Clinical trials: Crush Injury
Chronic Ulcer, Venous Ulcer
Efficacy of PICO Single-use System in Chronic Ulcers
A clinical trial will be carried out comparing the efficacy of PICO system based on negative pressure therapy (NPT) in adults with chronic ulcers compared to conventional treatments.
- Conditions
- Chronic Ulcer, Venous Ulcer, Diabetic Foot Ulcer, Pressure Injury
- Trial name
- NCT05877378
- Testing
- Single-use negative pressure therapy (PICO)
- Where
- Spain
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Pressure Ulcer, Nursing Education
Development and Effectiveness Verification of an AI Application for Pressure Injury Nursing Based on Clinical Judgment Model
This clinical trial aims to develop a pressure ulcer nursing AI mobile application based on a clinical judgment model and verify its effectiveness among clinical nurses.
- Trial name
- NCT07132320
- Testing
- Pressure Ulcer Nursing AI Application Training, Traditional Pressure Ulcer Nursing Education
- Where
- South Korea
- Volunteers
- 95 people
- Sponsor
- Yonsei University
Pain, Obesity, Childhood
Sumamos Excelencia Project: Implementation of Best Practices in Clinical Practice (Thrid Edition)
There is a gap between research and clinical practice, leading to variability in decision-making. Multifaceted implementation strategies are for improving implementation of best practices.
- Conditions
- Pain, Obesity, Childhood, Breast Feeding, Incontinence, Urinary
- Trial name
- SE24 (NCT06522529)
- Testing
- Multifaceted implementation strategy
- Where
- Spain
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Instituto de Salud Carlos III
Pressure Ulcer, Predictive Models
Prediction Models for Risk Score and Prognosis of Intraoperatively Acquired Pressure Injury in Surgical Patients
The study aims to effectively identify the risk of intraoperative acquired pressure injuries (IAPI) in surgical patients through a prospective multicenter approach.
- Conditions
- Pressure Ulcer, Predictive Models, Surgical Patient, Clinical Outcome
- Trial name
- NCT06166641
- Testing
- Surgical procedure at operating room
- Where
- China
- Volunteers
- 5,658 people
- Sponsor
- Affiliated Hospital of Guangdong Medical University
Pressure Incidence Prevention
Pressure Injury Prevention in the ICU With Multi-Layer Foam Dressings
A Multi-Centre, Open, Non-controlled, Clinical Investigation to Evaluate the User Friendliness and Wear Time of Multi-layer Foam Dressings With Safetac® for Pressure Injury Prevention in the Intensive Care Unit
- Trial name
- PUP16_01 (NCT02962882)
- Testing
- Mepilex Border
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Molnlycke Health Care AB
Spinal Cord Injuries
Evaluate the Incidence of Sacral and Heel Pressure Ulcers During Acute Care After SCI
This study evaluates the effect of the application of a five-layer foam dressing on the sacrum as well as a boot applied on the heels as preventive measures in the development of pressure ulcers in patients hospitalized with…
- Trial name
- NCT04165395
- Testing
- Five-layer foam dressing, Heelmedix boot
- Where
- Canada
- Volunteers
- 165 people
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Full-thickness Skin Defects, Degloving Injuries
RECELL® System Combined With Meshed Autograft for Reduction of Donor Skin Harvesting in Soft Tissue Reconstruction
A prospective randomized within-subject controlled study to compare the clinical performance of conventional autografting with and without the RECELL system on acute non-burn full-thickness skin defects.
- Conditions
- Full-thickness Skin Defects, Degloving Injuries, Crush Injuries, Laceration of Skin
- Trial name
- NCT04091672
- Testing
- Control Intervention (Conventional Autograft), Investigational Intervention (RECELL + more widely meshed autograft)
- Where
- 18 sites in United States
- Volunteers
- 65 people
- Sponsor
- Avita Medical
Pressure Ulcer Prevention
Evaluation of the Efficacy and Safety of Palmitoleic Acid Oil Composition in Preventing Pressure Injuries
To evaluate the efficacy and safety of a topical palmitoleic acid (POA) oil composition in preventing PIs and reversing Stage I damage using an integrated physiological monitoring approach.
- Trial name
- NCT07547254
- Testing
- Topical POA Oil Composition Application for Pressure Injury Prevention
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Ruijin Hospital
Rapid Sequence Induction
Rapid Sequence Induction Czech Republic: Survey
Rapid sequence induction (RSI) is a common part of routine anesthesiology practice.However several steps of RSI are not based on evidence based data (EBM) and are considered controversial.
- Trial name
- RSICZ (NCT02985970)
- Testing
- questionnaire
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Brno University Hospital
Pressure Injuries, Medical Device Related Pressure Ulcer (MDRPU)
Effect of Central Venous Catheter Dressing Types on Device-Related Pressure Injuries
The purpose of this clinical trial is to evaluate the effect of different central venous catheter dressing methods on the development of medical device-related pressure injuries in participants treated in the intensive care unit.
