Clinical trials: Cryopreservation
Elective Egg Freezing, Oocyte Cryopreservation
Decision Aid for Elective Egg Freezing
The goal of this clinical trial is to evaluate whether a culturally tailored decision aid can improve decision-making and clinical outcomes for Taiwanese women considering elective egg freezing.
- Conditions
- Elective Egg Freezing, Oocyte Cryopreservation, Decision Aid, Egg Freezing
- Trial name
- DAEEF (NCT07543445)
- Testing
- elective egg freezing decision aid
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Oncological Disease, Fertility Preservation
Ovarian Tissue Cryopreservation Combined With Oocyte Cryopreservation Versus Oocyte Cryopreservation Alone
Fertility preservation is a crucial aspect of care for oncological patients undergoing gonadotoxic treatments such as chemotherapy, radiotherapy, or surgery, which can significantly reduce ovarian reserve and cause infertility or…
- Trial name
- NCT07546123
- Where
- Italy
- Volunteers
- 127 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Liver Transplantation
Post-Static Cold Storage Hypothermic Oxygenated Perfusion in Bergamo Liver Transplant Program
In light of the widespread organ shortage, dynamic preservation by means of Machine Perfusion (MP) has been proposed as a strategy to increase the pool of suitable grafts for liver transplantation.
- Trial name
- NCT03098043
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Papa Giovanni XXIII Hospital
Degenerative Disc Disease
Trinity Evolution in Posterior or Transforaminal Lumbar Interbody Fusion (PLIF/TLIF)
The purpose of this study is to utilize Trinity Evolution in conjunction with an interbody spacer and supplemental posterior fixation of the surgeon's choice and to follow the patients to measure the clinical outcomes and rate of…
- Trial name
- TLF (NCT00965380)
- Where
- 15 sites in United States
- Volunteers
- 207 people
- Sponsor
- Orthofix Inc.
Infertility, Egg Freezing
Egg Freezing Pilot Study
University Reproductive Associates is conducting a pilot study to study the technique of egg freezing. Your participation in this study will provide us with important information to allow us to offer this technology for women…
- Trial name
- NCT00839839
- Testing
- Oocyte Vitrification
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University Reproductive Associates
Cancer, Cancer-Related Condition
Testicular Tissue Cryopreservation in Children
This protocol is being designed to offer testicular tissue cryopreservation to male pediatric patients (0-17 years of age) with fertility threatening medical diagnoses or facing surgery, chemotherapy or radiation therapy that may…
- Conditions
- Cancer, Cancer-Related Condition, Infertility
- Trial name
- NCT02872532
- Testing
- Testicular tissue cryopreservation
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Mayo Clinic
Leukemia, Lymphoma
Comparing Fresh Random Platelets and Autologous Cryopreserved Thrombosol Treated Autologous Platelets
Objectives: Determine the corrected count increment of autologous transfused platelets that had been stored by cryopreservation with ThromboSol.
- Trial name
- NCT00074763
- Testing
- Platelet Transfusion
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Lung Cancer, Tracheal Neoplasm
Airway and/or Pulmonary Vessels Transplantation
First study (BRONC-ART) The purpose of this prospective study is to evaluate the 90-day morbidity and mortality rates of bronchial transplantation using cryopreserved aortic allograft in proximal lung cancer surgery.
- Conditions
- Lung Cancer, Tracheal Neoplasm, Tracheal Stenosis
- Trial name
- TRACHBRONCAR (NCT01331863)
- Testing
- Airway and/or pulmonary Vessels Transplantation
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Corneal Edema
Study of Cryopreserved AURN001 in Subjects With Corneal Edema Secondary to Corneal Endothelial Dysfunction
The purpose of this study is to assess the safety and efficacy of cryopreserved AURN001 in patients with corneal edema secondary to endothelial dysfunction.
