Clinical trials: Covid19 Vaccination
Anti-SARS-CoV-2 Antibody Response
Detection and Characterization of Anti-SARS-CoV-2 Salivary Antibodies After COVID-19 Booster Vaccines
The investigators aim to evaluate the ability of a COVID-19 (Coronavirus disease) booster vaccine to induce a salivary antibody response and investigate a possible correlation with the serum antibody response and the cellular…
- Trial name
- CoVVacBoost (NCT05142540)
- Testing
- blood and saliva samples will be taken
- Where
- Austria
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Covid19, Vaccination
COVID-19 Vaccination Take-Up
In this work, the investigators are partnering with Contra Costa Health Services (CCHS), the department of health in Contra Costa County, CA, to measure COVID-19 vaccinations and other COVID-19 related preventive health behaviors…
- Trial name
- NCT04867174
- Testing
- Financial incentives, Convenient scheduling link, Race concordant
- Where
- United States
- Volunteers
- 2,701 people
- Sponsor
- National Bureau of Economic Research, Inc.
Myocardial Injury, COVID-19
Myocardial Injury and Dysfunction Associated With COVID-19 Vaccination
The overall goal of the study is to investigate the characteristics and potential mechanisms responsible for myocardial injury and dysfunction in patients after COVID-19 vaccination.
- Conditions
- Myocardial Injury, COVID-19, Vaccine Reaction
- Trial name
- MIDAVAX (NCT05359250)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Colorado, Denver
SARS-CoV Infection
Convalescent Plasma Therapy for COVID-19 Patients
Passive immunization involves the administration of antibodies against a given agent to a susceptible individual for the purpose of preventing or treating an infectious disease due to that agent.
- Trial name
- NCT04565197
- Testing
- convalescent plasma
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Lahore General Hospital
Vitamin d Deficiency, COVID-19
Risk in Devel Long-COVID in Contracting SARS-CoV-2 Infection After COVID-19 Vaccination in Relation to Vitamin D3 Suppl
The aim of this observational retrospective study is to evaluate the effect of supplementation with cholecalciferol D3 in reducing the risk of: occurence of Long COVID syndrome after acute COVID-19 illness occurence of SARS-CoV-2…
- Conditions
- Vitamin d Deficiency, COVID-19, Long COVID
- Trial name
- LONGVITAVAX2 (NCT06452082)
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- IRCCS San Raffaele
Connective Tissue Diseases, Rare Diseases
ERN ReCONNET Study on COVID-19 Vaccination in Rare and Complex Connective Tissue Disease (VACCINATE)
30 months, multicentre, prospective observational study on adult (>18 years) patients with a diagnosis of rare and complex connective tissue diseases (rCTDs) who will be given the vaccine during the period from January 2021 and…
- Conditions
- Connective Tissue Diseases, Rare Diseases, Rheumatologic Disorder
- Trial name
- VACCINATE (NCT04702295)
- Volunteers
- 250 people
- Sponsor
- University of Pisa
SARS-CoV Infection, COVID-19
COVID19 SARS Vaccinations: Systemic Allergic Reactions to SARS-CoV-2 Vaccinations
Background: Allergic reactions have been reported to occur after vaccination with both the Pfizer-BioNTech COVID-19 Vaccine and Moderna COVID-19 Vaccine.
- Conditions
- SARS-CoV Infection, COVID-19, Allergic Reaction, Mast Cell Disorder
- Trial name
- SARS (NCT04761822)
- Testing
- Moderna COVID-19 Vaccine, Pfizer-BioNTech COVID-19 Vaccine
- Where
- 29 sites in United States
- Volunteers
- 746 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
COVID-19
Engaging Staff to Improve COVID-19 Vaccination Response at Long-Term Care Facilities
The ENSPIRE study is a cluster-randomized comparative effectiveness trial being conducted within long-term care and residential facilities that will test a communication and engagement strategy for increasing COVID-19 booster…
- Trial name
- ENSPIRE (NCT05449418)
- Testing
- Full Intervention, Enhanced Usual Care
- Where
- 2 sites in United States
- Volunteers
- 988 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Covid19
Covid-19 Vaccination in Adolescents and Children
Objectives To assess the reactogenicity, measure the adaptive immune responses and track the long-term immune memory in healthy children and adults as well as pediatric patients receiving the COVID-19 vaccines-BNT162b2…
- Trial name
- COVAC (NCT04800133)
- Testing
- Tozinameran, CoronaVac, CoronaVac, intradermal
- Where
- China
- Volunteers
- 1,018 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
COVID-19, Adult
Immunogenicity of COVID-19 Vaccination in Immunocompromised Patients (Auto-COVID-VACC)
This multicenter, prospective, non-interventional study aims to evaluate data on humoral and cellular immune response generated within the COVID-19 vaccination standard in immunocompromised patients.
