Clinical trials: Covid-19 Pneumonia
Covid19, Acute Respiratory Distress Syndrome
The MEseNchymal coviD-19 Trial: MSCs in Adults With Respiratory Failure Due to COVID-19 or Another Underlying Cause
This is a pilot, multi-centre, open-label randomised controlled study to assess the early efficacy of intravenous (IV) administration of CYP-001 in adults admitted to an intensive care unit (ICU) with respiratory failure
- Trial name
- MEND (NCT04537351)
- Testing
- CYP-001
- Where
- 5 sites in Australia
- Volunteers
- 14 people
- Sponsor
- Cynata Therapeutics Limited
Covid19
Electrocardiographic QRS Axis Shift ,Rotation and COVİD-19
In patients with coronavirus disease (COVID-19), severe dyspnea is the most dramatic complication.Severe respiratory difficulties may include electrocardiographic frontal QRS axis rightward shift (Rws) and clockwise rotation…
- Trial name
- NCT04698083
- Testing
- Electrocardiography ,Tomographic imaging
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Ankara Education and Research Hospital
Surgical Procedures, Operative, COVID-19
The Impact of the COVID-19 Pandemic on the Patient in Need of an Intervention
Mixed-method observational study: the impact of pandemic related changes in healthcare on quality of life and experiences with healthcare in Dutch patients undergoing surgery or another intervention during the covid pandemic…
- Conditions
- Surgical Procedures, Operative, COVID-19, SARS-CoV-2
- Trial name
- COVID Surg III (NCT05736822)
- Where
- Netherlands
- Volunteers
- 5,277 people
- Sponsor
- University Medical Center Groningen
COVID-19 Pneumonia, Impaired Respiratory Function
Study of Efficacy and Safety of MAS825 in Patients With COVID-19
This clinical study was designed to assess the efficacy and safety of MAS825 for the treatment of severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) infected patients with coronavirus disease 2019 (COVID-19) pneumonia…
- Trial name
- MAS-COVID (NCT04382651)
- Testing
- MAS825, Standard of Care (SoC)
- Where
- 21 sites in United States
- Volunteers
- 140 people
- Sponsor
- Novartis Pharmaceuticals
Sars-CoV2, COVID19
A Study of Hydroxychloroquine and Zinc in the Prevention of COVID-19 Infection in Military Healthcare Workers
A multicenter randomized clinical trial aiming to assess the efficacy of hydroxychloroquine associated to Zinc compared to hydroxychloroquine, in the prevention of Military Health Professionals Exposed to SARS CoV2 in Tunisia
- Trial name
- COVID-Milit (NCT04377646)
- Testing
- Hydroxychloroquine, Zinc
- Where
- Tunisia
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- Military Hospital of Tunis
SARS-CoV-2 Infection
Phase 3 Study of S-217622 in Prevention of Symptomatic SARS-CoV-2 Infection
The purpose of this study is to measure the proportion of participants who are infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (positive reverse transcription polymerase chain reaction [RT-PCR] test)…
- Trial name
- SCORPIO-PEP (NCT05897541)
- Testing
- S-217622
- Where
- 178 sites in United States, Argentina and 3 more
- Volunteers
- 3,701 people, healthy volunteers welcome
- Sponsor
- Shionogi
Myeloproliferative Disease, COVID - 19
Autoantibodies Against Type I Interferon in Patients Affected With Ph-negative Myeloproliferative Neoplasms (MPN-IFN Study)
The classic Ph-negative myeloproliferative neoplasms (MPN) are a group of clonal hematopoietic disorders caused by a dysregulated JAK/STAT signal transduction because of acquired somatic mutations of JAK2, CALR or MPL genes.
- Trial name
- NCT07204366
- Where
- Italy
- Volunteers
- 219 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Covid19, Cancer
Serologic Response to the SARS-CoV-2 (COVID-19) MRNA-1273 Vaccine in Select Subsets of Oncology Patients
To explore the immune response to the COVID-19 vaccine in cancer patients and compare to the general population.
- Trial name
- NCT04854980
- Testing
- Blood Sample
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Rochester
Cerebral Palsy, Covid19
The Effect of Pandemic on Children With Cerebral Palsy
Cerebral Palsy (CP), is the most common cause of physical disability that begins in childhood and lasts throughout life, affecting 1 in 500 newborns, with an estimated prevalence of 17 million worldwide.
- Trial name
- NCT04970927
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Sevda Adar
Post COVID-19 Syndrome, Functional Inspiratory Muscle Training
Effectiveness of Functional Respiratory Muscle Training in Post-COVID-19 Syndrome
This study aims to investigate the effects of core stabilization exercises and functional inspiratory muscle training (IMT) on various physiological and psychological parameters in individuals with post-COVID-19 syndrome.
- Conditions
- Post COVID-19 Syndrome, Functional Inspiratory Muscle Training, Core Stabilization
- Trial name
- NCT07051954
- Testing
- Core Stabilization, Functional Inspiratory Muscle Training (IMT)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Hacettepe University
COVID-19 Pneumonia, Tocilizumab
Tocilizumab in Covid-19 Penumonia in Buenos Aires City
We conducted a retrospective observational study of adult participants receiving only SOC (dexamethasone 8 mg or its equivalent plus oxygen, HNFO or eventual IMV) versus participants receiving SOC plus TCZ (8mg/kg as a single…
- Trial name
- NCT05057962
- Where
- Argentina
- Volunteers
- 100 people
- Sponsor
- Sanatorio Finochietto
COVID-19 (Coronavirus Disease 2019)
Physiological Finding in Management of COVID 19 Patients
This study utilizes physiological indicators of COVID-19 patients as tools for assessing, tracking, worsening, and improving the clinical symptoms of COVID-19 patients.
- Trial name
- COVID-19 (NCT07504341)
- Testing
- physiological parameters
- Where
- 2 sites in Taiwan
- Volunteers
- 15,000 people
- Sponsor
- St. Martin De Porress Hospital
SARS-CoV-2, Seasonal Influenza
A Study of Modified mRNA Vaccines in Healthy Adults
The main goal of this study is to evaluate the safety, reactogenicity, and immunogenicity of study vaccines.
- Conditions
- SARS-CoV-2, Seasonal Influenza, Respiratory Syncytial Virus, Cytomegalovirus
- Trial name
- NCT05397223
- Testing
- mRNA-1273, mRNA-1010, mRNA-1345
- Where
- 8 sites in United States
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- ModernaTX, Inc.
COVID-19
Impact of COVID-19 on Marshallese Communities in the U.S.
Marshallese adults in the U.S. will complete an online or telephone survey. This survey will collect data describing the impact of COVID-19 on Marshallese communities.
- Trial name
- NCT04474496
- Testing
- Assessing the impact of COVID-19
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Arkansas
Economic Burden
Covid -19 Pandemic: Economic Burden on Patients Operated for Traumatic Close Fractures
Covid-19 has adversely impacted the health care organizations by over burdening with Covid patients and suspending the elective surgeries and clinics A single center retrospective study was conducted to quantify losses due to…
- Trial name
- NCT04482205
- Where
- Pakistan
- Volunteers
- 840 people
- Sponsor
- Aga Khan University
Healthy
Convalescent Plasma Donor Vaccine Study An Observational Antibody Level Study.
There is a need to understand antibody responses following SARS-COV-2 infection and subsequent vaccination.
- Trial name
- C-VELVET (NCT04954937)
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- NHS Blood and Transplant
COVID-19, Pregnancy Related
Evaluation of Hand Grip Strength in Pregnant COVID-19 Patients
It was presented as a cross-sectional, single-center, retrospective case series. Pregnant women with a positive Polymerase Chain Reaction (PCR) diagnosis of Covid 19 were included in the study.
- Trial name
- NCT05970874
- Testing
- Hand grip strength measureme
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people
- Sponsor
- Karaman Training and Research Hospital
COVID-19, Children, Only
Water and Land-based Exercise for Children With Post COVID-19 Condition
The latest data indicate that post COVID-19 condition is frequent in children and adolescents, with the most common symptoms being fatigue, shortness of breath, exercise intolerance and weakness.
- Conditions
- COVID-19, Children, Only, Lung Function Decreased, Quality of Life
- Trial name
- postcovidkids (NCT05216549)
- Testing
- Water-based exercise, Land-based exercise
- Where
- Poland
- Volunteers
- 75 people
- Sponsor
- Józef Piłsudski University of Physical Education
COVID-19, BCG Vaccination
Outcome of COVID-19 Cases Based on Tuberculin Test: Can Previous BCG Alter the Prognosis?
There is no evidence that the Bacille Calmette-Guérin vaccine (BCG) protects people against infection with COVID-19 virus. Two clinical trials addressing this question are underway, and WHO will evaluate the evidence when it is…
- Trial name
- NCT04347876
- Testing
- Tuberculin test
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Covid19
A Wearable, Battery-free Screening System for SARS-CoV-2, the Virus Causing COVID-19 Infection
The corona virus disease (COVID) pandemic has highlighted the importance of rapid, readily available screeners and diagnostics to identify infected individuals.
- Trial name
- NCT04807075
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Nebraska
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