Clinical trials: Critical Ill Patients
Cholangitis Infective, Elderly Person
Outcomes of Elderly Patients Admitted to the Intensive Care Unit With Severe Acute Cholangitis
The aging of the population goes along with an increased demand for intensive care among very elderly patients (above 75-80 years old). At the same time, there is a decline in the supply of intensive care units (ICU).
- Trial name
- ANGIOCHOLREA (NCT03831529)
- Where
- 2 sites in France
- Volunteers
- 204 people
- Sponsor
- Central Hospital, Nancy, France
ICU, Critical Illness
Association Between Dynamic Prealbumin Trajectories and Prognosis in Critically Ill Patients
Nutritional support therapy is a crucial part of ICU patient care, as both malnutrition and overnutrition can lead to adverse clinical outcomes. Meticulous monitoring of nutritional support is essential.
- Conditions
- ICU, Critical Illness, Adult
- Trial name
- PAB-TRACK (NCT07414160)
- Testing
- No Intervention: Observational Cohort
- Volunteers
- 500 people
- Sponsor
- The First Hospital of Jilin University
Critical Illness
User Experience of a Telemedicine Platform for the Follow-up of Post Intensive Care Syndrome (PICS)
Survivors of critical illness may present with a set of physical, emotional and cognitive sequelae, known as Post Intensive Care Syndrome (PICS).
- Trial name
- NCT06438380
- Volunteers
- 14 people
- Sponsor
- Corporacion Parc Tauli
Renal Function, Critical Illness
Evaluation of the Optimal Technique for Determination of Renal Function of Critically Ill Patients
The purpose of this study is to evaluate the optimal technique for determination of the renal function of critically ill patients.
- Trial name
- NCT00117390
- Testing
- Measurement of inulin clearance
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- University Hospital, Ghent
Hyperglycemia, Respiratory Failure
A Trial Comparing SGC and Conventional Empiric Treatment for Glucose Control in Critically Ill Patients With Mechanical Ventilation in ICU
Poor glycemic control in critically ill patients can increase their mortality, while safe and efficient glucose control is laborious and time-consuming.
- Conditions
- Hyperglycemia, Respiratory Failure, Critical Illness
- Trial name
- NCT02491346
- Testing
- conventional empirical glycemic control, SGC directed glycemic control
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Peking Union Medical College Hospital
Delivery Complication, Pregnancy Related
Cesarean Delivery Outcomes in Maternal Critical Care
Cesarean delivery in critically ill pregnant women, especially outside the operating room, is a rare but high-risk situation for both mother and fetus.
- Trial name
- CESAREA (NCT07759024)
- Volunteers
- 200 people
- Sponsor
- Société Française d'Anesthésie et de Réanimation
Critical Illness, Metabolism Disorders
Blood-Interstitial Fluid Glucose Gap
Metabolic monitoring is fundamental to guiding nutritional therapy in critically ill patients. Although indirect calorimetry is the established gold standard for measuring resting energy expenditure, its routine clinical use is…
- Trial name
- NCT07240103
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Chinese Medical Association
Critical Illness, Acute Kidney Injury
Outcomes of Critically Ill Patients With Severe Acute Kidney Injury Requiring Renal Replacement Therapy
This study assess the vital status, renal function and renal recovery of patients admitted to intensive care unit and requiring renal replacement therapy for acute kidney failure.
- Trial name
- PROVEER (NCT02897310)
- Where
- France
- Volunteers
- 245 people
- Sponsor
- University Hospital, Brest
Sleep Deprivation, Delirium
Does Nightly Dexmedetomidine Improve Sleep and Reduce Delirium in ICU Patients?
Specific Aims 1. Establish the feasibility of larger trial by implementing a sleep protocol in the ICU at 2 different sites. Specifically will be estimating the recruitment rates of patients and the compliance with both…
- Trial name
- SKY-DEX (NCT01791296)
- Testing
- Dexmedetomidine
- Where
- 2 sites in United States, Canada
- Volunteers
- 100 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Critical Illness, ICU
Effects of Melatonin on Sleep Architecture of Critically Ill Patients in the ICU
This is a pilot study to examine the effects of melatonin on the sleep patterns of critically ill patients. Patients will have their sleep patterns measured with a device attached to their head with a headband then be given a…
- Conditions
- Critical Illness, ICU, ICU Hospitalization, Melatonin
- Trial name
- NCT07691996
- Testing
- Melatonin
- Volunteers
- 30 people
- Sponsor
- Rutgers, The State University of New Jersey
Critical Care Patient; Lower Digestive Tract Disorder;, Colon Lesions;
Acute Non-mechanical Lower Digestive Tract Disorders Should Distinguish Whether Colonic Lesions or Not in Critically Ill Patients
The purpose of the study is to investigate acute non-mechanical lower digestive tract disorders should distinguish whether colonic lesions or not in critically ill patients
- Trial name
- NCT01919060
- Volunteers
- 69 people
- Sponsor
- Nanjing PLA General Hospital
Critically Ill Patients, Acid-Base Disturbance
Bicarbonate Variation Monitoring With Indirect Calorimetry
Patients admitted to the intensive care unit frequently exhibit abnormal blood bicarbonate levels. These abnormalities are associated with patient outcomes and often prompt clinicians to modify management, either diagnostically…
- Conditions
- Critically Ill Patients, Acid-Base Disturbance, Indirect Calorimetry
- Trial name
- BICAR-CC (NCT07782658)
- Testing
- Indirect calorimetry measurement
- Where
- France
- Volunteers
- 91 people
- Sponsor
- Hospices Civils de Lyon
Respiratory Distress Syndrome, Acute, Respiratory Insufficiency
Bioelectrical Impedance in Monitoring Hyperhydration and Polyneuromyopathy in Critically Ill Patients
This prospective, blinded observational clinical study was aimed to determine the effect of hyperhydration and muscle loss measured by Bioelectrical impedance vector analysis (BIVA) on mortality.
