Clinical trials: Covid19, completed
COVID-19 Respiratory Infection
COVID-19 Novel Molecular Point of Care Diagnostics Evaluation
Point estimates of sensitivity and specificity of molecular POC platforms for SARS-CoV-2, with 95% confidence intervals, using RT-PCR as reference standard.
- Trial name
- NCT06055218
- Where
- 3 sites in Switzerland, Uganda and 1 more
- Volunteers
- 600 people
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
COVID-19
Povidone-Iodine Vs Essential Oil Vs Tap Water Gargling For COVID-19 Patients
The purpose of this study is to assess the ability of regular gargling to eliminate severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the throat and nasopharynx.
- Trial name
- GARGLES (NCT04410159)
- Testing
- Povidone-Iodine, Essential oils, Tap water
- Where
- Malaysia
- Volunteers
- 20 people
- Sponsor
- Universiti Sains Islam Malaysia
COVID-19
Phase 1 Study on Bioavailability, Food Effect, and Drug-Drug Interaction of ALG-097558 Tablets in Healthy Volunteers
The aim of this multi-part Phase 1 study is to evaluate the drug-drug interaction (DDI) potential of ALG-097558 via co-administration with a P-gp substrate (dabigatran) and a CYP3A4 inhibitor/P-gp inhibitor (itraconazole).
- Trial name
- NCT06945276
- Testing
- ALG-097558, Dabigatran, Itraconazole
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
COVID19
Study to Evaluate the Safety and Efficacy of VIRAZOLE® in Hospitalized Adult Participants With Respiratory Distress Due to COVID-19
This study is a Phase 1, open label, non-randomized, two-arm interventional clinical trial to evaluate the safety and efficacy of Virazole® in hospitalized adult patients who have tested positive for COVID-19 and, as a result…
- Trial name
- NCT04551768
- Testing
- 50 mg/mL Virazole, 100 mg/mL Virazole
- Where
- 4 sites in Greece, Mexico
- Volunteers
- 51 people
- Sponsor
- Bausch Health Americas, Inc.
Mental Health Disorder, Depression
Mobile Phone Based Intervention to Protect Mental Health in Healthcare Workers at Frontline Against COVID19
This study aims at evaluating the effectiveness of a mobile phone based intervention to prevent and manage mental health problems in healthcare workers at the frontline against COVID-19 in Spain.
- Conditions
- Mental Health Disorder, Depression, Posttraumatic Stress Disorder, Burnout
- Trial name
- PsyCovid_App (NCT04393818)
- Testing
- Intervention App
- Where
- Spain
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Fundació d'investigació Sanitària de les Illes Balears
Rheumatoid Arthritis
Antimalarial and Covid 19 in Rheumatoid Arthritis
The antimalarial agent hydroxychloroquine(HCQ) have been used widely used for the treatment of rheumatoid arthritis and systemic lupus erythematosus.
- Trial name
- NCT04389320
- Testing
- Hydroxychloroquine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Educational Activities
Facilitating COVID-19 Test for Korean Americans Through Korean Schools in Northern California
In collaboration with Korean Schools of Northern California, the investigators will test if a community-based intervention delivered by lay health educators (LHEs) increases testing uptake among Korean Americans.
- Trial name
- NCT05435482
- Testing
- Education, COVID-19 testing kits, Instruction
- Where
- United States
- Volunteers
- 259 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Respiratory Disease
Screening Patients for a Strategic Shift to Pulmonary Telerehabilitation Because of COVID-19
This study applied the Pulmonary Rehabilitation Adapted Index of Self-Efficacy (PRAISE) on respiratory patients who had their on-going ambulatory Pulmonary Rehabilitation program interrupted due to the COVID-19 outbreak.
- Trial name
- PRAISE@COVID (NCT04388579)
- Testing
- Pulmonary Rehabilitation
- Where
- 3 sites in Portugal
- Volunteers
- 100 people
- Sponsor
- University of Lisbon
Mental Health Wellness 1
Jump Start Plus COVID-19 Support
The purpose of the study is to further develop and examine the Jump Start Plus COVID Support (JS+CS) program, which encourages improved psychosocial functioning by promoting resiliency in childcare centers.
- Trial name
- NCT05445518
- Testing
- Jump Start Plus COVID Support, Healthy Caregivers-Healthy Children (HC2)
- Where
- United States
- Volunteers
- 1,505 people, healthy volunteers welcome
- Sponsor
- University of Miami
COVID-19, Infection Viral
A Phase 1/2 Study to Determine Safety and Immunogenicity of Two COVID 19 Vaccines VB10.2129 (RBD Candidate) and VB10.2210 (T Cell Candidate) Previously Vaccinated in Healthy Adult Volunteers
An open label, dose escalation, and dose expansion study to evaluate the safety, reactogenicity and immunogenicity of two SARS-CoV-2 DNA plasmid vaccine candidates, VB10.2129 (C1) and VB10.2210 (C2).
