Clinical trials: Curcumin
Healthy Participants
Pilot Assessment of the Safety of a Combination of Curcumin, Omega-3, and Vitamin D Supplements in ACPA+ Individuals
The goal of this clinical trial is to determine if the level of Anti-cyclic citrullinated peptide antibody (ACPA) is altered after taking curcumin, omega-3, and vitamin D supplements (COD) for 3 months.
- Trial name
- PASCOD3 (NCT06478290)
- Testing
- curcumin, omega-3, and vitamin D (COD)
- Where
- 2 sites in Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Covid-19
Oral Curcumin, Quercetin and Vitamin D3 Supplements for Mild to Moderate Symptoms of COVID-19
The present study is aimed to investigate the treatment benefits of a combination of dietary supplements quercetin, curcumin and vitamin D3 as add-on therapy to the routine care for early mild symptoms of COVID-19 infection in…
- Trial name
- NCT04603690
- Testing
- Complementary therapy, Standard of care
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Liaquat University of Medical & Health Sciences
Tinnitus, Subjective
Effect of Highly Bioavailable Curcumin on Subjective Tinnitus
This study will assess the effectiveness of highly bioavailable curcumin in suppressing subjective tinnitus based on pre- and post-treatment evaluations using the validated Tinnitus Functional Index (TFI) and Tinnitus Handicap…
- Trial name
- NCT04800107
- Testing
- Curcumin-phosphatidylcholine
- Where
- 3 sites in United States
- Sponsor
- Henry Ford Health System
Healthy
Pharmacokinetic Study on Three Formulations of Curcumin With Different Carriers
Curcumin is a molecule soluble in fat. It has multiple health benefits. Indeed, it has anti-inflammatory and anti-oxidant properties.
- Trial name
- NCT04382014
- Testing
- MAG fish oil + Curcumin OR Rice bran oil + Curcumin OR Curcumin extract
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Joint, Joint Diseases
Flexy3 Supplementation and Joint Health
The prevalence of osteoarthritis (OA) of the knee, hip, and hand has been estimated at 20% to 30% in the adult population (Neogi and Zhang, 2012).
- Trial name
- NCT07349264
- Testing
- Flexy3 Supplement (OriactivTM, Flexy3, Malaysia)
- Where
- Malaysia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- NXTVSION SDN. BHD.
Atopic Asthma
Effect of Supplemental Oral Curcumin in Patients With Atopic Asthma
Curcumin has antioxidant properties and in animal models has numerous molecular targets, many of which are intracellular, such as transcription factors AP-1 and NF.
- Trial name
- CURCUMIN (NCT01179256)
- Testing
- CURCUMIN, no intervention other than stopping study
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of South Florida
Periodontitis
A Clinical Trial to Study the Effect of a Drug, Curcumin in Patients With Periodontitis
The study will follow a parallel arm, randomised, double blinded, placebo controlled design. There will be two groups Group 1 = receiving 1% curcumin chips after routine scaling and root planing (n=20) Group 2 = receiving placebo…
- Trial name
- NCT03790605
- Testing
- 1 % curcumin chip, Scaling and root planing
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- KLE Society's Institute of Dental Sciences
Hematoma, Subdural, Chronic
Curcumin/Turmeric as a Treatment for Patients With Subdural Hematomas Recurrence
Our long-term objective is to evaluate the efficacy of curcumin (CC) in preventing a recurrence of chronic subdural hematoma (cSDH) following surgical evacuation.
- Trial name
- CACTIS (NCT03845322)
- Testing
- Curcumin Pill
- Where
- United States
- Sponsor
- University of New Mexico
Bioavailability
Theracurmin vs Curcumin Bioavailability Study
A randomized, open-label, cross-over, single administration study to compare bioavailability of curcumin in health adults
- Trial name
- NCT04028739
- Testing
- curmin
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Handok Inc.
Osteoarthritis, Knee Pain Chronic
Effectiveness of Curcumin-based Food Supplement in Reducing Pain and Inflammatory Component in Osteoarthritis
INTRODUCTION The treatment of OA is mostly symptomatic and includes the use of analgesics, NSAIDs, exercise and even surgery. However, the use of long-term NSAIDs is associated with potentially serious side effects.
- Trial name
- FENOXI-1900 (NCT04207021)
- Testing
- Experimental: Curcumin derivate
- Volunteers
- 134 people
- Sponsor
- KOS Care SRL - Istituto di Riabilitazione Santo Stefano
Ulcerative Colitis
Bio-enhanced Curcumin as an Add-On Treatment in Mild to Moderate Ulcerative Colitis
Inflammatory Bowel Disease, including ulcerative colitis, is thought to result from an imbalance of pro-inflammatory and anti-inflammatory factors.