- Conditions
- COVID-19, Adult, Immunocompromised Patients
- Trial name
- NCT05597761
- Where
- 3 sites in Germany
- Volunteers
- 49 people
- Sponsor
- Oliver Cornely, MD
Individual Satisfaction, Pain Management
The Effect on Pain and Satisfaction of Two Different Non-Pharmacological Methods Used During Coronavirus (Covid-19) Vaccination
The aim of this study was to determine the effect on pain and satisfaction during the administration of Covid-19 vaccination of two different non-pharmacological methods: squeezing a stress ball and placing Buzzy® on the…
- Trial name
- NCT05514262
- Testing
- The stress ball, The Buzzy® device
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Uludag University
COVID-19, Sars-CoV-2 Infection
Booster Vaccination Against COVID-19
A booster dose of vaccine (Turkovac or CoronaVac) will be administered to subjects who have passed at least 90 days and at most 270 days after the second dose of the first course of CoronaVac vaccine.
- Trial name
- NCT04979949
- Testing
- CoronaVac, Turkovac
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- Health Institutes of Turkey
Covid19
Local and General Immune Response After Coronavirus Disease (COVID-19) Vaccination in Volunteers
This study aims to gain more insight in the immunological characteristics and immune response on a local level (the nose) and systemic level (the blood) of healthy people vaccinated with the current available COVID-19 messenger…
- Trial name
- COVACC2 (NCT04996238)
- Testing
- Blood and nasal fluid sampling before and after COVID-19 vaccination
- Where
- Belgium
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
COVID-19
Reducing COVID-19 Related Hospital Admission in Elderly by BCG Vaccination
Bacillus Calmette-Guérin (BCG) vaccine not only protects against tuberculosis, but has also been shown to induce protection against various infections with a viral aetiology, leading to significant reductions in morbidity and…
- Trial name
- NCT04417335
- Testing
- BCG vaccine
- Where
- 2 sites in Netherlands
- Volunteers
- 2,014 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
COVID-19
Assessment of the Response to the Complete Vaccination Guidelines Against Sars-cov2
Prospective observational single-center study in which the impact of anti-TNF biological treatment on the humoral response after complete vaccination against SARS-COV2 in patients with inflammatory bowel disease is analyzed.
- Trial name
- COVID-19 (NCT05153850)
- Where
- Spain
- Volunteers
- 243 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
COVID-19 Vaccine
SARS-CoV-2 Antibody Response in Children Aged 5-11 Years Following Vaccination Against COVID-19
There are few data on the immunogenicity of the Pfizer-Biontec BNT162b2 vaccine for the prevention of COVID-19 disease and of side effects in children aged 5-11 years.
- Trial name
- NCT05175989
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Immunization
Adjuvant Effect of Physical Exercise on Immune Response to COVID-19 Vaccination and Interactions With Stress
The purpose of this study is to evaluate the extent to which a single session of light to moderate intensity exercise performed within 30 minutes after receiving either the initial dose of COVID-19 mRNA vaccine may modify the…
- Trial name
- NCT05213000
- Testing
- Exercise
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Iowa State University
Coronavirus Disease 2019
Immunogenicity and Safety Evaluation of Recombinant Novel Coronavirus Vaccine (CHO Cells) in Enhancing Immunity
Popular topic: Clinical study on immunogenicity and safety evaluation of sequentially enhanced immunity with recombinant Novel Coronavirus vaccine (CHO cells) Research purpose:Main purpose:To evaluate the immunogenicity of…
- Trial name
- NCT05089045
- Testing
- Recombinant new coronavirus vaccine (CHO cell) group
- Where
- China
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
Acne Vulgaris, Vitamin D Deficiency
Impact of COVID-19 Vaccination on Serum 25-hydroxyvitamin D Level
Vitamin D plays a pivotal but still not well understood role in the immune response to coronavirus disease (COVID-19) infection and vaccination.
- Conditions
- Acne Vulgaris, Vitamin D Deficiency, COVID-19
- Trial name
- NCT05398939
- Testing
- Blood test and skin evaluation
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
COVID-19 Infection, COVID-19 Vaccine
To Explore the Protective Effect of SARS-CoV-2 Vaccination on Cancer Patients Infected With SARS-CoV-2
For tumor patients, the virus antibody titer produced by the SARS-CoV-2 vaccine is often lower than that of normal people in a short period of time, but in the long run, it can significantly reduce the infection rate and fatality…
- Trial name
- NCT05774171
- Testing
- no intervention
- Where
- China
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences