. The investigators used peptides derived from SARS-CoV-2 virus, to study viral-specific immune responses.
- Trial name
- COV-CREM (NCT04365322)
- Testing
- Additional biological samples
- Where
- France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Covid19, Delirium
Neurotropism and Neuroinflammation in COVID-19 Patients With Delirium.
Emerging evidence indicates that SARS-CoV-2, the etiologic agent of COVID-19, can cause neurological, neuropsychological and psychiatric complications.
- Conditions
- Covid19, Delirium, Post-traumatic Stress Disorder
- Trial name
- BRAINSTORM (NCT04785157)
- Testing
- serology testing profiles description, immune response characterization, in vivo brain PET-TSPO acquisitions
- Where
- 2 sites in France
- Volunteers
- 7 people
- Sponsor
- University Hospital, Toulouse
COVID-19, Acute Kidney Injury
Applying Artificial Intelligence to Identify Subphenotypes of Acute Kidney Injury in Mexican Patients With Severe COVID-19
The goal of this observational study was to identify subphenotypes of acute kidney injury patients with COVID-19, and the investigators analyzed their impact on mortality.
- Trial name
- IA-COVAKI (NCT06471101)
- Testing
- clusters
- Where
- Mexico
- Volunteers
- 2,934 people
- Sponsor
- Instituto Nacional de Enfermedades Respiratorias
SARS-CoV-2, Coronavirus
Personalized Health Education Against the Health Damage of Novel Coronavirus (COVID-19) Outbreak in Hungary
The additional effect of personalized health education compared to general education following the internationally accepted principles will be evaluated in the prevention of the serious course of the novel coronavirus infection.
- Conditions
- SARS-CoV-2, Coronavirus, COVID-19, 2019-nCoV
- Trial name
- PROACTIVE-19 (NCT04321928)
- Testing
- Personalized health education, General health education
- Where
- Hungary
- Volunteers
- 449 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Covid19
Measles Vaccine in HCW
Till now, mortality reports among children below 9 years remains extremely low despite that the incidence of death toll is high and exceeding 50,000 patients among older population, One speculation for lower SARS infectivity is…
- Trial name
- MV-COVID19 (NCT04357028)
- Testing
- Measles-Mumps-Rubella Vaccine
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
2019 Novel Coronavirus Disease
Observational Cohort of COVID-19 Patients in Hubei Province
This study intends to use the relevant case data of COVID-19 in Hubei Province, using big data processing and mining methods to evaluate the effects of clinical indicators, drug use and genes on the clinical prognosis of COVID-19…
- Trial name
- OCCP-HP (NCT05615792)
- Testing
- No intervention
- Where
- China
- Volunteers
- 68,000 people
- Sponsor
- Dao Wen Wang
COVID-19
Immunogenicity and Safety Study of Monovalent Omicron XBB.1.5 Vaccine as a Booster in Adults
The purpose of this study is to assess the immunogenicity and safety of SCB-2023B monovalent Omicron XBB.1.5 vaccine compared to the prototype SCB-2019 vaccine in participants previously vaccinated with 3 doses of inactivated…
- Trial name
- NCT06567457
- Testing
- SCB-2023B vaccine, a monovalent Omicron XBB.1.5 recombinant SARS-CoV-2 trimeric S-protein subunit vaccine for COVID-19, SCB-2019 vaccine, a monovalent wu-hu1 SARS-CoV-2 trimeric S-protein subunit vaccine for COVID-19
- Volunteers
- healthy volunteers welcome
- Sponsor
- Clover Biopharmaceuticals AUS Pty
Post-COVID-19 Syndrome, Dyspnea
Home-Based Respiratory Muscle Strength Training Program for Individuals With Post-COVID-19 Persistent Dyspnea
To evaluate the extent to which a 12-week respiratory rehabilitation program consisting of inspiratory and expiratory breathing exercises compared to expiratory breathing exercises alone will help to improve shortness of breath…
- Trial name
- NCT06091280
- Testing
- Respiratory Muscle Strength Trainers
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of South Florida
COVID19, Pneumonia, Viral
Predictive Models for Intensive Care Admission and Death of COVID-19
To build simple and reliable predictive scores for intensive care admissions and deaths in COVID19 patients. These scores adhere to the TRIPOD (transparent reporting of a multivariable prediction model for individual prognosis or…
- Conditions
- COVID19, Pneumonia, Viral, Inflammatory Response
- Trial name
- NCT04401228
- Testing
- predict admission of covid-19 patients to ICU and death with routine and quickly avalaible clinical, biological and radiological variables?
