Clinical trials: Cruciate Ligament Injury
Anterior Cruciate Ligament Injuries, Opioid Use
Safe Options for ACL Recovery
The purpose of the proposed work is to test a brief opioid exposure reduction program (ACL-OERP) designed to improve health literacy about opioid use following surgeries.
- Trial name
- SOAR (NCT04225468)
- Testing
- ACL Opioid Exposure Reduction Program
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Karen Derefinko, PhD
Anterior Cruciate Ligament Rupture
Are Clinical Outcomes Unchanged by ALL Fixation at 0° or 30° of Knee Flexion in Combined ACL-ALL Reconstruction? Despite Numerous Technical Descriptions of Anterolateral Procedures, There is Limited Knowledge Regarding the Effect of Knee Flexion Angle During Graft Fixation.
This study evaluates whether the knee flexion angle used during fixation of the anterolateral ligament (ALL) affects clinical outcomes in patients undergoing combined anterior cruciate ligament (ACL) and ALL reconstruction.
- Trial name
- ACL ALL (NCT07451743)
- Testing
- anterolateral ligament reconstruction
- Volunteers
- 100 people
- Sponsor
- ASL Lecce
Anterior Cruciate Ligament Injuries
The Impact of Germanium-Embedded Knee Brace on Patient Recovery After ACL Reconstruction
Anti-inflammatory brace technology has demonstrated superior clinical outcomes in the management of knee osteoarthritis and accelerate recovery time for Major League Soccer players.
- Trial name
- NCT05068297
- Testing
- Incrediwear Germanium-Embedded Knee Brace following ACL reconstruction, Replica Knee Brace
- Volunteers
- 100 people
- Sponsor
- Total Sports Medicine & Orthopedics
Anterior Cruciate Ligament Tear, Ankle Sprains
Effect of ACL Reconstruction in Biomechanical Properties of Ankle Joint Complex
BACKGROUND: Anterior cruciate ligament (ACL) is an important ligamentous structure in the knee joint which contributes in maintaining stability.
- Trial name
- NCT06631690
- Testing
- Isokinetic and functional balance tests
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Anterior Cruciate Ligament (ACL)
Preoperative Rehabilitation for Patient With an ACL Injury
Muscle qualities are critical for the recovery after an anterior cruciate ligament (ACL) injury. Before ACL reconstruction (ALCR), resistance training aims to maintain patient strength and volume in order to optimize recovery.
- Trial name
- K-POP (NCT07411625)
- Testing
- Resistance training, Traditional exercises
- Where
- France
- Volunteers
- 84 people
- Sponsor
- Nantes University Hospital
Ligament Knee Injury, Anterior Cruciate Ligament Rupture
Optimized Rehabilitation After Anterior Cruciate Ligament Before Returning to Sport
Following reconstruction of the anterior cruciate ligament (ACL), a standardized rehabilitation protocol is carried out by a physiotherapist.
- Trial name
- ORACL-Run (NCT05323474)
- Testing
- Usual rehabilitation, Rehabilitation optimized
- Where
- 8 sites in France, Switzerland
- Volunteers
- 432 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Knee Injuries
Clinical Outcome of Posterior Cruciate Ligament (PCL) Posterolateral Reconstruction
The purpose of this investigation is to determine the clinical outcome of surgical reconstruction of complete ruptures to the posterior cruciate ligament (PCL) and posterolateral structures of the knee joint.
- Trial name
- NCT00991588
- Testing
- PCL, posterolateral reconstruction
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Sue Barber-Westin
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Reconstruction of the Anterior Cruciate Ligament of the Knee Joint, by the Method of Stabilization of the Screw With a Bioabsorbable Method, With or Without the Use of Autogenous Spongiform Bone Grafts.
