Clinical trials: Covid-19 Pneumonia
Healthy
A Trial to Learn if a COVID-19 Therapeutic is Safe and Well Tolerated, and How it Works in the Body of Healthy Adult Participants
The primary objective of the study is to evaluate the safety and tolerability of REGN14284 in healthy participants, as measured by all treatment-emergent adverse events (TEAEs) and treatment-emergent serious adverse events…
- Trial name
- NCT05505448
- Testing
- REGN14284
- Where
- Belgium
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Regeneron Pharmaceuticals
Disseminated Intravascular Coagulation, Critical Illness
Thrombomodulin-modified Thrombin Generation Assay (TGA-TM) in Patients With Critical Infections
Inflammation and abnormalities in laboratory coagulation tests are inseparably tied. For example, coagulation abnormalities are nearly universal in septic patients.
- Conditions
- Disseminated Intravascular Coagulation, Critical Illness, Sars-CoV2, Viral Infection
- Trial name
- NCT04356144
- Testing
- Thrombin Generation Assay (TGA), Thrombomodulin Modified Thrombin Generation Assay (TGA-TM)
- Where
- Austria
- Volunteers
- 58 people
- Sponsor
- Medical University of Vienna
Covid19
Clinical Trial Evaluating the Efficacy and Safety of Favipiravir in Moderate to Severe COVID-19 Patients
This is a prospective, interventional, multi-centre, phase III, randomized, double blind, placebo-controlled, parallel design trial to evaluate the efficacy, safety and tolerability of favipiravir as adjunct ('add on') to…
- Trial name
- NCT04529499
- Testing
- AVIGAN
- Where
- 2 sites in Kuwait
- Volunteers
- 353 people
- Sponsor
- Dr. Reddy's Laboratories Limited
COVID-19, SAR-CoV-2
Long-term Effects of COVID-19
The purpose of this study is to measure, monitor, and analyze long term effects of SARS-CoV-2. The main purpose is to assess the post-hospitalization outcomes of patients who were diagnosed with SAR-CoV-2 by comparing to patients…
- Trial name
- NCT05220514
- Testing
- (R)-1-(2-chlorophenyl)- N-[11C] ([11C] PK11195), 2-(4-[11C]methylamino phenyl)-6-hydroxybenzothiazole (11C]6-OH-BTA-1 or [11C]PIB)
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- Mayo Clinic
COVID-19
Assessment of Incidence of SARS-CoV-2 Infection and COVID-19 in Brazil (AVISA)
This is an observational study, meaning that no interventions is tested, to determine incidence of SARS-CoV-2 infection and COVID-19 in different clinical sites in Brazil in several age groups.
- Trial name
- AVISA (NCT04355338)
- Where
- 11 sites in Brazil
- Volunteers
- 3,520 people, healthy volunteers welcome
- Sponsor
- Butantan Institute
Acupuncture, Covid-19 Omicron
Acupuncture as an Adjunctive Therapy for Covid-19 Omicron Randomised Controlled Trial in Patients With Moderate/Severe Pneumonia
At present, China is facing the first wave of COVID-19 epidemic after the liberalization. The infection rate has exceeded 50% in most areas, and even exceeded 80% in some cities.
- Conditions
- Acupuncture, Covid-19 Omicron, Pulmonary Function
- Trial name
- ZCFZZLXGBDFYHZ (NCT05692258)
- Testing
- Acupuncture
- Where
- China
- Volunteers
- 146 people
- Sponsor
- The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine
Type2 Diabetes, Covid19
Advancing DSME/S and COVID-19 Prevention and Protection Through "emPOWERed to Change" Program
African Americans (AA)/People of Color (POC) are disproportionately impacted by COVID-19 to an extent not observed in other racial/ethnic subgroups.
- Trial name
- NCT04993326
- Testing
- emPOWERed To Change Program
- Sponsor
- Charles Drew University of Medicine and Science
Covid19
Prevalence of Thrombosis in COVID-Patients
Examination of the prevalence of thrombosis in COVID-patients, especially in an out-patient setting. Assessment by duplex sonography. If thrombosis is detected, we will correlate it with immunity status.
- Trial name
- NCT04615026
- Testing
- duplex sonography
- Where
- Germany
- Volunteers
- 525 people
- Sponsor
- University Hospital Augsburg
Covid19, SARS-CoV Infection
COVID-FIS: Pilot in COVID-19 (SARS-CoV-2) of Fisetin in Older Adults in Nursing Homes
The purpose of this study is to test whether Fisetin, a senolytic drug, can assist in preventing an increase in the disease's progression and alleviate complications of coronavirus due to an excessive inflammatory reaction.
