Clinical trials: Covid19- Coronavirus- Sars-cov-2
Covid19, SARS CoV 2 Infection
COVID-19: A Scope Research on Epidemiology and Clinical Course
Severe Acute Respiratory Syndrome (SARS) Coronavirus (CoV) 2 infection and the associated coronavirus disease 2019 (COVID-19) are the most recent international health threat challenging our ability to protect populations, to…
- Conditions
- Covid19, SARS CoV 2 Infection, Sequelae of; Infection
- Trial name
- COVID-Scope (NCT05046769)
- Where
- Portugal
- Volunteers
- 5,000 people
- Sponsor
- Instituto de Saude Publica da Universidade do Porto
COVID-19
Effect of Vitamin D on Morbidity and Mortality of the COVID-19
Patients diagnosed of COVID-19 disease are randomized to receive a single dose of 100.000 IU of Cholecalciferol (Vitamin D arm) or no vitamin D (on top of the current medication used to treat COVID 19).
- Trial name
- COVID-VIT-D (NCT04552951)
- Testing
- Cholecalciferol
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Fundación para la Investigación Biosanitaria del Principado de Asturias
Covid19
Low Dose Lung Radiotherapy to Treat COVID-19 Pneumonia
The purpose of this study is to document the feasibility and tolerability of low dose thoracic radiotherapy in patients with WHO level 5 COVID 19 infections.
- Trial name
- NCT04572412
- Testing
- Low dose Radiotherapy
- Where
- United Kingdom
- Volunteers
- 2 people
- Sponsor
- Lancashire Teaching Hospitals NHS Foundation Trust
Covid19, Hypertension
Inspiratory Muscle Trainer and Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) COVID-19 Persistent Symptoms
Inspiratory muscle training considered as safe and valid method to improve respiratory muscle strength and functional capacity among uncountable conditions which could improve post COVID-19 persistent symptoms including but not…
- Conditions
- Covid19, Hypertension, Corona Persistent Symptoms
- Trial name
- NCT04919031
- Testing
- Inspiratory muscle trainer, diaphragmatic release
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
SARS CoV 2 Infection
A Safety and Tolerability Study of Sotrovimab (VIR-7831) Prophylaxis Against COVID-19 in Immunocompromised Individuals
This is an open-label study examining the safety and tolerability of sotrovimab, administered in two sequential doses as prophylaxis in immunocompromised patients with impaired humoral immunity against SARS-CoV-2.
- Trial name
- NCT05210101
- Testing
- Sotrovimab
- Where
- 3 sites in United States
- Volunteers
- 93 people
- Sponsor
- Sophia Koo, M.D.
COVID-19 Respiratory Infection, SARS-CoV-2 Infection
Benefit of Expanded Surveillance of Nursing Homes During the COVID-19 Pandemic
Residents in nursing homes for the senior citizens (NH) are at high risk for death from COVID-19. We investigated whether repeated non-mandatory RT-PCR SARS-CoV-2 surveillance of NH staff and visitors reduces COVID-19 incidence…
- Trial name
- NCT04933981
- Testing
- Nasopharyngeal swab for SARS-CoV-2
- Where
- Germany
- Volunteers
- 1,587 people, healthy volunteers welcome
- Sponsor
- University of Cologne
Contamination by COVID 19 During Oral Care
Risk of Contamination by COVID-19 During Oral Care With Aerosolization
The sudden Covid-19 pandemic has led all healthcare workers to adapt to an unprecedented situation by continuing to provide care while protecting themselves and their patients.
- Trial name
- Bu-Covid (NCT04817319)
- Testing
- Oral care with/without aerosolization
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
COVID-19
Investigation of the B- and T-cell Repertoire and Immune Response in Patients With Acute and Resolved COVID-19 Infection
Background: People who get infected with COVID-19 have an unpredictable risk to worsen and die. This makes it hard to decide who can quarantine at home and who should be treated at a hospital.
- Trial name
- NCT04362865
- Where
- 4 sites in United States
- Volunteers
- 679 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Xerostomia, COVID-19
The Use of Photobiomodulation in the Treatment of Oral Complaints of Long COVID-19.A Randomized Controlled Trial.
Coronavirus (COVID-19) is a newly emerging zoonotic agent that emerged in December 2019 in China (2019-nCoV) as a Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV -2).
- Conditions
- Xerostomia, COVID-19, Long COVID, Persistent COVID-19
- Trial name
- NCT05760092
- Testing
- Institutional standard treatment for xerostomia and Long Covid, Photobiomodulation Therapy
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- University of Nove de Julho
COVID-19, SARS-CoV2 Infection
Topical Antibacterial Agents for Prevention of COVID-19
The primary objective of this study is to determine whether intranasal application of aminoglycoside (Neosporin) increases local nasal innate immune responses compared to placebo control in healthy participants.
- Trial name
- NCT05449392
- Testing
- Neosporin, Vaseline
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Yale University
COVID-19, Hypoxic Respiratory Failure
Almitrine and COVID-19 Related Hypoxemia
In severe COVID-19 pulmonary failure, the profound hypoxemia is mainly related to pulmonary vasodilation with altered hypoxic pulmonary vasoconstriction (HPV).