- Trial name
- NCT06630169
- Testing
- Cryopreserved AURN001
- Where
- El Salvador
- Volunteers
- 25 people
- Sponsor
- Aurion Biotech
Infertility, Subfertility
Comparison of Transfers of Fresh and Thawed Embryos in Patients With Prior Failed Embryo Transfer Cycles
This study seeks to determine if patients with a history of failed fresh embryo transfer(s) will have increased success rates with embryo cryopreservation and subsequent thawed embryo transfer when compared to fresh embryo…
- Trial name
- NCT00736177
- Testing
- Embryo cryopreservation, Fresh embryo transfer
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Fertility Center of Las Vegas
Septic Shock, Sepsis
Cellular Immunotherapy for Septic Shock
Septic shock is associated with substantial burden in terms of both mortality and morbidity for survivors of this illness. Pre-clinical sepsis studies suggest that mesenchymal stem (stromal) cells may modulate inflammation…
- Conditions
- Septic Shock, Sepsis, Pathologic Processes, Shock
- Trial name
- CISS2 (NCT03369275)
- Testing
- Allogeneic Bone Marrow-Derived Human Mesenchymal Stem Cells
- Volunteers
- 114 people
- Sponsor
- Ottawa Hospital Research Institute
Cancer, Autoimmune Disorders
Testicular Tissue Cryopreservation for Fertility Preservation
Testicular tissue cryopreservation is an experimental procedure where a young boy's testicular tissue is retrieved and frozen. This technique is reserved for young male patients who are not yet producing mature sperm, with the…
- Trial name
- NCT02972801
- Testing
- Testicular biopsy
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- University of Pittsburgh
Infertility
Impact of Embryo Cryopreservation on Birth Weight
Birth weight (BW) is higher after frozen embryo transfer (FET) than after fresh embryo replacement. No study has compared the BW of siblings conceived using the same oocyte/embryo cohort.
- Trial name
- NCT03989843
- Where
- France
- Volunteers
- 183 people
- Sponsor
- University Hospital, Montpellier
Aging, Epigenetic Aging
Human Sperm Cryopreservation as an Alternative to the Decline of Sperm Quality With Aging
This observational study will evaluate whether sperm cryopreservation can help preserve sperm quality and molecular characteristics that may be affected by increasing paternal age.
- Conditions
- Aging, Epigenetic Aging, Infertility, Assisted Reproduction Technologies
- Trial name
- NCT07814235
- Where
- Spain
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- IVI Murcia
Pregnancy Outcomes
Does LAH May Improve the Pregnancy Outcomes?
A defect in the hatching stage is considered an important cause of implantation failure. Therefore, assisted hatching (AH), which involves artificial disruption of the zona pellucida, has been proposed as a method for improving…
- Trial name
- NCT03810157
- Testing
- Laser-assisted hatching system
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Neoplasms
Ovarian Tissue Cryopreservation and Subsequent Auto-Transplantation for Female Cancer Patients
Ovarian Tissue Cryopreservation will be provided to cancer patients to allow them to have their fertility preserved.
- Trial name
- NCT05830929
- Testing
- Ovarian tissue freezing and subsequent auto-transplantation after thawing
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- Chinese University of Hong Kong
Aortic Infections and Inflammations
Rolled Pericardium Versus Cryopreserved Allograft to Treat Native or Prosthetic Aortic Infection
While surgery with anatomic reconstruction of prosthetic aortic infections and native infectious aortitis has become established over time, the ideal substitute is not clearly defined.
- Trial name
- NCT06188819
- Testing
- Explantation of a previous aortic graft or endograft and reconstruction by arterial allograft or rolled pericardium
- Volunteers
- 150 people
- Sponsor
- University Paul Sabatier of Toulouse
Septic Shock, Sepsis
Umbilical Mesenchymal Stromal Cells as Cellular Immunotherapy for Septic Shock
Septic shock is associated with substantial burden in terms of both mortality and morbidity for survivors of this illness. Pre-clinical sepsis studies suggest that mesenchymal stem (stromal) cells (MSCs) modulate inflammation…
- Conditions
- Septic Shock, Sepsis, Pathologic Processes, Shock
- Trial name
- UC-CISSII (NCT05969275)
- Testing
- Allogeneic umbilical cord-derived human mesenchymal stromal cells
- Where
- 2 sites in Canada
- Volunteers
- 296 people
- Sponsor
- Ottawa Hospital Research Institute
Neoplasms, Gynecologic
rhTPO Mobilized Auto Cryo Platelets For GYN Patients Receiving Carboplatin
A Pilot Study of Transfusion of rhTPO-Derived Autologous Platelets Cryopreserved with ThromboSol and 2% DMSO in Patients with Gynecologic Malignancy Receiving Carboplatin
- Trial name
- NCT00038012
- Testing
- Thrombopoietin, Platelet-pheresis, Carboplatin
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- M.D. Anderson Cancer Center
Childhood Cancer, Fertility Disorders
Female Fertility Preservation Using Ovarian Tissue Cryopreservation Before Highly Gonadotoxic Cancer Treatment
Background: Due to the remarkable improvement in treatments these last decades, long term survival can be expected in more than 80% of childhood cancer patients.
- Trial name
- NCT03180827
- Testing
- ovarian tissue biopsy
- Where
- 2 sites in Switzerland
- Volunteers
- 100 people
- Sponsor
- Gumy-Pause Fabienne