Clinical trials: Creatine Supplementation
Heart Failure
Clinical Prospective ranDomized Trial to Evaluate the Non-inferiority of Left Bundle Branch Area Pacing Vs Cardiac ResynchronIzatioN Therapy With ECG guIded AV Optimization
Cardiac resynchronization therapy is the gold standard therapy for patients with advanced HF left ventricle dysfunction and large QRS.
- Trial name
- DA VINCI (NCT07107048)
- Testing
- Pacemaker and defibrillator
- Where
- Italy
- Volunteers
- 194 people
- Sponsor
- Leonardo Calò, MD
Sarcopenia in Elderly
Effects of Resistance-band Training and Creatine and Whey Protein
The primary purpose of this research is to compare the effects of creatine monohydrate and/or whey protein supplementation during the first 10 weeks of a 20-week resistance-band training program on measures of body composition…
- Trial name
- NCT06606717
- Testing
- Creatine Whey Protein, Whey Protein
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Regina
Fibromyalgia
Effectiveness of Creatine on Pain, Fatigue, and Muscle Architectural Variables in Patients Witg Fibromyalgia.
Creatine, a non-protein organic amino acid, is synthesized from arginine, glycine, and methionine. The use of creatine has been shown to be effective in healthy subjects, providing benefits primarily in terms of strength, which…
- Trial name
- SECPFMAPFM (NCT06675708)
- Testing
- Creatine, Dextrose
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Camilo Jose Cela University
Sarcopenia
Estimation of Muscle Mass in Older Adults Using Deuterated Creatine
Current methods for the quantification of muscle mass are indirect, lack precision, and often rely on expensive equipment that only provides limited (indirect) data on whole body muscle mass.
- Trial name
- MM-DC (NCT02062086)
- Testing
- deuterated creatine 30 mg
- Where
- France
- Volunteers
- 33 people
- Sponsor
- University Hospital, Toulouse
Healthy
Pomegranate Improve Biological Recovery Kinetics in Elite Weightlifter
From the recent scientific literature in the field of biological response to physical exercise, a significant increase in muscle damage, soreness and inflammation were registered immediately and even 48 after resistance exercise.
- Trial name
- NCT02697903
- Testing
- Natural Pomegranate Juice
- Where
- Tunisia
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- The Higher Institute of Sport and Physical Education of Sfax
Ischemic Heart Disease
Creatine, D-Ribose, B1 Vitamin, and B6 Vitamin in Ischemic Heart Disease
Recently, researchers have paid attention to the development of new products such as supplements food and nutraceuticals for identify and develop integrative therapies to be used in cardiovascular disease.
- Trial name
- NCT03411369
- Testing
- Creatine, D-Ribose, B1 Vitamin, and B6 vitamin
- Volunteers
- 55 people
- Sponsor
- University of Pavia
Cold-water Immersion, Protein-carbohydrates Supplementation
Effects on CK, RPE, VAS Scale and Physical Performance of Three Recovery Methods in Elite Basketball Players
The aim of this study was to compare the effects of cold water intermittent ion (CWI), carbohydrate and protein supplementation (SUPPL), and active recovery (ACT) on creatine kinase (CK), perceptual and performance markers of…
- Conditions
- Cold-water Immersion, Protein-carbohydrates Supplementation, Active Recovery, Placebo
- Trial name
- NCT05805540
- Testing
- Cold-water immersion, Protein-carbohydrates supplementation, Active recovery
- Where
- Spain
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Cadiz
Heart Valve Diseases
Sodium Creatine Phosphate in Heart Valve Surgery
To explore the effect of intraoperative sodium creatine phosphate on myocardial protection in patients undergoing valve surgery
- Trial name
- NCT03186053
- Testing
- sodium creatine phosphate, saline
- Where
- 2 sites in China
- Volunteers
- 250 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Brain Injury Traumatic Mild
Evaluation of the Impact of a Dietary and Nutritional Intervention on Persistent Post-concussive Symptoms
Concussions affect thousands of Canadians every year. Although the effects are usually temporary, 10-15% of adults experience persistent symptoms likely to last several weeks or even months.
- Trial name
- NCT05589064
- Testing
- Experimental: Dietetic counseling, Active Comparator: Omega-3, vitamin D3 and creatine monohydrate, Other : Physiotherapy treatment
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Universite de Moncton
Long COVID Fatigue
Exploring the Therapeutic Effects of Creatine Supplementation for Long COVID-19
Individuals living with Long COVID often experiencing a degree of undue fatigue after physical or cognitive exertion secondary to the condition, timed post-exertional malaise 9PEM).
