Clinical trials: Creatine
Rock Climbing
CAN CREATINE SUPPLEMENTATION IMPROVE PERFORMANCE in ROCK CLIMBERS?
Why? Bouldering is a form of rock climbing that comprises short rock climbs of approximately three metres in height. Approximately 35,000 people participate in bouldering the UK, 200 of whom do so competitively.
- Trial name
- NCT06832423
- Testing
- Creatine monohydrate
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bangor University
Ageing
PRecision gerOMedicinE: Tailored Healthy agEing With Lifestyle, sUpplements and drugS (PROMETHEUS)
As the population ages, the growing prevalence of age-related diseases is creating substantial challenges for healthcare systems worldwide.
- Trial name
- PROMETHEUS (NCT07451496)
- Testing
- Sleep and dietary counseling, Supervised exercise and exergaming program, Motivational interviewing
- Where
- Singapore
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Aging, Supplementation
Aquatic Power Training Dosing Strategies and Creatine Supplementation in Older Adults
This randomized controlled trial will investigate the effects of different aquatic power training dosing strategies and creatine supplementation on functional and multisystem adaptations in community-dwelling older adults.
- Conditions
- Aging, Supplementation, Exercise
- Trial name
- NCT07914270
- Testing
- Time-Based Aquatic Power Training + Creatine, Sedentary Control + Creatine
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- University of Valencia
Delayed-Onset Muscle Soreness (DOMS), Exercise-induced Muscle Damage
TENS Versus Foam Rolling for Muscle Recovery After Eccentric Exercise in Elite Female Volleyball Players
Purpose: This study compared two recovery methods-transcutaneous electrical nerve stimulation (TENS) and foam rolling (FR)-for muscle recovery after intense exercise in elite female volleyball players.
- Conditions
- Delayed-Onset Muscle Soreness (DOMS), Exercise-induced Muscle Damage, Muscle Recovery, Athletic Injuries
- Trial name
- TENS-FR-VB (NCT07438197)
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS), Foam Rolling (FR)
- Where
- Iran
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sistan and Baluchestan
Hematologic Test
Effects of HIIT on Plasma Volume and Aerobic Capacity in Obese Adolescent Girls
The goal of this clinical trial is to investigate the impact of high-intensity interval training (HIIT) program on body composition, hematological parameters, plasma volume variations (PVV), muscle damage markers, and aerobic…
- Trial name
- NCT07046520
- Testing
- High intensity interval training
- Where
- Tunisia
- Volunteers
- 28 people
- Sponsor
- High Institute of Sports and Physical Education of Kef
Spinal Cord Injuries
Creatine or Vitamin D Supplementation in Persons With Spinal Cord Injury Undergoing Resistance Training
The purpose of this study is to determine the effects of creatine monohydrate or vitamin D supplementation on strength gains following a traditional resistance training program for adults with spinal cord injury.
- Trial name
- NCT02099357
- Testing
- Creatine, Vitamin D
- Where
- 2 sites in Portugal
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Type 2 Diabetes Mellitus
Effect of a Protein-Creatine-Omega3-Vitamin D Supplement on Glycemic Variability in Mexican Patients With Type 2 Diabetes
This study aims to evaluate the effect of a daily nutritional supplement containing whey protein, creatine, omega-3 fatty acids, and vitamin D on blood sugar fluctuations in adults with recently diagnosed type 2 diabetes.
- Trial name
- PROVID-DM (NCT06920667)
- Testing
- Protein-Creatine-Omega-3-Vitamin D Supplement
- Volunteers
- 40 people
- Sponsor
- Héctor Iván Saldívar Cerón
Perimenopause
High Intensity Resistance Training + Creatine in Perimenopause
Purpose: The aims of the study are to investigate the effects of high-intensity resistance training (HIRT) with or without creatine monohydrate (CM) supplementation on three key areas: muscle characteristics, brain health, and…
- Trial name
- PERIHIRT (NCT07027800)
- Testing
- Creatine Monohydrate
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of North Carolina, Chapel Hill
Aging
Effects of Resistance-band Training and Creatine Supplementation Strategies in Healthy Older Adults
The primary purpose is to compare the effects of creatine supplementation (bolus ingestion of 5 grams vs. 3 grams) during 16 weeks of resistance-band training on measures of body composition (i.e., whole-body lean tissue mass…
- Trial name
- NCT06606704
- Testing
- Creatine Bolus 5, Creatine Bolus 3, Creatine Intermittent 5
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Regina
Acute Kidney Injury, Exertional Heat Illness
Effects of Creatine Supplementation on Cognitive Measures and Markers of Acute Kidney Injury After Exercise in the Heat
The goal of this clinical trial is to learn if one week of creatine monohydrate supplementation alters inflammation, markers of acute kidney injury (AKI) risk, and cognitive performance in active, young, healthy volunteers.
