Clinical trials: DM
Diabetes Mellitus, Osteoporosis
Type 1 Diabetes Mellitus Effect on Bone Mineral Density
Because the diabetics are fracturing at a younger age than the general population (12), this leads us to believe there are significant factors that lead to fracture in Type 1 diabetes mellitus (DM) other than bone mineral density…
- Trial name
- NCT01633684
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Creighton University
Diabetes (Insulin-requiring, Type 1 or Type 2), Pediatric Diabetes
A Novel Miniature Equine-Assisted Diabetes Education Program for Youth: Evaluating the Diabetes Equine Empowerment Program (DEEP).
The Diabetes \& Equine Empowerment Program (DEEP) is a research study evaluating a novel diabetes education program that combines hands-on interactions with miniature horses and evidence-based diabetes self-management education…
- Conditions
- Diabetes (Insulin-requiring, Type 1 or Type 2), Pediatric Diabetes, Diabetes (DM)
- Trial name
- DEEP (NCT07822555)
- Testing
- Diabetes & Equine Empowerment Program (DEEP)
- Volunteers
- 50 people
- Sponsor
- Nemours Children's Clinic
Diabetes Mellitus, Type 2
Lifestyle Intervention For Effective Diabetes Management
Chronic disease management programs are shown to reduce mortality, recurrent hospitalizations, and improve indirect societal costs among specific subgroups of the population.
- Trial name
- LIFE-DM (NCT00813930)
- Testing
- INTERxVENT lifestyle modification program
- Where
- 3 sites in Canada
- Volunteers
- 50 people
- Sponsor
- Unity Health Toronto
Type 2 Diabetes Mellitus
Cilostazol Versus Aspirin for Primary Prevention of Atherosclerotic Events
This multi-center, randomized controlled study aims to evaluate the efficacy of Cilostazol versus Aspirin for primary prevention of atherosclerotic events with Korean type 2 Diabetes Mellitus (DM) patients.
- Trial name
- CAPPA (NCT00886574)
- Testing
- Cilostazol, Aspirin
- Where
- 6 sites in South Korea
- Volunteers
- 400 people
- Sponsor
- Hanyang University
Diabetes Mellitus, Heart Failure
Results of Tc99m-Maraciclatide Scintigraphy in Subjects With Diabetes Mellitus and Heart Failure With Preserved Left Ventricular Ejection Fraction
The purpose of this study is to evaluate the results of 99mTc maraciclatide scintigraphy in diabetic subjects with HFPEF. A maximum of 20 subjects with Diabetes Mellitus (DM) and Heart Failure With Preserved Left Ventricular…
- Trial name
- NCT01440517
- Testing
- Tc99m-Maraciclatide
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- GE Healthcare
Pre-diabetes, Diabetes
RCT of SMS for Drivers With Pre-DM
The purpose of this study is to prevent the professional drivers from pre-diabetes to diabetes.
- Trial name
- NCT01556880
- Testing
- Short Message Service (SMS)
- Where
- 3 sites in Hong Kong
- Volunteers
- 104 people
- Sponsor
- The University of Hong Kong
Type-2 Diabetes, Diabetic Retinopathy
Phenotypes of Nonproliferative Diabetic Retinopathy in DM 2 Patients Identified by OCT, CFP, RLA and mfERG (DIAMARKER)
To characterise phenotypes of Non Proliferative Diabetic Retinopathy (NPDR) progression using multimodal testing/imaging procedures.
- Trial name
- NCT01440660
- Where
- Portugal
- Volunteers
- 20 people
- Sponsor
- Association for Innovation and Biomedical Research on Light and Image
Diabetes Mellitus, Non-Insulin-Dependent
Study to Assess the Efficacy and Safety of Sitagliptin Added to the Regimen of Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin (0431-189)
After 24 weeks of treatment, to assess the A1C-lowering efficacy of sitagliptin 100 mg once daily added to the regimen of patients with inadequate glycemic control on metformin monotherapy
- Trial name
- NCT00875394
- Testing
- sitagliptin phosphate, Comparator: metformin, Comparator: Antidiabetic Standard of Care
- Volunteers
- 68 people
- Sponsor
- Merck Sharp & Dohme LLC
Coronary Artery Disease, Diabete Mellitus
The Efficacy of SGLT-2 Inhibitor in Patients With CAD and DM Undergoing PCI.
The study is to compare the effects of SGLT-2 inhibitors and other oral hypoglycemic agents in patients with coronary heart disease and diabetes mellitus undergoing percutaneous coronary intervention.
- Trial name
- NCT05333159
- Testing
- SGLT2 inhibitor
- Where
- China
- Volunteers
- 1,424 people
- Sponsor
- Beijing Anzhen Hospital
Type 2 DM
Carbohydrate Quality and Its Impact on Sleep and Depression in Type 2 Diabetes
The aim of this study was to evaluate the effect of carbohydrate quality on sleep quality and depression in patients with Type 2 diabetes.
