Clinical trials: DEGLUTİTİON
Head and Neck Neoplasms, Deglutition Disorders
EMST and Swallowing in Long-Term Survivors of HNCA
This study is a randomized trial examining the impact of expiratory muscle strength training (EMST) on oral intake, swallowing function, and swallow-related quality of life in persons treated for cancer of the head and neck…
- Trial name
- NCT03975465
- Testing
- Expiratory Muscle Strength Training, Pharyngeal Muscle Strengthening Exercises
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- University of Wisconsin, Milwaukee
Schizophrenia Disorder
AI-assisted Masticatory Muscle Training in Patients With Schizophrenia
Dysphagia seems to be quite common and potentially severe in schizophrenia, which may lead to acute asphyxia or pneumonia. Dysphagia in schizophrenia could be associated with drug-induced Parkinsonism, dystonia, tardive…
- Trial name
- AI-assisted (NCT07154407)
- Testing
- AI-assisted Mastisting Training App
- Volunteers
- 100 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Erosive Esophagitis(EE), Gastroesophageal Reflux Disease (GERD)
TAK-438 - Safety, Blood Levels & Effects of Repeated Doses
The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics of TAK-438 in healthy, non-Japanese men male subjects following a randomized, double blind, placebo controlled, sequential panel…
- Trial name
- TAK-438_107 (NCT02141711)
- Testing
- TAK-438
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Takeda
Acute Ischemic Stroke (AIS), Stroke-Associated Pneumonia (SAP)
Oral Care Strategies for Stroke Patients with Dysphagia
This study aims to evaluate whether combining neuromuscular electrical stimulation (NMES) with oral care can improve swallowing function in patients who have experienced an acute stroke and are dealing with dysphagia (difficulty…
- Conditions
- Acute Ischemic Stroke (AIS), Stroke-Associated Pneumonia (SAP), Dysphagia Following Cerebrovascular Accident
- Trial name
- NCT06692101
- Testing
- oral care, Neuromuscular Electrical Stimulation (NMES)
- Where
- Taiwan
- Volunteers
- 35 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Dysphagia
Esophageal Calibration During Laparoscopic Fundoplication Reduces Dysphagia
Gastro esophageal reflux is the most common benign disease of the esophagus and Laparoscopic Nissen fundoplication became the standard surgical treatment of this disease.
- Trial name
- NCT01501071
- Testing
- Esophageal calibration tube
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Antalya Training and Research Hospital
Stroke, Swallowing Disorders
Comparison of NMES, tDCS, and TMS Treatments in Post-Stroke Dysphagia
This randomized, single-blind, controlled clinical trial aims to compare the effectiveness of neuromuscular electrical stimulation (NMES) administered alone or in combination with transcranial direct current stimulation (tDCS) or…
- Conditions
- Stroke, Swallowing Disorders, Dysphagia
- Trial name
- NCT07793799
- Testing
- Neuromuscular Electrical Stimulation, Active Transcranial Direct Current Stimulation, Active Transcranial Magnetic Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Atlas University
Stroke, Dysphagia, Late Effect of Stroke
Investigating Program of Food Preparation on Diet Improvement for Patients With Stroke
This is a randomized controlled behavioral intervention trial to assess the efficacy of investigating program of food preparation on diet improve patients with stroke.
- Trial name
- NCT04347863
- Testing
- Group swallowing disorder diet preparation program
- Where
- Taiwan
- Volunteers
- 22 people
- Sponsor
- Taiwan Adventist Hospital
Gastroesophageal Reflux Disease
A Double-blind Comparative Study of the Efficacy and Safety of E3810 10mg Once and Twice Daily in Maintenance Therapy for PPI Resistant Gastroesophageal Reflux Disease Patients
The purpose of this study is to assess the efficacy and safety of rabeprazole 10mg once and twice daily in maintenance therapy for PPI resistant gastroesophageal reflux disease patients.
- Trial name
- NCT02135107
- Testing
- Rabeprazole
- Where
- 61 sites in Japan
- Volunteers
- 517 people
- Sponsor
- Eisai Co., Ltd.
Dysphagia
The Safety and Efficacy of the 4 Channel NMES on Swallowing
This study is a pilot study to prepare clinical trials to evaluate the safety and effectiveness of 4-channel electric stimulation therapy devices as a newly developed function for the treatment of dysphagia disorders.
- Trial name
- NCT03670498
- Testing
- 4 channel Electrical Stimulation Device, 2 channel Electrical Stimulation Device
- Where
- South Korea
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Achalasia, Gastroparesis
Disposable Endoscope Platform in Third Space Endoscopic Procedures
This is a prospective, single-arm unblinded study performed at a single tertiary center in the United States. All subjects will receive standard medical care and no experimental interventions are going to be performed.
