Clinical trials: Cyst
Wound Infection, Primary Closure
Comparison of Primary Closure Vs Open Wound in Pilonidal Sinus Excision.
The goal of this randomized clinical trial is to compare wound infection rates after two surgical techniques for treating pilonidal sinus in adults.
- Conditions
- Wound Infection, Primary Closure, Sacrococcygeal Pilonidal Sinus, Pilonidal Sinus Treatment
- Trial name
- NCT07798752
- Testing
- Primary Closure Technique, Open Technique
- Where
- Pakistan
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Hayatabad Medical Complex
Odontogenic Cyst
Recurrence of Odontogenic Keratocyst
The aim of current cross over clinical trial is to evaluate the effect of topical 5-FU as adjunct therapy in reducing risk of the recurrence of OKCs
- Trial name
- NCT06071806
- Testing
- Topical Application of 5-Fluorouracil
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Tanta University
Polycystic Ovary Syndrome
Obesity and Clinical Presentation of Hyperandrogenism
Polycystic Ovarian Syndrome (PCOS) is the most common endocrine disorder in reproductive women. It is estimated that 5 to 10% of women of reproductive age have PCOS.
- Trial name
- NCT01114633
- Where
- Taiwan
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University WanFang Hospital
Polycystic Ovary Syndrome
Study to Assess Potential Impairments in Estradiol Augmentation of Gonadotropin Secretion in Polycystic Ovary Syndrome
The purpose of this study is to determine if estradiol augmentation of luteinizing hormone (LH) secretion secretion (primary endpoint) and follicle-stimulating hormone (FSH) secretion (secondary endpoint) is reduced in adult…
- Trial name
- CRM009 (NCT03401047)
- Testing
- Estradiol
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Polycystic Ovary Syndrome, Hypovitaminosis D
The Effect of Vitamin D Supplementation Among Overweight Jordanian Women With Polycystic Ovary Syndrome (PCOS)
This is a prospective double-blind, randomized, parallel-group, placebo-controlled trial designed to examine the effect of supplementation with 50,000 IU vitamin D3 for 3 months on Polycystic Ovary Syndrome (PCOS) prognosis…
- Trial name
- NCT02328404
- Testing
- 50,000 IU vitamin D3
- Where
- Jordan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hayat Pharmaceutical Co. PLC
Pancreatic Cancer, Pancreatic Cyst
Improving Pancreatic Cancer Care by the Use of Computational Science and Technology
The goal of the IMPACT project is to set up a data sharing infrastructure between expert centers for pancreatic surgery that enables training, testing and validation of computer science tools to improve quality of care for…
- Conditions
- Pancreatic Cancer, Pancreatic Cyst, Pancreatic Adenocarcinoma, Pancreatic Diseases
- Trial name
- IMPACT (NCT06055010)
- Testing
- No interventions
- Where
- Netherlands
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Periapical Diseases, Radicular Cyst
PRF Membrane and Recovery After Periapical Surgery: A 3D Imaging Study
The goal of this clinical trial is to determine whether a PRF (platelet-rich fibrin) membrane helps improve recovery after periapical surgery in adults.
- Conditions
- Periapical Diseases, Radicular Cyst, Granuloma, Postoperative Complications
- Trial name
- NCT06739200
- Testing
- Platelet-Rich Fibrin (PRF) Membrane
- Where
- Hungary
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
PCOS, Polycystic Ovary Syndrome
Androgen Blockade and Progesterone Augmentation of Gonadotropin Secretion
This study is trying to find out if flutamide (a medication that blocks the effects of testosterone) may help normalize an aspect of pituitary function (specifically, gonadotropin surge generation) in PCOS.
- Trial name
- CRM010 (NCT04597099)
- Testing
- Micronized progesterone, Flutamide, Estradiol patch
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Insulin Resistance, Polycystic Ovary Syndrome
Determinants of Insulin Sensitivity by Age, Sex, Race/Ethnicity, BMI, and PCOS Diagnosis
The study aims to investigate the relationship between fasting insulin and Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) across various demographic factors, including age, sex, race/ethnicity, BMI, and polycystic…
- Conditions
- Insulin Resistance, Polycystic Ovary Syndrome, Hyperinsulinism, Obesity
- Trial name
- DAISY (NCT05950282)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ali Chappell
Hyperandrogenemia, Polycystic Ovary Syndrome
Assessment of Sensitivity of the Hypothalamic GnRH Pulse Generator to Estradiol and Progesterone Inhibition
Gonadotropin-releasing hormone (GnRH) is a hormone that regulates the ability of the pituitary to secrete two hormones, luteinizing hormone (LH) and follicle-stimulating hormone (FSH).