- Trial name
- NCT04380727
- Where
- France
- Volunteers
- 17 people
- Sponsor
- Central Hospital, Nancy, France
Endophthalmitis and Orbital Cellulitis
Combined Endophthalmitis and Orbital Cellulitis in Patients With Novel Coronavirus Disease (COVID-19)
To report on cases presented with combined endophthalmitis and orbital cellulitis as a first presentation of covid-19 infection.
- Trial name
- NCT04456556
- Where
- Egypt
- Volunteers
- 5 people
- Sponsor
- Minia University
COVID-19
Study to Monitor the Occurrence of Viral Variants in Patients With Compromised Immune Systems Being Treated for COVID-19
Sotrovimab binds to a conserved epitope on the severe acute respiratory syndrome coronavirus (SARS-CoV) and SARS-CoV-2 spike protein outside the receptor-binding motif and has been shown to reduce the risk of hospitalization…
- Trial name
- LUNAR (NCT05305651)
- Testing
- Sotrovimab
- Where
- 8 sites in United Kingdom
- Volunteers
- 217 people
- Sponsor
- GlaxoSmithKline
COVID - 19, Influenza A
Evaluation of COVID-19 and Flu A/B 3 in 1 Combo Rapid Test
This observational study aims to evaluate the diagnostic performance of an investigational Influenza A/B and COVID-19 test in patients presenting with signs and symptoms of respiratory infection.
- Conditions
- COVID - 19, Influenza A, Influenza B
- Trial name
- NCT07190131
- Testing
- Investigational Flu A/B And Covid-19 Diagnostic Test
- Where
- 15 sites in United States, Puerto Rico
- Volunteers
- 588 people
- Sponsor
- iHealth Labs inc
Covid19
Estetrol (E4) for the Treatment of Patients With Confirmed SARS-COV-2 Infection
It has been reported in several research studies that men are almost twice as likely to progress to severe COVID 19 disease and die than women.
- Trial name
- NCT04801836
- Testing
- Estetrol monohydrate 15 mg
- Where
- 25 sites in Belgium, Hungary and 2 more
- Volunteers
- 162 people
- Sponsor
- NEURALIS s.a.
COVID-19
Phase Ⅱ and Ⅲ Trial of a SARS-CoV-2 Vaccine LYB001
The phase Ⅱ trial adopts a randomized, double-blind, placebo-controlled design to evaluate the immunogenicity and safety profile of LYB001 in healthy adults aged 18 years and older.
- Trial name
- NCT05137444
- Testing
- LYB001
- Volunteers
- 1,900 people, healthy volunteers welcome
- Sponsor
- Yantai Patronus Biotech Co., Ltd.
COVID-19, COVID-19 Pandemic
Accelerating COVID-19 Clinical Recovery in the Outpatient Setting: Retrospective Analysis
The purpose of this retrospective study is to evaluate the effectiveness of CPM nasal spray as part of the treatment of COVID-19 and its impact on clinical symptoms. Two cohort groups will be compared (CPM vs. standard care).
- Conditions
- COVID-19, COVID-19 Pandemic, COVID-19 Respiratory Infection, SARS CoV 2 Infection
- Trial name
- ACCROS-R (NCT05520944)
- Testing
- ClorNovir® (Chlorpheniramine) 0.4% Nasal Spray
- Where
- Dominican Republic
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Dr. Ferrer BioPharma
COVID-19 Pandemic, COVID-19 Vaccines
UNAIR Inactivated COVID-19 Vaccine INAVAC as Heterologue Booster (Immunobridging Study) in Adolescent Subjects
This is an open label trial. There will only be 1 group in the study. All subjects will receive INAVAC vaccine and be followed for 6 months. The vaccine will be administered intramuscularly.
- Trial name
- NCT06272253
- Testing
- INAVAC (Vaksin Merah Putih - UA- SARS CoV-2 (Vero Cell Inactivated) 5 μg
- Where
- Indonesia
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Dr. Soetomo General Hospital
Respiratory Viral Infections, Influenza
Effect of MxA Guidance on Antiviral Treatment in Respiratory Viral Infections
The goal of this clinical trial is to evaluate the effects of myxovirus resistance protein A (MxA)-guided antiviral treatment on treatment duration and adverse outcomes in adults hospitalized with influenza or COVID-19, compared…
- Conditions
- Respiratory Viral Infections, Influenza, SARS CoV 2 Infection
- Trial name
- NCT07892872
- Testing
- Baseline MxA testing, Serial MxA testing, MxA result feedback and antiviral treatment recommendations
- Where
- China
- Volunteers
- 618 people
- Sponsor
- Capital Medical University
Mild to Moderate COVID-19
Evaluate the Efficacy and Safety of FB2001 for Inhalation in Patients With Mild to Moderate COVID-19
This study is a double-blind,randomized,placebo-controlled study to evaluate the efficacy and safety of FB2001 for Inhalation in patients with mild to moderate Coronavirus Disease 2019(COVID-19).
- Trial name
- NCT05675072
- Testing
- FB2001
- Where
- China
- Volunteers
- 1,336 people
- Sponsor
- Frontier Biotechnologies Inc.
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