- Trial name
- NCT06738628
- Testing
- (Esophageal or Gastric) Per-Oral Endoscopic Myotomy
- Where
- United States
- Sponsor
- Baylor College of Medicine
Gastroesophageal Reflux Disease (GERD)
A Study to Compare PK/PD Characteristics and Safety Profiles Between AD-120 and AD-120A
Primary endpoint of this study is to evaluate the pharmacokinetic and pharmacodynamic characteristics of AD-120 in healthy subjects.
- Trial name
- NCT06916130
- Testing
- AD-120A, AD-120
- Where
- South Korea
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Addpharma Inc.
Gastroesophageal Reflux Disease, Tooth Wear
Relationship Between Gastroesophageal Reflux Disease and Dental Erosion
This study aimed to investigate the relationship between gastroesophageal reflux disease (GERD) and dental erosion and the alterations in oral tissues. This was a case-control study.
- Trial name
- NCT04595500
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Beykent
Deglutition Disorders
DYsphAgia In Mechanically Ventilated ICU patientS
Dysphagia significantly contributes to morbidity and mortality in non-critically ill patients (as e.g. in stroke). Long term consequences of dysphagia include, among others, malnutrition, prolonged enteral tube feeding and…
- Trial name
- DYnAMICS (NCT02333201)
- Where
- Switzerland
- Volunteers
- 2,000 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Dyspepsia, Anemia
The Use of AI to Improve Quality of OGD
Early and accurate recognition of gastrointestinal lesions has implications for public health. The quality of oesophagogastroduodenoscopy (OGD) has great impact on the detection of oesophageal and gastric malignancies.
- Conditions
- Dyspepsia, Anemia, Acid Reflux, Dysphagia
- Trial name
- NCT04883567
- Testing
- The use of artificial intelligence system Cerebro
- Where
- Hong Kong
- Volunteers
- 210 people
- Sponsor
- Chinese University of Hong Kong
Gastroesophageal Reflux Disease, Heartburn
Efficacy and Safety of Sodium Alginate Oral Suspension to Treat Non-erosive Gastro-esophageal Reflux Disease
About 60% of patients with typical gastroesophageal reflux symptoms such as heartburn and regurgitation are considered to have non-erosive reflux disease (NERD).
- Trial name
- NCT01338077
- Testing
- Sodium alginate, Omeprazole
- Where
- Taiwan
- Volunteers
- 195 people
- Sponsor
- Chang Gung Memorial Hospital
Gastro Esophageal Reflux, Barrett Esophagus
PPI Therapy Impact on GERD After Sleeve Gastrectomy
The trial would to try to establish: The best post-operative PPI prescription protocol after Sleeve Gastrectomy The impact of PPI therapy on postoperative peptic diseases (erosive gastropathies, ulcers, duodenitis, esophagitis…
- Conditions
- Gastro Esophageal Reflux, Barrett Esophagus, Bariatric Surgery Candidate
- Trial name
- NCT04400136
- Testing
- Lansoprazole oral tablets 30 mg
- Where
- Italy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Acid Reflux
A Study to Investigate the Effect of ONO-8539 on Acid-Induced Oesophageal Hypersensitivity in Healthy Volunteers
A study to investigate the efficacy of ONO-8539 on acid-induced oesophageal hypersensitivity in healthy male adult volunteers.
- Trial name
- NCT01705275
- Testing
- ONO-8539
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ono Pharmaceutical Co., Ltd.
Pilates Exercise, Gastro Esophageal Reflux
Effects of Clinical Pilates Exercises on Symptoms, Posture, Balance and Quality of Life in GERD
This randomized, single-blind, parallel-group clinical trial investigates whether a six-week supervised clinical Pilates exercise program improves reflux symptom severity, postural alignment, dynamic balance, sleep quality…
- Trial name
- NCT07573280
- Testing
- Usual Daily Activity (No Exercise Intervention), Supervised Clinical Pilates Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Istinye University
Gastroesophageal Reflux Disease, Hiatal Hernia
Long-term Outcome of Laparoscopic Hiatal Hernia Repair With or Without Alloderm Mesh at a University Hospital
To study the long term outcome of Laparoscopic Hiatal Hernia Repair with human acellular dermal matrix Alloderm (LifeCell, Branchburg, NJ) mesh.
- Conditions
- Gastroesophageal Reflux Disease, Hiatal Hernia, Paraesophageal Hernia
- Trial name
- NCT01776827
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- University of Nebraska
GERD, Esophagitis
Esophageal Monitoring Device for Assessing Mucosal Impedance
The investigators are looking at a novel approach to measuring gastroesophageal reflux disease (GERD) damage and reducing the need for costly and less optimal testing presently used for diagnostic and treatment purposes.
- Trial name
- NCT01556919
- Testing
- Standard of care endoscopy
- Where
- United States
- Volunteers
- 429 people
- Sponsor
- Vanderbilt University
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