Clinical trials: Crowding, open to volunteers
Triage, Low Acuity Patients
FOllow-up of LOW-acuity Patients After REdirection From a Swiss Emergency Department Using an Electronic TRIage Application
Emergency department (ED) overcrowding is a growing issue, affecting patient safety, healthcare quality, and hospital efficiency.
- Conditions
- Triage, Low Acuity Patients, Health Literacy Level, Non-urgent Emergencies
- Trial name
- FO-LOW-RETRI (NCT06971419)
- Testing
- intervention is the use of aTriage-Based Patient Redirection Using an Electronic Decision Support Toolin the emergency department (ED)
- Where
- Switzerland
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Hôpital Fribourgeois
Macular Degeneration
Learning Study: Improving Vision in Adults With Macular Degeneration
The purpose of this study is to test whether a kind of brain stimulation called anodal transcranial direct current stimulation (a-tDCS) can be combined with perceptual learning to improve the ability of people with age-related…
- Trial name
- NCT04762368
- Testing
- Active anodal tDCS
- Where
- 2 sites in Canada, Hong Kong
- Volunteers
- 30 people
- Sponsor
- University of Waterloo
Crowding, Tooth, Gingival Diseases
Gingival Phenotype and Dental Crowding in Pediatric Patients
The periodontal phenotype influences treatment outcomes across dental specialties, as tissues of different thickness respond differently to chemical, bacterial, and mechanical insults.
- Trial name
- BIOTIPO_PEDO (NCT07205172)
- Testing
- Orthodontic and periodontal analysis
- Where
- Italy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Crowding of Anterior Maxillary Teeth, Orthodontics, Interceptive
Interceptive Maxillary Expansion to Relief Anterior Crowding in the Mixed Dentition
The goal of this clinical trial is to compare if it is better to treat severe anterior crowding in the early mixed dentition then later in the permanent dentition in children with anterior crowding of the upper teeth.
- Conditions
- Crowding of Anterior Maxillary Teeth, Orthodontics, Interceptive, Orthodontics, Corrective, Palatal Expansion Technique
- Trial name
- NCT06187337
- Testing
- Maxillary expansion device
- Where
- 4 sites in Italy, Sweden
- Volunteers
- 60 people
- Sponsor
- Region Örebro County
Crowding of Anterior Mandibular Teeth
Evaluating the Efficacy of Micro-Osteoperforations Technique on the Orthodontic Tooth Movement Acceleration in Moderate Mandibular Anterior Crowding Cases Treated With Clear Aligners
Patients with moderate mandibular anterior crowding will be treated in this study. The efficacy of micro-osteoperforations technique by special drill in accelerating orthodontic tooth movement during clear aligners therapy will…
- Trial name
- NCT05492773
- Testing
- Micro-osteoperforations Technique, Active comparater
- Where
- Syria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hama University
Colorectal Cancer
A Community Population Screening Cohort Study Based on Polygene Methylation Detection for Colorectal Cancer in Yangzhou
This is a cross-sectional cohort study based on community population jointly developed by Northern Jiangsu People's Hospital and Shanghai Kunyuan Biological Technology Co., LTD.
- Trial name
- NCT05336539
- Where
- 2 sites in China
- Volunteers
- 80,000 people, healthy volunteers welcome
- Sponsor
- Singlera Genomics Inc.
Malaligned Teeth, Crowding of Teeth
Effect of Different Adhesive Systems on White Spot Lesions During Fixed Orthodontic Treatment
The primary goal of this study is to compare the number of white spot lesions during fixed appliance therapy between self-etch and one-step bonding systems.
- Trial name
- NCT07753512
- Testing
- Self-etch adhesive, One-Step Adhesive, Conventional Bonding Technique
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Angle Class I Maloclussion, Dental Crowding
Orthodontic Treatment Outcomes of Self Ligating System Compared to Clear Aligner System
This study is a multi-center, prospective, parallel-group randomized controlled trial designed to compare the orthodontic treatment outcomes of a passive self-ligating bracket system (Damon Ultima) versus a clear aligner system.
- Trial name
- NCT07638397
- Testing
- self ligating bracket, Clear aligner
- Where
- Iraq
- Volunteers
- 42 people
- Sponsor
- University of Baghdad
Acute Disease, Sepsis
Acutelines: a Large Data-/Biobank of Acute and Emergency Medicine
Research in acute care faces many challenges, including enrollment challenges, legal limitations in data sharing, limited funding, and lack of singular ownership of the domain of acute care.
- Conditions
- Acute Disease, Sepsis, Pneumonia, Frailty
- Trial name
- Acutelines (NCT04615065)
- Where
- Netherlands
- Volunteers
- 35,000 people
- Sponsor
- University Medical Center Groningen
Malocclusions, Narrow Maxilla
Hyrax Vs. Invisalign Palatal Expander Clinical Study
The purpose of this study is to compare expansion result and the overall experience between the Invisalign Palatal Expander and the Hyrax expander.
- Conditions
- Malocclusions, Narrow Maxilla, Narrow Maxillary Arch, Crowding
- Trial name
- NCT06662279
- Testing
- Removable Rapid Palatal Expander, Banded Palatal Expander
- Where
- 4 sites in United States
- Volunteers
- 36 people
- Sponsor
- Align Technology, Inc.