- Trial name
- CVC PROTECT (NCT07437040)
- Testing
- Gauze Dressing, Chlorhexidine Gluconate Transparent Dressing
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Pressure Ulcer, Pressure Injury
Efficacy of the Dabir Surfaces Micropressure Overlay for Decubitus Ulcer Prevention During Cardiac Surgery
This is a systematic random sampling study of the effects of the Dabir Micropressure Overlay on perioperative pressure injuries during cardiac surgery.
- Trial name
- NCT03884634
- Testing
- Dabir Micropressure Overlay
- Where
- United States
- Volunteers
- 6,627 people
- Sponsor
- The Cleveland Clinic
Pressure Injuries, Wound Care
Effect of Two Different Solutions on Wound Healing in Pressure Injury
Pressure injuries are a condition that reduces patients' quality of life, increases hospitalization time and healthcare costs. When accompanied by infection and complications, mortality increases.
- Conditions
- Pressure Injuries, Wound Care, Wound Cleansing
- Trial name
- NCT06718777
- Testing
- 0.1% polyhexanide Care, 0.9 % NaCl Care
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Mensure Turan
Pressure Injury, Pressure Ulcer
An RCT on Support Surfaces for Pressure Ulcer Prevention
Pressure injuries are a serious health care problem and affect millions of people. Most pressure injuries are avoidable with the application of best practices and with the use of appropriate technology.
- Trial name
- NCT03351049
- Testing
- LAL, Non-LAL
- Where
- United States
- Volunteers
- 457 people
- Sponsor
- David Brienza
Crush Syndrome, Rhabdomyolysis
Inflammation Indıces and Mortality in Adult Crush Syndrome
This single-center, retrospective observational cohort study evaluated the prognostic value of complete blood count-derived inflammatory indices - the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR)…
- Conditions
- Crush Syndrome, Rhabdomyolysis, Systemic Inflammatory Response, Critical Illness
- Trial name
- NCT07433127
- Where
- Turkey (Türkiye)
- Volunteers
- 325 people
- Sponsor
- Ataturk University
Pressure Injuries, Pressure Ulcer Prevention
Gamified Learning for Pressure Injury Prevention
The goal of this Randomized Controlled Trial is to define the effect of gamified teaching methods for pressure injury prevention in intensive care nurses.
- Trial name
- NCT07028892
- Testing
- A gamified mobile learning, Booklet training
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mehmet Akif Ersoy University
Chronic Ulcer of Leg or Foot, Pressure Injury
A Prospective, Multi Centre, Interventional, Non-comparator, Open Label Study to Demonstrate the Efficacy, Safety, and Performance of ConvaFoam™ Dressings in the Management of Indicated Chronic Wound Types.
A prospective, multi centre, interventional, non-comparator, open label study to demonstrate the efficacy, safety, and performance of ConvaFoam™ dressings in the management of indicated chronic wound types.
- Trial name
- MORGEN (NCT05632250)
- Testing
- ConvaFoam
- Where
- 5 sites in United States
- Volunteers
- 95 people
- Sponsor
- ConvaTec Inc.
Pressure Injury, Pressure Injury Prevention
The Effect of a Color-Coded System on Pressure Injury Prevention in the Intensive Care Unit
This study is designed as a randomized controlled trial to examine the effect of using a color-coded classification system that identifies the risks of pressure injuries in the intensive care unit on the development of pressure…
- Conditions
- Pressure Injury, Pressure Injury Prevention, Risk Assessment, Nursing Care
- Trial name
- ICU PI Colors (NCT07470918)
- Testing
- Color-Coded Pressure Injury Risk Assessment Group
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Pressure Injuries, Pressure Injury
Using Music During Wound Care Among Seniors With Pressure Injuries
Pressure injuries (also known as pressure wounds or bed sores) are increasingly common among older adults living in care homes. These wounds often require regular dressing changes, which can be uncomfortable for some.
- Conditions
- Pressure Injuries, Pressure Injury, Pressure Ulcer (PU)
- Trial name
- NCT07456618
- Testing
- Music listening
- Where
- 11 sites in Canada
- Volunteers
- 50 people
- Sponsor
- McMaster University
Respiratory Insufficiency, Pressure Injury
Effectiveness of Platform-Based Lateralization Therapy in Reducing Interface Pressure Between The Patient And The Support Surface
Pressure injury (PI) is characterized as damage to the skin and/or underlying tissues resulting from sustained pressure or a combination of pressure and shear forces between the patient and the support surface.
- Conditions
- Respiratory Insufficiency, Pressure Injury, Intensive Care Medicine, ARDS
- Trial name
- PREVENT-ICU (NCT06819943)
- Testing
- Automated Lateral Rotation Therapy
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- University of Sao Paulo General Hospital
Pressure Injury
Telemedicine Wounds
This study aims to explore the effectiveness of the flipped education model applied to distance digital learning in enhancing the pressure injury staging interpretation skills of long-term care nursing staff.
- Trial name
- Staging (NCT06827925)
- Testing
- Distance Digital Learning
- Where
- Taiwan
- Volunteers
- 112 people
- Sponsor
- Asia University