- Conditions
- COVID-19, Infection Viral, Infections
- Trial name
- NCT05069623
- Testing
- VB10.2129, VB10.2210
- Where
- 2 sites in Norway
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Nykode Therapeutics ASA
COVID-19, Low Triiodothyronine Syndrome
The Impact of Pituitary-thyroid and Pituitary-adrenal Axes Function on COVID-19 Clinical Course.
The main focus of the study is the assessment of hormonal function in the course of COVID-19 infection with special regard for trends predicting clinical events defined as primary endpoints of the study.
- Conditions
- COVID-19, Low Triiodothyronine Syndrome, Adrenal Insufficiency, Subacute Thyroiditis
- Trial name
- ENDO-COVID19 (NCT05070091)
- Where
- 2 sites in Poland
- Volunteers
- 180 people
- Sponsor
- Medical University of Gdansk
Corona Virus Infection
Role of Mega Dose of Vitamin C in Critical COVID-19 Patients
Vitamin C (ascorbic acid) is a water-soluble vitamin having anti-inflammatory, immunomodulatory, anti-oxidative, antithrombotic and antiviral properties.
- Trial name
- NCT04682574
- Testing
- Vitamin C
- Where
- Pakistan
- Volunteers
- 278 people
- Sponsor
- University of Lahore
COVID-19
The siCoV/KK46 Drug Open-safety Study
This is an open-label, dose-escalation phase I study to assess the safety and tolerability of siCoV/KK46 in healthy volunteers. The purpose of this study is to determine the maximum daily dose of siCoV/KK46 as a single agent in…
- Trial name
- NCT05208996
- Testing
- siCoV/KK46
- Where
- Russia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National Research Center - Institute of Immunology Federal Medical-Biological Agency of Russia
COVID-19, Anxiety Syndrome
Prevalence and Risk Factors of Anxiety and Depression Among Policemen During the Health Crisis Linked to COVID-19
To date, there is little international data on depression and anxiety among police officers apart from studies carried out after an attack or natural disaster.
- Conditions
- COVID-19, Anxiety Syndrome, Depression Syndrome, Policemen
- Trial name
- Covid19-Police (NCT06076876)
- Where
- France
- Volunteers
- 600 people
- Sponsor
- University Hospital, Strasbourg, France
Coronavirus Infections
Compassionate Use of Opaganib in Patients With Coronavirus Disease 2019 (COVID-19)
Shaare-Zedek Medical Center is a tertiary academic hospital in Jerusalem, Israel. On March 2020, a dramatic increase in the number of COVID-19 cases were diagnosed in Jerusalem. RedHill Biopharma, Ltd.
- Trial name
- NCT04435106
- Testing
- Opaganib, Standard of Care
- Where
- Israel
- Volunteers
- 23 people
- Sponsor
- Shaare Zedek Medical Center
Covid-19
Exploratory Study to Evaluate the Efficacy of RUTI® Against SARS-COV-2 Infection (COVID-19) in Healthcare Workers
The aim of this study is to explore potential for reduction of incidence and/or morbidity of SARS-CoV-2 infection in healthcare personnel. The study will include a comparison between placebo and RUTI® vaccine in a 2:1 design.
- Trial name
- NCT04903184
- Testing
- RUTI® vaccine
- Where
- 6 sites in Argentina
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- RUTI Immunotherapeutics S.L.
Heparin Overdose of Undetermined Intent, COVID-19
Unfractionated Heparin in COVID-19 and Non-COVID-19 Patients
The majority of ICU patients with COVID-19 show profound activation of coagulation, potentially resulting in thromboembolic events.
- Trial name
- NCT05509647
- Testing
- Unfractionated heparin
- Where
- Netherlands
- Volunteers
- 1,500 people
- Sponsor
- Leiden University Medical Center
Coronavirus
Telephony Or Videophony for Isolated elDerly in Maine-Et-Loire 49 During COVID-19
The current health crisis at COVID-19 is forcing us to profoundly rethink our social organizations, especially towards our most fragile seniors.
- Trial name
- TOVID-49 (NCT04333849)
- Where
- France
- Volunteers
- 132 people
- Sponsor
- University Hospital, Angers
Cystic Fibrosis
Psychosocial Factors and Quality of Life in the Effect of Fear of COVID-19 With Cystic Fibrosis
The purpose of this study; The COVID-19 pandemic is to investigate the effects of COVID-19 fear levels of patients with cystic fibrosis on the psychosocial and quality of life levels of individuals.
- Trial name
- NCT05195216
- Testing
- Survey Form, The Hospital Anxiety and Depression Scale, The Fear of COVID-19 Scale,World Health Organization Quality of Life Scale- Bref Form
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Elif Kabasakal
Thrombosis, Nadroparin
Nadroparin Pharmacokinetics in Different Stages of COVID-19
Objective: The risk of thrombotic complications in critical COVID-19 patients remains extremely high, and multicenter trials failed to prove the survival benefit of escalated doses of low molecular weight heparins (LMWH) in this…
- Conditions
- Thrombosis, Nadroparin, COVID-19, Mechanical Ventilation
- Trial name
- NCT05621915
- Testing
- Nadroparin
- Where
- Poland
- Volunteers
- 43 people
- Sponsor
- Medical University of Lublin
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