Clinical trials: Craving
Stress, Pain
State-dependent Interoception, Value-based Decision-making, and Introspection
Background: Negative emotional states can affect a person s behavior as they make decisions. For example, hunger may make people more impatient; they may then make riskier choices.
- Conditions
- Stress, Pain, Emotions, Craving
- Trial name
- NCT05666726
- Testing
- Pain, Stress, Craving
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Alcohol Use Disorder, Inflammatory Response
Endotoxin Exposure to Examine the Role of Inflammation in Alcohol Use
The study design consists of a randomized, double-blind, placebo-controlled study of low dose endotoxin. Individuals with current AUD (n=32) and matched controls without AUD (n=32) will be randomly assigned to receive a single…
- Conditions
- Alcohol Use Disorder, Inflammatory Response, Craving
- Trial name
- NCT07452146
- Testing
- Endotoxin
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Appetite, Binge Eating Behaviour
Effects of Home-Based Transcranial Direct Current Stimulation on Appetite
This randomized, placebo-controlled, double-blind, parallel-design study aims to evaluate the neurophysiological effects of home-based transcranial direct current stimulation (tDCS) on appetite in adults with binge eating…
- Conditions
- Appetite, Binge Eating Behaviour, Food Cravings
- Trial name
- NCT07757438
- Testing
- Active Home-Based tDCS
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Cognitive Function, Fatigue
A Clinical Trial to Evaluate the Effects of a Supplement on Cognitive Function and Energy Levels
This study evaluates the effects of Artah's Cellular Hydration electrolyte supplement on cognitive function and energy levels in healthy adults aged 25-60 who experience mild to moderate fatigue, brain fog, or related symptoms.
- Conditions
- Cognitive Function, Fatigue, Energy Levels, Mental Clarity
- Trial name
- NCT07755475
- Testing
- Cellular Hydration Supplement
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Artah Nutrition Limited
Opioid Craving, Opioid Use Disorder
Developing a Clinical Outcome Assessment for Opioid Craving
The purpose of this study is to collect information about opioid craving so that the investigators can develop an opioid craving assessment to improve treatments for individuals with opioid use disorder.
- Conditions
- Opioid Craving, Opioid Use Disorder, Measure Development
- Trial name
- NCT05109429
- Testing
- Neutral Cue-induced Craving, Visual Opioid Cue-induced Craving, Visual and Tactile Opioid Cue-induced Craving
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Emotional Eating, Overweight or Obesity
Efficacy of Satisens® in Reducing Emotional Eating
This study evaluates the efficacy of Satisens®, a dietary supplement composed of plant extracts, in reducing emotional eating and sweet cravings in healthy adults.
- Conditions
- Emotional Eating, Overweight or Obesity, Hormonal Changes, Neurotransmitter Agents
- Trial name
- Satisens (NCT07079046)
- Testing
- Intervention 1: Satisens®
- Where
- Spain
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- José Enrique de la Rubia Ortí, Ph
Nicotine Dependence, Smoking, Cigarette
Isradipine Enhancement of Virtual Reality Cue Exposure for Smoking Cessation
The proposed study represents a crucial and important stage in translating basic research to strategies for treating nicotine dependence.
- Conditions
- Nicotine Dependence, Smoking, Cigarette, Smoking Cessation, Smoking Behaviors
- Trial name
- NCT03083353
- Testing
- Isradipine, Cue Exposure
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Jasper A. Smits
Nicotine Replacement Therapy, Healthcare Professionals
The Efficacy of Combining Music Intervention With Nicotine Replacement Therapy to Reduce Smoking Craving, Among Healthcare Professionals Who Are Trying to Quit.
Tobacco is the leading preventable cause of death and disease worldwide. The health benefits of quitting smoking are well-documented. Healthcare professionals play a key role in the fight against smoking.
- Conditions
- Nicotine Replacement Therapy, Healthcare Professionals, Tobacco Craving, Tabacco Cessation
- Trial name
- MUSICAT (NCT07412717)
- Testing
- Nicotine Replacement Therapy (NRT, nicotine patch), Music intervention, Biological collection
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Self-Control, Food Cravings
EXOMIND (BTL-699-2) for the Improvement in Willpower & Food Cravings
The goal of this clinical trial is to evaluate if the treatment with ExoMIND (BTL-699-2) device is able to improve willpower, self-control and food cravings in adults above the age of 22 years.
- Trial name
- NCT07056036
- Testing
- ActiveTreatment with BTL-699-2
- Where
- 4 sites in United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Food Cravings
EXOMIND (BTL-699) for the Reduction of Food Cravings
The goal of this clinical trial is to evaluate if the treatment with BTL-699 device is able to temporarily reduce food cravings in adults above the age of 22 years.
