Clinical trials: Crohn's Disease
Inflammatory Bowel Disease, Crohn's Disease
Anti-TNF-alpha Trough Level Measurements in Inflammatory Bowel Disease
Drug serum concentrations will be measured at several time-points for inflammatory disease patients treated with anti-TNF agents.
- Conditions
- Inflammatory Bowel Disease, Crohn's Disease, Ulcerative Colitis
- Trial name
- NCT02073526
- Testing
- Infliximab, adalimumab, certolizumab pegol
- Where
- Norway
- Volunteers
- 1,230 people
- Sponsor
- Oslo University Hospital
Inflammatory Bowel Disease
The EDICT Trial - Therapy for Inflammatory Bowel Disease Flares
Inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), are chronic inflammatory conditions of the gastrointestinal tract that affect millions of people in the United States of America.
- Trial name
- EDICT (NCT07143188)
- Testing
- elemental diet (ED)
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Wake Forest University Health Sciences
Pediatric Crohn's Disease
Clinical Study of TA-650 in Pediatric Patients With Crohn's Disease
The purpose of this study is to evaluate the efficacy of TA-650 using Pediatric Crohn's Disease Activity Index (PCDAI) in pediatric patients with moderate to severe Crohn's disease after TA-650 administration at a dose of 5 mg/kg…
- Trial name
- NCT01580670
- Testing
- TA-650
- Where
- 7 sites in Japan
- Volunteers
- 14 people
- Sponsor
- Tanabe Pharma Corporation
Crohn's Disease
Diagnostic Accuracy of Capsule Endoscopy in Small Bowel Crohn's Disease
Prospective study to compare in a blinded fashion four different diagnostic modalities to detect active small bowel Crohn's disease: a) colonoscopy with ileoscopy; b) small bowel follow through; c) capsule endoscopy; and d)…
- Trial name
- NCT00588653
- Testing
- Capsule endoscopy, CT enterography, colonoscopy, small bowel follow-through
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Mayo Clinic
Ankylosing Spondylitis, Autoimmune Disease
Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors
This study learn how easily patients can use an educational tool that will be created for patients with melanoma and pre-existing autoimmune diseases who receive or will receive immune checkpoint inhibitor drugs.
- Conditions
- Ankylosing Spondylitis, Autoimmune Disease, Crohn Disease, Enteropathic Arthritis
- Trial name
- NCT04751396
- Testing
- Best Practice, Educational Intervention, Interview
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- M.D. Anderson Cancer Center
Crohn Disease
TRansmural hEaliNg Definition in CroHn's Disease (TRENCH 1)
Multicenter prospective cross-sectional study of CD patients, its aim is the construction of an objective and reproducible system for evaluation of Transmural healing in Crohn's Disease (CD).
- Trial name
- TRENCH 1 (NCT05903066)
- Testing
- Magnetic Resonance Enterography (MRE)
- Where
- 13 sites in Belgium, France
- Volunteers
- 320 people
- Sponsor
- Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives
Age-Related Macular Degeneration, Allergies
Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives
To collect, preserve, and/or distribute annotated biospecimens and associated medical data to institutionally approved, investigator-directed biomedical research to discover and develop new treatments, diagnostics, and…
- Conditions
- Age-Related Macular Degeneration, Allergies, Alpha-Gal Syndrome, Alzheimer Disease
- Trial name
- NCT05635266
- Testing
- Specimen sample
- Where
- United States
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Sanguine Biosciences
Inflammatory Bowel Disease (IBD), Ulcerative Colitis
Healthy Approach to Physical and Psychological Problems in Youngsters With IBD (HAPPY-IBD).
The presented study aims to reduce symptoms of depression and anxiety in adolescents with inflammatory bowel disease and increased symptoms of anxiety and depression by using the disease specific CBT program (PASCET-PI)in order…
- Conditions
- Inflammatory Bowel Disease (IBD), Ulcerative Colitis, Crohn's Disease, Anxiety
- Trial name
- HAPPY-IBD (NCT02265588)
- Testing
- Cognitive behavioral therapy
- Where
- Netherlands
- Volunteers
- 70 people
- Sponsor
- Erasmus Medical Center
Crohn Disease, Ulcerative Colitis
Autoimmune Protocol Diet and Inflammatory Bowel Disease
There is limited data to guide the use of dietary change in the management of IBD, and it can prove challenging to implement in the setting of altered anatomy, comorbid conditions, and patient compliance.
- Conditions
- Crohn Disease, Ulcerative Colitis, Inflammatory Bowel Diseases
- Trial name
- NCT03512327
- Testing
- Autoimmune protocol (AIP) diet
- Volunteers
- 15 people
- Sponsor
- Scripps Health
IBD, Inflammatory Bowel Diseases
The Assessment of Infrared Treatment for Crohn's Disease
The goal of this clinical trial is to test the safety and efficacy of far Infra-red (fIR) therapy in Crohn's disease patients. The main questions it aims to answer are: 1.
