Clinical trials: Critical Care, Intensive Care
Intensive Care Unit-acquired Weakness, Artifical Intelligence
AI Based Muscular Ultrasound to Assess Intensive Care Unit-acquired Weakness
The aim of this observational case-control study is to investigate, whether artificial intelligence can detect ultrasound-derived imaging characteristics typical for intensive care unit-acquired weakness.
- Conditions
- Intensive Care Unit-acquired Weakness, Artifical Intelligence, Ultrasound
- Trial name
- ACTIVATE (NCT06765551)
- Testing
- Neuromuscular Ultrasound
- Where
- Germany
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Jena University Hospital
Malnutrition, Critical Illness
Anabolic Steroids for Nutritional Rehabilitation of Critically Ill Patients
This prospective, double-blinded study will determine the feasibility of determining the efficacy of a weekly intramuscular injection of nandrolone (an anabolic steroid) in malnourished ICU patients.The data from this study will…
- Trial name
- NCT00242463
- Testing
- Nandrolone (anabolic steroid)
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
ICU, Comfort
Comfort Care Bundle
Intensive care units (ICUs) are specialized units where numerous complex treatment and care procedures are applied. In these units, critically ill patients are exposed to stressful conditions and experience significant pain and…
- Conditions
- ICU, Comfort, Bundle Care, Nursing Care
- Trial name
- NCT07366021
- Testing
- Comfort Care Bundle
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
PTSD, Critical Illness
The Experiences of Children and Caregivers Given PICU Storybooks
1. To assess the acceptability and feasibility of a study design aimed at evaluating the efficacy of a newly developed intervention for children and their caregivers following discharge from PICU 2.
- Conditions
- PTSD, Critical Illness, Depression, Anxiety
- Trial name
- NCT04041401
- Testing
- PICU storybook
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Self Efficacy, Nursing Caries
Effectiveness of Delirium Simulation Education of Nurses in Intensive Care Unit
Delirium is a common symptom in the intensive care unit, which greatly affects the prognosis of critically ill patients and increases medical costs.
- Conditions
- Self Efficacy, Nursing Caries, Intensive Care Unit Delirium, Simulation of Physical Illness
- Trial name
- NCT05333354
- Testing
- education strategy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Pediatric ALL, Critical Illness
Singapore's Health Outcomes After Critical Illness in Kids
What is the problem? Every year about 2.5 million children are affected by critical illness and require admission to the pediatric intensive care unit (PICU).
- Conditions
- Pediatric ALL, Critical Illness, Post Intensive Care Unit Syndrome
- Trial name
- SHACK (NCT04637113)
- Testing
- This is a non-interventional study
- Where
- Singapore
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Anxiety, Depression
PARTNER II: Improving Patient and Family Centered Care in Advanced Critical Illness
This is a stepped wedged randomized controlled trial comparing the PARTNER intervention with usual care in 5 Intensive Care Units.
- Trial name
- NCT02445937
- Testing
- PARTNER II
- Where
- 2 sites in United States
- Volunteers
- 848 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Major Injury
Perioperative Research Into Memory: Cognitive Outcome Following Major Burns
The long term survival of patients who require admission to critical care (CC) following a major burn injury (MBI) continues to improve with advanced clinical management.
- Trial name
- PRiMe (NCT03470844)
- Testing
- Face-to-face neurocognitive tests, Psychological screening, fMRI
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Psychosocial Intervention, Intensive Care Units (ICUs)
Study Protocol for a Pilot Randomized Controlled Trial of a Psychosocial Care Intervention in Intensive Care
This Pilot-RCT is part of a feasibility study that aims to learn if the IPS-psychosocial care intervention and an RCT on its efficacy are feasible in patients, relatives and staff on icu wards.
- Conditions
- Psychosocial Intervention, Intensive Care Units (ICUs), Psychosocial Health
- Trial name
- IPS-Pilot (NCT06733493)
- Testing
- integrated psychosocial care
- Where
- 4 sites in Germany
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Harald Gündel
Intensivist, Resident
Physical Activity of Staff on Medical Duty in a Department of Anesthesia and Critical Care During Guards
On-call work is an integral part of senior and junior patricians in a critical care department. Several studies have examined the effect of sleep deprivation on physicians on call and the impact of sleep deprivation on the…
- Conditions
- Intensivist, Resident, Night Work
- Trial name
- AMAC (NCT04567017)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
ARDS
NMR Based Metabolomics Kinetics in ARDS Patients
Acute respiratory distress syndrome (ARDS) is a life-threatening condition requiring respiratory support to maintain oxygenation.