- Trial name
- JCM026 (NCT01428245)
- Testing
- Progesterone, Estrace (estrogen)
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Polycystic Ovary Syndrome
The Genetics of Polycystic Ovarian Syndrome
The goal of this study is to determine the genetic basis of polycystic ovary syndrome (PCOS). We will first look for genes in the Icelandic population, where large family trees are known and it is easier to search for genes.
- Trial name
- NCT00166569
- Where
- United States
- Volunteers
- 2,700 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Polycystic Ovary Syndrome
Combined Chromium With Letrozole Versus Letrozole Only in Induction of Ovulation in Patients With Polycystic Ovary Syndrome
Combined letrozole with chromium versus letrozole only in induction of ovulation in polycystic ovary syndrome
- Trial name
- NCT05765305
- Testing
- Letrozole with chromium
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Polycystic Ovary Syndrome
L-Carnitine and Clomiphene Citrate for Induction of Ovulation in Women With Polycystic Ovary Syndrome
The purpose of the study to assess the efficacy of adding L-carnitine to clomiphene citrate for increasing the ovulation and the pregnancy rate in women with PCOS.
- Trial name
- NCT03476356
- Testing
- oral clomiphene citrate, oral carnitine supplementation
- Where
- Egypt
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pancreatic Cancer
Role of the Cystic Fluid Interleukins and Tumor Necrosis Factor (TNF) Levels in Characterizing Pancreatic Cysts Detected by Endoscopic Ultrasound (EUS)
This study aims to find a correlation between cytokines levels and malignancy potential of different cystic types.
- Trial name
- NCT03178812
- Testing
- EUS with fine-needle aspiration of pancreatic cyst, Laboratory Blood test
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Polycystic Ovary Syndrome
Letrozole Dose Increments in PCOS Patients Resistant to Letrozole
Objectives: To study the effect of Letrozole dose increments on ovulation rate and endometrial thickness as a primary outcomes in patients with polycystic ovary syndrome who previously resistant to letrazole conventional dose…
- Trial name
- NCT06403488
- Testing
- Letrozole 2.5mg
- Where
- 2 sites in Egypt
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Polycystic Ovary Syndrome
Polycystic Ovary Syndrome - Improving Outcomes
Polycystic ovary syndrome affects a striking 9-18% of Australian reproductive aged women and has been associated with a number of metabolic abnormalities.
- Trial name
- NCT01504321
- Testing
- Moxonidine
- Where
- Australia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Baker Heart and Diabetes Institute
Treatment Resistant Disorders
Adding L-carnitine in Clomiphene Resistant Polycystic Ovary Improves the Quality of Ovulation and the Pregnancy Outcome
Adding L-carnitine is more successful than clomiphene as a first line therapy for ovulation induction in women with clomiphene resistant PCOS
- Trial name
- NCT01665547
- Testing
- l-carnitine
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Woman's Health University Hospital, Egypt
Poly Cystic Ovary Syndrome
The Effect Of Polycystic Ovarian Syndrome Treatment On Ocular Surface.
This is a Descriptive prospective cohort study conducted at the Ophthalmology Department in Kasr-Alaini Hospital. A total of 90 subjects, 30 control females with no relevant medical, gynecological or ophthalmic history, and 60…
- Trial name
- NCT07419776
- Testing
- dry eye diagnostic system of Mediworks, Optical coherence tomography angiography, Contraceptives, Oral, Combined
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Polycystic Ovary Syndrome, Anovulation
The Effect of Metformin Added to Clomiphene Citrate on Pregnancy Rates in Hyperandrogenic, Chronic Oligoovulatory or Anovulatory Women
The purpose of our study was to conduct a placebo controlled, double-blind randomized trial in chronic oligoovulatory or anovulatory , hyperandrogenic, infertility patients comparing the effects of adjuvant metformin plus…
- Conditions
- Polycystic Ovary Syndrome, Anovulation, Oligoovulation, Infertility
- Trial name
- NCT00413179
- Testing
- Metformin, Clomiphene citrate
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- 59th Medical Wing
Polycystic Ovary Syndrome, Metformin
Effects of Metformin on Metabolic and Reproductive Outcomes in Chinese PCOS Patients
Polycystic ovary syndrome (PCOS) is a reproductive endocrine disease characterized by reproductive and metabolic abnormalities, which is a crucial cause of female infertility and an essential risk factor for type 2 diabetes.
- Trial name
- NCT05463627
- Testing
- Metformin
- Where
- China
- Volunteers
- 1,440 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital