Clinical trials: Covid-19 Pneumonia
SARS-CoV-2
A Study to Evaluate Safety, Reactogenicity, and Immunogenicity of mRNA-1283 and mRNA-1273 Vaccines in Healthy Adults Between 18 Years and 55 Years of Age to Prevent COVID-19
The primary goal for this study is to evaluate the safety and reactogenicity of 3 dose levels of mRNA-1283 and 1 dose level of mRNA-1273 vaccine given to healthy adults in 2 doses, 28 days apart, and 1 dose level of mRNA-1283…
- Trial name
- NCT04813796
- Testing
- mRNA-1283, mRNA-1273
- Where
- 5 sites in United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- ModernaTX, Inc.
COVID-19
A Phase I/II Study of GLB-COV2-043 as a COVID-19 Vaccine Booster
The scope of this Phase I/II study is to determine whether GLB-COV2-043 is a promising booster vaccine candidate component for adult participants who have received the 2-dose priming course of the mRNA BNT162b2 vaccine against…
- Trial name
- NCT05602961
- Testing
- GLB-COV2-043, BNT162b2/COMIRNATY®
- Volunteers
- healthy volunteers welcome
- Sponsor
- GreenLight Biosciences, Inc.
Covid19
The Effectiveness of ACB-IP 1.0 Convalescent Plasma in COVID-19 Infection
Pathogen-free, concentrated, pooled convalescent plasma has higher SARS-CoV2 antibody titers and neutralizing antibody activities, without requiring blood group compatibility that allows patient accessibility in a shorter time…
- Trial name
- NCT04769245
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Acibadem University
Covid19, Cancer
A Study on the Immune-response to COVID-19 Vaccination in Cancer Patients - the IOSI-COVID-19-001 Study
This is a single centre prospective observational study to assess the immune response to SARS-CoV-2 vaccines in cancer patients receiving active treatment or in follow-up at the IOSI and in non-cancer patients (age and gender…
- Trial name
- NCT04800146
- Testing
- Blood sample
- Where
- Switzerland
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Ilaria Colombo
Laughter Yoga, Anxiety
The Effect of Laughter Therapy on Students in the COVID-19 Pandemic
This study was designed as a randomized controlled, pre-test-post-test control group in order to determine the effect of laughter therapy on anxiety, life satisfaction and psychological well-being of nursing students.
- Conditions
- Laughter Yoga, Anxiety, Life Satisfaction, Psychological Well-being
- Trial name
- NCT04786483
- Testing
- Laughter Theraphy
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Diabetes Mellitus, Type 1
Anti-viral Action Against Type 1 Diabetes Autoimmunity
The study GPPAD-05 AVAnT1A is a phase 4 clinical trial intending to enroll 2252 children, who will be randomly assigned to receive COVID-19 vaccination (Comirnaty® 3 μg Omicron XBB.1.5 or new variant Comirnaty vaccines ) or…
- Trial name
- NCT06452654
- Testing
- Comirnaty Injectable Product, Sodium Chloride 0.9% Inj
- Where
- 9 sites in Austria, Belgium and 3 more
- Volunteers
- 2,252 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Covid19, Global Impact
Global Impact of COVID-19 on Pulmonology Special Units
The COVID-19 pandemic is having a profound impact on the world. As of May 18, 2020, there were 4,889,287 confirmed cases and 322,683 deaths globally.
- Conditions
- Covid19, Global Impact, Pulmonology
- Trial name
- NCT04554251
- Testing
- Survey
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Covid19
The Burden of COVID-19 Survivorship
This research study is being done to find out what the longer-term physiological consequences of COVID-19 are, and to determine if exercise therapy can help improve lung function, heart function and overall fitness, and reduce…
- Trial name
- NCT04913129
- Testing
- Exercise Training
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Mayo Clinic
COVID-19
The Efficacy and Safety of Huai er in the Adjuvant Treatment of COVID-19
In December 2019,a new type of pneumonia caused by the coronavirus (COVID-2019) broke out in Wuhan ,China, and spreads quickly to other Chinese cities and 28 countries.
- Trial name
- NCT04291053
- Testing
- Huaier Granule
- Volunteers
- 550 people
- Sponsor
- Tongji Hospital
Coronary Artery Disease
Robot Assisted Percutaneous Cardiovascular Intervention as a Strategy to Reduce or Risk of Intra-Procedure Contamination by COVID-19 and Other Respiratory Viruses
Percutaneous cardiovascular intervention procedures (e.g. coronary angioplasty, peripheral artery angioplasty) must be performed in person, requiring the physical presence of one or more medical, nursing and technical…
- Trial name
- NCT04379453
- Testing
- Robot Assisted Percutaneous Cardiovascular Intervention
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Hospital Israelita Albert Einstein
COVID-19
Treatment of Patients With COVID-19 With Convalescent Plasma
The COVID-19 pandemic has been spreading continuously, and in Brazil, until May 31, 2020, there have been more than 450.000 cases with more than 28.000 deaths, with daily increases.
