Clinical trials: Critical Illness, completed
Acute Respiratory Failure, Critical Illness
"VARIABLE-PSV" Study
Variable PSV is a new ventilatory mode which delivered a pressure support "variable" from 0 to 100% variation of the set PSV level.This study aimed to compare the ventilatory behavior, sleep quality and gas exchange between…
- Conditions
- Acute Respiratory Failure, Critical Illness, Ventilation Weaning
- Trial name
- NCT01580956
- Testing
- VARIABLE-PSV ventilatory mode, STANDARD-PSV ventilatory mode
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Montpellier
Critical Illness, Pediatrics
Comparing Cardiac Output Measurements in Critically Ill Children Using USCOM and Transthoracic ECHO
The purpose of this study is to compare the accuracy and precision of two non-invasive methods of measuring cardiac output in critically ill children (<18 yrs).
- Trial name
- NCT01460329
- Testing
- Ultrasonic Cardiac Output Monitor (USCOM).
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of North Carolina, Chapel Hill
Critical Illness
The Pain in Intensive Care Unit: Different Rating System Comparing
The purpose of this research is to find the best system for assessing the pain of critically ill patient in Intensive Care Unit (ICU).
- Trial name
- ICPain (NCT01669486)
- Testing
- CPOT, BPS
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Università degli Studi dell'Insubria
Critically Ill
Impact of SPN on Infection Rate, Duration of Mechanical Ventilation & Rehabilitation in ICU Patients
Rationale: Enteral nutrition (EN) in the intensive care (ICU) patients is recommended as a standard of care. However, EN alone is often associated with insufficient energy intakes and increased complication rates.
- Trial name
- NCT00802503
- Testing
- SPN
- Where
- 2 sites in Switzerland
- Volunteers
- 305 people
- Sponsor
- University Hospital, Geneva
Anemia
A Study to Observe the Causes and Treatment of Anemia in Critically Ill Children
The purpose of this study is to determine the incidence of anemia and blood transfusions and management of these in critically ill children
- Trial name
- NCT00211055
- Volunteers
- 1,201 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Critically Ill
The Correlation Between B-type Natriuretic Peptide (BNP) and Global End Diastolic Volume
The investigators hypothesized that the serum B-type Natriuretic Peptide (BNP) level may be correlated with global end diastolic volume (GEDV) as measured by transpulmonary thermodilution technique (PiCCO).
- Trial name
- NCT01344265
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Jinhua Central Hospital
Critical Illness
Combining Objective and Subjective Sedation Assessment Tools
The purpose of this study is to determine if the use of a device called the BIS monitor in addition to the Richmond Agitation Sedation Scale will give better assessment of a subject's level of sedation.
- Trial name
- COST_2 (NCT00734409)
- Testing
- Bispectral Index (BIS) Monitor
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Duke University
Critical Illness
Glucose Control in the ICU Using Continuous Glucose Monitoring
Stress hyperglycemia occurs in 50-85% of patients admitted to a medical intensive care unit (MICU) and is associated with increased morbidity and mortality.
- Trial name
- REGIMEN (NCT01799512)
- Testing
- experimental: real-time continuous glucose monitoring, Active comparator: blinded continuous glucose monitoring
- Where
- 2 sites in Belgium
- Volunteers
- 35 people
- Sponsor
- University Hospital, Antwerp
Pressure Sores, Intensive Care
The Effect of Antioxidants on the Immune Response and Wound Healing in Critically Ill Patients
The purpose of this study is to investigate whether the addition of omega-3 and antioxidants to nutritional support in critically ill patients in the intensive care unit influences the immune and anti-inflammatory systems and so…
- Trial name
- NCT00487097
- Testing
- Eicosapentanoic acid, docosahexaenoic acid
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Rabin Medical Center
Positive-Pressure Respiration, Intrinsic, Critically Ill Patients
A New Monitor to Measure Dermal Blood Flow in Critically Ill Patients: a Preliminary Study
Background: Conditions of reduced perfusion are characterized by redistribution of blood flow away from the skin to more vital organs.
- Trial name
- MDBF-CIP (NCT01794468)
- Testing
- Dermal blood flow measurements
- Where
- Israel
- Volunteers
- 11 people
- Sponsor
- Rabin Medical Center
Critical Illness, Dietary Modification
Probiotics in Enteral Feeding in Critically Ill Patients
The purpose of this study is to investigate the effect of probiotics in enteral nutrition on improving gut function, inflammatory markers and clinical outcomes in critically ill patients admitted to the intensive care unit.
