Clinical trials: Covid19- Coronavirus- Sars-cov-2
SARS-CoV Infection, Polymerase Chain Reaction
Self-Collected Saliva Samples Without Viral Transport Media for COVID-19 Testing Via RT-PCR
This is a study that will attempt to validate the process for detecting SARS-CoV-2 (COVID19) on a non-FDA-approved technology using self-collected saliva as the specimen.
- Conditions
- SARS-CoV Infection, Polymerase Chain Reaction, Laboratory Testing
- Trial name
- NCT04604145
- Testing
- SARS-CoV-2 testing on the Eppendorf Thermal Cycler PCR system using self-collected saliva as the specimen
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- David Grant U.S. Air Force Medical Center
COVID-19
Ivermectin for Severe COVID-19 Management
In this multicenter study; it was aimed to investigate the effectiveness and safety of ivermectin use in the treatment of patients with severe COVID-19 pneumonia that have no mutations which alter ivermectin metabolism and cause…
- Trial name
- NCT04646109
- Testing
- Ivermectin
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
COVID-19
COVID-19 Self-testing IMPROVE
The study aims to engage community partners to implement IMPROVE intervention and promote (COVID-19) rapid testing among vulnerable Asian Americans in the Greater Philadelphia Area and New York City
- Trial name
- NCT06576167
- Testing
- IMPROVE
- Where
- United States
- Volunteers
- 1,277 people, healthy volunteers welcome
- Sponsor
- Temple University
SARS-CoV-2 Infection (Asymptomatic), SARS-CoV-2 Infection (Symptomatic)
COVID-19 Progression in End-Stage Kidney Disease
The purpose of this study is to collect genomic and clinical data among a cohort of hemodialysis patients and analyze the association between genetic markers and the development and severity of illness in response to SARS-CoV-2.
- Trial name
- COPE (NCT04495907)
- Where
- 11 sites in United States
- Volunteers
- 412 people
- Sponsor
- Davita Clinical Research
COVID-19
Study of Professional and Individual Factors of Covi-19 and Impact on Return to Work
Started on January 9, 2020 with the announcement of the discovery of a new SARS-CoV-2 coronavirus, the Covid-19 pandemic is responsible as of June 21, 2020 for 160,377 confirmed cases in France, 29,640 deaths and 9,823…
- Trial name
- FP-COVID-19 (NCT05616663)
- Where
- France
- Volunteers
- 639 people
- Sponsor
- University Hospital, Strasbourg, France
covid19
Evaluation of the Efficacy of Mouth Rinses With Commercial Mouthwashes to Decrease Viral Load in Saliva in COVID-19 Patients
As no curative treatment for SARS-CoV-2 is currently available, most public health measures to contain the pandemic are based on preventing the spread of the pathogen.
- Trial name
- NCT05543603
- Testing
- Lacer Clorhexidina Colutorio, Lacer Clorhexidine 0.20% Colutorio, Gingilacer Encías Delicadas Colutorio
- Where
- 4 sites in Spain
- Volunteers
- 48 people
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
SARS-CoV-2
A Study to Evaluate the Immunogenicity and Safety of Omicron Variant Vaccines in Comparison With mRNA-1273 Booster Vaccine for COVID-19
This is a 2-part study to evaluate the immunogenicity, safety, and reactogenicity of mRNA-1273.529 and mRNA-1273.214 administered as a booster dose.
- Trial name
- NCT05249829
- Testing
- mRNA-1273.529, mRNA-1273, mRNA-1273.214
- Where
- 29 sites in United Kingdom
- Volunteers
- 3,548 people, healthy volunteers welcome
- Sponsor
- ModernaTX, Inc.
Covid19
Cardiac Assessment After Covid-19 Disease in Elite Altheltic Population
COVID-19 infection coud induce cardiac injuries. Before returning to sport, cardiac evaluation is recommended by sports federations, based on the precautionary principle and the opinion of expert consensus.
- Trial name
- CADE (NCT04653857)
- Where
- France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Montpellier
Sars-CoV2, Cancer
Prospective Analysis of Morbi-mortality of Patients With Cancers in Active Phase of Treatment Suspected or Diagnosed of a SARS-CoV-2 Infection
National multicentre epidemiological study to describe retrospectively and prospectively the clinical outcomes of patients with a suspected coronavirus infection (either confirmed or not) while receiving a medical treatment for…
- Trial name
- ONCOVID-19 (NCT04363632)
- Where
- 18 sites in France
- Volunteers
- 1,231 people
- Sponsor
- Centre Leon Berard
Long COVID
Acupuncture and Chinese Herbal Medicine for Long COVID
List of the Hypothesis: Primary hypothesis: A flexible acupuncture and Chinese herbal medicine protocol will be feasible, acceptable, and useful for the treatment of long COVID.
