Clinical trials: Critically Ill Surgical Patients
Surgery
Validation of Noninvasive Hemoglobin, Comparison of PVI to Standard Methods, and Validation of Clinical Efficacy of ORI
The study goal is to establish the correlation of hemoglobin values determined by the noninvasive pulse oximetry-determined hemoglobin (SpHb) system with hemoglobin as measured by other validated devices.
- Trial name
- NCT02841397
- Testing
- Masimo Pulse CO-Oximeter
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Masimo Corporation
Nutrition Disorder, Trauma
Supplemental Enteral Protein in Critical Illness
The aim of this study is too determine the effect of enteral protein supplementation on biochemical measures of inflammation and protein metabolism in critically ill surgical patients.
- Conditions
- Nutrition Disorder, Trauma, Critical Illness
- Trial name
- NCT03170401
- Testing
- Protein supplementation, Standard enteral nutrition
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of Washington
Critically Ill
PEP uP Protocol in Surgical Patients
The main objective of this project is to asses for safety, feasibility and effectiveness of an aggressive feeding protocol, PEP uP (Enhanced Protein-Energy Provision via the Enteral Route Feeding Protocol) in increasing protein…
- Trial name
- NCT02459275
- Testing
- PEP uP Protocol, Metoclopramide
- Where
- 4 sites in United States
- Volunteers
- 36 people
- Sponsor
- Clinical Evaluation Research Unit at Kingston General Hospital
Endothelial Dysfunction
Evaluation of Lipid Emulsion on GCX in Critically Ill Patients
Characterisation of the lipidome and parenteral nutrition modulate the endothelial glycocalyx. The aim of the study A is to detect any influence of the lipid emulsion on the endothelial glycocalyx in patients in critical care.
- Trial name
- NCT03216850
- Testing
- Sublingual microcirculation assessment
- Where
- Czechia
- Volunteers
- 15 people
- Sponsor
- University Hospital Hradec Kralove
Critical Illness
Dexmedetomidine Versus Midazolam for Facilitating Extubation
The purpose of this randomized, double-blind study is to evaluate the utility, safety, and cost of transitioning benzodiazepine sedation to dexmedetomidine in medical or surgical intensive care unit (ICU) patients requiring…
- Trial name
- NCT00744380
- Testing
- Midazolam, Dexmedetomidine
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Colorado, Denver
Critical Illness
Glycocalyx Damage in Critically Ill Patients
The hypothesis to be tested: GCX damage and its dynamics correlate to various patient related factors and to using organ-supporting measures. There is a correlation between length of organ support and GCX damage.
- Trial name
- NCT03146585
- Testing
- PBR assessment
- Where
- Czechia
- Volunteers
- 40 people
- Sponsor
- University Hospital Hradec Kralove
Critically Ill, Hypoglycemia
The Efficacy of Glucagon Like Peptide (GLP) - 1(7-36) Amide for Glycemic Control in Critically Ill Patients
The goal of this present proposal is to examine the efficacy of GLP-1 administered to control blood glucose in critically ill patients.
- Trial name
- NCT00798590
- Testing
- Glucagon-Like Peptide-1, Saline
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Johns Hopkins University
Critical Illness
Efficacy and Mechanisms of GLN Dipeptide in the SICU
Relative glutamine (GLN) deficiency may contribute to morbidity and mortality in surgical intensive care unit (SICU) patients. During critical illness, GLN utilization by the immune system, gut mucosa and other tissues exceeds…
- Trial name
- GLND (NCT00248638)
- Testing
- Glutamine dipeptide with 15% Clinisol, 15% Clinisol
- Where
- 5 sites in United States
- Volunteers
- 150 people
- Sponsor
- Emory University