Clinical trials: Creatine
Muscular Dystrophy, Duchenne
Creatine and Glutamine in Steroid-Naive Duchenne Muscular Dystrophy
This study will help to determine the effectiveness of glutamine and creatine as a possible therapy for DMD. Boys with DMD who are enrolled in this trial will be randomly chosen to receive creatine monohydrate or glutamine or an…
- Trial name
- NCT00016653
- Testing
- Creatine Monohydrate, Glutamine
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Cooperative International Neuromuscular Research Group
Male Infertility
Supplementation for Male Subfertility
Old age, obesity, physical inactivity, environmental factors and genetics may contribute negatively to fertility in both males and females.
- Trial name
- FertEnhancer (NCT06091969)
- Testing
- Active multi-ingredient supplement (Fertility Enhancer, FE)
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Dietary Modification
Creatine, Carnitine and Carnosine in Vegetarians
Balanced vegetarian diets are popular and contain health-promoting characteristics. A balanced lacto-ovo-vegetarian diet differs in nutrient intake from an omnivorous diet, e.g.
- Trial name
- NCT03194334
- Testing
- Vegetarian diet, creatine, Beta-alanine
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Ghent
Endothelial Dysfunction, Hyperhomocysteinemia
Effects of Oral Supplementation With Creatine on Systemic Microvascular Endothelial Function in Vegetarian Individuals
The present study aims at investigating the effects of the oral supplementation with creatine on the systemic microvascular reactivity and plasma levels of homocysteine in vegetarian individuals of the vegan type.
- Trial name
- NCT02961972
- Testing
- monohydrate and micronized creatine
- Where
- Brazil
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- National Institute of Cardiology, Laranjeiras, Brazil
Cancer, Malignant Neoplasm
Measuring Changes in Body Composition and Physical Function in Patients With Childhood Cancers
The primary objective of this study is to evaluate the feasibility and acceptability of obtaining repeated measurements of lean muscle mass, physical function, and biological aging in children receiving active cancer therapy.
- Trial name
- NCT05823740
- Testing
- Bioelectrical impedance Analysis (BIA), D3-Creatine Dilution (D3Cr), 6-Minute Walk Test (6MWT)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Major Depressive Disorder
5-HTP and Creatine for Depression
This is a three-armed clinical trial examining the effect of 5-hydroxytryptophan and creatine monohydrate as augmenting agents for the treatment of depression.
- Trial name
- NCT04395183
- Testing
- 5-Hydroxytryptophan 100 MG, Creatine monohydrate
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Utah
Schizophrenia
Creatine Treatment in Psychiatric Disorders
Creatine plays a pivotal role in brain energy homeostasis. Creatine supplementation is widely used in enhancing sports performance, and has been tried in the treatment of neurological, neuromuscular and atherosclerotic disease…
- Trial name
- NCT00140192
- Testing
- creatine
- Where
- Israel
- Volunteers
- 12 people
- Sponsor
- Beersheva Mental Health Center
Myotoxicity
CPK Levels After LC and Association With Analgesic Modalities
Regional anesthesia and analgesia technics are widely and securely used during general surgery procedures. Interfascial plane blocks are the latest used ones for analgesia.
- Trial name
- NCT06508177
- Testing
- İnterfascial plane block, Standart analgesia plan
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Samsun University
Prostaglandin E1, Percutaneous Coronary Intervention
Protective Effect of Lipo-PGE1 on Myocardial Injury Following Percutaneous Coronary Intervention
we hypothesized that periprocedural treatment with intravenous lipo-PGE1 may reduce myocardial injury and improve clinical outcomes in patients undergoing PCI.
- Trial name
- PGEACS (NCT01245855)
- Testing
- lipo-PGE1
- Where
- China
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Creatine Supplementation, Exercise Ergogenics
Effects of 7-Day Creatine Supplementation on Cognitive Function After High-Intensity Interval Training in Active Young Men
This study evaluates whether 7-day creatine monohydrate supplementation affects cognitive function after high-intensity interval training (HIIT) in active young men.
