Clinical trials: Cruciate Ligament Injury
Intraoperative Musculoskeletal Injury
Intraoperative Laxity Assessment of ACL Reconstruction, ACL Revision and MAT
Intraoperative knee laxity evaluation of patiente undergoing ACL reconstruction, ACL revision, MAT
- Trial name
- INTRA_KIN (NCT03441165)
- Testing
- ligament reconstruction and meniscus transplantation
- Where
- Italy
- Volunteers
- 1,500 people
- Sponsor
- Istituto Ortopedico Rizzoli
ACL Injury, Knee Osteoarthritis
The Efficiency and Safety of PRP Treatment After Anterior Cruciate Ligament Reconstruction.
The anterior cruciate ligament (ACL) is the main stabilizer of the knee joint, as it controls anteroposterior and rotatory knee laxity.
- Conditions
- ACL Injury, Knee Osteoarthritis, Knee Injuries
- Trial name
- NCT06442319
- Testing
- Platelet-rich plasma
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Nicolaus Copernicus University in Toruń, Collegium Medicum in Bydgoszcz
ACL Anterior Cruciate Ligament Injury, Outcome
Outcome and Tunnel Widening After ACL Reconstruction: Comparison of Aperture and Cortical Fixation
Background: Failure of graft incorporation and tunnel widening (TW) after anterior cruciate ligament (ACL) reconstruction has been frequently reported in the literature. The etiology of TW is still not fully understood.
- Trial name
- NCT01755819
- Testing
- Biocomposite interference screw, Extracortical ACL Tightrope fixation
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University Innsbruck
ACL Injury
Dietary Protein Intake and Rehabilitation From Anterior Cruciate Ligament Surgery
Protein supplementation may promote increases in strength and hypertrophy in the context of resistance training (RT) and reduce markers of inflammation, while sufficient levels of protein are necessary for healing certain wounds…
- Trial name
- NCT03614351
- Testing
- Protein (PROT), Control (CONT)
- Sponsor
- Wake Forest University Health Sciences
Anterior Cruciate Ligament Rupture
Allogeneic Bone-patellar Tendon-bone Transplantation
Objective To investigate the mid-term clinical effect of bone-patellar tendon-bone (BPTB) graft double-bundle reconstruction of the anterior cruciate ligament (ACL) of the knee joint under arthroscope.
- Trial name
- NCT04951531
- Testing
- BPTB double-bundle allograft, BPTB single-bundle allograft group, BPTB single-bundle autograft group
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Peking University Third Hospital
ACL Injury
Clinical Outcomes of ACL Reconstruction Augmented by an Injectable Osteoconductive/Osteoinductive Compound
The goal of this study is to determine whether the use of injectable osteoinductive/osteoconductive compounds (OOC) during Anterior Cruciate Ligament (ACL) reconstructive surgery, combined with an accelerated rehabilitation…
- Trial name
- NCT04993339
- Testing
- OOC
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Miami
Anterior Cruciate Ligament Tear
Prospective Femoral Versus Femoral and Sciatic Nerve Block for Anterior Cruciate Ligament (ACL) Reconstruction
The investigators propose that a preoperative femoral and sciatic blocks vs a femoral block only, prior to ambulatory anterior cruciate ligament (ACL) reconstruction will lead to a decrease in opiate consumption, pain scores, and…
- Trial name
- NCT01447277
- Testing
- Sciatic Block, Femoral Block only
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of California, San Francisco
Knee Injuries
Efficacy and Safety of OMS103HP in Patients Undergoing Autograft Anterior Cruciate Ligament (ACL) Reconstruction
The anterior cruciate ligament (ACL) is an important stabilizer of the knee. Orthopedic surgeons replace the torn ligament during ACL reconstruction surgery.
- Trial name
- NCT00226772
- Testing
- OMS103HP, Vehicle
- Where
- 18 sites in United States, Canada
- Volunteers
- 326 people
- Sponsor
- Omeros Corporation
Acute Ruptures of the Anterior Cruciate Ligament
L-C Ligament Versus Hamstring Autograft for Primary ACL Reconstruction
The purpose of this study is to compare safety and efficacy outcomes of the L-C Ligament versus Hamstring Autograft for treatment of acute rupture of the ACL.
- Trial name
- NCT02183727
- Testing
- L-C Ligament, Hamstring Autograft
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Soft Tissue Regeneration, Inc.
Anterior Cruciate Ligament Tear
Regenexx™ SD Versus Exercise Therapy for ACL Tears
The primary objective of this study is to compare the improvement in subject-reported clinical outcomes for Regenexx SD vs. Exercise Therapy treatment of partial and complete, non-retracted knee ACL ligament tears, from baseline…
- Trial name
- NCT01850758
- Testing
- Regenexx SD, Exercise Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Regenexx, LLC
Anterior Cruciate Ligament Injuries, Muscle Weakness
Changes in the Force-velocity Relationship of Knee Muscles After ACL Reconstruction
Anterior cruciate ligament (ACL) tear is a frequent and devastating injury in sport, especially in pivoting-contact disciplines.
- Trial name
- FoVeA (NCT05712109)
- Testing
- Follow-up after Anterior cruciate ligament reconstruction
- Where
- France
- Volunteers
- 103 people
- Sponsor
- University Hospital, Caen
Anterior Cruciate Ligament Rupture, Acute Pain
Femoral Triangle + IPACK Blocks for ACL Reconstruction Analgesia
An adequate balance between analgesia and motor function is an essential requirement to facilitate functional recovery and early discharge after anterior cruciate ligament (ACL) reconstruction surgery. Proximal nerve blocks (i.e.
- Conditions
- Anterior Cruciate Ligament Rupture, Acute Pain, Pain, Postoperative, Knee Injuries
- Trial name
- NCT05068063
- Testing
- Bupivacaine Injection, normal Saline
- Where
- 2 sites in Chile
- Volunteers
- 48 people
- Sponsor
- University of Chile
Anterior Cruciate Ligament Rupture
"Online Surveys" in Perioperative Knee Anterior Cruciate Ligament (ACL) Reconstruction
To monitor the quality of health care systems, patient-reported outcome measures (PROMs) should be collected and analyzed before and after medical interventions.
- Trial name
- ORTHENSE (NCT05423314)
- Testing
- knee brace cold therapy
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Toulouse
Anterior Cruciate Ligament Injuries
Effects of Continuous Passive Movements vs Intermittent Compression in Patients With Post ACL Reconstruction Surgery
ACL Reconstruction Surgery remains a prevalent and debilitating condition, despite invasive and non-invasive approaches aimed at reducing pain and improving function.
- Trial name
- NCT06997679
- Testing
- Patients receiving CPM, Patients receiving intermittent compression
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Superior University
Meniscus Injury, Meniscus Tear
Assessment of Quadriceps Femoris Muscle Function in Patients After Arthroscopic Knee Surgery in Outpatient Rehabilitation
The goal of this clinical trial is to learn if a high intensity magnetic field is an effective way to treat quadriceps muscle atrophy after knee arthroscopic surgery in adult patients.
- Conditions
- Meniscus Injury, Meniscus Tear, Arthroscopic Knee Surgeries, ACL Injuries
- Trial name
- NCT06870825
- Testing
- High-intensity Magnetic Field Muscle Stimulation, Transcutaneous Neuromuscular Electrical Stimulation
- Where
- Lithuania
- Volunteers
- 150 people
- Sponsor
- Lithuanian University of Health Sciences
Anterior Cruciate Ligament Injuries
Prolonged Preoperative Rehabilitation in ACL Rupture.
Rupture of the anterior cruciate ligament is a serious and common injury. In young athletes, surgical reconstruction of the anterior cruciate ligament by autograft with hamstrings or patellar ligament is widely used.
- Trial name
- ISO-LCA-PREOP (NCT04888052)
- Testing
- Acute ACL injury
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Lille
ACL Injury, Hemodynamics
A Paradigm Shift in Musculoskeletal Rehabilitation Assessment After ACL Reconstruction Using Near-Infrared Spectroscopy
This study aims to establish and compare muscle haemodynamic response patterns in physically active subjects with anterior cruciate ligament (ACL) reconstruction, at different time points after surgery, against healthy controls…
- Conditions
- ACL Injury, Hemodynamics, Oxygen Consumption Based Assessment of Hemodynamics, Exercise
- Trial name
- HemoNIRS-LCA (NCT06621355)
- Testing
- Incremental Interval Test on a Cycle Ergometer
- Where
- Spain
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Universitat de Lleida
Patellofemoral Pain Syndrome
Dosage-dependence of Graded Exercise Therapy in Patients With Patellofemoral Pain Syndrome.
With this study two different therapeutic exercise regimens will be compared in patients with anterior knee pain (patellofemoral pain syndrome, PFPS).
- Trial name
- NCT01290705
- Testing
- High exercise therapy, Low exercise therapy
- Volunteers
- 40 people
- Sponsor
- Norwegian University of Science and Technology
Injury of Anterior Cruciate Ligament
Sport Cord Test Following ACL Reconstruction
The primary purpose of this study is to determine the interrater reliability and validity of the Sportcord Test as a measure of physical performance following anterior cruciate ligament (ACL) reconstruction.
- Trial name
- NCT01937403
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- The Hawkins Foundation
Anterior Cruciate Ligament (ACL) Reconstruction, Anterior Cruciate Ligament Injury
Comparison of Bone-patellar Tendon-bone and Patellar Tendon-bone Grafts in ACL Reconstruction
The purpose of this randomized study is to compare donor site morbidity and clinical and functional outcomes of both surgery techniques (bone-patellar tendon-bone (BPTB) graft versus bone-patellar tendon without patellar bone…
- Trial name
- NCT07475351
- Testing
- Bone-Patellar tendon-Bone, Patellar tendon-Bone
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- Universidad de Granada