- Trial name
- NCT06036056
- Where
- India
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sanjay Gandhi Postgraduate Institute of Medical Sciences
Critical Illness
Effect of Intensivist Communication on Surrogate Prognosis Interpretation
This study evaluates the effect of physician communication styles on the interpretation of prognosis by family members of chronically-ill patients.
- Trial name
- NCT04239209
- Testing
- Indirect - other patients, Indirect - physiology, Redirection
- Where
- United States
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Critical Care
Montreal Toulouse Test With Eye Tracking in Intensive Care Unit to Evaluate Comprehension
Assessment of the level of oral comprehension of the intensive care patient is essential to improve their care because they have often troubles like delirium.
- Trial name
- MEXICO (NCT05078632)
- Testing
- Montreal-Toulouse Test adapted in eye tracking
- Where
- France
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Critically Ill, Colorectal Surgery
Muscle Function After Intensive Care
Final objective of critical care is no longer only survival. The role of medical and paramedical teams should also be to restore functional capacities, autonomy and quality of life.
- Conditions
- Critically Ill, Colorectal Surgery, Healthy, Muscle Strength
- Trial name
- NCT03922113
- Testing
- Patient follow up
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Liege
Patient Handoff, Healthcare Team
Handoffs and Transitions in Critical Care - Understanding Scalability
The investigators will leverage implementation science and engineering to adapt, implement, and rigorously evaluate tailored postoperative handoff protocols and implementation strategies.
- Conditions
- Patient Handoff, Healthcare Team, Communication, Patient Safety
- Trial name
- HATRICC-US (NCT04571749)
- Testing
- Customized handoff
- Where
- 5 sites in United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Electroencephalogram, Intensive Care Units
Critical Care EEG Course
Knowledge of the basic fundamental skills of electroencephalography would enable medical and nursing staffs to provide efficient and effective bedside EEG monitoring in critically ill patients.
- Conditions
- Electroencephalogram, Intensive Care Units, Teaching Intervention
- Trial name
- NCT03545776
- Testing
- Critical Care EEG Course
- Where
- 6 sites in France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ictal Group
Critically Ill, Extubation
Does Tracheal Suction During Extubation in Intensive Care Unit Decrease Functional Residual Capacity
Little is known about the procedure of extubation of patients admitted in Intensive Care Units (ICU). In particular, effects of tracheal suction during extubation have never been evaluated.
- Conditions
- Critically Ill, Extubation, Intensive Care Unit
- Trial name
- NCT03681626
- Testing
- no tracheal suction, tracheal suction
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Ventilation Modes, Mechanical Ventilation
Effectiveness of Ventilation Modes in Intensive Care: A Comparison of Mandatory Minute Ventilation and Synchronized Intermittant Mandatory Ventilation Using Bioelectrical Impedance Tomography
Synchronized Intermittent Mandatory Ventilation (SIMV) is a commonly used ventilatory mode available in many modern ventilators, frequently applied in intensive care units for patients requiring invasive mechanical ventilation.
- Conditions
- Ventilation Modes, Mechanical Ventilation, Critical Illness, Respiratory Support
- Trial name
- NCT06961227
- Testing
- No investigational intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Harran University
Nurse's Role, Anxiety
Investigation of the Effect of Virtual Reality Software on Nurses' Clinical Practice, Problem Solving and Clinical Decision Making Skills and Anxiety in the Care Management of Intensive Care Patients.
In the light of technological developments, learner-centered methods have begun to replace traditional teaching methods. Simulation applications are increasing in order to ensure patient safety and improve the quality of care in…
- Conditions
- Nurse's Role, Anxiety, Nursing Caries
- Trial name
- NCT05982288
- Testing
- Virtual Reality Software
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Sedated ICU Patients
IMPROVE Critical Care Study (Pilot)
The Pilot Clinical Investigation planned is a prospective, unblinded randomized pilot trial comparing sedation management using a protocol based on responsiveness with standard sedation management.
- Trial name
- NCT01361230
- Testing
- "Sedation Trial Monitor" is the name of the device used.
- Where
- United Kingdom
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- GE Healthcare