- Trial name
- NCT07472426
- Testing
- Creatine Monohydrate
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Northern Iowa
Brain Injury Traumatic Mild
Evaluation of the Impact of a Dietary and Nutritional Intervention on Persistent Post-concussive Symptoms
Concussions affect thousands of Canadians every year. Although the effects are usually temporary, 10-15% of adults experience persistent symptoms likely to last several weeks or even months.
- Trial name
- NCT05589064
- Testing
- Experimental: Dietetic counseling, Active Comparator: Omega-3, vitamin D3 and creatine monohydrate, Other : Physiotherapy treatment
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Universite de Moncton
Neurocognitive Disorders, Postoperative Delirium
Creatine and Perioperative Brain Health
The overall goal of this study is to explore the effects of perioperative oral creatine supplementation on cognitive function and physiological responses to surgery in older adults.
- Conditions
- Neurocognitive Disorders, Postoperative Delirium, Postoperative Outcomes
- Trial name
- CREATE (NCT07310043)
- Testing
- Creatine monohydrate
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Dialysis; Complications, Performance Enhancing Product Use
Effects of Short Term Creatine Supplementation in Hemodialysis Patients
Adult patients undergoing chronic dialysis therapy for at least three months were selected. A physical function assessment was conducted, including the Short Physical Performance Battery (SPPB) and a handgrip strength test.
- Trial name
- NCT07033611
- Testing
- Creatine
- Where
- Chile
- Volunteers
- 18 people
- Sponsor
- Carla Basualto Alarcón
Non-small Cell Lung Cancer
Pemetrexed in Maintenance in Patients With Impaired Renal Function, 2 Dose Calculation Strategies
Pemetrexed is used in the treatment of non-small cell lung cancer (NSCLC). Its elimination is mainly renal and its nephrotoxicity requires an interruption of treatment when the CrCLCG falls below 45 mL / min.
- Trial name
- PKAPIR (NCT03607149)
- Testing
- Pemetrexed
- Where
- 3 sites in France
- Volunteers
- 11 people
- Sponsor
- Centre Georges Francois Leclerc
Bipolar I Disorder, Psychosis
Ketogenic and Nutritional Interventions for First Episode Bipolar Disorder
This is a randomized, controlled clinical trial to assess the effects of the ketogenic diet in combination with treatment as usual on brain energy metabolism and psychiatric symptoms in individuals with first episode bipolar…
- Conditions
- Bipolar I Disorder, Psychosis, Schizoaffective Disorder
- Trial name
- NCT06221852
- Testing
- Ketogenic diet, Dietary Guidelines for Americans
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mclean Hospital
Fatigue
The Effects of Nutritional Supplementation on Occupational Performance in Firefighters
The purpose of this study was to assess the usefulness of protein and carbohydrate supplementation, with and without creatine, on occupational performance in firefighters.
- Trial name
- NCT06172543
- Testing
- Creatine Monohydrate, Control
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ward Dobbs
Sarcopenia
Creatine-Guanidinoacetic Acid Supplementation for Sarcopenia (CREGAAS)
Sarcopenia-driven brain and muscle creatine deficit could be seen as a distinctive pathological facet of this condition, and this might be approached with targeted therapies in aim to restore creatine homeostasis in target…
- Trial name
- CREGAAS (NCT04652921)
- Testing
- Creatine-guanidinoacetic acid, Inulin
- Where
- Serbia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Novi Sad, Faculty of Sport and Physical Education
Parkinson's Disease
NET-PD LS-1 Creatine in Parkinson's Disease
The purpose of this trial is to determine if the nutritional supplement creatine slows the progression of Parkinson's disease over time.
- Trial name
- NCT00449865
- Testing
- creatine
- Where
- 50 sites in United States, Canada
- Volunteers
- 1,741 people
- Sponsor
- University of Rochester
Tyrosol, Creatine
The Effects of Tyrosol and Creatine on Endurance, Strength, and Fatigue Resistance in Healthy Adults
The purpose of this clinical trial is to look at tyrosol's effects on endurance, strength, and fatigue resistance in humans. Additionally, the combination of tyrosol and creatine monohydrate will also be looked at to determine if…
- Conditions
- Tyrosol, Creatine, Endurance Performance, Cognition
- Trial name
- NCT06883292
- Testing
- Tyrosol, Creatine, Resistant Dextrin
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Health Behavior
Creatine Supplementation and Resistance Training in Premenopausal Females
The goal of this clinical trial is to determine the effects of creatine monohydrate and resistance training on lean mass, sleep, muscular strength, and perceived menstrual cycle symptoms in untrained premenopausal females.
- Trial name
- NCT05745870
- Testing
- Creatine Monohydrate Supplementation
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Idaho