Clinical trials: Covid19- Coronavirus- Sars-cov-2
COVID
Collection of Coronavirus COVID-19 Outbreak Samples in New South Wales
The objectives of this study are to characterise immune responses in people with CoV-SARS-2 infection and use this knowledge to advance vaccine design, treatment options, and diagnostic reagents.
- Trial name
- COSiN (NCT04383652)
- Testing
- Biological sample and clinical data collection
- Where
- 9 sites in Australia
- Volunteers
- 200 people
- Sponsor
- Kirby Institute
SARS-CoV-2 Infection
Asymptomatic COVID-19 Trial
The coronavirus disease-2019 (COVID-19) is spreading throughout the United States. While there are no known therapies to treat those who have become sick, there have been some reports that a medication currently used to treat…
- Trial name
- ACT (NCT04374552)
- Testing
- Hydroxychloroquine sulfate &Azithromycin
- Where
- United States
- Sponsor
- Rutgers, The State University of New Jersey
Coronavirus Disease 2019 (COVID-19)
Observational Study of Convalescent Plasma for Treatment of Veterans With COVID-19
The purpose of this study is to assess whether convalescent plasma therapy is associated with reduced 30-day all-cause mortality in a population of Veteran inpatients with non-severe coronavirus disease 2019 (COVID-19).
- Trial name
- NCT04545047
- Testing
- COVID-19 convalescent plasma
- Where
- 2 sites in United States
- Volunteers
- 5,044 people
- Sponsor
- VA Office of Research and Development
Determine Effect of Urological Malpractice During Covid 19 on Patient Complications
The Impact of Covid 19 Pandemic on Ureteric Stents Complications.
The pandemic of coronavirus disease 2019 (COVID-19) has serious implications on urology practice and raises particular questions for urologists about the management of different conditions.
- Trial name
- NCT05839249
- Testing
- JJ urological stents
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- South Valley University
COVID-19
Use of Multiple Doses of Convalescent Plasma in Mechanically Intubated Patients With COVID-19
This study will assess the feasibility and safety of administering multiple doses of convalescent plasma to Covid-19 positive patients admitted to the Intensive Care Unit (ICU) receiving mechanical ventilation.
- Trial name
- NCT05595538
- Testing
- Multiple doses of anti-SARS-CoV-2 Convalescent Plasma
- Where
- Panama
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hospital Regional Dr. Rafael Estévez
COVID-19
Immune Responses to COVID-19 Infection or Vaccination
The overall purpose of this observational cohort study is to characterize COVID-specific immune responses to SARS-CoV-2 exposure or COVID vaccination in a real-world setting.
- Trial name
- NCT05379478
- Testing
- Laboratory assessment of antibody profiles
- Where
- United States
- Volunteers
- 403 people
- Sponsor
- Aditxt, Inc.
Coronavirus Infections, Pneumonia, Viral
Safety and Efficacy of Hydroxychloroquine Associated With Azithromycin in SARS-CoV2 Virus (Coalition Covid-19 Brasil II)
The Severe Acute Respiratory Syndrome COronaVirus 2 (SARS-CoV2) is a new and recognized infectious disease of the respiratory tract.
- Trial name
- NCT04321278
- Testing
- Hydroxychloroquine + azithromycin, Hydroxychloroquine
- Where
- 58 sites in Brazil
- Volunteers
- 440 people
- Sponsor
- Hospital Israelita Albert Einstein
Coronavirus Disease 2019
Clinical Study on the Immune Program of Recombinant Novel Coronavirus（COVID-19) Vaccine (CHO Cell)
Popular topic：Clinical study on the immune program of recombinant Novel Coronavirus (COVID-19) vaccine (CHO cell). Research purpose:Main purpose: To evaluate the immunogenicity of recombinant novel coronavirus vaccine (CHO cells)…
- Trial name
- NCT05128643
- Testing
- Recombinant novel coronavirus vaccine (CHO cell)
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
Covid19
The Role of CT Chest Scan in the Pre-anesthetic Assessment of Suspected or Confirmed COVID -19 Patients
The role of CT scan of the chest in Pre-anesthetic assessment of the severity of COVID-19 and the correlations between CT measurements of the aortic and pulmonary arteries diameters and severity of pneumonia.
- Trial name
- NCT04560530
- Testing
- Non-enhanced CT scan of the chest
- Where
- Saudi Arabia
- Volunteers
- 76 people
- Sponsor
- Tanta University
SARS-CoV-2, SARS-CoV-2 (COVID-19) Infection
Study SARS-CoV-2-CZ-PREVAL-II - Arm of the Olomouc Region
The aim of the study is to find the proportion of people in the population of the Olomouc Region with the presence of IgG (or IgM) antibodies against the S and N antigens of the SARS-CoV-2 virus, therefore people who have already…
- Trial name
- NCT07387211
- Testing
- Blood sampling, Gargle sampling, Questionnaire completion
- Where
- Czechia
- Volunteers
- 2,484 people, healthy volunteers welcome
- Sponsor
- The Institute of Molecular and Translational Medicine, Czech Republic
Long COVID, Long COVID-19 Syndrome
Quality of Life After Hyperbaric Oxygen Therapy in Post-COVID Patients
Post-Covid syndrome, also known as long Covid, is a clinical condition in which patients experience long term symptoms after Covid-19 infection. Treatment options for post-Covid are not effective.
- Conditions
- Long COVID, Long COVID-19 Syndrome, Long Covid19, Long Covid 19
- Trial name
- QoL COVID HBOT (NCT06159309)
- Testing
- Hyperbaric oxygen therapy
- Where
- 6 sites in Netherlands
- Volunteers
- 200 people
- Sponsor
- Rutger Lalieu
COVID-19, Convalescent Plasma Treatment
Convalescent Plasma Transfusion in Severe COVID-19 Patients in Jamaica
Corona virus Disease 2019 (COVID-19) can be a severe respiratory illness caused by Severe Acute Respiratory Syndrome (SARS-CoV2) for which there is no standard treatment in affected persons nor a vaccine to prevent the infection.
- Trial name
- NCT04644198
- Testing
- Convalescent Plasma Infusion
- Where
- Jamaica
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of The West Indies
Covid19
SERUR: COVID-19 Serological Survey of Staff From the University Reims-Champagne Ardennes
This study was designed to determine, in a screening situation within the framework of university preventive medicine, the prevalence of positive anti-SARS-Cov 2 serology among the staff of the University of Reims…
- Trial name
- SERUR (NCT04816084)
- Testing
- Anti-SARS-CoV2 Serology
- Where
- France
- Volunteers
- 389 people, healthy volunteers welcome
- Sponsor
- Université de Reims Champagne-Ardenne
Corona Virus Infection, Coronavirus
imPulse™ Una Full-spectrum, Over Clothing E-stethoscope
This study generates robust clinical data to train ML/AI algorithms of the Sponsor's imPulse™ Una full-spectrum e-stethoscope for digital diagnostic feature synthesis of symptomatic SARS-CoV-2/COVID-19 biosignatures for rapid and…
- Trial name
- NCT04556149
- Testing
- imPulse™ Una e-stethoscope, Philips Lumify Ultrasound System
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Level 42 AI, Inc.
COVID-19
SA55 Novel Coronavirus Broad-spectrum Neutralizing Antibody Nasal Spray in Health People
To evaluate the safety, tolerance, local drug content and neutralization activity in nasal cavity, systemic exposure level and immunogenicity of novel coronavirus broad-spectrum neutralizing antibody SA55 nasal spray.
- Trial name
- NCT06048393
- Testing
- SA55 nasal spray
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sinovac Life Sciences Co., Ltd.
Congenital Heart Disease, Covid-19
Impact of Covid-19 in Congenital Heart Disease
The ongoing Coronavirus (Covid-19) pandemic has recently generated the first epidemiological data on populations at risk. Currently, the risk factors, recognized for severe forms of Covid-19 infection, are elderly patients (> 70…
- Trial name
- COVID-CHD (NCT04336384)
- Where
- France
- Volunteers
- 5,000 people
- Sponsor
- University Hospital, Montpellier
SARS-CoV-2 (COVID-19)
Development of a Controlled Human Infection Model for Assessment of SARS-CoV-2 Omicron Subvariants
COVHIC003 is a human infection challenge study in which healthy adults aged 18-50 previously vaccinated with an approved COVID-19 vaccine will be administered a SARS-CoV-2 Omicron EG.5.1 variant given by drops in the nose.
- Trial name
- COVHIC003 (NCT07397455)
- Testing
- SARS-CoV-2 Omicron EG.5.1 challenge agent 10^5 TCID50, SARS-CoV-2 Omicron EG.5.1 challenge agent 10^6 TCID50, SARS-CoV-2 Omicron EG.5.1 challenge agent 10^4 TCID50
- Where
- 5 sites in United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Coronavirus Disease 2019
COVID-19 Associated Lymphopenia Pathogenesis Study in Blood
Background: COVID-19 is an acute respiratory syndrome. One symptom of COVID-19 is a reduction in the number of cells called lymphocytes in the blood. Lymphocytes are a type of white blood cell that fights infections.
- Trial name
- NCT04401436
- Where
- 3 sites in United States
- Volunteers
- 240 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Covid19
Minimizing the Effects of COVID-19 Hospitalization With the COVID Rehabilitation Program for the Elderly
Although evidence from the management of other viral respiratory infections suggest that early multidisciplinary rehabilitation could mitigate the adverse effects of the severe form of the illness, and reduce the length of…
- Trial name
- CORE (NCT04771052)
- Testing
- COVID Rehabilitation Program for the Elderly (CORE)
- Where
- 2 sites in Canada
- Volunteers
- 124 people
- Sponsor
- Université de Sherbrooke
SARS-CoV2 Infection
Rural Tailored COVID-19 Communication to Promote SARS-CoV-2 Antibody Testing in Saliva
This study seeks to evaluate communication strategies for better encouraging understanding and uptake of salivary SARS-CoV-2 antibody testing among individuals residing in rural Northern Michigan.
- Trial name
- NCT06085547
- Testing
- General SARS-CoV-2 Communication, Rural-Targeted SARS-CoV-2 Communication
- Where
- United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Michigan State University
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