- Trial name
- HIITCRECOG (NCT07534293)
- Testing
- Creatine Monohydrate, High Intensity Interval Training
- Where
- Indonesia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universitas Negeri Malang
Autism Spectrum Disorder
Creatine Supplementation in Autism Spectrum Disorder
Autism Spectrum Disorder (ASD) is accompanied by reduced levels of total creatine in right temporal-parietal junction and other brain regions of interest, and addressing this deficit by exogenous administration of creatine may…
- Trial name
- CREATOR (NCT04498078)
- Testing
- Creatine
- Where
- Serbia
- Volunteers
- 20 people
- Sponsor
- University of Novi Sad, Faculty of Sport and Physical Education
Creatine
Changing in Plasma Concentration of a New Form of Creatine
Creatine is one of the most popular supplements among athletes. Studies have consistently shown that creatine supplementation increases intramuscular creatine concentrations, improving exercise performance and/or enhancing…
- Trial name
- NCT07838805
- Testing
- New Formulation of Creatine (Creamix), Active Comparator: Creatine Monohydrate
- Where
- Italy
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Padova
Healthy, Creatine Supplementation
Creatine Supplementation and Cognitive and Physical Tests
To assess whether brain creatine availability has an effect on cognition. To do so we will seek to increase brain creatine concentration via a creatine supplementation protocol.
- Trial name
- CREA (NCT03352128)
- Testing
- Creatine, Calcium lactate
- Where
- Belgium
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Osteoporosis, Sarcopenia
Effect of Creatine Supplementation and Exercise on Bone Health
Osteoporosis is an important health problem, costing the Canadian health care system over $2 billion per year. Loss of bone mineral and bone fragility is especially prevalent in postmenopausal women.
- Trial name
- NCT02047864
- Testing
- Creatine monohydrate
- Where
- 2 sites in Canada
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Bipolar I Disorder, Current Episode Depressed
Creatine Monohydrate as Adjuvant Therapy for Bipolar Depression
The purpose of this study is to determine whether creatine monohydrate is effective as an adjuvant treatment for bipolar depression.
- Trial name
- NCT01655030
- Testing
- creatine monohydrate
- Where
- Brazil
- Volunteers
- 44 people
- Sponsor
- University of Sao Paulo
High Blood Arsenic Due to Chronic Arsenic Exposure
Folic Acid and Creatine as Therapeutic Approaches for Lowering Blood Arsenic
The purpose of this study is to determine whether folic acid, alone or together with creatine supplementation, can lower blood arsenic concentrations and improve the ability to detoxify arsenic.
- Trial name
- FACTA (NCT01050556)
- Testing
- folic acid, creatine, creatine + folic acid
- Where
- Bangladesh
- Volunteers
- 600 people
- Sponsor
- Columbia University
Spinal Muscular Atrophy, Fragile X Syndrome
Early Check: Expanded Screening in Newborns
Early Check provides voluntary screening of newborns for a selected panel of conditions. The study has three main objectives: 1) develop and implement an approach to identify affected infants, 2) address the impact on infants and…
- Conditions
- Spinal Muscular Atrophy, Fragile X Syndrome, Fragile X - Premutation, Duchenne Muscular Dystrophy
- Trial name
- NCT03655223
- Testing
- Confirmatory Testing
- Where
- United States
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- RTI International
Exercise, Physical Performance
Examination of Certain Blood Parameters Following Performance and Acute Exercise at Specific Times of the Day
This study aims to investigate whether the time of day at which acute exercise is performed influences physical performance and acute hormonal and biochemical responses in healthy young male soccer players.
- Conditions
- Exercise, Physical Performance, Circadian Rhythm
- Trial name
- Acute & Blood (NCT07825740)
- Testing
- Standardized Acute Exercise Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Firat University
Muscle Weakness
Delivra Topical Creatine for Improving Muscular Power
Creatine is a nutritional supplement that is often ingested to improve exercise performance. The advent of a new product that is applied to the skin overlying muscle offers potential benefit, if the creatine can be targeted to…
- Trial name
- NCT02960425
- Testing
- Delivra TM Livsport preworkout cream
- Where
- 3 sites in Canada
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Healthy
Creatine Timing on Resistance Training Adaptations in College Athletes
While the use of creatine monohydrate supplementation and its associated benefits are well researched and supported, the impact of the timing of when creatine is ingested is a highly nuanced topic.
- Trial name
- NCT05451498
- Testing
- Creatine, Maltodextrin
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Rocky Mountain University of Health Professions