Clinical trials: DM
Obesity, Type 2 Diabetes
Maternal Adipose Tissue and Placental Dysfunction Programs the Fetus for Type 2 Diabetes (PlacentA-DM)
The purpose of this study is to discover the characteristics of pregnant women which increases risk for their babies to develop diabetes, later on in life.
- Trial name
- PlacentA-DM (NCT02211651)
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Type 2 Diabetes Mellitus
Glycemic Control and Complications in Diabetes Mellitus Type 2 (VADT)
This study is a prospective, 2-arm, randomized controlled trial to determine whether glycemic control, achieved through intensification of treatment, is effective in preventing clinical macrovascular complications in patients…
- Trial name
- VADT (NCT00032487)
- Testing
- Insulin, Glimepiride, Rosiglitazone
- Where
- 21 sites in United States, Puerto Rico
- Volunteers
- 1,791 people
- Sponsor
- VA Office of Research and Development
Diabetes Mellitus, Atherosclerosis
Aliskiren's Effect on Arterial Stiffness and Platelet Function in Patients With Diabetes Mellitus (DM)
Aliskiren is a novel renin inhibitor approved for the treatment of hypertension. The effect of aliskiren on arterial stiffness, inflammation and oxidative stress has not been fully investigated yet.The aim of this study is to…
- Trial name
- NCT00732407
- Testing
- aliskiren, losartan
- Volunteers
- 40 people
- Sponsor
- Assaf-Harofeh Medical Center
Acute Ischemic Stroke, Diabetes (DM)
CGM in Acute Ischemic Stroke
The goal of this randomized clinical trial is to evaluate whether continuous glucose monitoring (CGM) can be used to guide glucose management in patients with type 2 diabetes who are admitted with an acute ischemic stroke and…
- Conditions
- Acute Ischemic Stroke, Diabetes (DM), Diabetes Type 2, Hyperglycemia
- Trial name
- SENSTROKE (NCT07510919)
- Testing
- Continuous Glucose Monitoring, Point-of-Care Testing
- Volunteers
- 82 people
- Sponsor
- Isala
End Stage Renal Disease
Influence of DM on Artery Blood Flow and Complications After Radial Artery Cannulation
In atherosclerotic patients undergoing kidney transplantation, arterial cannulation is commonly performed for continuous monitoring of systemic blood pressure and intermittent assessment of arterial blood gases.
- Trial name
- NCT01897857
- Testing
- duplex Doppler ultrasonography
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Yonsei University
Type 2 Diabetes Mellitus, Diabetic Nephropathy
Study of FibroGen (FG)-3019 in Subjects With Type 2 Diabetes Mellitus and Kidney Disease on ACEi and/or ARB Therapy
The purpose of this study is to evaluate the effect of FG-3019 on diabetic kidney disease or diabetic nephropathy.
- Conditions
- Type 2 Diabetes Mellitus, Diabetic Nephropathy, Diabetic Kidney Disease
- Trial name
- NCT00913393
- Testing
- FG-3019
- Where
- 28 sites in United States
- Volunteers
- 46 people
- Sponsor
- Kyntra Bio
Type 1 Diabetes, Hypoglycemia Associated Autonomic Failure
Hypoglycemia Associated Autonomic Failure in Type 1 Diabetes Mellitus (DM)
Exercise is a cornerstone of diabetes management. It helps reduce blood pressure, promote weight loss, lower insulin resistance and improve glucose and lipid (triglyceride and HDL-cholesterol) profiles.
- Trial name
- NCT01672255
- Testing
- Fluoxetine
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Diabetes
Cinnamon Bark, Water-Soluble Cinnamon Extract, and Metformin for Treatment of Type 2 DM.
The purpose of this study is to assess whether Cinnamon bark or water-soluble cinnamon is an effective nutraceutical for the initial treatment of diabetes when compared to standard therapy of Metformin.
- Trial name
- NCT01302743
- Testing
- Group 1: Metformin, Group 2: Cinnamon Bark, Group 3: Cinnulin PF
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Mike O'Callaghan Military Hospital
Type II Diabetes
SOKARY Mobile Application With Type II Diabetes
Android mobile application named (SOKARY)
- Trial name
- DM (NCT04843592)
- Testing
- SOKARY Mobile
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Magda Bayoumi
Prediabetes, Vitamin D Deficiency
Oral Cholecalciferol in Prevention of Type 2 Diabetes Mellitus
Type 2 diabetes mellitus (T2DM) is a major public health problem .Prevalence of vitamin D deficiency is also high i.e. 78-96% in different groups of population in north India.