- Conditions
- IBD, Inflammatory Bowel Diseases, Crohn Disease
- Trial name
- NCT06146816
- Testing
- High level photobiomodulation treatment in the infrared (IR) range., Medium level photobiomodulation treatment in the far infrared (IR) range, Low level photobiomodulation treatment in the far infrared (IR) range
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Shmuel Kivity, MD
Crohn Disease
Mesenteric Sparing for the Prevention of Recurrent Crohn's Disease
The purpose of this study is to determine if taking an increased sampling of mesentery (fatty tissue next to the intestine) and lymph nodes at the time of the subject's ileocolic resection prevents a 4-6 month recurrence of…
- Trial name
- NCT03172143
- Testing
- Mesenteric Sparing Ileocolic Resection, High Ligation Ileocolic Resection
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Mayo Clinic
Crohn's Disease (CD)
An Observational, Multicenter Study to Evaluate the Effectiveness of Guselkumab for the Treatment of Participants With Crohn's Disease After Surgical Resection
The goal of this single arm ,non-interventional, prospective, descriptive study is to evaluate the efficacy of guselkumab treatment in preventing endoscopic recurrence of Crohn's Disease in adult participants who have a…
- Trial name
- POST-CD (NCT07528040)
- Testing
- Guselkumab
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Shanghai 10th People's Hospital
Crohn's Disease
Long-term Safety and Tolerability Study of Adalimumab in Subjects With Crohn's Disease
To evaluate the long-term maintenance of response, safety and tolerability of repeated administration of adalimumab in subjects with Crohn's disease who participated in and successfully completed Protocol M02-404 or Protocol…
- Trial name
- NCT00195715
- Testing
- Adalimumab
- Where
- 111 sites in United States, Australia and 13 more
- Volunteers
- 777 people
- Sponsor
- Abbott
Crohn's Disease
Safety and Efficacy of Natalizumab in the Treatment of Crohn's Disease
The purpose of this study is to determine the safety and efficacy of natalizumab in individuals diagnosed with moderately to severely active Crohn's disease.
- Trial name
- NCT00032799
- Testing
- natalizumab
- Where
- United States
- Volunteers
- 905 people
- Sponsor
- Biogen
Inflammatory Bowel Disease, Crohn's Disease
Low Dose Naltrexone in Symptomatic Inflammatory Bowel Disease
The investigators will be looking at the efficacy of the use of once daily use of low dose naltrexone (4.5mg) in subjects with symptomatic inflammatory bowel disease.
- Conditions
- Inflammatory Bowel Disease, Crohn's Disease, Ulcerative Colitis
- Trial name
- NCT01810185
- Testing
- Low dose naltrexone
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Santa Barbara Cottage Hospital
IBD and Renal Involement, Chronic Kidney Disease
Renal Dysfunction in Patients With Inflammatory Bowel Disease and the General Population (NEPHRO-IBD)
The NEPHRO-IBD study is a multicenter prospective observational study designed to evaluate the prevalence of renal dysfunction and renal complications in adult patients with inflammatory bowel disease (IBD) compared with…
- Conditions
- IBD and Renal Involement, Chronic Kidney Disease, Inflamatory Bowel Disease (Crohn's and Ulcerative Colitis)
- Trial name
- NEPHRO-IBD (NCT07593352)
- Testing
- Prospective assessment of the prevalence of kidney disease and/or renal complications in patients with IBD/the general population based on routine laboratory test and abdominal ultrasound.
- Where
- Poland
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Państwowy Instytut Medyczny Ministerstwa Spraw Wewnętrznych i Administracji
Crohn Disease, Ulcerative Colitis
Impact of Prebiotics in Ulcerative Colitis
The cause of inflammatory bowel disease (IBD) is currently unknown, although partly attributed to interactions among genetic risk polymorphisms, environmental factors, gut microbiome, and host immunity.
- Trial name
- NCT06495658
- Testing
- Prebiotic
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of California, Los Angeles
Inflammatory Bowel Diseases (IBD), Crohn Disease (CD)
NORDTREAT Prospective Study on Inflammatory Bowel Disease
Inflammatory bowel disease (IBD), primarily ulcerative colitis (UC) and Crohn's disease (CD), is a chronic disease entity affecting individuals of all ages, and which may severely impact the lives of the patients and their…
- Conditions
- Inflammatory Bowel Diseases (IBD), Crohn Disease (CD), Ulcerative Colitis (UC)
- Trial name
- NCT05414578
- Where
- 17 sites in Denmark, Iceland and 2 more
- Volunteers
- 366 people
- Sponsor
- University of Southern Denmark
Inflammatory Bowel Disease (Crohn's Disease; Ulcerative Colitis)
Analysis of Barriers and Facilitators to Adapted Physical Activity for Pediatric Patients With Chronic Inflammatory Bowel Diseases
This study aims to identify perceived barriers and facilitators to regular physical activity among children and adolescents with inflammatory bowel disease (IBD) followed in pediatric gastroenterology.
- Trial name
- Feels-Mici (NCT07383844)
- Testing
- IMPACT-III questionnaires, Data collection: CAPAS-Q, semi-structured interview
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Fondation Lenval
Inflammatory Bowel Disease, Crohn's Disease
Levels of the Stat4 Alpha and Stat4 Beta Isoforms in PBMCs From Patients With Crohn's Disease and Ulcerative Colitis
The goal in these studies will be to assess the relative levels of the Stat4 alpha and Stat4 beta isoforms in PBMCs from patients with Crohn's Disease, ulcerative colitis, celiac disease or from control patients.
- Conditions
- Inflammatory Bowel Disease, Crohn's Disease, Ulcerative Colitis
- Trial name
- NCT00586599
- Testing
- measurement of inflammatory markers
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Indiana University