Clinical trials: Cumulative Trauma Disorders
Carpal Tunnel Syndrome (CTS)
Comparing Efficacy of Osteopathic Manipulation vs. Wrist Immobilization for Carpal Tunnel Syndrome
Carpal Tunnel Syndrome (CTS) can be defined as disruption of the median nerve and is characterized by pain, numbness and tingling of the lateral 3.5 digits of the hand. In severe cases, motor function can also be disrupted.
- Trial name
- OMM (NCT07432750)
- Testing
- Osteopathic Manipulative Treatment, Wrist Immobilizer
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- New York Institute of Technology
Carpal Tunnel Syndrome
Single-portal Endoscopic Carpal Tunnel Release Versus Knifelight for Carpal Tunnel Syndrome. A Randomized Control Trial
The purpose of this study is to determine whether Single-portal Endoscopic Carpal Tunnel Release (Agee technique, SmartRelease™, MicroAire) and mini-open technique (Knifelight®, Stryker) are equally effective and safe surgical…
- Trial name
- CTS-HV (NCT01756820)
- Testing
- Single-portal Endoscopic Carpal Tunnel Release (Microaire®), Knifelight
- Where
- Greece
- Sponsor
- University of Ioannina
Overuse Injury
Effects of Strength Training on Musculoskeletal Overuse Injuries in Female Runners
The purpose of this study is to look at the effect of strength training in preventing overuse injuries in female runners
- Trial name
- STARS (NCT03080246)
- Testing
- Strength Training Exercise
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Carpal Tunnel Syndrome
Mulligan Mobilization With Arm Movement in CTS Patients
The aim of this study was to investigate the effect of the Mulligan Spinal Mobilization with Arm Movement technique on pain, grip strength and functionality in individuals with carpal tunnel syndrome and to compare it with the…
- Trial name
- NCT07042542
- Testing
- Mulligan Spinal Mobilization with Arm Movement, Conventional Neurodynamic Mobilization, Tendon Gliding and Hand Strengthening Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Beste Gebologlu
Overuse Injury
Alternate Run Study
The proposed study will investigate the effect of alternating footwear model and workout-type on the occurrence of running-related pain.
- Trial name
- NCT03082651
- Testing
- Alternating run training load, Alternating footwear, Constant training
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Carpal Tunnel Syndrome
The Volume Effect of Hydrodissection for Carpal Tunnel Syndrome
The investigators investigated the volume effect of hydrodissection for Injection therapies in patients with Carpal Tunnel Syndrome.
- Trial name
- NCT03598322
- Testing
- Dextrose 1mL injection, Dextrose 2mL injection, Dextrose 4mL injection
- Where
- Taiwan
- Volunteers
- 63 people
- Sponsor
- National Taiwan University Hospital
Carpal Tunnel Syndrome
Corticosteroid And Ozone Injection In Patıents With Carpal Tunnel Syndrome
There are a limited number of studies on the use of ozone in CTS.The aim of this clinical study is to compare the effectiveness of corticosteroid injections and ozone injections added to splint and exercise therapy in…
- Trial name
- NCT06237634
- Testing
- splint and exercise and advices, Triamsinolon Asetonid ozone, ozone
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Kayseri City Hospital
Carpal Tunnel Syndrome
Conditioning Electrical Stimulation to Improve Outcomes in Carpal Tunnel Syndrome
Carpal tunnel syndrome is common, identified in 3% of the general population. Symptoms including numbness and pain are due to compression of the median nerve as it travels through a tunnel entering the wrist and can result in…
- Trial name
- NCT04191538
- Testing
- Conditioning electrical stimulation, Postoperative electrical stimulation, No electrical stimulation
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- University of Alberta
Carpal Tunnel Syndrome
Correlation of Different Ultrasonographic Indices With Clinical Parameters in Carpal Tunnel Syndrome
The aim of this study is to investigate the relationship between different ultrasonographic indices used in patients with carpal tunnel syndrome and clinical parameters.
- Trial name
- NCT06115187
- Testing
- Nerve ultrasound, Nerve conduction studies
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Carpal Tunnel Syndrome
Median Nerve Stenosis in Carpal Tunnel Syndrome
The goal of this observational study is to test the new kind of ultrasound-based measurements in patients with carpal tunnel syndrome.
- Trial name
- NCT05861349
- Testing
- Nerve conduction study, Ultrasound
- Where
- Poland
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Jakub Antczak
Carpal Tunnel Syndrome
In Patients With Carpal Tunnel Syndrome, Median Nerve Conduction is Evaluated After Nerve Mobilizations
This project is linked to the line of research on carpal tunnel syndrome, of the PhysiUZerapy research group, belonging to the University of Zaragoza.
