Clinical trials: Creatine
Cryotherapy Effect
Behaviour After Exercise of Biological, Clinical and Metabolic Variables as From Different Temperatures and Times of Immersion Cold Water Application
Introduction: immersion cold water is a recuperative strategy commonly used, however, are not yet fully understood the real effects of this technique on specific conditions.
- Trial name
- NCT02497495
- Testing
- immersion cold water
- Where
- Brazil
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Paulista University
Hypercholesterolemia, Aches
Effectiveness of Creatine in Preventing Muscle Aching From Cholesterol-Lowering Statin Drugs
The purpose of this study is to determine of creatine will prevent or treat the muscle toxicity side effect of statin drug therapy, whose symptoms are aching, cramping, and weakness.
- Conditions
- Hypercholesterolemia, Aches, Cramps, Weakness
- Trial name
- NCT00797407
- Testing
- Creatine
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- The Cleveland Clinic
Huntington's Disease
Premanifest Huntington's Disease Extension Study II: Creatine Safety & Tolerability
The purpose of this clinical trial is to extend the Pre-Crest-X study to further assess the long-term safety and tolerability of up to 30 grams daily creatine in individuals at-risk for Huntington's Disease (HD) and to assess…
- Trial name
- Pre-CREST-2X (NCT01411163)
- Testing
- Creatine monohydrate
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Massachusetts General Hospital
Psychosis
Transcranial Direct Current Stimulation and Cognitive Remediation Therapy for Psychosis
The proposed pilot study is a randomized controlled study to assess effectiveness of transcranial direct current stimulation (tDCS) to enhance cognitive remediation therapy in patients with psychotic disorders. tDCS.
- Trial name
- NCT02085421
- Testing
- tDCS
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Minnesota
Fragile X Syndrome (FXS), Creatine Transporter Deficiency
Optical Imaging in X-linked Disorders.
Fragile X syndrome (FXS, OMIM #300624) and Creatine Transporter Deficiency (CTD, #300352) are the two most common causes of X-linked intellectual disability.
- Trial name
- IMAGINER (NCT06868979)
- Testing
- Clinical assessment, Parental questionnaires, Cognitive assessment
- Where
- France
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Myositis, Juvenile
Exercise, Creatine and Coenzyme Q10 for Childhood Myositis
Children with Juvenile Idiopathic Inflammatory Myopathies (JIIM) are weak and get tired because their muscles aren't able to work like healthy muscles.
- Trial name
- NCT04286178
- Testing
- creatine monohydrate, ubiquinol, glucose tablet
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- The Hospital for Sick Children
Delayed Onset Muscle Soreness, Exercise-Induced Muscle Damage
Mineral-Infused Clothing for Recovery From Muscle Soreness and Muscle Damage After Exercise
The goal of this clinical trial is to learn whether wearing mineral-infused clothing helps muscles recover after a hard bout of unaccustomed exercise in healthy adults aged 18 to 45 who have not done lower-body resistance or jump…
- Trial name
- PERFICT (NCT07873866)
- Testing
- Mineral-infused garment, Non-infused control garment, Muscle-damaging eccentric exercise (drop jumps)
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- StudySetGo
Coronary Artery Disease
Randomized Trial of Creatine-kinase Leak After Rosuvastatin At the Time of Percutaneous Coronary Intervention
Patients with stable coronary disease when undergoing percutaneous coronary intervention may present periprocedural myocardial infarction defined at present as a creatine kinase-myocardial isoenzyme (CK-MB) elevation 3 times…
- Trial name
- CLEAR-PCI (NCT01968577)
- Testing
- Rosuvastatin
- Where
- Brazil
- Volunteers
- 528 people
- Sponsor
- Kleber Bomfim Araujo Martins
Healthy
Creatine Timing and Resistance Training Adaptations.
Emerging evidence suggests that the timing of creatine supplementation may be an important regulator of muscle growth and strength. It is unclear whether creatine ingested before or after resistance training is more beneficial.
- Trial name
- NCT03678857
- Testing
- Creatine
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Brandon University
Prostate Cancer, Sarcopenia
Creatine Supplementation and Resistance Training to Improve Sarcopenia Parameters in Patients With Prostate Cancer After Androgen Deprivation Therapy
This randomized, double-blind, placebo-controlled clinical trial will investigate the effects of creatine supplementation combined with a 12-week supervised resistance training program on muscle mass, muscle strength, physical…
- Trial name
- NCT07463092
- Testing
- Creatine Monohydrate, Maltodextrin, Resistance training
- Where
- Brazil
- Volunteers
- 34 people
- Sponsor
- University of Sao Paulo
Rheumatoid Arthritis
Can Creatine Supplementation Improve Body Composition and Physical Function in Rheumatoid Arthritis Patients?