- Trial name
- COVID-FIS (NCT04537299)
- Testing
- Fisetin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
SARS-CoV-2 Infection
Asymptomatic COVID-19 Trial
The coronavirus disease-2019 (COVID-19) is spreading throughout the United States. While there are no known therapies to treat those who have become sick, there have been some reports that a medication currently used to treat…
- Trial name
- ACT (NCT04374552)
- Testing
- Hydroxychloroquine sulfate &Azithromycin
- Where
- United States
- Sponsor
- Rutgers, The State University of New Jersey
Post-acute Covid-19 Syndrome
Homeopathic Treatment of Post-acute COVID-19 Syndrome
To determine whether an individually prescribed homeopathic medicine has an effect greater than a placebo and is a viable treatment option to improve fatigue and quality of life for patients suffering from the symptoms of…
- Trial name
- NCT05104749
- Testing
- Homeopathic Medication
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Southwest College of Naturopathic Medicine
Covid19, Viral Pneumonia Human Coronavirus
Methylprednisolone vs. Dexamethasone in COVID-19 Pneumonia (MEDEAS RCT)
Low-dose glucocorticoid treatment is the only intervention shown to significantly reduce mortality in cases of COVID-19 pneumonia requiring oxygen supplementation or ventilatory support.
- Conditions
- Covid19, Viral Pneumonia Human Coronavirus, Severe Acute Respiratory Syndrome
- Trial name
- MEDEAS (NCT04636671)
- Testing
- Methylprednisolone, Dexamethasone
- Where
- Italy
- Volunteers
- 690 people
- Sponsor
- University of Trieste
COVID-19
Ivermectin for Severe COVID-19 Management
In this multicenter study; it was aimed to investigate the effectiveness and safety of ivermectin use in the treatment of patients with severe COVID-19 pneumonia that have no mutations which alter ivermectin metabolism and cause…
- Trial name
- NCT04646109
- Testing
- Ivermectin
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
COVID-19
Therapeutic Plasmapheresis in Critically Ill Adult Patients With COVID-19 Confirmed Diagnosis
Introduction: The SARS-CoV-2 outbreak has left more than two million infected worldwide in the first four months of COVID-19 epidemic.
- Trial name
- PLASMA (NCT04480632)
- Testing
- Convalescent plasma
- Where
- Colombia
- Volunteers
- 44 people
- Sponsor
- Fundación Cardiovascular de Colombia
Coronavirus Disease 2019 (COVID-19)
Increased Risk of Severe Coronavirus Disease 2019 in Patients With Vitamin D Deficiency
In this prospective observational study we aim to study the association of vitamin D deficiency with adverse clinical outcomes in patients infected with Coronavirus disease 2019
- Trial name
- COVIT-D (NCT04403932)
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Hospital San Carlos, Madrid
COVID-19
Evaluating Emetine for Viral Outbreaks (EVOLVE)
The goal of this clinical trial (phase 2/phase 3) is to evaluate the efficacy and safety of emetine administered orally for symptomatic Covid-19 patients in patients ages 30 years and above.
- Trial name
- EVOLVE (NCT05889793)
- Testing
- Emetine Hydrochloride
- Where
- 2 sites in United States, Nepal
- Volunteers
- 4 people
- Sponsor
- Johns Hopkins University
COVID-19
Cannabidiol Treatment for Severe and Critical Coronavirus (COVID-19) Pulmonary Infection
Current management of COVID-19 (coronavirus) is mainly supportive, and respiratory failure from acute respiratory distress syndrome (ARDS) is the leading cause of mortality.
- Trial name
- NCT04731116
- Testing
- Cannabidiol
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Rabin Medical Center
COVID-19
Thorax Computed Tomography Severity Score and Outcome in COVID-19 Patients
The most common thorax Computed tomography (CT) findings are multifocal ground-glass opacities and peripheral consolidation in patients with COVID-19.
- Trial name
- NCT04424849
- Testing
- CT-Scan
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Tepecik Training and Research Hospital
Covid-19, Coronavirus Infection
Physical Activity Level, Stress Level, Sleep Quality in Pregnant Women During Covid-19 Quarantine
We hypothesized: During the COVID-19 pandemic, the sleep quality of pregnant women decreases. During the COVID-19 epidemic, the stress level of pregnant women increases.
- Conditions
- Covid-19, Coronavirus Infection, Pregnancy Related
- Trial name
- NCT04336787
- Testing
- Survey
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul Kültür University
Long COVID, PASC Post Acute Sequelae of COVID 19
Brain Stimulation in Long COVID
Cognitive problems and severe fatigue are two frequently occurring symptoms in long COVID, also known as Post-Covid Condition or Post-Acute Sequelae of COVID-19 (PASC), and their causes are currently unknown.
- Conditions
- Long COVID, PASC Post Acute Sequelae of COVID 19, Post COVID-19 Condition (PCC)
- Trial name
- MALIBU (NCT07278206)
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- Netherlands
- Volunteers
- 66 people
- Sponsor
- Amsterdam UMC, location VUmc
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