Clinical trials: Curcumin
Pediatric Patients Having Renal Failure and on Regular Hemodialysis
Effects of Curcumin on Inflammation and Oxidative Stress in Pediatric Patients on Regular Hemodialysis: A Randomized, Double-Blind, Placebo-Controlled Pilot Study
The study will be a randomised, double blinded, placebo controlled design. It will include 2 groups : trial group and placebo group Patients in both groups are children on regular hemodialysis The patients in the trial group will…
- Trial name
- NCT05627843
- Testing
- Curcumin capsules 1 gm
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Healthy
Bioavailability of Curcuminoids From Turmipure Gold® in Different Food Matrices
The goal of this clinical trial is to learn about the extent to which turmeric compounds in different food matrices becomes available to the body in healthy volunteers.
- Trial name
- NCT06300021
- Testing
- TPG capsule, TPG ready to drink, TPG dairy analog
- Where
- France
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Givaudan France Naturals
Schizophrenia, Schizoaffective Disorder
Open-label Study of Curcumin C-3 Complex in Schizophrenia
Current evidence suggests that schizophrenia as a serious and complex psychiatric disorder, continues to challenge mental health professionals in their search for better treatment options in the community.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Depression
- Trial name
- NCT01875822
- Testing
- Super-Curcumin
- Where
- Puerto Rico
- Volunteers
- 17 people
- Sponsor
- Woodbury, Michel, M.D.
Diabetic Retinopathy
Anti-inflammatory Effect of Curcumin, Homotaurine, Vitamin D3 on Human Vitreous in Patients With Diabetic Retinopathy
Dosage of pro-inflammatory cytokines and soluble mediators (TNFα, IL6, IL2 and PDGF-AB) performed on 25 vitreous biopsies taken from patients with diabetic retinopathy and treated with increasing doses of curcumin (0.5uM and…
- Trial name
- NCT04378972
- Testing
- curcumin, homotaurine, vitamin D3, control
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- University of Molise
Familial Adenomatous Polyposis, FAP
Turmeric Supplementation on Polyp Number and Size in Patients With Familial Adenomatous Polyposis.
A Phase 2, randomized, double blind, placebo controlled trial for the effectivness of wholistic turmeric supplementation on polyp burden mong patients with Familial Adenomatouse Polyposis (FAP).
- Conditions
- Familial Adenomatous Polyposis, FAP, FAP Gene Mutation
- Trial name
- NCT03061591
- Testing
- Wholistic Turmeric capsules
- Volunteers
- 40 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Exercise-induced Muscle Soreness, Exercise-induced Joint Pain
Effects of Eggshell Membrane and Curcumin Extract Supplementation, Separately or Combined, on Recovery From Intense Exercise
Eggshell membrane and Curcumin supplementation prior to intense exercise may reduce inflammation, muscle and joint pain, and promote recovery.
- Conditions
- Exercise-induced Muscle Soreness, Exercise-induced Joint Pain, Exercise-induced Joint Stiffness, Exercise-induced Cartilage Turnover
- Trial name
- NCT07766720
- Testing
- NEM® brand eggshell membrane powder, curQ+® brand highly absorbable curcumin, NEM® plus curQ+® combination
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ESM Technologies, LLC
Obesity in Childhood
Non-Pharmacologic Alternatives for Childhood Obesity
Childhood obesity is a global health issue. Mexico has been considered as the country with the higher number of children with obesity. There are not approved drugs to support diet and exercise as the first step to lose weight.
- Trial name
- NCT03670875
- Testing
- Agave inulin, Curcumin, O3FA
- Where
- Mexico
- Volunteers
- 300 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Chronic Kidney Diseases, Diabetes Mellitus, Type 2
Curcumin on NFE2L2 Gene Expression, Antioxidant Capacity and Renal Function According to rs35652124 in Diabetic Nephropathy
The increase in the prevalence of diabetes mellitus (DM) is one of the greatest public health challenges worldwide. Epidemiological studies have shown that DM is the leading cause of chronic kidney disease (CKD) in patients…
- Conditions
- Chronic Kidney Diseases, Diabetes Mellitus, Type 2, Polymorphism
- Trial name
- CURCUNRF2 (NCT03262363)
- Testing
- Curcumin/NFE2L2 A>G
- Where
- Mexico
- Volunteers
- 176 people
- Sponsor
- Unidad de Investigacion Medica en Enfermedades Renales
Osteosarcoma
Pilot Study of Curcumin Formulation and Ashwagandha Extract in Advanced Osteosarcoma
Curcumin as well as the ashwagandha extract are ingredients from traditional indian medicine and have been shown to be potent anti-cancer compounds in laboratory as well as animal studies.