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Clinique Saint Pierre Ottignies
COVID-19, Vaccines
Effects of Prompt to Bundle COVID-19 Booster and Flu Shot
This randomized controlled trial investigates whether text-based reminders can increase the bivalent COVID-19 booster uptake and whether text-based reminders that mention the opportunity to bundle the COVID-19 booster with the…
- Trial name
- NCT05586165
- Testing
- Reminder to boost protection against COVID-19, Flu Tag Along, COVID-19 Booster & Flu Bundle
- Where
- United States
- Volunteers
- 109,493 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Long COVID-19 Syndrome
Safety and Efficacy of Umbilical Cord Mesenchymal Stem Cell Exosomes in Treating Chronic Cough After COVID-19
This clinical trial aims to evaluate the safety and effectiveness of umbilical cord mesenchymal stem cell (UCMSC)-derived extracellular vesicle nebulization inhalation therapy for the treatment of chronic cough after COVID-19…
- Trial name
- NCT05808400
- Testing
- MSC-derived exosomes
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Huazhong University of Science and Technology
COVID-19
Study on the Safety and Efficacy of Meplazumab for Injection Patients COVID-19
This is a multicenter, randomized, double-blind, placebo-controlled, add-on Phase III clinical study. Based on the "Diagnosis and Treatment Protocol for COVID-19 Pneumonia (Trial 10th edition)" and according to the results of…
- Trial name
- NCT05679492
- Testing
- Meplazumab foe injection, Normal saline
- Where
- China
- Sponsor
- Jiangsu Pacific Meinuoke Bio Pharmaceutical Co Ltd
Covid19, Pediatric Psychiatric Disorder
CARTOON: CoronAviRus (COVID-19) educaTional prOgram fOr childreN
Our study aims to investigate whether our CoronAviRus educaTional prOgram fOr children (CARTOON) facilitates the adherence to hygiene measures and is feasible to dispel fear in preschool children (3-6 years old) during the…
- Conditions
- Covid19, Pediatric Psychiatric Disorder, Psychological Stress
- Trial name
- CARTOON (NCT04724616)
- Testing
- Educational Program (CARTOON)
- Where
- Austria
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
ARDS, Human, Covid19
Associations Between COVID-19 ARDS Treatment, Clinical Trajectories and Liberation From Mechanical Ventilator - an Analysis of the NorthCARDS Dataset
The mortality rates associated with COVID-19 related ARDS (COVIDARDS) have varied from observational reports from around the world.
- Trial name
- NorthCARDS (NCT04729075)
- Testing
- ARDS and COVID19 treatments
- Where
- United States
- Volunteers
- 1,800 people
- Sponsor
- Northwell Health
Covid19
Involvement of Polymorphonuclear Neutrophils and Platelets in Severe Form of COVID-19
The main objective is to quantify the population of reverse migrating neutrophils in patients with COVID-19.
- Trial name
- NeutroVID (NCT04930757)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
COVID-19
Aerosol Combination Therapy of All-trans Retinoic Acid and Isotretinoin as A Novel Treatment for Inducing Neutralizing Antibodies in COVID -19 Infected Patients Better Than Vaccine : An Innovative Treatment
Aerosol Combination therapy of All-trans retinoic acid and Isotretinoin as A novel Treatment for Inducing Neutralizing Antibodies in COVID -19 Infected Patients better than vaccine : An innovative Treatment Mahmoud…
- Trial name
- Antibodies (NCT04396067)
- Testing
- Aerosolized 13 cis retinoic acid, Aerosolized All trans retinoic acid
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Covid-19, Cardiovascular Risk Factor
Telemedicine in Outpatient Covid-19 Patients
Covid-19, a commonly severe respiratory tract infection caused by the SARS-CoV2 Coronavirus, poses an increasing threat to individual health and health care systems.
- Trial name
- COVID-SMART (NCT04471636)
- Testing
- Withings ScanWatch
- Where
- Germany
- Volunteers
- 607 people
- Sponsor
- Ludwig-Maximilians - University of Munich
COVID 19
BromhexIne And Spironolactone For CoronаVirUs Infection Requiring HospiTalization
Patients with mild and severe COVID 19 will be randomized 1:1 into two groups: experimental, which will get bromhexine and spironolactone, and control. Patients will get investigated therapy for ten days.
- Trial name
- BISCUIT (NCT04424134)
- Testing
- Bromhexine and Spironolactone, Base therapy
- Where
- Russia
- Volunteers
- 80 people
- Sponsor
- Lomonosov Moscow State University Medical Research and Educational Center
Emergencies
Evaluation of the COVID-19 Infection Response in Patients Admitted to the Emergency Department for Dyspnea
This research aims to improve our knowledge of the epidemiology of patients consulting in the COvid-19 Possible REspiratory Units (RECOP unit). Indeed, the epidemic linked to COVID-19 affects France and impacts its health system.
- Trial name
- EPRICOD (NCT04422587)
- Testing
- RECOP unit patient
- Where
- France
- Volunteers
- 1,860 people
- Sponsor
- University Hospital, Toulouse
SARS-CoV-2, COVID-19
National Survey of Symptoms of People Aged 70 and Overs Diagnosed With COVID-19
Cross-sectional study based on a French national survey aimed to described and identify the most frequent symptoms of COVID-19 older patients.
- Trial name
- COVID19PUGG2 (NCT04343781)
- Testing
- observation
- Where
- France
- Volunteers
- 353 people
- Sponsor
- University Hospital, Angers
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