- Trial name
- NCT02683733
- Testing
- Bio-enhanced Curcumin Soft Gelatin Capsule, 5-Aminosalicylic acid
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Asian Institute of Gastroenterology, India
Cervical Intraepithelial Neoplasia
Effect of Curcumin in Treatment of Squamous Cervical Intraepithelial Neoplasias (CINs)
The purpose of this study is to determine the safety, feasibility, and regression rate of using curcumin in patients with Cervical Intraepithelial neoplasias (CIN3).
- Trial name
- NCT02554344
- Testing
- Curcumin
- Where
- United States
- Sponsor
- Baylor Research Institute
PreDiabetes
Effect of Oral Supplementation With Curcumin on Insulin Sensitivity in Subjects With Prediabetes
This study evaluates the effects of oral supplementation with curcumin on the insulin sensitivity in subjects with prediabetes. The half of participants will receive curcumin and bioperine in combination, while the other half…
- Trial name
- NCT03917784
- Testing
- Curcumin, Starch
- Where
- Mexico
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Hospital General de México Dr. Eduardo Liceaga
Type 2 Diabetes, Pre-diabetes
Curcumin Therapy in Patients With Impaired Glucose Tolerance and Insulin Resistance
The incidence rate of type 2 diabetes in Thai populations is high and increasing every year. Cardiovascular disease is the main complication of this disease, which has been defined as an important cause of death among Diabetic…
- Conditions
- Type 2 Diabetes, Pre-diabetes, Insulin Resistance, Cardiovascular Risk
- Trial name
- NCT01052025
- Testing
- Curcumin
- Where
- Thailand
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Srinakharinwirot University
Contiguous Stage II Small Lymphocytic Lymphoma, Noncontiguous Stage II Small Lymphocytic Lymphoma
Curcumin and Cholecalciferol in Treating Patients With Previously Untreated Stage 0-II Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
This phase II trial studies the efficacy (activity), and tolerability of curcumin and cholecalciferol combination in treating patients with previously untreated stage 0-II chronic lymphocytic leukemia or small lymphocytic…
- Conditions
- Contiguous Stage II Small Lymphocytic Lymphoma, Noncontiguous Stage II Small Lymphocytic Lymphoma, Stage 0 Chronic Lymphocytic Leukemia, Stage I Chronic Lymphocytic Leukemia
- Trial name
- NCT02100423
- Testing
- curcumin, cholecalciferol, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Paolo Caimi, MD
Prostate Cancer, Radiation Therapy
Radiosensitizing and Radioprotectve Effects of Curcumin in Prostate Cancer
Prostate cancer is the second most incident cancer among male population worldwide. Radiation therapy by itself or along with surgery and chemotherapy are the main treatments for prostate cancer however prostate cancer cells are…
- Trial name
- NCT01917890
- Testing
- Curcumin
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Breast Cancer
A "Window Trial" on Curcumin for Invasive Breast Cancer Primary Tumors
The purpose of this study is to determine whether oral administration of curcumin causes biological changes in primary tumors of breast cancer patients.
- Trial name
- NCT03980509
- Testing
- Curcumin
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Medical University of South Carolina
Long COVID
Study to Investigate the Health Benefits of a Quercetin/Curcumin-Based Supplement for Mild to Moderate Long COVID-19 Symptoms
This pragmatic clinical study aims to evaluate the efficacy and tolerance of a combined quercetin/curcumin supplement in adults experiencing mild to moderate symptoms of Long COVID-19.
- Trial name
- NCT06974058
- Testing
- Nasafytol® (Quercetin/Curcumin Supplement)
- Where
- Pakistan
- Volunteers
- 15 people
- Sponsor
- Liaquat University of Medical & Health Sciences
Advanced Colorectal Cancer
Effect of Curcumin on Dose Limiting Toxicity and Pharmacokinetics of Irinotecan in Patients With Solid Tumors
Curcumin is an extract of the tumeric root that has been shown to have anti-tumor properties in laboratory studies. Curcumin, and its parent spice, turmeric (curcuma longa), are the 4th most commonly purchased dietary supplement…
- Trial name
- NCT01859858
- Testing
- curcumin, Irinotecan
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
COVID-19
Nutritional Supplementation of Flavonoids Quercetin and Curcumin for Early Mild Symptoms of COVID-19
The purpose of this study is to investigate the therapeutic benefits of flavonoids nutritional supplements quercetin and curcumin for early mild symptoms of COVID-19.
- Trial name
- NCT05130671
- Testing
- Standard of care, Investigational treatment
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- King Edward Medical University