- Trial name
- OSCAT (NCT00689195)
- Testing
- Curcumin powder, Ashwagandha extract
- Where
- India
- Volunteers
- 24 people
- Sponsor
- Tata Memorial Hospital
Cardiovascular Risk Factor
Effect of Curcumin on Microvascular Response and Tissue Oxygenation
Aging has been associated with reduced bioavailability of nitric oxide(NO) and endotelial dysfunction.Curcumin, a phenolic compound present in the rhizomes of turmeric, possesses cardiovascular protective, anti-inflammatory and…
- Trial name
- NCT04119752
- Testing
- Curcumin powder
- Where
- Brazil
- Volunteers
- 28 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Post-acute COVID-19 Syndrome
The Effect of Micellized Food Supplements on Health-related Quality of Life in Patients With Post-acute COVID-19 Syndrome.
Food supplements like curcumin and boswellia serrata have been used traditionally for anti-inflammatory purposes. A well-known problem of these substances in their natural form is the low bioavailability.
- Trial name
- NCT05150782
- Testing
- Curcumin/Boswellia Serrata/Ascorbic acid mixture
- Volunteers
- 32 people
- Sponsor
- PhysioMetrics
Proteinuria
Effect of Oral Supplementation With Curcumin in Patients With Proteinuric Diabetic Kidney Disease
The purpose of this study is to determine if the oral supplementation with curcumin reduces proteinuria, improves the redox and pro-inflammatory state in patients with chronic kidney disease associated to Diabetes mellitus.
- Trial name
- NCT03019848
- Testing
- Curcumin
- Where
- Mexico
- Volunteers
- 100 people
- Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez
Periodontitis, Adult
Clinical Efficacy of NST With Adjunctive Local Delivery of Ozonated Olive Versus Curcumin Gel in Stage II Grade B Periodontitis.
The aim of this clinical trial is to evaluate the effectiveness of local delivery ozonated olive gel versus curcumin gel as adjunct to scaling and root planing in the treatment of stage II grade B periodontitis in on both males…
- Trial name
- NCT07184268
- Testing
- full mouth non-surgical scaling
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontitis
Efficacy of Nano-Curcumin and Nano-Hyaluronic Acid as an Adjunct to Scaling and Root Planing in the Treatment of Periodontitis
to evaluate Efficacy of Locally Applied Nano-Curcumin and Nano-Hyaluronic Acid as an Adjunct to Scaling and Root Planing in the Treatment of Periodontitis patients Materials and methods: forty patients (n=40) were selected from…
- Trial name
- NCT06777303
- Testing
- curcurmin loaded on chitosan nano-particles, hyaluronic acid loaded on chitosan nano-particles, scaling and root planning
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Migraine
The Combined Effects of omega3 Fatty Acids and Curcumin Supplementation on Inflammatory and Endothelial Factors in Migraine Patients
The aim of this study is to determine the effects of omega 3 fatty acid, curcumin and their combination or placebo for 2 months on the gene expression of COX-2, iNOS, TNF-α, IL-1β, IL-6, VCAM-1 and ICAM-1 in the peripheral blood…
- Trial name
- NCT02532023
- Testing
- omega 3 fatty acid, curcumin
- Volunteers
- 80 people
- Sponsor
- Tehran University of Medical Sciences
Prostate Cancer
Adjuvant Curcumin to Assess Recurrence Free Survival in Patients Who Have Had a Radical Prostatectomy
This is a prospective study to determine if the adjuvant use of Curcumin improves recurrence-free survival.
- Trial name
- NCT02064673
- Testing
- Curcumin
- Where
- United States
- Volunteers
- 650 people
- Sponsor
- yair lotan
Amyotrophic Lateral Sclerosis
Impact of the Combined Treatment of Liposomed Polyphenols With G04CB02 on the ALS Patients
Amyotrophic lateral sclerosis (ALS) is a disease of an inflammatory nature, which causes progressive muscle weakness associated with cognitive and behavioural disorders.
- Trial name
- NCT04654689
- Testing
- Liposomed polyphenols resveratrol and curcumin, Isocaloric Diet, G04CB02
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Fundación Universidad Católica de Valencia San Vicente Mártir
Oral Mucositis, Pediatric Cancer
Curcumin VS Photo-bio-modulation Therapy of Oral Mucositis in Pediatric Patients Undergoing Anti-Cancer Non-invasive Treatment
The main objective of this study is to assess the impact of non-invasive photodynamic therapy by Curcumin and photo-bio-modulation low level (LL) laser treatment in managing mucositis induced by chemotherapy in pediatric…
- Trial name
- NCT06044142
- Testing
- Curcumin, Laser
- Where
- Saudi Arabia
- Volunteers
- 90 people
- Sponsor
- Riyadh Elm University
Diabetes
Effects of Curcumin on Postprandial Blood Glucose, and Insulin in Healthy Subjects
Previous animal studies have shown that extracts of Curcumin lowers blood glucose.
- Trial name
- NCT01029327
- Where
- Sweden
- Volunteers
- healthy volunteers welcome
- Sponsor
- Skane University Hospital