- Trial name
- COOPCOVID-19 (NCT04415086)
- Testing
- convalescent plasma
- Where
- Brazil
- Volunteers
- 129 people
- Sponsor
- University of Sao Paulo General Hospital
Sepsis
Assessement of Microcirculation With NIRS Predicts Sepsis Development in Patients With Severe Covid-19 Pneumonia
Sepsis and septic shock are among main causes of death in patients with severe Covid-19 pneumonia. A few factors are proven to predict sepsis in these patients.
- Trial name
- NCT06360770
- Where
- Slovenia
- Volunteers
- 35 people
- Sponsor
- General and Teaching Hospital Celje
Pediatric Respiratory Diseases, Asthma
Analysis of Lung Sounds Collected by RESP Biosensor to Support Decision Making in Monitored Hospitalized Pediatric Patients
This observational clinical trial is designed to confirm whether RESP™ Biosensor could be deployed to support clinical decision making in challenging pediatric cases, minimize clinician-to-clinician variability in lung sound…
- Conditions
- Pediatric Respiratory Diseases, Asthma, RSV Infection, COVID-19
- Trial name
- NCT05661422
- Testing
- RESP™ Biosensor
- Where
- United States
- Sponsor
- Strados Labs, Inc.
COVID-19 (Coronavirus Disease 2019)
Levels of Physical Activity After SARS-CoV-2 Infection in Pre-illness Vaccinated and Unvaccinated Greek Adults.
Coronavirus infection has an impact on several aspects of everyday life including the levels of Physical Activity (PA). Investigators wish to (1) detect changes on PA levels in recovered SARS-CoV-2 (COVID-19) adults compared to…
- Trial name
- NCT05787431
- Where
- Greece
- Volunteers
- 2,000 people
- Sponsor
- Emmanouil D. Zacharakis
Pneumonia, Viral, Corona Virus Infection
Convalescent Antibodies Infusion in COVID 19 Patients
The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which originated in Wuhan, China, has become a major concern all over the world.
- Trial name
- NCT04418531
- Testing
- Anti-coronavirus antibodies (immunoglobulins) obtained with DFPP form convalescent patients
- Sponsor
- Piero Luigi Ruggenenti
COVID-19
Randomised Study to Investigate the Effectiveness of Acupuncture for the Relief of Long COVID-19 Related Fatigue
The Covid pandemic has left us with a significant number of people suffering from Long COVID, which is a clinical diagnosis of significant and varying ongoing symptoms at least 12 weeks following COVID-19 infection and…
- Trial name
- ACU-COVID (NCT05212688)
- Testing
- Acupuncture, Active Control
- Where
- United Kingdom
- Volunteers
- 119 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Covid19
Ivermectin Versus Standard Treatment in Mild COVID-19
Rationale: Ivermectin, an inexpensive and available antiparasitic drug, with favourable safety profile, showed inhibitory effect on SARS-CoV2 viral replication in-vitro and in animal models.
- Trial name
- NCT04937569
- Testing
- Ivermectin Tablets
- Where
- Egypt
- Volunteers
- 1,644 people
- Sponsor
- Assiut University
Covid19, Vaccination
Understanding Public Attitudes Towards the COVID-19 Vaccination
The objective of this study is to better understand public attitudes towards coronavirus disease 2019 (COVID-19) vaccination. This understanding will inform the development of community engagement strategies to be used in future…
- Trial name
- CEAL (NCT05023512)
- Testing
- Communication about the COVID-19 vaccination from the Massachusetts Department of Public Health
- Sponsor
- University of Massachusetts, Worcester
COVID-19
Immune Responses to COVID-19 Infection or Vaccination
The overall purpose of this observational cohort study is to characterize COVID-specific immune responses to SARS-CoV-2 exposure or COVID vaccination in a real-world setting.
- Trial name
- NCT05379478
- Testing
- Laboratory assessment of antibody profiles
- Where
- United States
- Volunteers
- 403 people
- Sponsor
- Aditxt, Inc.
COVID-19
ACTIV-5 / Big Effect Trial (BET-C) for the Treatment of COVID-19
This is a platform trial to conduct a series of randomized, double-blind, placebo-controlled trials using common assessments and endpoints in hospitalized adults diagnosed with COVID-19.
- Trial name
- NCT04988035
- Testing
- Danicopan, Remdesivir
- Where
- 39 sites in United States
- Volunteers
- 201 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
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