Clinical and comparative evaluation of the results of autograft healing of the tendon of the semitendinus muscle in the tibial canal, after reconstruction of the anterior cruciate ligament of the knee joint, by the method of…
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear, Knee Injuries
- Trial name
- NCT05328544
- Testing
- ACL reconstruction of the knee joint by arthroscopic technique, with the tibial fixation method using a bioabsorbable screw (Arthrex) with the use of autogenous cancellous bone grafts, ACL reconstruction of the knee joint by arthroscopic technique, with the tibial fixation method using a bioabsorbable screw (Arthrex) without the use of autogenous cancellous bone grafts
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- eMKa MED Medical Center
Rupture of Anterior Cruciate Ligament, Osteoarthritis
French Prospective Anterior Cruciate Ligament Reconstruction Cohort Study (FAST)
In this study we will examine patients who have undergone anterior cruciate and/or posterior cruciate ligament and/or multi ligaments reconstruction to determine the rate of re-injury, contralateral tear and functional outcomes…
- Trial name
- FAST (NCT02511158)
- Testing
- Ligament of the knee reconstruction
- Where
- France
- Volunteers
- 7,000 people
- Sponsor
- Fonds de Dotation pour la Recherche Clinique en Orthopédie et Pathologie du Sport
Anterior Cruciate Ligament Rupture
Effect of Preoperative Exercise Habits on Knee Function and Recurrence Rate After Anterior Cruciate Ligament Reconstruction
The aim of this study is to compare the knee function between patients with and without preoperative exercise habits at 1, 2 and 5 years after ACL surgery, and further analyze the effect of maintaining exercise habits on knee…
- Trial name
- NCT06608394
- Testing
- no intervention
- Where
- China
- Volunteers
- 361 people
- Sponsor
- Peking University Third Hospital
Anterior Cruciate Ligament Rupture, Quadriceps Muscle Atrophy
Blood Flow Restriction After Anterior Cruciate Ligament Reconstruction (ACLR)
Muscle strength and muscle volume decrease rapidly with the immobilization process after sports-related injury and surgery. Depending on the decrease in muscle strength and muscle volume, functional performance also deteriorates…
- Trial name
- ACLR (NCT05500872)
- Testing
- Cross-education and blood flow restriction training, Cross-education
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Hacettepe University
Anterior Cruciate Ligament (ACL) Tear, Anterior Cruciate Ligament (ACL)
Prospective Cohort Study of Villarreal CF Youth Players
Anterior cruciate ligament (ACL) injuries represent a highly relevant issue in both grassroots and professional sports, with a particularly high incidence in young and female populations.
- Trial name
- VILLAREALFC (NCT07653633)
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Cardenal Herrera University
Vibration Therapy, Anterior Cruciate Ligament Injuries
Investigation of the Effects of Vibration Therapy on Pain, Functionality, and Proprioception After ACL Injury
Over the past decade, vibration therapy has gained popularity. This treatment involves the transmission of vibration either through whole-body vibration (WBV) platforms or by applying local vibration (LV) directly to the muscles…
- Trial name
- NCT06185231
- Testing
- Percussion Massage Group, Conventional Group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul Medipol University Hospital
ACL Injury
Association Between Neuromuscular Parameters and Functional Assessment After ACL Reconstruction
The anterior cruciate ligament (ACL) injury is common in athletes aged 18 to 35. ACL reconstruction (ACLR) aims to restore knee stability in the process of returning to sports.
- Trial name
- KASTLAB (NCT06524869)
- Testing
- Isokinetic neuromuscular assessment
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Caen
Anterior Cruciate Ligament Rupture
BioCleanse Tibialis Tendon Anterior Cruciate Ligament (ACL) Study
To compare the outcome of Anterior Cruciate Ligament (ACL) reconstruction performed using the tibialis allograft to historical outcomes of ACL reconstruction patients and to establish if any correlation exists between the age of…
- Trial name
- NCT00975845
- Testing
- BioCleanse Tibialis tendon
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- RTI Surgical
Anterior Cruciate Ligament Injuries, Athletic Injuries
Comparison of Autologous Quadriceps and Hamstring Tendon Grafts in Anterior Cruciate Ligament Reconstruction
With the recent technological advancements, the use of the quadriceps tendon with an all-inside technique has come to the forefront, and large-scale research has focused especially on quadriceps tendon grafts.
- Conditions
- Anterior Cruciate Ligament Injuries, Athletic Injuries, Tendon Graft; Complications
- Trial name
- NCT06617559
- Testing
- Anterior Cruciate Ligament Reconstruction with Quadriceps Autograft, Anterior Cruciate Ligament Reconstruction with Hamstring Autograft
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Muzaffer Agir
Anterior Cruciate Ligament (ACL) Tear, Arthroscopic Anterior Cruciate Ligament Reconstruction
Intraoperative Periarticular Injection in Arthroscopic Anterior Cruciate Ligament Reconstruction Surgery
In this prospective, assessor-blinded, single-surgeon clinical trial, the goal was to validate the efficacy of PAI in aACLR surgery with a reduced opioid dose, while achieving similar pain relief with few adverse events.
- Trial name
- PAI in ACLR (NCT06630520)
- Testing
- Periarticular injection
- Where
- Taiwan
- Volunteers
- 288 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Anterior Cruciate Ligament Injury
Effects of Elastic Therapeutic Tape on Biomechanical Changes of Knee Joint During Drop Vertical Jump in ACL Injuries
The purpose of this study to investigate joint angle and joint moment in flexion-extension, adduction-abduction and internal -external rotation of elastic therapeutic tape and elastic therapeutic tape are effective in…
- Trial name
- NCT02271061
- Testing
- Kinesio tape, Control tape
- Volunteers
- 8 people
- Sponsor
- Mahidol University