- Trial name
- ACUCM-LC (NCT07285707)
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Southern California University of Health Sciences
Long COVID
Non-invasive Treatment for Long COVID (Post COVID-19 Condition) Brain Fog
This study aims to assess the effects of both acute and chronic exposures to hypoxia and hypercapnia in patients with Long COVID syndrome.
- Trial name
- NCT06614309
- Testing
- Acute Progressive Carbon Dioxide, Acute Intermittent Hypoxia, Training: Progressive Carbon Dioxide Ramping
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Mayo Clinic
COVID-19, Sars-CoV2
Detection of SARS-CoV-2 in Semen of COVID-19 Positive Males
The objectives of the study, are to describe detection of SARS-CoV-2 in the semen of COVID-19 positive patients, the duration of positive semen and to investigate the impact on semen quality, thereby providing insights into the…
- Conditions
- COVID-19, Sars-CoV2, Corona Virus Infection, Semen
- Trial name
- COVIDSPERM (NCT04391829)
- Testing
- Ejaculated semen sample
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Universitair Ziekenhuis Brussel
Covid19, Contact Case
Relationship Between Biological Profiles and Clinical Evolutions Within the Same Cluster COVID-19 (COVIDCOLLECT)
The hypothesis is that from a cluster defined by a confirmed positive case of COVID-19 and its contact cases, it is possible to study the different expressions and clinical evolutions of COVID-19 infection and to explore the…
- Trial name
- COVIDCOLLECT (NCT04597736)
- Testing
- Biological collection with nasopharyngeal samples, saliva, blood, stool and urine
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
SARS-CoV-2 Acute Respiratory Disease, Covid19
Pandemic Triage Score in Patients With Known or Suspected Severe Acute Respiratory Syndrome (SARS) CoronaVirus (CoV) 2 Infection
During this pandemic period, the goal of the health care system is to optimize the use of intensive care services for patients infected with SARS-CoV-2, given the frequency of complications that can lead to high mortality.
- Trial name
- STC-19 (NCT04371471)
- Testing
- STC-19 score
- Where
- France
- Volunteers
- 91 people
- Sponsor
- Groupe Hospitalier de la Rochelle Ré Aunis
COVID-19
A Study to Investigate the Safety, Immunogenicity of Bivalent mRNA Vaccine RQ3027 and RQ3025 as a Booster Dose in Healthy Adults
This clinical trial aimed to gather safety and immunogenicity data in COVID-19 vaccine-experienced healthy adults. The main questions it aims to answer are: The neutralizing antibodies levels of bivalent mRNA vaccines…
- Trial name
- NCT05907044
- Testing
- RQ3013, RQ3025, RQ3027
- Where
- China
- Volunteers
- 376 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital of Yunnan University
Covid19
Intramuscular and Intravenous VIR-7831 (Sotrovimab) for Mild/Moderate COVID-19.
The COMET-TAIL main study evaluated efficacy, safety, and tolerability of IM sotrovimab versus IV sotrovimab in high-risk patients for the treatment of mild/moderate COVID-19.
- Trial name
- NCT04913675
- Testing
- sotrovimab
- Where
- 50 sites in United States, France and 1 more
- Volunteers
- 1,065 people
- Sponsor
- Vir Biotechnology, Inc.
Postural Orthostatic Tachycardia Syndrome
Efficacy and Safety Study of Efgartigimod in Adults With Post-COVID-19 POTS
The study aims to investigate the safety, tolerability, efficacy, pharmacodynamics (PD), pharmacokinetics (PK), and immunogenicity of efgartigimod compared to placebo in participants with post-COVID-19 postural orthostatic…
- Trial name
- POTS (NCT05633407)
- Testing
- Efgartigimod
- Where
- 11 sites in United States
- Volunteers
- 53 people
- Sponsor
- argenx
Pneumonia, Covid19
Prone Position to Improve Oxygenation in COVID-19 Patients Outside Critical Care
Prone positioning is known to improve the PaO2/FiO2 ratio and reduce mortality in patients with ARDS managed in the critical care setting.
- Trial name
- PRONE-COVID (NCT04589936)
- Testing
- Prone positioning
- Where
- United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Long COVID Syndrome
Does Taurine Supplementation Improve Vascular Function and Orthostatic Responses in Long COVID?
Millions have developed Long COVID (LC), and recent findings show an association between taurine deficiency (an amino acid) and symptoms in LC.
- Trial name
- NCT07312409
- Testing
- Taurine supplementation
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- York University
Lung Fibrosis Interstitial, Post-COVID-19 Syndrome
Effect of Aerobic Exercises Versus Incentive Spirometer Device on Post-covid Pulmonary Fibrosis Patients
the aim of this study will be to investigate the effect of aerobic exercises vs incentive spirometer device on post-covid patients with residual lung diseases.
- Trial name
- NCT06191367
- Testing
- Aerobic Exercises, Incentive Spirometer Device, Traditional Chest Physiotherapy
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- McCarious Nahad Aziz Abdelshaheed Stephens
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