- Trial name
- NCT01436916
- Testing
- oral cholecalciferol + life style counselling
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Diabetes (DM)
Feasibility Trial of a Sub-conjunctival Insert
The purpose of this single-centre, open label prospective study is to investigate a novel ocular mini insert (OMI) for detection of blood glucose levels in human subjects.
- Trial name
- OMI (NCT07105332)
- Testing
- OMI and Photometer
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- EyeSense GmbH
NAFLD
HOMA-IR as a Screening Test in NAFLD
The aim of this study is to evaluate the role of HOMA-IR in diagnosis of NAFLD in patients with type 2 DM.
- Trial name
- NCT04084925
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Fayoum University
Diabetes Mellitus
The Effect of NVFS on GC in Individuals With DM: SR & MA of RCTs
Purpose of Study (The Effect of Non-Viscous Fibre Supplementation on Glycemic Control (NVFS \& GC) in Individuals with Diabetes Mellitus.
- Trial name
- NVFS&GC (NCT03259724)
- Where
- Canada
- Volunteers
- 514 people
- Sponsor
- Unity Health Toronto
Obesity, Type 2 Diabetes
Low Carbohydrate Diet Compared to Calorie and Fat Restricted Diet in Patients With Obesity and Type II Diabetes
This study is designed to address the hypothesis that in obese patients with type 2 diabetes mellitus (DM), a low carbohydrate diet not specifically restricted in calories compared to low fat, caloric restricted diet over 24…
- Conditions
- Obesity, Type 2 Diabetes, Hyperlipidemia
- Trial name
- NCT00108459
- Testing
- Low Carbohydrate Diet
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- US Department of Veterans Affairs
Coronary Artery Disease, Diabete Mellitus
The Efficacy of SGLT-2 Inhibitor in Patients With CAD and DM Undergoing PCI.
The study is to compare the effects of SGLT-2 inhibitors and other oral hypoglycemic agents in patients with coronary heart disease and diabetes mellitus undergoing percutaneous coronary intervention.
- Trial name
- NCT05333159
- Testing
- SGLT2 inhibitor
- Where
- China
- Volunteers
- 1,424 people
- Sponsor
- Beijing Anzhen Hospital
Diabetes Mellitus, Type 2, Diastolic Dysfunction
PDD in Type 2 Diabetes w/wo Diastolic Dysfunction
This study will advance the investigator's knowledge of the integrated cardiorenal and humoral physiology in type 2 diabetic patients with and without pre-clinical diastolic dysfunction, and test a novel therapeutic strategy…
- Trial name
- NCT03744975
- Testing
- LCZ 696
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Diabetes (DM)
Studies of Insulin and Glucagon Action in the Liver
This study examines how glucagon works to regulate glucose metabolism, based on new findings that suggest glucagon signaling in the liver has more than one role, and that these multiple roles can be opposing in nature.
- Trial name
- SIGNAL (NCT07300982)
- Testing
- Glucagon
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Duke University
Pre-diabetes, Diabetes
RCT of SMS for Drivers With Pre-DM
The purpose of this study is to prevent the professional drivers from pre-diabetes to diabetes.
- Trial name
- NCT01556880
- Testing
- Short Message Service (SMS)
- Where
- 3 sites in Hong Kong
- Volunteers
- 104 people
- Sponsor
- The University of Hong Kong
Diabetes Mellitus Type 2
Effect of Androgel on Type 2 Diabetic Males With Hypogonadism
This is to study the effect of replacing testosterone on different inflammatory cells in type 2 diabetics with low testosterone levels.
- Trial name
- NCT00350701
- Testing
- androgel, androgel 10g
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- University at Buffalo
Polycystic Ovary Syndrome, Morbid Obesity
The Female Health Dietary Intervention Study
This study has two phases: 1. In phase 1 of the study (8 weeks),the effect of two different low calorie diets on manifestations of PCOS, including risk factors for the metabolic syndrome and cardiovascular risk profile will be…
- Trial name
- FEMIN (NCT00779571)
- Testing
- Crispbread
- Where
- Norway
- Volunteers
- 61 people
- Sponsor
- The Hospital of Vestfold