Clinical trials: DEGLUTİTİON
Esophageal Achalasia
Short Versus Long Submucosal Tunneling in Per-oral Endoscopic Myotomy (POEM) for Type II Achalasia.
this study is prospective , randomized and interventional ,will be performed on 50 patients to compare the clinical utility , safety profile and postoperative recovery metrics between short and long per-oral endoscopic myotomy …
- Trial name
- NCT07686471
- Testing
- per-oral endoscopic myotomy
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Severe Obesity, GERD
Comparison of the Sleeve Gastrectomy Technique With a Nissen Fundoplication Added to the Conventional Sleeve Gastrectomy Technique in Morbidly Obese Patients
The purpose of this study is to evaluate the impact of the procedure (sleeve gastrectomy technique with a Nissen fundoplication (N-Sleeve) vs conventional sleeve gastrectomy technique
- Conditions
- Severe Obesity, GERD, Bariatric Surgery Candidate, Morbid Obesity
- Trial name
- N'SLEEVE (NCT04626232)
- Testing
- N-SLEEVE technique, SLEEVE
- Where
- France
- Volunteers
- 2 people
- Sponsor
- University Hospital, Montpellier
Gastroesophageal Reflux
Laparoscopic Nissen Fundoplication Comparing Division Versus Non-Division of Short Gastric Vessels
Recently, total fundoplication followed by laparoscopic esophageal hiatoplasty has been the most common surgical treatment for gastro-esophageal reflux.
- Trial name
- NCT00852098
- Testing
- Lap Nissen fundoplication with division of short gastric vessels, Laparoscopic Nissen fundoplication without division of short gastric vessels
- Where
- 2 sites in Brazil
- Volunteers
- 2 people
- Sponsor
- Federal University of São Paulo
Hypopharyngeal Mean Pressure
Applying High Resolution Impedance Manometry for Perioperative Swallowing Changes in Older Patients Receiving Endotracheal Intubation or Supraglottic Airway Devices During Orthopedic Surgery
We aimed to investigate whether patients with tracheal intubation has high hypopharyngeal pressure than patients with supraglottic airway does by using high resolution impedance manometry.
- Trial name
- NCT05420428
- Testing
- supraglottic airway device, endotracheal intubation
- Where
- Taiwan
- Volunteers
- 32 people
- Sponsor
- National Taiwan University Hospital
Gastro-Oesophageal Reflux Disease
PPI Sequencing Study
The purpose of this study is to assess how patients with gastro-oesophageal reflux disease (heartburn) who are currently receiving treatment with a proton pump inhibitor but are still experiencing symptoms will benefit from a…
- Trial name
- NCT00384592
- Testing
- Esomeprazole, Physical exam, Pregnancy test if applicable
- Where
- 14 sites in United Kingdom
- Volunteers
- 100 people
- Sponsor
- AstraZeneca
Gastro Esophageal Reflux, Barrett Esophagus
PPI Therapy Impact on GERD After Sleeve Gastrectomy
The trial would to try to establish: The best post-operative PPI prescription protocol after Sleeve Gastrectomy The impact of PPI therapy on postoperative peptic diseases (erosive gastropathies, ulcers, duodenitis, esophagitis…
- Conditions
- Gastro Esophageal Reflux, Barrett Esophagus, Bariatric Surgery Candidate
- Trial name
- NCT04400136
- Testing
- Lansoprazole oral tablets 30 mg
- Where
- Italy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Fibromyalgia, Irritable Bowel Syndrome
Patient-reported Outcome Measures (PROMs) in Patients With Bodily Stress Syndrome: Protocol for a Prospective Cohort Study
This cohort study implements patient reported outcome measures (PROMs) for patients with bodily stress syndrome in a clinic for functional disorders.
- Conditions
- Fibromyalgia, Irritable Bowel Syndrome, Somatic Symptom, Chronic Fatigue Syndrome
- Trial name
- SYMPA (NCT04667611)
- Testing
- Psychosocial interventions
- Where
- Finland
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Gastroesophageal Reflux
German PMS Trial (AWB) to Evaluate Therapy in Reflux Disease and NSAR-Symptoms
This PMS study had the objective to evaluate under ordinary medical care conditions the efficacy and tolerability of esomeprazole in patients who where treated by general practitioners and internists.
- Trial name
- NCT00567021
- Volunteers
- 67,130 people
- Sponsor
- AstraZeneca
Gastro Esophageal Reflux
Near Focus NBI-Driven Artificial Intelligence for the Diagnosis of Gastro-Oesophageal Reflux Disease
Gastro-oesophageal reflux disease (GORD) is a chronic condition with symptoms arising secondary to the reflux of stomach contents (Vakil et al., 2006).
- Trial name
- NCT04268719
- Testing
- wireless pH capsule recording
- Where
- United Kingdom
- Volunteers
- 76 people
- Sponsor
- King's College Hospital NHS Trust
Dysphagia, Parkinson Disease
A Digital Therapeutic Platform for Swallowing and Drooling Problems in Parkinson's
The purpose of this study is the development and early-stage validation of a wearable sensor for dysphagia in patients with PD.
