Clinical trials: Covid19- Coronavirus- Sars-cov-2
Covid19, SARS-CoV Infection
Epidemiologic Assessment of SARS-CoV-2 (COVID-19) Prevalence in Minnesota
The purpose of this epidemiologic study is to estimate the prevalence and incidence of anti-SARS-CoV-2 antibodies in at-risk, exposed, affected populations.
- Conditions
- Covid19, SARS-CoV Infection, SARS-CoV-2, Corona Virus Infection
- Trial name
- NCT04473183
- Testing
- Specimen Collection, Surveys
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Minnesota
Health, Subjective, Healthy
Determining the Physical Activity Level of Healthy Adults During Pandemic
Abstract Background: With Covid-19 pandemic, online education, remote and flexible working were introduced. Thus the process of stay-at-home began.
- Trial name
- NCT04555954
- Testing
- surveys and questionnaires
- Where
- Turkey (Türkiye)
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
COVID-19 Pandemic
The Offer of Neurosurgery Care in the Grand Est of France During the Health Crisis Linked to Covid-19
During this exceptional health crisis, this study of the current care of a neurosurgical activity, which is essential in a University Hospital Centre, will enable us to better understand how we function, the response given to a…
- Trial name
- NeurochirCOVID (NCT04701905)
- Where
- France
- Volunteers
- 450 people
- Sponsor
- University Hospital, Strasbourg, France
Depression, COVID-19
Effectiveness and Tolerability of аgomelatine in the Treatment of Patients With Depression After SARS-CoV-2 (TELESPHOR)
This is a multi-centre, observational, non-interventional study, which will prospectively collect clinical and socio-demographic data from patients with depression occurred after COVID 19 in real clinical settings during 8 weeks…
- Trial name
- TELESPHOR (NCT05323994)
- Where
- Russia
- Volunteers
- 104 people
- Sponsor
- Servier Russia
Covid-19 Positivity Confirmed With PCR Positivity in the Nasopharyngeal Swab, Symptomatic Covid -19 Positive Patients Who Require Hospitalization
PAI-1 Levels and Predicting Covid-19 Patients' Prognosis
The primary aim of our study is to understand the effects of Covid-19 disease on vascular inflammation and coagulation cascade, and secondarily, to investigate its utility in predicting disease prognosis by analyzing serum PAI-1…
- Conditions
- Covid-19 Positivity Confirmed With PCR Positivity in the Nasopharyngeal Swab, Symptomatic Covid -19 Positive Patients Who Require Hospitalization, Patients Who Did Not Vaccinate Against Covid-19, Patients Among 20 to 90 Years of Age
- Trial name
- NCT04997928
- Testing
- Serum PAI-1 alpha analysis.
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Cystic Fibrosis, Covid19
COVID-19 Antibody Responses in Cystic Fibrosis
Coronavirus disease 2019 (COVID-19) which is caused by the virus SARS-CoV-2 has resulted in an ongoing global pandemic. It is unclear whether the relatively low number of reported cases of COVID-19 in people with CF (pwCF) is due…
- Trial name
- CAR-CF (NCT04992234)
- Where
- 2 sites in Sweden
- Volunteers
- 113 people
- Sponsor
- Vastra Gotaland Region
COVID - 19, Renal Transplant
Safety and Effectiveness of a Remdesivir Treatment to Prevent Severe COVID-19 in Kidney Transplant Patients
Since the start of the COVID-19 pandemic, the approach to solid organ transplantation has evolved. Transplants using organs (excluding lungs) from COVID-19-positive donors have shown short-term safety, but there is limited data…
- Conditions
- COVID - 19, Renal Transplant, SARS CoV 2 Infection
- Trial name
- COVIDKIDNEY (NCT07197164)
- Testing
- Remdesivir (RDV)
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia
Covid19, SARS-CoV Infection
COVID-FIS: Pilot in COVID-19 (SARS-CoV-2) of Fisetin in Older Adults in Nursing Homes
The purpose of this study is to test whether Fisetin, a senolytic drug, can assist in preventing an increase in the disease's progression and alleviate complications of coronavirus due to an excessive inflammatory reaction.
- Trial name
- COVID-FIS (NCT04537299)
- Testing
- Fisetin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Post-COVID-19 Syndrome, Fatigue Post Viral
Yoga Versus Health Education for the Treatment of Persistent Fatigue in Patients With Post COVID-19 Syndrome
Evaluation of the short- and medium-term effect of a yoga intervention in addition to routine care compared to health education in addition to routine care on fatigue in patients with post covid syndrome.
- Trial name
- YoFaPoCo (NCT05890599)
- Testing
- Yoga Therapy, Health Education
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University Hospital Tuebingen
Covid19
Study of the EpiVacCorona Vaccine With the Involvement of Volunteers Aged 60 Years and Above
The aim of the clinical study is to study the safety, reactogenicity and immunogenicity indicators of the EpiVacCorona vaccine, with the involvement of volunteers aged 60 years and above.
- Trial name
- NCT05021016
- Testing
- EpiVacCorona (EpiVacCorona vaccine based on peptide antigens for the prevention of COVID-19)
- Where
- Russia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Federal Budgetary Research Institution State Research Center of Virology and Biotechnology "Vector"
Covid19, SARS-CoV Infection
COVID-19 IgG Formation in Physicians at ALGH and Their Household Members
This study is a community hospital-based study that will enhance information being obtained in similar studies taking place in France, Denmark, and China.
- Conditions
- Covid19, SARS-CoV Infection, Communicable Disease
- Trial name
- NCT04540484
- Testing
- Screening
- Where
- United States
- Volunteers
- 507 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
COVID-19
Pathogenesis of BTK-mediated Hyper-Inflammatory Responses in COVID-19 (RESPOND)
Background: Coronavirus disease 2019 (COVID-19) is an acute respiratory syndrome. It is caused by the SARS-CoV-2 virus. People with severe COVID-19 infection have a hyper-inflammatory response.
- Trial name
- NCT04394884
- Where
- 3 sites in United States
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Hypotension, Regional Anesthesia Morbidity
Spinal Anesthesia Related Hypotension in SARS-CoV-2 (COVID-19) Pregnant Patients
Since the onset of COVID-19, recommendations suggest the use of neuraxial anesthesia, if possible, over general anesthesia for cesarian section to avoid the risks of aerosolization associated with tracheal intubation and…
- Conditions
- Hypotension, Regional Anesthesia Morbidity, SARS-CoV2 Infection
- Trial name
- NCT05085652
- Testing
- spinal anesthesia induced hypotension in SARS-CoV-2 patients.
- Where
- Turkey (Türkiye)
- Volunteers
- 251 people
- Sponsor
- Ankara City Hospital Bilkent
COVID-19
Study to Evaluate the Safety and Immunogenicity of SARS-CoV-2 Vaccine (IN-B009) in Healthy Adults (COVID-19)
This is a first in human, phase I, open-label, dose-escalation study to assess the safety, reactogenicity, and immunogenicity of a SARS-CoV-2 Vaccine (IN-B009) in healthy adults.
- Trial name
- NCT05113849
- Testing
- IN-B009 (Low-dose), IN-B009 (High-dose)
- Where
- 3 sites in South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- HK inno.N Corporation
SARS-CoV-2
GLS-5310 Vaccine for the Prevention of SARS-CoV-2 (COVID-19)
This clinical trial will evaluate the safety, tolerability and immunogenicity of GLS-5310 DNA vaccine against SARS-CoV-2(COVID-19) in healthy volunteers.
- Trial name
- NCT04673149
- Testing
- GLS-5310
- Where
- South Korea
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- GeneOne Life Science, Inc.
COVID-19
A Study of a Potential Oral Treatment to Prevent COVID-19 in Adults Who Are Exposed to Household Member(s) With a Confirmed Symptomatic COVID-19 Infection
The purpose of this clinical trial is to learn whether the study medicine prevent symptoms of COVID-19 in adults who have been exposed to household member(s) with a confirmed symptomatic COVID-19 infection.
- Trial name
- NCT05047601
- Testing
- PF-07321332, Ritonavir
- Where
- 170 sites in United States, Argentina and 15 more
- Volunteers
- 2,954 people
- Sponsor
- Pfizer
COVID-19
Evaluation of Safety & Efficacy of MIR 19 ® Inhalation Solution in Patients With Mild COVID-19
The aim of this study is to evaluate the effectiveness and safety of MIR 19 ® in preventing development of moderate and/or severe course of the disease in mild COVID-19 outpatients.
- Trial name
- NCT05783206
- Testing
- MIR 19 ®, Standard therapy
- Where
- Russia
- Volunteers
- 984 people
- Sponsor
- National Research Center - Institute of Immunology Federal Medical-Biological Agency of Russia
COVID-19
Impact of Long COVID-19 on the Health and Quality of Life of Military Personnel (Active or Retired) and Their Families
Severe and sometimes irreversible sequelae are observed in people who have developed a severe form of COVID-19 (pulmonary, cardiovascular, renal, neurological sequelae among others).
- Trial name
- IMP@LA (NCT05200832)
- Testing
- Online questionnaire, Semi-structured interview
- Where
- France
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
COVID-19 Infection
Novel Coronavirus Infection and Reproductive Function
This study aims to observe the impact of COVID-19 infection on the reproductive function and assisted pregnancy outcome of infertile couples undergoing assisted reproductive technology and to determine which factors are related…
- Trial name
- NCT05685992
- Testing
- no intervention
- Where
- 3 sites in China
- Volunteers
- 400 people
- Sponsor
- Jinling Hospital, China
COVID-19, Acute Respiratory Distress Syndrome
Efficacy and Safety of aerosolizedDornase Alfa Administration in Patients With COVID19 Induced ARDS (COVIDORNASE)
This study plans to learn more about the effects of Dornase Alfa in COVID19 (coronavirus disease of 2019) patients, the medical condition caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
- Trial name
- COVIDORNASE (NCT04355364)
- Testing
- Dornase Alfa Inhalation Solution [Pulmozyme], standard procedure
- Where
- France
- Volunteers
- 77 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
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