Clinical trials: Cystitis
Neurodegenerative Diseases, Osteoarthritis
Safety and Clinical Outcomes Study: SVF Deployment for Orthopedic, Neurologic, Urologic, and Cardio-pulmonary Conditions
To evaluate for any adverse effects that may be related to the administration and reception of autologous adipose derived stromal vascular fraction (SVF).
- Conditions
- Neurodegenerative Diseases, Osteoarthritis, Erectile Dysfunction, Autoimmune Diseases
- Trial name
- NCT01953523
- Testing
- Administration of autologous adipose derived SVF
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Elliot Lander
Urologic Injuries, Urologic Diseases
Bladder Morphology Using 2 Different Catheter Designs
Demonstrate and compare the 3D morphology of the bladder wall in full and drained states with 2 different kinds of bladder catheters in place. (Foley Catheter vs. Cystosure Catheter)
- Conditions
- Urologic Injuries, Urologic Diseases, Bladder Infection, Urinary Tract Infections
- Trial name
- NCT03108079
- Testing
- Cystosure Urinary Access System, Foley Catheter
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- The Pelvic Floor Institute
Interstitial Cystitis, Irritable Bowel Syndrome
MAPP Investigation of Pelvic Floor-Brain Neurobiologic Axis in IC/IBS and IBS
Hypotheses: 1. The bidirectional signaling between the cortex, and the pelvic floor/gut is deranged in patients with IC and in IBS.
- Trial name
- NCT01280864
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Augusta University
Pelvic Lipomatosis, Cystitis Glandularis
Efficacy of UMT in CG Patients With PL
To clinically validate the pathological role of Cer accumulation and evaluate a novel microbiota-targeted intervention, we conducted a comprehensive analysis of bladder mucosal specimens from a well-characterized patient cohort…
- Trial name
- NCT07530627
- Testing
- Urinary Microbiota Transplantation (UMT)
- Where
- China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Urinary Tract Infection
Single Dose Monurol for Treatment of Acute Cystitis
Urinary tract infecton (UTI) is a very common problem in young healthy women, afflicting approximately one-half of women by their late 20's.
- Trial name
- NCT00976963
- Testing
- TMP/SMX, Fosfomycin
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Washington
Interstitial Cystitis
Quantitative Studies of Urinary Bladder Sensation
The purpose of this study is to determine whether more than one subpopulation exists of patients with the diagnosis of Interstitial Cystitis (IC) based on sensory testing and to determine if subjects with IC have normal…
- Trial name
- NCT00903435
- Testing
- Quantitative Sensory Testing and Stimulus
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Timothy Ness, MD
Fibromyalgia, Irritable Bowel Syndrome
Observational Study of Control Participants for the MAPP Research Network
The Control Study for the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network has been established to focus on a broader approach to the study of Interstitial Cystitis (IC)/Painful Bladder…
- Conditions
- Fibromyalgia, Irritable Bowel Syndrome, Fatigue Syndrome, Chronic
- Trial name
- MAPP-Control (NCT01098292)
- Where
- 8 sites in United States
- Volunteers
- 615 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Urinary Tract Infections
COMPARISON OF NITROFURANTOIN WITH FOSFOMYCIN in TREATING CYSTITIS IN WOMEN
Fosfomycin and nitrofurantoin are increasingly being prescribed in outpatients for the oral treatment of urinary tract infection (UTI).
- Trial name
- NCT06518291
- Testing
- Nitrofurantoin 100 MG, Fosfomycin
- Volunteers
- 392 people, healthy volunteers welcome
- Sponsor
- Shalamar Institute of Health Sciences
Pelvic Floor Disorders, Interstitial Cystitis
Adverse Childhood Experiences in Urogynecologic Patients
Adverse Childhood Experiences (ACEs) have been associated with negative health outcomes, yet scant information exists regarding the relationship between ACEs, Pelvic floor disorders, and Chronic Pelvic Pain.
- Conditions
- Pelvic Floor Disorders, Interstitial Cystitis, Urinary Incontinence
- Trial name
- ACE-UP (NCT03480477)
- Testing
- ACE questionnaire
- Where
- United States
- Volunteers
- 356 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Interstitial Cystitis, Painful Bladder Syndrome
IC PaIN Trial: Interstitial Cystitis Pain Improvement With Naltrexone
Interstitial cystitis/painful bladder syndrome (IC/PBS) is a debilitating condition with symptoms of urinary urgency, frequency, nocturia (waking up at night to void), and pain, without evidence of urinary tract infection or…
- Conditions
- Interstitial Cystitis, Painful Bladder Syndrome, Bladder Pain Syndrome, Low Dose Naltrexone
- Trial name
- NCT04313972
- Testing
- low-dose naltrexone
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Prostatitis, Chronic Prostatitis
Microbiome of Urologic Chronic Pelvic Pain Syndrome
This research is being done to learn more about the bacteria that live in the genito-urinary tract in subjects with urologic chronic pelvic pain syndrome (UCPPS).
