Clinical trials: Covid-19 Pneumonia
Covid19, SARS-CoV Infection
A Phase III Clinical Trial of the Immunogenicity and Safety of the Gam-COVID-Vac Vaccine Against COVID-19 in the UAE
This study is randomized, double-blind (blinded for the trial subject and the study physician), placebo-controlled trial in the parallel assignment of the immunogenicity, and safety of the Gam-COVID-Vac combined vector vaccine…
- Trial name
- SPUTNIK-UAE (NCT04656613)
- Testing
- Gam-COVID-Vac
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation
Eating Disorders, COVID 19
Containment Measures and Eating Disorders
Since March 17, 2020, the French government has implemented national containment measures due to the COVID-19 epidemic. Quarantine is an unpleasant experience : Separation from relatives, loss of liberty, concern about the…
- Trial name
- COVITA (NCT04492189)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Montpellier
COVID-19
Phase I Clinical Trial of Recombinant SARS-CoV-2 Spike Protein Vaccine (CHO Cell) for the Prevention of COVID-19
The purpose of this double-blind, randomized, controlled study is to assess safety, reactogenicity, and preliminary immunogenicity of 202-CoV at multiple dose levels, administered as 2 injections (i.m) at 28 days apart in adult…
- Trial name
- NCT04982068
- Testing
- 202-CoV low adjuvant dose, 202-CoV low antigen dose, 202-CoV standard dose
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Shanghai Zerun Biotechnology Co.,Ltd
SARS-COV 2, Covid19
Pilot Study to Evaluate the Safety, Tolerability, and Efficacy of 5-ALA-Phosphate + SFC as an Immune System Enhancer Along With Vaccination Against COVID-19
This is an open-label, two arm interventional exploratory study to evaluate the safety and efficacy of 5-ALA-Phosphate-SFC during the vaccination of subjects against SARS-CoV-2 (COVID-19) virus infection to define the safety and…
- Trial name
- NCT04854876
- Testing
- 5-ALA-Phosphate + SFC (5-ALA+SFC)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Royal College of Surgeons in Ireland - Medical University of Bahrain
Covid19, Influenza
Wide Scale Monitoring for Acute Respiratory Infection Using a Mobile-Based Study Platform
This is a prospective observational study using a mobile study platform (app) that is designed for use on Android phones. Study participants will provide baseline demographic and medical information and report symptoms of…
- Conditions
- Covid19, Influenza, Respiratory Tract Infections, Acute Respiratory Tract Infection
- Trial name
- NCT04663776
- Where
- United States
- Volunteers
- 16,000 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
COVID-19
Postural Changes and Severe COVID-19
COVID-19 remains a widespread global epidemic, increasing morbidity, mortality, healthcare resource consumption, and socio-economic burden on patients worldwide.
- Trial name
- NCT05679440
- Testing
- Postural interventions based on pulmonary imaging
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
COVID19
Association of Comorbidities With COVID19
Association of Comorbidities with unfavorable COVID19 outcomes as admission to intensive care, invasive ventilation or death.
- Trial name
- NCT04459390
- Testing
- realtime PCR
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Long COVID, Multiple Chronic Conditions
The Impact of Long COVID on People Living With Pre-existing LTC
The goal of this observational study is to learn about the impact of long COVID on people who have multiple (two or more) pre-existing long-term conditions (such as diabetes and asthma).
- Trial name
- NCT06223997
- Volunteers
- 20 people
- Sponsor
- University of Leicester
Post-acute Sequelae of COVID-19, Long COVID
SARS-CoV-2 and Herpesvirus Inhibition for Ending Long COVID Dysfunction
The purpose of this research study is to test if the combination of three drugs, valacyclovir, celecoxib, and Paxlovid will decrease the symptoms of Long COVID in adults compared to a placebo (this does not contain the…
- Trial name
- SHIELD (NCT07597902)
- Testing
- Valacyclovir, Celecoxib, Paxlovid
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Covid19
Safety of Ascending Doses of Niclosamide (UNI911 INHALATION) in Healthy Volunteers
This is a Phase 1 Randomized, Double-Blind, Parallel Group, Placebo-Controlled Study to Assess the Safety of Ascending Doses of UNI911 INHALATION in Healthy Volunteers in Preparation for Evaluation in Adults with COVID-19
- Trial name
- NCT04576312
- Testing
- UNI911 inhalation 1% and intranasal spray 1%
- Where
- Denmark
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- UNION therapeutics
COVID-19
Crowdsourcing an Open COVID-19 Imaging Repository for AI Research
The objectives of this project are to (1) assemble a crowdsourced, de-identified radiographic repository; and (2) train and validate existing COVID-NET deep learning diagnostic models.