- Trial name
- NCT06889298
- Testing
- Treatment with BTL-699
- Where
- Czechia
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Alcohol Use Disorder, Inflammatory Response
An Inflammatory Challenge Using Endotoxin
The study design consists of a randomized, double-blind, placebo-controlled trial of low dose endotoxin. The low dose endotoxin challenge induces a transient systemic inflammatory response with normalization of cytokine levels…
- Conditions
- Alcohol Use Disorder, Inflammatory Response, Craving, Depressed Mood
- Trial name
- NCT04310423
- Testing
- Endotoxin
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Healthy, Nutrition, Healthy
Postprandial Metabolic and Appetite Responses to Different Food Intake Sequences in Athletes
Emerging evidence suggests that following a 'carbohydrate-last meal pattern', wherein foods rich in protein, fat, fiber, and/or polyphenols are consumed before sources of simple carbohydrate (CHO) in a meal, results in reduced…
- Conditions
- Healthy, Nutrition, Healthy, Postprandial Hyperglycemia, Hunger
- Trial name
- NCT06365385
- Testing
- Carbohydrate-last meal pattern, Carbohydrate-first meal pattern
- Where
- Portugal
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Craving
Gut Health and the Effect on Substance and Alcohol Cravings
Gut health has been linked with improvement in mental health but no research has been done to evaluate if improving gut health can have an effect on alcohol and substance cravings.
- Trial name
- NCT06026982
- Testing
- probiotic and pickle
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- City Rescue Mission Medical Clinic
Opioid Withdrawal, Opioid Craving
Oral Cannabidiol for Opioid Withdrawal
This pilot study will examine the safety of the cannabinoid cannabidiol (Epidiolex) in a human laboratory model of clinically relevant withdrawal.
- Conditions
- Opioid Withdrawal, Opioid Craving, Opioid Use Disorder
- Trial name
- NCT04238754
- Testing
- Epidiolex
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Smoking Cessation, HIV
TMS for Smoking Cessation in PLWHA Cessation in People Living With HIV/AIDS (PLWHA)
The pilot study proposal aims to modulate craving and attentional bias towards smoking cues in 40 people living with HIV/AIDS (PLWHA) using transcranial magnetic stimulation (TMS), with functional MRI (fMRI) brain correlates.
- Conditions
- Smoking Cessation, HIV, Craving
- Trial name
- NCT04936594
- Testing
- iTBS, TMS
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Gopalkumar Rakesh
Stress Reaction, Sleep Disturbance
Functional Assessment of Ashwagandaha Root Extract During Weight Loss
Patients who are involved in a clinical protocol driven 12 week medical weight loss intervention will be randomized to receive either a placebo or 600 mg of an ashwagandha root extract.
- Conditions
- Stress Reaction, Sleep Disturbance, Craving, Obesity
- Trial name
- NCT03112824
- Testing
- Ashwagandha Root Extract Capsule
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Craving, Mastication Disorder
Effects of Non-invasive Neuromodulation on Food Desire, Chewing Pattern, Executive Functions and Oxidative Stress.
From the change in self-regulation, memory is inhibited, allowing individuals to suppress or ignore unwanted or outdated associations and thus help to filter information relevant to dietary goals from irrelevant information.
- Conditions
- Craving, Mastication Disorder, Memory Disorders, Executive Dysfunction
- Trial name
- NCT05046145
- Testing
- speech therapy for chewing + real tDCS
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Piauí
Glucagon-like Peptide-1, Smoking Cessation
Smoking Cessation Facilitated by Glucagon-like Peptide-1 (GLP-1) Analogues
Cigarette smoking is the leading preventable cause of premature death worldwide. However smoking is a very difficult addiction to break whereby main reasons for not quitting or relapsing after cessation are the nicotine…
- Conditions
- Glucagon-like Peptide-1, Smoking Cessation, Weight Change, Body, Craving
- Trial name
- SKIP (NCT03204396)
- Testing
- Dulaglutide, 0.5 ml normal saline (0.9% sodium chloride [0.9% NaCl])
- Where
- Switzerland
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Stress, Sleep
The Impact of Ashwagandha on Perceived Stress, Sleep and Food Cravings in College Students
The purpose of this study was to compare the impact of 700 mg daily ashwagandha (Withania Somnifera) in healthy college students on sleep, stress and food cravings to healthy college students taking placebo.
- Conditions
- Stress, Sleep, Craving, Well Being
- Trial name
- NCT05430685
- Testing
- Ashwagandha
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Colorado Springs
Obesity, Food Craving
The Role of Emotional Arousal in Food Preference and Taste
The purpose of this study is to examine the role of stress in food craving and food consumption in obesity. Using experimentally validated guided imagery procedure, the investigators propose to examine the stress response using…
- Conditions
- Obesity, Food Craving, Food Consumption
- Trial name
- NCT02402088
- Testing
- Stress Imagery, Food Cue Imagery, Neutral-Relaxing
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Yale University