- Trial name
- NCT06992414
- Testing
- Creatine monohydrate
- Volunteers
- 24 people
- Sponsor
- University of Calgary
Safety of Short Term Creatine Hydrochloride Dosing
Short-Term Safety of Low-Dose Creatine Hydrochloride: A 28-Day Single-Arm Pilot Study
Background: Creatine monohydrate (typically 5-20 g/day) has a well-established safety profile across diverse populations. Creatine hydrochloride (CR-HCl) is a highly soluble creatine formulation that may allow effective…
- Trial name
- NCT07521059
- Testing
- creatine supplementation
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Vireo Systems, Inc.
Rhabdomyolysis, Myopathy
Study of the Causes of the Breakdown of Muscle Fibers in Hospitalized Patients
1. Analyze the various causes of breakdown of muscle fibers in hospitalized patients. 2. Analyze the characteristics of these patients in Taiwan (including the drugs history, risk factors and the incidence of complications).
- Conditions
- Rhabdomyolysis, Myopathy, Acute Renal Failure, Neuroleptic Malignant Syndrome
- Trial name
- NCT01022450
- Where
- Taiwan
- Volunteers
- 2,500 people
- Sponsor
- National Taiwan University Hospital
Cognition, Aging
Creatine Supplementation and Cognition
Resistance training as well as creatine supplementation may be beneficial for cognitive function, such as memory and attention. Therefore, the investigators speculate that resistance training combined with creatine…
- Trial name
- NCT01164020
- Testing
- creatine supplementation, Resistance training
- Where
- Brazil
- Volunteers
- 56 people
- Sponsor
- University of Sao Paulo
Endothelial Dysfunction, Oxidative Stress
Creatine Monohydrate Supplementation and Vascular Endothelial Health
To determine the effects of 4 weeks of creatine monohydrate supplementation on markers of macrovascular and microvascular function, cognitive performance, and physical performance.
- Trial name
- NCT05014659
- Testing
- Creatine monohydrate
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Florida State University
Oligospermia, Sperm Count, Low
Creatine and Ubiquinol for Sperm Quality
This randomized controlled double-blind parallel-group interventional trial explores the impact of 8-week creatine supplementation, with or without ubiquinol, on sperm quality biomarkers in normospermic and oligospermic men.
- Trial name
- CRESPAQ10 (NCT06202469)
- Testing
- Supplement 1, Supplement 2
- Where
- Serbia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Novi Sad, Faculty of Sport and Physical Education
Anaerobic Performance, Sports Nutrition
Pre-Sleep Creatine Enhances Anaerobic Power in Recreationally Active Females
This study is a randomized, double-blind, placebo-controlled trial designed to examine the effects of pre-sleep creatine monohydrate supplementation on anaerobic performance and muscle damage markers in recreationally active…
- Conditions
- Anaerobic Performance, Sports Nutrition, Exercise Recovery, Muscle Fatigue
- Trial name
- SleepCrM (NCT06937190)
- Testing
- Creatine Monohydrate
- Where
- Iran
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Depression, Anxiety
Creatine for Depressed Male and Female Methamphetamine Users
Assess the antidepressant/anxiolytic effect of creatine in male and female methamphetamine users Assess creatine's effect on methamphetamine use Assess the safety of creatine in male methamphetamine users with depression
- Conditions
- Depression, Anxiety, Methamphetamine Dependence
- Trial name
- NCT02568878
- Testing
- Creatine monohydrate
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Montana State University
Healthy Subjects
Effects of Betaine Supplementation on Strength and Muscle Creatine Content
It has been suggested that betaine supplementation may improve muscle strength by increasing muscle creatine content. However, there is no data supporting this assumption.
- Trial name
- NCT01213719
- Testing
- creatine, betaine, dextrose
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Anorexia, Cachexia
Creatine in Treating Patients With Cancer-Associated Weight Loss
RATIONALE: It is not yet known whether the supplement creatine is effective in increasing weight and improving appetite and quality of life in patients who have cancer.
- Conditions
- Anorexia, Cachexia, Unspecified Adult Solid Tumor, Protocol Specific, Weight Changes
- Trial name
- NCT00081250
- Testing
- creatine monohydrate
- Where
- 220 sites in United States
- Volunteers
- 300 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Proteinuria in Pregnancy
The Effect of Blood on the PC Ratio During Pregnancy
This study will examine the effect if blood on the the protein to creatine (PC) ratio in pregnant patients by adding blood to urine samples.
- Trial name
- NCT05434845
- Testing
- Blood draw
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Marshall University