- Trial name
- NCT04664634
- Testing
- Aria Sensor
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Northwestern University
GERD (Gastroesophageal Reflux Disease)
A Comparison of Cosmos Rx Medication Adherence Platform vs. Pharmacy Fill Adherence Measures
Medication non-adherence is associated with greater morbidity and mortality in chronic disease, and has been estimated to increase healthcare costs by over $170 billion annually in the United States.1 Medication adherence is…
- Trial name
- NCT07712614
- Testing
- Fortiskap
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Cosmos Rx, Inc
Morbid Obesity, Gastroesophageal Reflux Disease
Effect of RING on Gastroesophageal Reflux (GERD) After RYGBP
Silastic rings have been used around the gastric pouch in order to promote better weight loss after Roux-and-Y gastric bypass surgery ( RYGBP).
- Conditions
- Morbid Obesity, Gastroesophageal Reflux Disease, Vomiting
- Trial name
- RING (NCT01212835)
- Testing
- RYGBP-RING
- Where
- 3 sites in Brazil
- Volunteers
- 114 people
- Sponsor
- Clinica Gastrobese
Airway Disease, Barrett Esophagus
Biomarkers of Airway Disease, Barrett's and Underdiagnosed Reflux Noninvasively (BADBURN)
A majority of Fire Department of New York (FDNY) World Trade Center (WTC) exposed rescue and recovery workers developed gastroesophageal reflux disease (GERD), a risk factor for Barrett's Esophagus (BE) and subsequent esophageal…
- Conditions
- Airway Disease, Barrett Esophagus, Gastroesophageal Reflux Disease
- Trial name
- NCT05216133
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- NYU Langone Health
Oropharyngeal Cancer
Assessment of Swallowing Function and Quality of Life in Oropharyngeal Cancer Patients Treated by Chemo-radiotherapy
Open-label, interventional, multicentric, randomized, phase III study. Cancer studied is the oropharyngeal cancer. Study is composed by 2 arms of subjects: prophylactic or reactive percutaneous endoscopic gastrostomy tube…
- Trial name
- SwallPEG (NCT04019548)
- Testing
- Percutaneous Endoscopic Gastrotomy tube placement, Cisplatin injection, Radiotherapy
- Where
- 2 sites in Belgium
- Volunteers
- 110 people
- Sponsor
- Jules Bordet Institute
Gastroesophageal Reflux Disease, Erosive Esophagitis
Safety and Efficacy of Dexlansoprazole Delayed-Release Capsules for Healing of Erosive Esophagitis and Maintenance of Healed Erosive Esophagitis and Relief of Heartburn in Adolescents
The purpose of this study is to assess the safety and effectiveness of treatment with once daily oral administration of dexlansoprazole delayed-release capsules in adolescents with erosive esophagitis (EE) and for maintenance of…
- Trial name
- NCT01642615
- Testing
- Dexlansoprazole
- Where
- 60 sites in United States, Belgium and 6 more
- Volunteers
- 63 people
- Sponsor
- Takeda
Deglutition Disorders
A Study on Building a Voice Cohort for the Development of a Non-face-to-face Machine Learning Diagnostic and Monitoring Platform Using Voice Analysis and Various Sensors in Patients With Dysphagia.
Collection of basic data for real-time analysis and monitoring by measuring what changes in voice occur according to the state of dysphagia using voice analysis and various sensors.
- Trial name
- NCT05439447
- Testing
- Voice recording and sensor-based data collection
- Where
- South Korea
- Volunteers
- 259 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Oropharyngeal Dysphagia
Design and Implementation of a Nutritional Intervention in Patients With Oropharyngeal Dysphagia
The purpose of this trial is to design, implement and evaluate the effect of a nutritional intervention in patients with Oropharyngeal Dysphagia on body composition and oral intake of energy and protein.
- Trial name
- NCT02959450
- Testing
- Modified consistency and volume diet
- Where
- Mexico
- Volunteers
- 127 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Gerd, Eosinophilic Esophagitis
Utility of Mucosal Impedance Device in Chronic Esophageal Disorders:
Background \& Significance Chronic benign esophageal disorders such as Gastroesophageal reflux disease (GERD) and eosinophilic esophagitis are common gastrointestinal disorders affecting nearly 20% and 0.1% of the population…
- Trial name
- NCT07227506
- Testing
- MuVI Esophageal mucosal impedance testing
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
GERD
Understanding the Pathophysiology and Effects of Diaphragmatic Breathing in Upright Gastroesophageal Reflux
This study aims to understand why patients have predominantly upright gastroesophageal reflux disease by comparing such patients to healthy persons AND whether a behavioral intervention (diaphragmatic breathing) will impact this…
- Trial name
- NCT02972047
- Testing
- Diaphragmatic Breathing
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Dysphagia
Comprehensive Oral Care Long-term Care Facilities
Oral care is a common way of caring for long-term care facility residents, particularly for those with swallowing difficulties, as oral health is closely related to eating function.
- Trial name
- NCT06606548
- Testing
- comprehensive oral care
- Where
- Taiwan
- Volunteers
- 91 people
- Sponsor
- National Taiwan University Hospital
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