- Conditions
- Prostatitis, Chronic Prostatitis, Interstitial Cystitis, Painful Bladder Syndrome
- Trial name
- NCT03027076
- Testing
- Genitourinary Specimen Collection, Collect midstream urine samples
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cystitis, Urinary Tract Infections
Incidence of Cystitis in Women Consuming a Mixture of Cranberry, Cinnamon, Probiotics
Cranberries are traditionally used for urinary comfort and prevention of urinary disorders of bacterial origin and despite an EFSA opinion invalidating the clinical efficacy of cranberries, its mechanism of action has been…
- Trial name
- NCT04987164
- Testing
- Feminabiane CBU
- Where
- 2 sites in France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- CEN Biotech
Interstitial Cystitis, Painful Bladder Syndrome
Pilot Study of Percutaneous Posterior Tibial Nerve Stimulation for the Treatment of IC/PBS
In 2014, the American Urological Association updated it management algorithm for Interstitial Cystitis/Painful Bladder Syndrome (IC/PBS). As the algorithm progresses, interventions become increasingly invasive and morbid.
- Trial name
- NCT02550561
- Testing
- Posterior Tibial Nerve Stimulation
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Urinary Tract Infections
Single Dose Aminoglycosides for Acute Uncomplicated Cystitis in the Emergency Department Setting
The purpose of this research study is to determine if gentamicin is as effective treatment of acute uncomplicated cystitis (urinary tract infection) using aminoglycosides versus the current standards of care.
- Trial name
- NCT05702762
- Testing
- Gentamicin, Standard of Care
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Mercy Health Ohio
Urinary Tract Infection
Short Course Nitrofurantoin for Acute Cystitis
The purpose of this research study is to determine what the cure rates are with a 5 day course of nitrofurantoin versus the more standard 3 day course of trimethoprim/sulfamethoxazone.
- Trial name
- NCT00391651
- Testing
- Nitrofurantoin 100mg twice daily x 5 days, TMP/SMX DS twice daily x 3 days
- Where
- United States
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- University of Washington
Interstitial Cystitis, Bladder Pain Syndrome
The CBD-IC Randomized Controlled Trial: Evaluation of Hemp Cannabidiol SuppositoRies for Pain and Urinary SymptOms in INterstitial Cystitis (CHRONIC)
This study seeks to exploit bladder cannabidiol receptors as a therapeutic drug target by conducting a double-masked, placebo-controlled randomized trial evaluating the effects of vaginal hemp cannabidiol (CBD) suppositories on…
- Trial name
- CHRONIC (NCT04349930)
- Testing
- Cannabidiol vaginal suppository
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of New Mexico
Painful Bladder Syndrome
Sensory Processing in Subjects With Painful Bladder Syndrome
The purpose of this study is to determine if clinically relevant subsets exist in patients meeting the diagnosis of Painful Bladder Syndrome (PBS).
- Trial name
- NCT00903643
- Testing
- Physical examination
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Interstitial Cystitis, Chronic Prostatitis
Microbiomes of Pelvic Pain
This research study seeks to provide more insight as to how the microbiome affects or is affected by conditions causing chronic pelvic pain such as Interstitial Cystitis (IC), Chronic Prostatitis/Chronic Pelvic Pain Syndrome…
- Conditions
- Interstitial Cystitis, Chronic Prostatitis, Chronic Pelvic Pain Syndrome, Lower Urinary Tract Symptoms
- Trial name
- NCT01738464
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Acute Cystitis (Excl in Pregnancy)
Ibuprofen Versus Mecillinam for Uncomplicated Cystitis
Although uncomplicated cystitis is considered to be a mild condition and mostly self limiting, most patients who see a doctor will be treated with antibiotics.
- Trial name
- IMUTI (NCT01849926)
- Testing
- Ibuprofen, Mecillinam
- Where
- Norway
- Volunteers
- 383 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Interstitial Cystitis
Osteopathic Manipulation Therapy in the Treatment of Interstitial Cystitis
As a safe and noninvasive method of treatment, the intent of the study is to show that Osteopathic manipulation therapy is a beneficial treatment for the aggravating bladder symptoms seen in all patients with interstitial…
- Trial name
- NCT00873171
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- CAMC Health System