- Conditions
- Respiratory Distress Syndrome, Acute, Respiratory Insufficiency, Lung Ventilator, Hyperhydration
- Trial name
- NCT05991778
- Testing
- Bioelectrical impedance vector analysis (BIVA), Blood and urine analysis, cumulative water balance
- Where
- Czechia
- Volunteers
- 61 people
- Sponsor
- University Hospital Ostrava
Hyperglycemia, Hypoglycemia
Continuous Subcutaneous Glucose Monitoring in Critical Patients
This is a single-center, observational, descriptive, longitudinal, and prospective study This study aims to determine the cumulative incidence during admission and the incidence rate of potential hypoglycemic events (defined as…
- Conditions
- Hyperglycemia, Hypoglycemia, Diabetes, Critical Care
- Trial name
- NCT06234787
- Where
- Spain
- Volunteers
- 245 people
- Sponsor
- Universidad Europea de Madrid
Critical Illness, Nutritional and Metabolic Disease
Diarrhea and Stipsis in Critically Ill Patients (NUTRITI)
This study prospectively observed the complications intended as diarrhea or sti-sis that critically ill patients developed within 7 days after ICU admission.
- Conditions
- Critical Illness, Nutritional and Metabolic Disease, Nutritional Deficiency, ICU Acquired Weakness
- Trial name
- NUTRITI (NCT05473546)
- Testing
- ARTIFICIAL NUTRITION
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Azienda Sanitaria-Universitaria Integrata di Udine
Critically Ill
Metabolic and Nutritional Characteristics of Long-stayer ICU Patients
The intensive care (ICU) patient population has increasing number of very long ICU stays. Long-stayers are usually defined as requiring more than 1 week of mechanical ventilation and of ICU therapy: little is know about their…
- Trial name
- Nutri-ICU-LS (NCT03938961)
- Where
- Switzerland
- Volunteers
- 205 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Delirium
The Effect of Guanfacine on Delirium in Critically Ill Patients
Delirium in patients in the intensive care unit (ICU) is a common problem associated with increased mortality and morbidity, including increased hospital and ICU length of stay, greater hospital cost, increased ventilator days…
- Trial name
- NCT04578886
- Testing
- Guanfacine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Alabama at Birmingham
Critical Illness, Enteral Nutrition
TAK-954 in Critically Ill Participants With Enteral Feeding Intolerance (EFI)
The purpose of this study is to assess the treatment effect of intravenous TAK-954 in improving the average daily protein adequacy received through enteral nutrition in critically-ill participants developing EFI.
- Conditions
- Critical Illness, Enteral Nutrition, Enteral Feeding Intolerance
- Trial name
- NCT03477903
- Testing
- TAK-954, Metoclopramide, Normal Saline
- Where
- 44 sites in United States, Australia and 2 more
- Volunteers
- 1 people
- Sponsor
- Millennium Pharmaceuticals, Inc.
Acceptability of Health Care
Closed-blood Sampling Devices in the Adult Critically Ill Patient
Based on the hypothesis that the strategy of using Closed-Blood Sampling Devices (CSBD, experimental group) compared to the usual practice (waste discard volume, control group), in critically ill adult patients, will decrease the…
- Trial name
- NCT06478160
- Testing
- Closed-Blood Sampling Devices, Waste discard volume
- Where
- 3 sites in Spain
- Volunteers
- 216 people
- Sponsor
- University of Barcelona
Critically Ill, Acute Respiratory Distress Syndrome
the Influence of Tidal Volume to Lung Strain
Measure the lung strain in different tidal volume in ADRS patients to find the relationship between tidal volume and lung strain and find the most suitable tidal volume for each patient.
- Trial name
- NCT01864668
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Zhongda Hospital