- Conditions
- Critical Illness, Dietary Modification, Probiotics, Gut Failure
- Trial name
- NCT01792401
- Testing
- Probiotics
- Where
- Malaysia
- Volunteers
- 49 people
- Sponsor
- University of Malaya
Thoracic Surgery, Cardiac Surgery
Comparison of Two Potassium Targets Within the Normal Range in Intensive Care Patients
Rationale: It is well known that distinctly abnormal blood potassium values can cause serious complications such as cardiac arrhythmias.
- Conditions
- Thoracic Surgery, Cardiac Surgery, Critically Ill
- Trial name
- GRIP-COMPASS (NCT01085071)
- Testing
- Potassium Chloride
- Where
- Netherlands
- Volunteers
- 1,225 people
- Sponsor
- University Medical Center Groningen
Critical Illness
Daily Checklists and Outcome in the Intensive Care Unit
Medical errors account for tens of thousands of deaths and tens of billions of dollars in healthcare costs in the United States every year.
- Trial name
- NCT01396044
- Testing
- Electronic checklist, Verbal prompting
- Where
- 2 sites in United States
- Volunteers
- 451 people
- Sponsor
- Northwestern University
Delirium, Critical Illness
Pilot Study of Haloperidol to Treat Critical Illness Delirium
The goal of this study is to determine whether haloperidol reduces the time on the breathing machine in critically ill patients with delirium.
- Trial name
- NCT00429676
- Testing
- Haloperidol
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Colorado, Denver
Critical Illness
Prevalence of Microcirculatory Alterations in Intensive Care Patients
Recent research has focused on the investigation of sublingual microcirculatory alterations in different patient categories, like cardiac surgery and sepsis.
- Trial name
- NCT01179243
- Where
- 4 sites in Netherlands
- Volunteers
- 500 people
- Sponsor
- Frisius Medisch Centrum
Acute Respiratory Failure, Critically Ill
Heparin Binding Protein in Patients With Acute Respiratory Failure Treated With GCSF (Filgrastim)
This is a study of plasma HBP -levels of a previously published trial of G-CSF in critically ill patients (Pettila et al. Critical Care Medicine 2000).
- Trial name
- HBP-Neupogen (NCT01713309)
- Testing
- Filgrastim
- Where
- Finland
- Volunteers
- 59 people
- Sponsor
- Helsinki University Central Hospital
Critical Illness
Study of Arginine Free IED in Critically Ill Patients.
This study intends to investigate the clinical outcomes of a new immunoenhancing formula which composed arginine free compare to isonitrogenous, isocaloric standard formula in ICU patients.The study design is multicenter…
- Trial name
- ROSIED (NCT01713257)
- Testing
- Immunoenhancing diet, Isocaloric, isonitrogenous diet
- Where
- 3 sites in Thailand
- Volunteers
- 172 people
- Sponsor
- Thai Otsuka Pharmaceutical Co., Ltd.
Intubation, Critically Ill
Airway IgA: Respiratory Tract IgA Levels in Critically Ill Intubated Patients
This study will examine the impact of acute illness on sequential airway IgA levels in intensive care patients who will require prolonged intubation.
- Trial name
- NCT00205309
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Wisconsin, Madison
Hyperglycaemia, Hypoglycaemia
Continuous Glucose Monitoring by Subcutaneous Measurement Compared to Frequent Point of Care Measurement by Accu Chek in Critically Ill Patients
The purpose of this study is to evaluate the accuracy and reliability of the continuous glucose monitoring system the FreeStyle Navigator® (Abbott, Diabetes Care) in critically ill patients by comparing subcutaneous measuring…
- Trial name
- RESCUEII (NCT01526044)
- Testing
- Freestyle Navigator
- Where
- Netherlands
- Volunteers
- 178 people
- Sponsor
- Onze Lieve Vrouwe Gasthuis
Acute Pancreatitis
An Observational Study of the Role of Intra-abdominal Pressure Monitoring in Patients With Acute Pancreatitis
Acute pancreatitis is a multi-system disease with an unpredictable clinical course and significant morbidity and mortality Approximately 20% of patients develop multi-organ failure requiring management within a critical care…
- Trial name
- NCT01611532
- Where
- United Kingdom
- Volunteers
- 218 people
- Sponsor
- Emma Aitken