- Trial name
- NCT05384912
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
COVID-19
Efficacy and Safety Study of Nitazoxanide (NTX) in the Treatment of Patients With SARS-CoV-2 Virus Infection (COVID-19)
Evaluation of the efficacy and safety of NTX in adult patients (≥18 years and <60 years), with SARS-CoV-2 infection with mild symptoms of COVID-19, compared to a placebo control arm.
- Trial name
- NCT04463264
- Testing
- Nitazoxanide
- Where
- Argentina
- Volunteers
- 135 people
- Sponsor
- Laboratorios Roemmers S.A.I.C.F.
SARS-CoV-2 Infection
A COVID-19 Study to Evaluate Safety and PK of COVID-HIG Administered Through IM, SC, or IV Routes to SARS-CoV-2 Uninfected Adults
The primary objectives of this open-label trial were to evaluate the safety and pharmacokinetics (PK) of Anti-SARS-CoV-2 Immunoglobulin (Human) Investigational Product (COVID-HIG) administered intramuscularly (IM), subcutaneously…
- Trial name
- NCT05142306
- Testing
- COVID-HIG
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Emergent BioSolutions
Covid19
Pilot Study to Detect SARS-CoV-2 Virus in Sperm
This is a prospective study involving 50 patients, with acute SARS-CoV-2 infection and a positive RNA detection. Men will give semen, saliva, urine and blood specimens following RT-PCR diagnosis and 15, 30, 60 and 90 days after.
- Trial name
- COVSPERM (NCT04584593)
- Testing
- Sample
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Toulouse
SARS Virus
Study to Evaluate the Safety and Efficacy of XAV-19 in Patients With COVID-19 Induced Moderate Pneumonia
Early inhibition of entry and replication of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a very promising therapeutic approach.
- Trial name
- POLYCOR (NCT04453384)
- Testing
- XAV-19
- Where
- 34 sites in France, Martinique and 1 more
- Volunteers
- 416 people
- Sponsor
- Nantes University Hospital
Covid19
Antibiotic Misuse During COVID-19 Pandemic
Evaluating the important role of the community pharmacists in pandemics like covid-19 and to find whether there was a misuse of antibiotics during the pandemic or not and to define the reasons behind this misuse if any present.
- Trial name
- NCT04553055
- Testing
- online questionnaires
- Where
- Egypt
- Volunteers
- 413 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Covid19
Persistence of Neutralizing Antibodies 6 and 12 Months After a Covid-19
Covid-19 is associated with the onset of anti-SARS-CoV-2 antibodies; in a majority of patients, neutralizing antibodies are detected. However, the long-term persistence of such protective antibodies is not known.
- Trial name
- PANCOLIN (NCT04543006)
- Testing
- serology
- Volunteers
- 170 people
- Sponsor
- University Hospital, Grenoble
COVID-19, Influenza A
Clinical Evaluation of the Panbio™ COVID-19/Flu A&B Rapid Panel Professional Use Device and the Panbio™ COVID-19/Flu A&B Rapid Panel Self-Test Device
This study is designed as an international prospective, multicentric, clinical study to investigate the performance and usability of the Panbio™ COVID-19/Flu A\&B Rapid Panel Professional Use and Self- Test devices for the…
- Conditions
- COVID-19, Influenza A, Influenza Type B
- Trial name
- NCT05715515
- Testing
- Panbio™
- Where
- United States
- Volunteers
- 903 people
- Sponsor
- Abbott Rapid Dx
COVID-19
COVID-19 Vaccine Hesitancy Counseling Intervention for Pharmacists: A Stepped-Wedge Trial
The goal of this clinical trial is to test if virtual facilitation (e.g., video coaching) increases rural pharmacists' ability to implement COVID-19 vaccine hesitancy counseling when compared to a "standard" implementation…
- Trial name
- NCT06547814
- Testing
- Standard implementation webinar and online training, Virtual facilitation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of North Carolina, Chapel Hill
Surveys and Questionnaires
Stress Factors and Vaccine Attitudes Among Dental Students During COVID-19
Background: The aim of this study is to investigate the impact of the COVID-19 pandemic on the education of dental students in Turkey, the reasons that affect the psychological attitudes of students towards this disease, stress…
- Trial name
- NCT05171933
- Testing
- Survey
- Where
- Turkey (Türkiye)
- Volunteers
- 579 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
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