Rheumatoid arthritis (RA) patients typically experience a significant loss of muscle. In healthy individuals, food supplementation with creatine (Cr) increases muscle size and improves physical function and quality of life.
- Trial name
- NCT01767844
- Testing
- Creatine
- Where
- United Kingdom
- Volunteers
- 43 people
- Sponsor
- Bangor University
Deficiency; Diet
Effect of Creatine Supplementation on Physical Performance in Vegan Subjects
The primary objective of this study is to investigate the effect of creatine monohydrate supplementation on body composition, physical performance, and muscle creatine levels in vegan individuals over four weeks.
- Trial name
- CREATINVEG (NCT06483321)
- Testing
- Creatine Supplementation
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad Francisco de Vitoria
Bipolar Depression
Cytidine- and Creatine-Containing Drug in Treating Bipolar Depression
This proposed research is aimed to investigate the efficacy and safety of combined cytidine- and creatine-containing drug and dietary supplement in treating bipolar depression and to evaluate changes in relevant brain biochemical…
- Trial name
- NCT01543139
- Testing
- Valproate+Cytidine-+Creatine-, Valproate+Cytidine-, Valproate
- Where
- South Korea
- Sponsor
- Ewha Womans University
Improve Muscle Performance in Young Adults
Creatine Supplementation in Young Healthy Adults
The purpose is to compare the effects of bolus ingestion (5 grams) vs. intermittent ingestion (2 x 2.5 grams) of creatine supplementation vs.
- Trial name
- NCT06604793
- Testing
- Creatine
- Where
- Canada
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Regina
Breast Cancer, Supplementation
Creatine Supplementation and Resistance Training in Patients With Breast Cancer
Background: Creatine supplementation is an effective ergogenic nutrient for athletes, as well as people for people starting a health or fitness program.
- Conditions
- Breast Cancer, Supplementation, Resistance Training, Physical Performance
- Trial name
- CaRTiC (NCT05878106)
- Testing
- Creatine supplementation, Resistance training
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- University of Deusto
Transthyretin Cardiac Amyloidosis
EFICAC-TTR Trial: Exercise and Nutritional Supplementation in Transthyretin Cardiac Amyloidosis
Transthyretin cardiac amyloidosis (TTR-CA) is a systemic cardiac disease that predominantly affects older adults and is frequently associated with reduced physical capacity, muscle weakness, frailty, and impaired quality of life.
- Trial name
- EFICAC-TTR (NCT07343999)
- Testing
- Home-Based Multicomponent Exercise Program, Microcrystalline Cellulose Control Supplementation, Creatine and HMB Supplementation
- Where
- 3 sites in Spain
- Volunteers
- 47 people
- Sponsor
- Universidad de Burgos
Tourette Syndrome
Magnetic Resonance Spectroscopy to Evaluate Tourette s Syndrome
This study will use magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) of the brain to try to gain a better understanding of the disease process in Tourette s syndrome, a neuropsychiatric disorder…
- Trial name
- NCT00030953
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Knee Osteoarthritis, Fibromyalgia
Effects of Creatine Supplementation in Women With Knee Osteoarthritis and Fibromyalgia
The purpose of this study is to determine whether creatine associated or not to exercise training can improve physical performance in patients with knee osteoarthritis and fibromyalgia.
- Trial name
- NCT00749983
- Testing
- Creatine supplementation, Dextrose supplementation
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo
Copd, Athletes
Effects of CreaSafe® on Kidney, Muscle, and Cardiopulmonary Function in Athletes and COPD Patients
Creatine supplementation (CS) offers numerous health benefits, with no proven side effects reported to date. CS positively impacts all organs and systems of the body.
- Trial name
- NCT06991426
- Testing
- CreaSafe® creatine
- Where
- Brazil
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Stroke
Creatine Supplementation During Resistance Training for People Recovering From Stroke
Creatine monohydrate is important for sustaining phosphocreatine stores in tissues such as muscle and brain. Phosphocreatine is an important source of energy in these tissues.
- Trial name
- NCT03941678
- Testing
- Creatine monohydrate
- Where
- 2 sites in Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan