Clinical trials: Craniopharyngioma, Child, open to volunteers
Craniopharyngioma, Child
SEMAFORCRANIO : Multicenter, Double-blind, Parallel, Randomized Controlled Trial of the Efficacy of Semaglutide in Hypothalamic Obesity Secondary to Craniopharyngioma in Children Aged 12 to 17 Years
Craniopharyngioma (CP) is a rare embryonic brain tumor of the sellar and parasellar region. Despite its benign histologic characteristics, it is locally aggressive and may cause severe morbidity from invasion into adjacent…
- Trial name
- SEMAFORCRANIO (NCT07845994)
- Testing
- Semaglutide (Wegovy) weekly injection
- Where
- 17 sites in France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Angers
Craniopharyngioma, Child, Craniopharyngioma
Tovorafenib for Treatment of Craniopharyngioma in Children and Young Adults
The current study assesses the tolerability and efficacy of monotherapy with pan-RAF-kinase (Tovorafenib) inhibition for the treatment of children and young adults with craniopharyngioma.
- Conditions
- Craniopharyngioma, Child, Craniopharyngioma, Recurrent Craniopharyngioma
- Trial name
- PNOC029 (NCT05465174)
- Testing
- Tovorafenib
- Where
- 20 sites in United States, Australia
- Volunteers
- 57 people
- Sponsor
- Sabine Mueller, MD, PhD
Craniopharyngioma, Child
Prospective Pilot Study Identifying Clinically Relevant Biological Targets for Medical Therapy
New data suggests that the current treatment for pediatric adamantinomatous craniopharyngioma (CPA) may not be as effective as it could be.
- Trial name
- NCT03610906
- Testing
- Tumor and Blood Specimens
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Colorado, Denver