- Trial name
- NCT06666205
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Ankara Yildirim Beyazıt University
Diabetes Mellitus, Pre Diabetes
Development and Validation of DM and Pre-DM Risk Prediction Model
Many DM and pre-DM remain undiagnosed. The aim is to develop and validate a risk prediction function to detect DM and pre-DM in Chinese adults aged 18-84 in primary care (PC). The objectives are to: 1.
- Trial name
- NCT04881383
- Testing
- OGTT and HbA1c
- Where
- Hong Kong
- Volunteers
- 1,014 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Metabolic Syndrome
Relation Between Serum Uric Acid and Metabolic Syndrome in Type 2 DM
This study will be undertaken to evaluate the association of serum uric acid (SUA) level with metabolic risk factors in patients with type 2 diabetes and their relation to eGFR status
- Trial name
- NCT04575389
- Testing
- Serum uric acid levels ,HBA1C , fasting plasma glucose ,lipid profile , creatinine level
- Volunteers
- 100 people
- Sponsor
- Assiut University
Pancreatitis, Chronic, Pancreatitis, Acute
Pioglitazone Versus Empagliflozin for Chronic Pancreatitis/Recurrent Acute Pancreatitis/Acute Pancreatitis Associated Diabetes Mellitus
The purpose of this study is to evaluate efficacy of pioglitazone (PIO) versus empagliflozin (EMPA) to improve glycemic control in people with Chronic Pancreatitis (CP) or Recurrent Acute Pancreatitis (RAP) or Acute Pancreatitis…
- Conditions
- Pancreatitis, Chronic, Pancreatitis, Acute, Diabetes Mellitus
- Trial name
- PEP-DM (NCT06729996)
- Testing
- Pioglitazone (PIO), Empagliflozin (EMPA)
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Subjects With Mild Hypertriglyceridemia in Type 2 DM
Consumption of Whole Grains and Legumes Modulates the Genetic Effect of the APOA5 -1131C Variant
We examined whether a substitution of whole grains and legumes for refined rice in a high carbohydrate diet (about 65% of energy derived from carbohydrate) may modify the effect of this variant on changes in apolipoprotein A-V…
- Trial name
- NCT01784952
- Testing
- Dietary intervention
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Yonsei University
Type 2 Diabetes Mellitus
Effect of Internet Therapeutic Intervention on A1C Levels in Type 2 Diabetes Mellitus (DM) on Combination Oral Therapy
This project will test the effectiveness of an Internet based glucose monitoring system on the A1C levels of patients with type 2 diabetes.
- Trial name
- NCT01060241
- Testing
- Internet Intervention
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Endocrine Research Society
Non-Alcoholic Fatty Liver Disease, Diabetes Mellitus
Iron Depletion Therapy for Type 2 DM and NAFLD
The purpose of this study is to find out whether lowering the amount of iron in the body will result in less resistance to insulin and improved liver function in patients with type 2 diabetes mellitus and non-alcoholic fatty…
- Trial name
- NCT00230087
- Testing
- blood donation
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Dermatomyositis
Severity Factors of Dermatomyositis in the Caribbean Population - DM-ANTILLES
Dermatomyositis is a rare chronic autoimmune and inflammatory disease that affects the skin and striated muscles. Its prognosis is linked to visceral involvement (lungs, heart, and oropharyngeal region) and to the possible…
- Trial name
- DM-ANTILLES (NCT07265999)
- Where
- Guadeloupe
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Universitaire de la Guadeloupe
Diabetes Mellitus (DM)
Metatarsal Phalangeal Joint Deformity Progression - R01
The purpose of this research study is to determine the relationships between foot muscle, foot motion, and toe deformity. Results from this investigation will help the investigators to understand what contributes to foot…
- Trial name
- NCT02616263
- Testing
- Foot exercise, Shoulder exercise
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Washington University School of Medicine
Diabetes (DM)
Evaluation of the Impact of a Food is Medicine Program on Diabetes-related Health Outcomes for People With Type 2 Diabetes in a Low Income Community-based Setting Compared to Usual Care
The goal of this clinical trial is to learn if a food is medicine intervention (Healthy Food Rx) improves diabetes-related outcomes in adults diagnosed with type 2 diabetes in a low-income, community-based setting more than usual…
- Trial name
- NCT07529184
- Testing
- Food is medicine
- Where
- United States
- Volunteers
- 405 people
- Sponsor
- Public Health Institute Center for Wellness and Nutrition
Diabetes (DM), Diabetic Ketoacidosis
Phase 1 Trial of Arginine Hydrochloride for the Management of Diabetic Ketoacidosis in Type 2 Diabetes
Diabetic ketoacidosis (DKA) is increasingly recognized in adults with "ketone-prone" type 2 diabetes. In many of these patients, the pancreas can still make insulin but becomes temporarily "stunned" during severe, prolonged high…
- Conditions
- Diabetes (DM), Diabetic Ketoacidosis, Ketosis Prone Diabetes, Hyperglycaemia (Diabetic)
- Trial name
- NCT07167693
- Testing
- Arginine hydrochloride, Sodium Chloride 0.9%
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- David K Carroll