Triage, Emergency Department Triage
Impact of Point-of-care Lactate Testing as Triage Supplement on Patient Management Using Manchester Triage System
Although the Manchester Triage System (MTS) is widely used and validated internationally, it has some limitations. Its accuracy is moderate, especially for children and the elderly.
- Conditions
- Triage, Emergency Department Triage, Emergency Department Overcrowding, Emergency Medicine
- Trial name
- NCT07123857
- Testing
- re-triage
- Where
- Slovenia
- Volunteers
- 200 people
- Sponsor
- University Medical Centre Maribor
Crowding of Anterior Mandibular Teeth
Efficiency, Efficacy, Periodontal & Occlusal Outcomes for Aligners Versus Fixed Orthodontic Appliances in Crowded Incisor Treatment
The goal of this clinical trial is to compare between fixed labial braces and clear aligners for the straightening of moderately overlapped lower front teeth.
- Trial name
- NCT06731465
- Testing
- Clear aligner therapy, Fixed pre-adjusted edgewise orthodontic appliance
- Where
- United Arab Emirates
- Volunteers
- 40 people
- Sponsor
- University of Sharjah
Effectiveness of the I-arch System
Clinical Performance of the I-arch System During the Initial Stage of Orthodontic Treatment
The goal of this clinical trial is to learn if the I-arch system works to align the moderately misaligned teeth in patients seeking orthodontic treatment.
- Trial name
- NCT07264127
- Testing
- The use of 0.016×0.014 copper nickel titanium arch wire during the alignment stage., Use of 0.014- then 0.016-inch heat-activated nickel titanium arch wire during the alignment stage.
- Where
- Iraq
- Volunteers
- 34 people
- Sponsor
- Tabark H. Omran
Dental Crowding, Gingival Recession
Evaluating the Clinical Efficacy of Collagen Scaffold (Ossix VOLUMAX) With Piezo-Surgical Decortication in Enhancing Orthodontic Treatment Outcomes: A Randomized Controlled Trial
Recent advances in orthodontic treatment have explored various materials to enhance treatment efficacy, particularly focusing on collagen scaffolds.
- Conditions
- Dental Crowding, Gingival Recession, Thin Phenotype
- Trial name
- NCT07097714
- Testing
- Piezocision with ribose cross-linked collagen matrix (Ossix® Volumax), control
- Where
- Russia
- Volunteers
- 70 people
- Sponsor
- NMSI DENTMASTER
Mild-to-Moderate Mandibular Anterior Crowding
Bracketless Orthodontic Treatment (3D-BOT) Versus Conventional Fixed Braces for Mild-to-Moderate Lower Front Tooth Crowding in Adults
This study will compare two fixed orthodontic treatments for mild-to-moderate crowding of the lower front teeth in adults. Participants will be randomly assigned to three-dimensional bracketless orthodontic treatment (3D-BOT)…
- Trial name
- 3D-BOT-RCT (NCT07897864)
- Testing
- Conventional Labial Fixed Orthodontic Appliance, 3D-BOT Using E-WIRE Archwires
- Where
- Syria
- Volunteers
- 30 people
- Sponsor
- University of Aleppo
Class I Malocclusion, Crowded Teeth
The Predictability of Directly Printed Versus Thermoformed Clear Aligners
The study is randomized controlled trial ...The null hypothesis suggests that there is no significant difference between actual and predicted dental movement in patients treated using direct printed aligners produced with Graphy™…
- Conditions
- Class I Malocclusion, Crowded Teeth, Spacing of Anterior Teeth, Rotation
- Trial name
- NCT07350343
- Testing
- Direct-printed aligner (Graphy), Thermoformed aligner
- Where
- Iraq
- Volunteers
- 36 people
- Sponsor
- University of Baghdad
Cancer
A Crowd Sourcing Platform for Patients With Cancer
All4Cure aims to accelerate learning about cancer by sharing medical information and research results from cancer patients with fellow cancer patients, oncologists, and scientists on the All4Cure website with the hope that…
- Trial name
- NCT03530826
- Testing
- No intervention
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- All4Cure
Dental Crowding, Dental Occlusion, Traumatic
Exploration of the Utility of Dental-dedicated MRI for Dentistry
This description observational research is comparative in design, that is comparing existing standard clinical dental images, not obtained in this study, to test (i.e., ddMRI) images.
- Conditions
- Dental Crowding, Dental Occlusion, Traumatic, Endodontic Disease, Orthodontic Treatment
- Trial name
- NCT06948162
- Testing
- dental-dedicated MRI (ddMRI)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Length of Stay, Emergency Department Crowding
Digital Anticipatory Protocols at Triage to Improve ED Flow.
This study aims to evaluate a pre-post intervention adding an early management decision at the end of the triage process to improve patient throughput.
- Conditions
- Length of Stay, Emergency Department Crowding, Emergency Department Patient, Emergency Department Triage
- Trial name
- NCT07726108
- Testing
- Digital Anticipatory Protocols at Triage
- Where
- Switzerland
- Volunteers
- 15,500 people, healthy volunteers welcome
- Sponsor
- Hôpital Fribourgeois
Tooth Crowding
Effect of Force Magnitude on Canine Retraction and Gingival Crevicular Fluid Proteome
This study aims to examine the effect of force levels in orthodontic treatment during canine retraction. Force levels refer to the pressure applied by the orthodontic devices to move teeth.
- Trial name
- NCT06668194
- Testing
- Light Force (150g Niti Coil), Heavy Force (400 g Niti coil)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- UConn Health