- Trial name
- NCT06399484
- Testing
- Manual mobilizations of the median nerve, Wrist movements
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad de Zaragoza
Carpal Tunnel Syndrome, PRP
PRP as Adjuvant Treatment to CTR for Severe CTS Tunnel Syndrome
This study assesses the potential benefit of adjuvant platelet-rich plasma (PRP) with carpal tunnel release (CTR) for patients with severe carpal tunnel syndrome (CTS).
- Trial name
- NCT04811287
- Testing
- Carpal Tunnel Release with Platelet-Rich Plasma, Carpal Tunnel Release without Platelet-Rich Plasma
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Michael Fredericson, MD
Carpal Tunnel Syndrome
Safety and Efficacy of a Device for the Relief of Pain Due to Carpal Tunnel Syndrome
Interventional study to evaluate efficacy and safety of an active splint.
- Trial name
- NCT03810326
- Testing
- CTR device (tradename named Xtend)
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yuinvent Innovations Ltd.
Knee Osteoarthritis
Efficacy and Safety of Hymovis ONE® (32mg/4ml) Intrarticular Injection in Active Patients With Knee Overuse Syndrome
The aim of this study is to evaluate the efficacy and safety of Hymovis® ONE (32 mg/4 ml) single intra-articular injection, in the management of pain caused by knee osteochondral lesions.
- Trial name
- NCT04661111
- Testing
- Hymovis® ONE (32 mg/4 ml)
- Where
- Italy
- Volunteers
- 31 people
- Sponsor
- Fidia Farmaceutici s.p.a.
Carpal Tunnel Syndrome
WALANT Versus Local Anesthesia With Tourniquet for Carpal Tunnel Decompression
This multicenter, randomized, double-blinded controlled trial compared two local anesthetic techniques for open carpal tunnel decompression in adults.
- Trial name
- WALANT vs LA-T (NCT07617064)
- Testing
- WALANT technique for carpal tunnel decompression, Local anesthesia with tourniquet for carpal tunnel decompression
- Where
- 2 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Misr University for Science and Technology
Carpal Tunnel Syndrome
Bilateral vs. Unilateral Neuromobilization in Carpal Tunnel Syndrome
This study aims to investigate whether bilateral (both extremities together) neuromobilization is superior to unilateral (only the affected side) neuromobilization in individuals diagnosed with Carpal Tunnel Syndrome.
- Trial name
- NCT06554405
- Testing
- Unilateral Intervention, Bilateral Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Gazi University
Mastectomy, Carpal Tunnel Syndrome (CTS)
Ultra Phonophoresis With a Hyaluronic Acid-Containing Gel on Carpal Tunnel Syndrome Post Mastectomy.
In this study, 60 patients will be randomly assigned into two equal groups (30 patients for each group): 1. Group A: This group will include 30 patients who will receive Ultra Phonophoresis with a hyaluronic acid-containing gel 5…
- Trial name
- NCT06538818
- Testing
- Ultra Phonophoresis
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Carpal Tunnel Syndrome
Intraneural Facilitation as a Treatment for Carpal Tunnel Syndrome
We hypothesize that a standard course of INF can result in significant improvement in CTS as measured by clinical, electrodiagnostic, or ultrasound measures.
- Trial name
- NCT03205683
- Testing
- Intraneural facilitation (INF)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Carpal Tunnel Syndrome (CTS)
Graded Motor Imagery in Carpal Tunnel Syndrome
The aim of this study is to investigate whether the addition of Graded Motor Imagery (GMI) to progressive neurodynamic exercises is more effective than progressive neurodynamic exercises alone in individuals with carpal tunnel…
- Trial name
- NCT07800260
- Testing
- Graded Motor Imagery (GMI), Progressive Neurodynamic Exercise, Nighttime Resting Splint
- Volunteers
- 46 people
- Sponsor
- Artvin Coruh University
Carpal Tunnel Syndrome
The Effect of Platelet Rich Plasma for Carpal Tunnel Syndrome
The platelet rich plasma (PRP) is a new and potential treatment for patients with kinds of musculoskeletal disorders. Although few studies have showed beneficial effect of PRP for regeneration of peripheral neuropathy in animal…
- Trial name
- NCT02539186
- Testing
- platelet rich plasma, splint
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Tri-Service General Hospital (TSGH)